Rabggtb (Rab geranylgeranyltransferase subunit beta) - Rat Genome Database

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Gene: Rabggtb (Rab geranylgeranyltransferase subunit beta) Rattus norvegicus
Analyze
Symbol: Rabggtb
Name: Rab geranylgeranyltransferase subunit beta
RGD ID: 3530
Description: Enables several functions, including Rab geranylgeranyltransferase activity; small GTPase binding activity; and zinc ion binding activity. Part of Rab-protein geranylgeranyltransferase complex. Orthologous to human RABGGTB (Rab geranylgeranyltransferase subunit beta); INTERACTS WITH 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: geranylgeranyl transferase type II subunit beta; geranylgeranyl transferase type-2 subunit beta; GGTase-II-beta; rab geranyl-geranyltransferase subunit beta; Rab geranylgeranyl transferase componenet, subunit beta; RAB geranylgeranyl transferase, b subunit; Rab geranylgeranyltransferase, beta subunit; rab GG transferase beta; rab GGTase beta; type II protein geranyl-geranyltransferase subunit beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82245,504,586 - 245,510,878 (-)NCBIGRCr8
mRatBN7.22242,844,758 - 242,850,951 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2242,844,762 - 242,851,050 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2250,667,563 - 250,673,774 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02248,561,386 - 248,567,597 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02243,459,951 - 243,466,163 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02260,110,309 - 260,115,574 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2260,110,309 - 260,115,577 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02278,774,376 - 278,779,641 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42251,852,549 - 251,857,811 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12251,867,151 - 251,872,419 (-)NCBI
Celera2234,777,191 - 234,782,459 (-)NCBICelera
Cytogenetic Map2q45NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2,4-trimethylbenzene  (EXP)
1,2-dichloroethane  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
benzene  (EXP)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chloropicrin  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
cobalt dichloride  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
DDT  (ISO)
deguelin  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
dioxygen  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
farnesol  (ISO)
flavonoids  (EXP)
fluoranthene  (ISO)
flutamide  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
GW 4064  (ISO)
ivermectin  (ISO)
leflunomide  (ISO)
methylmercury chloride  (ISO)
oleic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (EXP)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
pyrimidifen  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
sodium arsenite  (EXP)
tamibarotene  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiophenes  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
trovafloxacin  (ISO)
uranium atom  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vitamin K  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. cDNA cloning and expression of the alpha and beta subunits of rat Rab geranylgeranyl transferase. Armstrong SA, etal., J Biol Chem 1993 Jun 5;268(16):12221-9.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation. Guo Z, etal., EMBO J. 2008 Sep 17;27(18):2444-56. doi: 10.1038/emboj.2008.164. Epub 2008 Aug 28.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Structure of Rab escort protein-1 in complex with Rab geranylgeranyltransferase. Pylypenko O, etal., Mol Cell. 2003 Feb;11(2):483-94.
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:10745007   PMID:23114750  


Genomics

Comparative Map Data
Rabggtb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82245,504,586 - 245,510,878 (-)NCBIGRCr8
mRatBN7.22242,844,758 - 242,850,951 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2242,844,762 - 242,851,050 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2250,667,563 - 250,673,774 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02248,561,386 - 248,567,597 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02243,459,951 - 243,466,163 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02260,110,309 - 260,115,574 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2260,110,309 - 260,115,577 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02278,774,376 - 278,779,641 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42251,852,549 - 251,857,811 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12251,867,151 - 251,872,419 (-)NCBI
Celera2234,777,191 - 234,782,459 (-)NCBICelera
Cytogenetic Map2q45NCBI
RABGGTB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38175,786,194 - 75,795,090 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl175,786,197 - 75,795,086 (+)EnsemblGRCh38hg38GRCh38
GRCh37176,251,879 - 76,260,775 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36176,024,474 - 76,033,352 (+)NCBINCBI36Build 36hg18NCBI36
Build 34175,963,906 - 75,972,785NCBI
Celera174,491,796 - 74,500,671 (+)NCBICelera
Cytogenetic Map1p31.1NCBI
HuRef174,381,711 - 74,390,606 (+)NCBIHuRef
CHM1_1176,367,172 - 76,376,066 (+)NCBICHM1_1
T2T-CHM13v2.0175,622,856 - 75,631,751 (+)NCBIT2T-CHM13v2.0
Rabggtb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393153,612,926 - 153,618,603 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3153,612,924 - 153,618,646 (-)EnsemblGRCm39 Ensembl
GRCm383153,907,289 - 153,912,966 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3153,907,287 - 153,913,009 (-)EnsemblGRCm38mm10GRCm38
MGSCv373153,570,253 - 153,575,930 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363153,844,841 - 153,849,445 (-)NCBIMGSCv36mm8
Celera3160,370,948 - 160,376,625 (-)NCBICelera
Cytogenetic Map3H3NCBI
cM Map378.76NCBI
Rabggtb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542317,152,380 - 17,162,310 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542317,155,161 - 17,162,237 (-)NCBIChiLan1.0ChiLan1.0
RABGGTB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21151,097,980 - 151,106,943 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11150,258,522 - 150,267,454 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0175,001,443 - 75,010,421 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1176,973,158 - 76,982,083 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl176,973,158 - 76,982,083 (+)Ensemblpanpan1.1panPan2
RABGGTB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1670,824,822 - 70,834,958 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl670,825,188 - 70,835,238 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha673,489,614 - 73,499,688 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0671,417,955 - 71,428,054 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl671,417,956 - 71,428,066 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1670,913,867 - 70,923,901 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0670,859,305 - 70,869,344 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0671,352,611 - 71,362,696 (-)NCBIUU_Cfam_GSD_1.0
Rabggtb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505887,302,500 - 87,310,667 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365712,812,902 - 2,821,019 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RABGGTB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6137,410,691 - 137,534,233 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16137,525,063 - 137,534,132 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26127,497,462 - 127,506,518 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RABGGTB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12057,398,684 - 57,407,769 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2057,398,327 - 57,407,712 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603360,102,783 - 60,111,881 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rabggtb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474221,168,290 - 21,175,923 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rabggtb
91 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:39
Count of miRNA genes:32
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000065997
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2211744537249053267Rat
631563Hcuc3Hepatic copper content QTL 33.87liver copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)2229059610249053267Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2193452645245889826Rat
2317885Alcrsp28Alcohol response QTL 282.10.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2212828222249053267Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2211744537249053267Rat
7411555Bw132Body weight QTL 1320.001body mass (VT:0001259)body weight gain (CMO:0000420)2223389739249053267Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2211744537249053267Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2211744537249053267Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2214226044247136170Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2211744537249053267Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2200990457245990457Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
9587428Epfw6Epididymal fat weight QTL 67.470.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)2223389739249053267Rat

Markers in Region
RH127932  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22242,844,856 - 242,845,073 (+)MAPPERmRatBN7.2
Rnor_6.02260,110,408 - 260,110,624NCBIRnor6.0
Rnor_5.02278,774,475 - 278,774,691UniSTSRnor5.0
RGSC_v3.42251,852,644 - 251,852,860UniSTSRGSC3.4
Celera2234,777,290 - 234,777,506UniSTS
RH 3.4 Map21629.8UniSTS
Cytogenetic Map2q45UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 35 11 8
Low 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_138708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063281369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010063585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC060536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC078683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L10416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S62097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000065997   ⟹   ENSRNOP00000061541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2242,844,762 - 242,850,951 (-)Ensembl
Rnor_6.0 Ensembl2260,110,309 - 260,115,577 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000099311   ⟹   ENSRNOP00000086870
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2242,844,762 - 242,851,050 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000109806   ⟹   ENSRNOP00000096722
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2242,844,839 - 242,850,204 (-)Ensembl
RefSeq Acc Id: NM_138708   ⟹   NP_619715
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82245,504,586 - 245,510,779 (-)NCBI
mRatBN7.22242,844,758 - 242,850,951 (-)NCBI
Rnor_6.02260,110,309 - 260,115,574 (-)NCBI
Rnor_5.02278,774,376 - 278,779,641 (-)NCBI
RGSC_v3.42251,852,549 - 251,857,811 (-)RGD
Celera2234,777,191 - 234,782,459 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063281366   ⟹   XP_063137436
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82245,504,590 - 245,510,878 (-)NCBI
RefSeq Acc Id: XM_063281367   ⟹   XP_063137437
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82245,504,590 - 245,510,783 (-)NCBI
RefSeq Acc Id: XM_063281368   ⟹   XP_063137438
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82245,504,590 - 245,510,777 (-)NCBI
RefSeq Acc Id: XM_063281369   ⟹   XP_063137439
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82245,504,590 - 245,508,022 (-)NCBI
RefSeq Acc Id: XR_010063585
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82245,505,544 - 245,510,831 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_619715   ⟸   NM_138708
- UniProtKB: Q08603 (UniProtKB/Swiss-Prot),   Q68G48 (UniProtKB/TrEMBL),   A6HWN7 (UniProtKB/TrEMBL),   A0A8I6GFF2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000061541   ⟸   ENSRNOT00000065997
RefSeq Acc Id: ENSRNOP00000086870   ⟸   ENSRNOT00000099311
RefSeq Acc Id: ENSRNOP00000096722   ⟸   ENSRNOT00000109806
RefSeq Acc Id: XP_063137436   ⟸   XM_063281366
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063137437   ⟸   XM_063281367
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063137438   ⟸   XM_063281368
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063137439   ⟸   XM_063281369
- Peptide Label: isoform X4

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q08603-F1-model_v2 AlphaFold Q08603 1-331 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691831
Promoter ID:EPDNEW_R2355
Type:single initiation site
Name:Rabggtb_1
Description:Rab geranylgeranyltransferase, beta subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02260,115,586 - 260,115,646EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3530 AgrOrtholog
BioCyc Gene G2FUF-50774 BioCyc
Ensembl Genes ENSRNOG00000009992 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00055028089 UniProtKB/Swiss-Prot
  ENSRNOG00060001576 UniProtKB/Swiss-Prot
  ENSRNOG00065012661 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000065997.2 UniProtKB/TrEMBL
  ENSRNOT00000099311 ENTREZGENE
  ENSRNOT00000099311.1 UniProtKB/TrEMBL
  ENSRNOT00000109806.1 UniProtKB/TrEMBL
  ENSRNOT00055048677 UniProtKB/Swiss-Prot
  ENSRNOT00060002411 UniProtKB/Swiss-Prot
  ENSRNOT00065020650 UniProtKB/Swiss-Prot
Gene3D-CATH 1.50.10.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6918640 IMAGE-MGC_LOAD
  IMAGE:7135106 IMAGE-MGC_LOAD
InterPro PFTB_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PGGT1B-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ptb1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Terpenoid_cyclase/PrenylTrfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25533 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72651 IMAGE-MGC_LOAD
  MGC:93047 IMAGE-MGC_LOAD
NCBI Gene 25533 ENTREZGENE
PANTHER GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11774 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Prenyltrans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rabggtb PhenoGen
RatGTEx ENSRNOG00000009992 RatGTEx
  ENSRNOG00055028089 RatGTEx
  ENSRNOG00060001576 RatGTEx
  ENSRNOG00065012661 RatGTEx
Superfamily-SCOP SSF48239 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC217759
UniProt A0A8I6GFF2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GLQ7_RAT UniProtKB/TrEMBL
  A6HWN7 ENTREZGENE, UniProtKB/TrEMBL
  A6HWN8_RAT UniProtKB/TrEMBL
  A6HWN9_RAT UniProtKB/TrEMBL
  A6HWP2_RAT UniProtKB/TrEMBL
  A6HWP3_RAT UniProtKB/TrEMBL
  A6HWP4_RAT UniProtKB/TrEMBL
  A6HWP5_RAT UniProtKB/TrEMBL
  F1LSM6_RAT UniProtKB/TrEMBL
  PGTB2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q68G48 ENTREZGENE
  Q6P9Y2_RAT UniProtKB/TrEMBL
UniProt Secondary Q68G48 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-04 Rabggtb  Rab geranylgeranyltransferase subunit beta  Rabggtb  Rab geranylgeranyltransferase, beta subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-24 Rabggtb  Rab geranylgeranyltransferase, beta subunit  Rabggtb  RAB geranylgeranyl transferase, b subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Rabggtb  RAB geranylgeranyl transferase, b subunit    Rab geranylgeranyl transferase componenet, subunit beta  Name updated 1299863 APPROVED
2002-06-10 Rabggtb  Rab geranylgeranyl transferase componenet, subunit beta      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction combines with alpha subunit Rabggta to form Component B of the Rab geranylgeranyl transferase, which combines with an additional Component A for enzyme activity 69952