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Gene-Chemical Interaction Annotations
Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of DDC mRNA | CTD | PMID:15834898 PMID:15901920 | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of DDC mRNA | CTD | PMID:20068009 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:10469 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DDC mRNA | CTD | PMID:19933214 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DDC mRNA | CTD | PMID:19490992 more ... | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DDC mRNA | CTD | PMID:19490992 more ... | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:10469 | 6480464 | Tetrachlorodibenzodioxin affects the expression of DDC mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:734177 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DDC mRNA | CTD | PMID:20106945 PMID:21632981 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DDC mRNA | CTD | PMID:19490992 PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of DDC mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:10469 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DDC mRNA | CTD | PMID:19933214 PMID:19770486 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:10469 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DDC mRNA | CTD | PMID:19770486 PMID:19933214 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DDC mRNA | CTD | PMID:19490992 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:734177 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DDC mRNA | CTD | PMID:20106945 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2,4-dinitrotoluene affects the expression of DDC mRNA | CTD | PMID:21346803 | 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine | decreases activity | EXP | | 6480464 | Puromycin Aminonucleoside results in decreased activity of DDC protein | CTD | PMID:16204272 | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of DDC mRNA | CTD | PMID:20959002 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | RGD:10469 | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of DDC mRNA | CTD | PMID:20188158 | aflatoxin B1 | affects expression | ISO | RGD:734177 | 6480464 | Aflatoxin B1 affects the expression of DDC protein | CTD | PMID:20106945 | aflatoxin B1 | decreases expression | ISO | RGD:734177 | 6480464 | Aflatoxin B1 results in decreased expression of DDC mRNA | CTD | PMID:21632981 more ... | aflatoxin B1 | decreases expression | ISO | RGD:734177 | 6480464 | Aflatoxin B1 results in decreased expression of DDC mRNA | CTD | PMID:21641981 | aflatoxin B1 | increases expression | ISO | RGD:10469 | 6480464 | Aflatoxin B1 results in increased expression of DDC mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | increases expression | ISO | RGD:10469 | 6480464 | Tretinoin results in increased expression of DDC mRNA | CTD | PMID:16604517 | all-trans-retinoic acid | increases expression | ISO | RGD:734177 | 6480464 | Tretinoin results in increased expression of DDC mRNA | CTD | PMID:21934132 | ammonium chloride | decreases expression | EXP | | 6480464 | Ammonium Chloride results in decreased expression of DDC protein | CTD | PMID:16483693 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of DDC mRNA | CTD | PMID:16483693 | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of DDC mRNA | CTD | PMID:8717341 | andrographolide | increases expression | ISO | RGD:10469 | 6480464 | andrographolide results in increased expression of DDC mRNA | CTD | PMID:19737545 | andrographolide | multiple interactions | ISO | RGD:10469 | 6480464 | [andrographolide co-treated with beta-Naphthoflavone] results in increased expression of DDC mRNA | CTD | PMID:19737545 | benzo[a]pyrene | decreases expression | ISO | RGD:734177 | 6480464 | Benzo(a)pyrene results in decreased expression of DDC mRNA | CTD | PMID:20106945 | benzo[a]pyrene | increases expression | ISO | RGD:10469 | 6480464 | Benzo(a)pyrene results in increased expression of DDC mRNA | CTD | PMID:19770486 PMID:22610609 | benzo[a]pyrene | decreases expression | ISO | RGD:734177 | 6480464 | Benzo(a)pyrene results in decreased expression of DDC mRNA | CTD | PMID:20106945 more ... | benzo[a]pyrene | decreases expression | ISO | RGD:734177 | 6480464 | Benzo(a)pyrene results in decreased expression of DDC mRNA | CTD | PMID:20106945 PMID:22316170 | benzo[a]pyrene | increases expression | ISO | RGD:10469 | 6480464 | Benzo(a)pyrene results in increased expression of DDC mRNA | CTD | PMID:19770486 | benzo[a]pyrene | multiple interactions | ISO | RGD:10469 | 6480464 | [Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] results in decreased expression of DDC mRNA | CTD | PMID:21715664 | benzo[a]pyrene | increases expression | ISO | RGD:734177 | 6480464 | Benzo(a)pyrene results in increased expression of DDC mRNA | CTD | PMID:17879257 | cadmium dichloride | affects expression | EXP | | 6480464 | Cadmium Chloride affects the expression of DDC mRNA | CTD | PMID:22110744 | cadmium sulfate | increases expression | ISO | RGD:10469 | 6480464 | cadmium sulfate results in increased expression of DDC mRNA | CTD | PMID:16221973 | carbonyl sulfide | decreases expression | EXP | | 6480464 | carbonyl sulfide results in decreased expression of DDC mRNA | CTD | PMID:19395590 | cefaloridine | decreases expression | EXP | | 6480464 | Cephaloridine results in decreased expression of DDC mRNA | CTD | PMID:18500788 | clozapine | multiple interactions | ISO | RGD:10469 | 6480464 | Clozapine results in increased expression of and results in increased activity of DDC protein | CTD | PMID:16415089 | clozapine | increases expression | ISO | RGD:10469 | 6480464 | Clozapine results in increased expression of DDC mRNA | CTD | PMID:16415089 | copper atom | multiple interactions | ISO | RGD:734177 | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of DDC mRNA | CTD | PMID:20971185 | copper atom | decreases expression | EXP | | 6480464 | Copper results in decreased expression of DDC mRNA | CTD | PMID:22465980 | copper(0) | multiple interactions | ISO | RGD:734177 | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of DDC mRNA | CTD | PMID:20971185 | copper(0) | decreases expression | EXP | | 6480464 | Copper results in decreased expression of DDC mRNA | CTD | PMID:22465980 | copper(2+) sulfate | decreases expression | ISO | RGD:734177 | 6480464 | Copper Sulfate results in decreased expression of DDC mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | RGD:734177 | 6480464 | Cyclosporine results in decreased expression of DDC mRNA | CTD | PMID:20106945 | cyclosporin A | decreases expression | ISO | RGD:734177 | 6480464 | Cyclosporine results in decreased expression of DDC mRNA | CTD | PMID:20106945 PMID:21632981 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of DDC mRNA | CTD | PMID:21266533 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of DDC mRNA | CTD | PMID:17379624 PMID:21266533 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of DDC protein | CTD | PMID:15728792 | dichlorine | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] affects the expression of DDC mRNA | CTD | PMID:18636392 | dichlorine | decreases expression | EXP | | 6480464 | Chlorine results in decreased expression of DDC mRNA | CTD | PMID:18636392 | dioxygen | decreases expression | ISO | RGD:734177 | 6480464 | Oxygen deficiency results in decreased expression of DDC mRNA | CTD | PMID:19695866 | genistein | increases expression | ISO | RGD:734177 | 6480464 | Genistein results in increased expression of DDC mRNA | CTD | PMID:15378649 | gold atom | multiple interactions | ISO | RGD:10469 | 6480464 | [Gold co-treated with Polyethylene Glycols] results in decreased expression of DDC mRNA | CTD | PMID:19695318 | gold(0) | multiple interactions | ISO | RGD:10469 | 6480464 | [Gold co-treated with Polyethylene Glycols] results in decreased expression of DDC mRNA | CTD | PMID:19695318 | indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of DDC mRNA | CTD | PMID:21396975 | isotretinoin | decreases expression | ISO | RGD:734177 | 6480464 | Isotretinoin results in decreased expression of DDC mRNA | CTD | PMID:20436886 | ketanserin | increases activity | ISO | RGD:10469 | 6480464 | Ketanserin results in increased activity of DDC protein | CTD | PMID:16415089 | lead diacetate | decreases expression | EXP | | 6480464 | lead acetate results in decreased expression of DDC mRNA | CTD | PMID:22641619 | menadione | affects expression | ISO | RGD:734177 | 6480464 | Vitamin K 3 affects the expression of DDC mRNA | CTD | PMID:20044591 | metergoline | increases activity | ISO | RGD:10469 | 6480464 | Metergoline results in increased activity of DDC protein | CTD | PMID:16415089 | N-nitrosodiethylamine | decreases expression | ISO | RGD:734177 | 6480464 | Diethylnitrosamine results in decreased expression of DDC mRNA | CTD | PMID:21527772 | nitric oxide | increases activity | EXP | | 6480464 | Nitric Oxide deficiency results in increased activity of DDC protein | CTD | PMID:7541690 | ozone | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] affects the expression of DDC mRNA | CTD | PMID:18636392 | paracetamol | affects expression | ISO | RGD:10469 | 6480464 | Acetaminophen affects the expression of DDC mRNA | CTD | PMID:17562736 | paraquat | decreases expression | ISO | RGD:10469 | 6480464 | Paraquat results in decreased expression of DDC mRNA | CTD | PMID:21371552 | perfluorooctane-1-sulfonic acid | decreases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in decreased expression of DDC mRNA | CTD | PMID:18692542 | perfluorooctanoic acid | decreases expression | EXP | | 6480464 | perfluorooctanoic acid results in decreased expression of DDC mRNA | CTD | PMID:19162173 | permethrin | decreases expression | EXP | | 6480464 | Permethrin results in decreased expression of DDC mRNA | CTD | PMID:19017407 | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of DDC mRNA | CTD | PMID:12807726 | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of DDC mRNA | CTD | PMID:19162173 | phenobarbital | decreases expression | ISO | RGD:10469 | 6480464 | Phenobarbital results in decreased expression of DDC mRNA | CTD | PMID:19270015 | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of DDC mRNA | CTD | PMID:19162173 | quercetin | decreases expression | ISO | RGD:734177 | 6480464 | Quercetin results in decreased expression of DDC mRNA | CTD | PMID:21632981 | reserpine | increases expression | EXP | | 6480464 | Reserpine results in increased expression of DDC mRNA | CTD | PMID:1359376 | resveratrol | increases expression | ISO | RGD:734177 | 6480464 | resveratrol results in increased expression of DDC mRNA | CTD | PMID:18586690 | S-adenosyl-L-methionine | multiple interactions | ISO | RGD:734177 | 6480464 | [Levodopa co-treated with DDC] results in increased abundance of S-Adenosylmethionine | CTD | PMID:11445284 | scopolamine | decreases expression | EXP | | 6480464 | Scopolamine Hydrobromide results in decreased expression of DDC mRNA | CTD | PMID:17540011 | sodium dichromate | affects expression | EXP | | 6480464 | sodium bichromate affects the expression of DDC mRNA | CTD | PMID:22110744 | tamoxifen | affects expression | ISO | RGD:10469 | 6480464 | Tamoxifen affects the expression of DDC mRNA | CTD | PMID:20937368 | trans-resveratrol | increases expression | ISO | RGD:734177 | 6480464 | resveratrol results in increased expression of DDC mRNA | CTD | PMID:18586690 | vancomycin | increases expression | ISO | RGD:10469 | 6480464 | Vancomycin results in increased expression of DDC mRNA | CTD | PMID:18930951 | vigabatrin | decreases expression | EXP | | 6480464 | Vigabatrin results in decreased expression of DDC mRNA | CTD | PMID:8717341 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations
Molecular Pathway Annotations
Disease Annotations
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Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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Molecular Pathway Annotations
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| External Database Links | |
| KEGG Pathway | Alcoholism |
| Amphetamine addiction | |
| Cocaine addiction | |
| Dopaminergic synapse | |
| Histidine metabolism | |
| Metabolic pathways | |
| Phenylalanine metabolism | |
| Serotonergic synapse | |
| Tryptophan metabolism | |
| Tyrosine metabolism | |
References - curated| 1. |
J. Inherit. Metab. Dis. 21: 4 only, 1998. |
| 2. |
Borglum AD, etal., Am J Med Genet B Neuropsychiatr Genet 2003 Feb;117(1):18-22. |
| 3. |
Brown ST, etal., J Neurochem. 2009 Jul;110(2):622-30. Epub 2009 May 8. |
| 4. |
Brun L, etal., Neurology. 2010 Jul 6;75(1):64-71. Epub 2010 May 26. |
| 5. |
Cartier EA, etal., J Biol Chem. 2010 Jan 15;285(3):1957-66. Epub 2009 Nov 10. |
| 6. |
Chiou SH, etal., Anal Biochem. 2007 Apr 1;363(1):46-57. Epub 2007 Jan 17. |
| 7. |
Coll M, etal., J Hepatol. 2008 Jul;49(1):43-51. Epub 2008 Apr 18. |
| 8. |
Cruz-Muros I, etal., Exp Neurol. 2007 Mar;204(1):147-61. Epub 2006 Nov 16. |
| 9. |
DasBanerjee T, etal., Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 5;147B(8):1554-63. |
| 10. |
de Lonlay P, etal., J Clin Endocrinol Metab. 2006 Mar;91(3):933-40. Epub 2006 Jan 10. |
| 11. |
Ershov PV, etal., J Chem Neuroanat. 2005 Jul;30(1):27-33. |
| 12. |
Fan DS, etal., Hum Gene Ther. 1998 Nov 20;9(17):2527-35. |
| 13. |
Foster SB, etal., Chem Res Toxicol. 2003 Oct;16(10):1372-84. |
| 14. |
Gil S, etal., Cell Mol Neurobiol. 2010 Aug;30(6):817-25. Epub 2010 Mar 16. |
| 15. |
GOA data from the GO Consortium |
| 16. |
Harrill JA, etal., BMC Genomics. 2008 Nov 18;9:546. |
| 17. |
Hayashi H, etal., Biochemistry. 1993 Jan 26;32(3):812-8. |
| 18. |
Hayashi H, etal., Biochemistry. 1999 Nov 23;38(47):15615-22. |
| 19. |
Ishida Y, etal., Genes Cells 2002 May;7(5):447-59. |
| 20. |
Jin CM, etal., Eur J Pharmacol. 2008 Sep 4;591(1-3):88-95. Epub 2008 Jun 19. |
| 21. |
Jin CM, etal., J Asian Nat Prod Res. 2008 Jul-Aug;10(7-8):747-55. |
| 22. |
KEGG |
| 23. |
Kitahama K, etal., J Chem Neuroanat. 2009 Oct;38(2):130-40. Epub 2009 Jul 7. |
| 24. |
Kvetnansky R, etal., Physiol Rev. 2009 Apr;89(2):535-606. |
| 25. |
Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7 |
| 26. |
Lee JJ, etal., Molecules. 2008 Feb 27;13(2):475-87. |
| 27. |
Moreira-Rodrigues M, etal., Life Sci. 2009 Mar 27;84(13-14):409-14. Epub 2009 Jan 8. |
| 28. |
NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 29. |
Pipeline to import KEGG annotations from KEGG into RGD Pathway Ontology |
| 30. |
RGD automated data pipeline |
| 31. |
RGD automated import pipeline for gene-chemical interactions |
| 32. |
RGD Automated Pipelines |
| 33. |
Rorsman F, etal., Proc Natl Acad Sci U S A 1995 Sep 12;92(19):8626-9. |
| 34. |
Sampaio-Maia B, etal., Nephrol Dial Transplant. 2006 Feb;21(2):314-23. Epub 2005 Oct 4. |
| 35. |
Shen H, etal., Tohoku J Exp Med. 2003 Mar;199(3):149-59. |
| 36. |
Tanaka T, etal., Proc Natl Acad Sci U S A 1989 Oct;86(20):8142-6. |
| 37. |
Tehranian R, etal., J Neurochem. 2006 Nov;99(4):1188-96. Epub 2006 Sep 18. |
| 38. |
Vieira-Coelho MA, etal., Life Sci. 1999;64(1):69-81. |
| 39. |
Yamazaki N and Sudo J, Jpn J Pharmacol. 1988 Feb;46(2):193-6. |
| 40. |
Yang YJ, etal., J Neurosci Res. 2009 Jun;87(8):1929-37. |
References - uncurated
RGD Disease Portals| Ddc has been annotated in the following RGD Disease Portals. |
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Comparative Map Data| Ddc (Rattus norvegicus) |
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| DDC (Homo sapiens) |
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| Ddc (Mus musculus) |
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Position Markers| RH130833 |
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| RH143134 |
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| RH94401 |
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| BF408245 |
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QTLs in Region (RGSC Genome Assembly v3.4)| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | NM_001270852 | (Get FASTA) | Search GEO for Microarray Profiles |
| NM_001270853 | (Get FASTA) | Search GEO for Microarray Profiles | |
| NM_012545 | (Get FASTA) | Search GEO for Microarray Profiles | |
| GenBank Nucleotide | AABR06080494 | (Get FASTA) | Search GEO for Microarray Profiles |
| AABR06080495 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06080496 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06080497 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06080498 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06080499 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01081156 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01081157 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01081158 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01081159 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BC087032 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CH474055 | (Get FASTA) | Search GEO for Microarray Profiles | |
| FQ219697 | (Get FASTA) | Search GEO for Microarray Profiles | |
| JF273828 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L03417 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L32989 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L32990 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L32991 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L32992 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L32993 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L32994 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L32995 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L32996 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L32997 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L32999 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L33000 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L33001 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L33002 | (Get FASTA) | Search GEO for Microarray Profiles | |
| L33003 | (Get FASTA) | Search GEO for Microarray Profiles | |
| M27716 | (Get FASTA) | Search GEO for Microarray Profiles | |
| M84648 | (Get FASTA) | Search GEO for Microarray Profiles | |
| M84649 | (Get FASTA) | Search GEO for Microarray Profiles | |
| U31884 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_012545 | ||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_036677 | ||||||||||||||||||||
| Position: |
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Protein Sequences| Protein RefSeqs | NP_001257781 | (Get FASTA) |
| NP_001257782 | (Get FASTA) | |
| NP_036677 | (Get FASTA) | |
| GenBank Protein | AAA40646 | (Get FASTA) |
| AAA41087 | (Get FASTA) | |
| AAA85565 | (Get FASTA) | |
| AAA99905 | (Get FASTA) | |
| AAH87032 | (Get FASTA) | |
| AEH68229 | (Get FASTA) | |
| EDL76064 | (Get FASTA) | |
| EDL76065 | (Get FASTA) | |
| EDL76066 | (Get FASTA) | |
| EDL76067 | (Get FASTA) | |
| P14173 | (Get FASTA) |
Strain Sequence Variants
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External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSRNOG00000004327 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Protein | ENSRNOP00000005851 | ENTREZGENE, UniProtKB/Swiss-Prot |
| ENSRNOP00000053885 | UniProtKB/TrEMBL | |
| ENSRNOP00000064520 | UniProtKB/Swiss-Prot | |
| Ensembl Transcript | ENSRNOT00000005851 | ENTREZGENE, UniProtKB/Swiss-Prot |
| ENSRNOT00000057051 | UniProtKB/TrEMBL | |
| ENSRNOT00000073892 | UniProtKB/Swiss-Prot | |
| Entrez Gene | 24311 | ENTREZGENE |
| Gene3D-CATH | PyrdxlP-dep_Trfase_major_sub1 | UniProtKB/Swiss-Prot |
| PyrdxlP-dep_Trfase_major_sub2 | UniProtKB/Swiss-Prot | |
| Germonline | ENSRNOG00000004327 | UniProtKB/Swiss-Prot |
| HomoloGene Group ID | 618 | ENTREZGENE |
| IMAGE_CLONE | IMAGE:7098083 | IMAGE-MGC_LOAD |
| InterPro | Aromatic_deC | UniProtKB/Swiss-Prot |
| PyrdxlP-dep_de-COase | UniProtKB/Swiss-Prot | |
| PyrdxlP-dep_Trfase_major_dom | UniProtKB/Swiss-Prot | |
| PyrdxlP-dep_Trfase_major_sub1 | UniProtKB/Swiss-Prot | |
| PyrdxlP-dep_Trfase_major_sub2 | UniProtKB/Swiss-Prot | |
| Pyridoxal-P_BS | UniProtKB/Swiss-Prot | |
| IPI | IPI00470246 | UniProtKB/Swiss-Prot |
| IPI00779983 | UniProtKB/TrEMBL | |
| IPI01027859 | UniProtKB/TrEMBL | |
| KEGG Report | rno:24311 | ENTREZGENE, UniProtKB/Swiss-Prot |
| MGC_CLONE | MGC:93628 | IMAGE-MGC_LOAD |
| Pfam | Pyridoxal_deC | UniProtKB/Swiss-Prot |
| PharmGKB | DDC | RGD |
| PRINTS | YHDCRBOXLASE | UniProtKB/Swiss-Prot |
| PROSITE | DDC_GAD_HDC_YDC | UniProtKB/Swiss-Prot |
| Superfamily-SCOP | PyrdxlP-dep_Trfase_major | UniProtKB/Swiss-Prot |
| UniGene | Rn.11064 | ENTREZGENE |
| UniProt | D3ZMA5_RAT | UniProtKB/TrEMBL |
| DDC_RAT | UniProtKB/Swiss-Prot | |
| Q62819_RAT | UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2008-09-25 | Ddc | dopa decarboxylase (aromatic L-amino acid decarboxylase) | Ddc | dopa decarboxylase | Nomenclature updated to reflect human and mouse nomenclature | 10779 | APPROVED |
| 2002-11-06 | Ddc | dopa decarboxylase | Dopa decarboxylase (aromatic L-amino acid decarboxylase) | Name updated | 2225 | APPROVED | |
| 2002-06-10 | Ddc | Dopa decarboxylase (aromatic L-amino acid decarboxylase) | Symbol and Name status set to approved | 1490 | APPROVED |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_disease | an autoantigen in autoimmune polyendocrine syndrome type I | 727686 |
| gene_other | pyrodoxal phosphate is a cofactor for enzyme activity | 727686 |
| More on Ddc | |
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Entrez Gene |
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Ensembl Gene |
![]() | Genome Browser |
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NCBI Map Viewer |
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Vista |
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Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 2494 |
| Created: | 2000-05-25 |
| Species: | Rattus norvegicus |
| Last Modified: | 2013-04-23 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.




