Sec24a (SEC24 homolog A, COPII coat complex component) - Rat Genome Database

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Gene: Sec24a (SEC24 homolog A, COPII coat complex component) Rattus norvegicus
Analyze
Symbol: Sec24a
Name: SEC24 homolog A, COPII coat complex component
RGD ID: 1309451
Description: Predicted to enable SNARE binding activity and zinc ion binding activity. Predicted to be involved in COPII-coated vesicle cargo loading. Predicted to act upstream of or within cholesterol homeostasis; positive regulation of protein secretion; and regulation of cholesterol transport. Predicted to be located in cytosol and endoplasmic reticulum membrane. Predicted to be part of COPII vesicle coat. Predicted to be active in endoplasmic reticulum exit site. Orthologous to human SEC24A (SEC24 homolog A, COPII coat complex component); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC103689920; LOC287275; protein transport protein Sec24A; SEC24 family member A; SEC24 family, member A; SEC24 family, member A (S. cerevisiae); SEC24 related gene family, member A; SEC24 related gene family, member A (S. cerevisiae) ; uncharacterized LOC103689920
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81036,450,043 - 36,525,303 (-)NCBIGRCr8
mRatBN7.21035,946,901 - 36,024,353 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1035,947,031 - 36,024,353 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1040,642,849 - 40,718,575 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01040,132,834 - 40,208,555 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01035,636,547 - 35,712,284 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01037,138,539 - 37,215,899 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1037,139,806 - 37,215,899 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01036,911,427 - 36,988,825 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01034,817,549 - 34,826,602 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41037,208,603 - 37,283,895 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11037,215,390 - 37,284,473 (-)NCBI
Celera1035,304,430 - 35,379,024 (-)NCBICelera
Cytogenetic Map10q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17499046   PMID:18843296   PMID:20427317   PMID:23580231  


Genomics

Comparative Map Data
Sec24a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81036,450,043 - 36,525,303 (-)NCBIGRCr8
mRatBN7.21035,946,901 - 36,024,353 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1035,947,031 - 36,024,353 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1040,642,849 - 40,718,575 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01040,132,834 - 40,208,555 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01035,636,547 - 35,712,284 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01037,138,539 - 37,215,899 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1037,139,806 - 37,215,899 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01036,911,427 - 36,988,825 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01034,817,549 - 34,826,602 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41037,208,603 - 37,283,895 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11037,215,390 - 37,284,473 (-)NCBI
Celera1035,304,430 - 35,379,024 (-)NCBICelera
Cytogenetic Map10q22NCBI
SEC24A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385134,648,382 - 134,727,909 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5134,648,785 - 134,727,909 (+)EnsemblGRCh38hg38GRCh38
GRCh375133,984,475 - 134,063,599 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365134,012,378 - 134,091,500 (+)NCBINCBI36Build 36hg18NCBI36
Build 345134,012,709 - 134,091,398NCBI
Celera5130,110,657 - 130,189,971 (+)NCBICelera
Cytogenetic Map5q31.1NCBI
HuRef5129,170,647 - 129,249,607 (+)NCBIHuRef
CHM1_15133,417,069 - 133,496,225 (+)NCBICHM1_1
T2T-CHM13v2.05135,172,809 - 135,253,535 (+)NCBIT2T-CHM13v2.0
Sec24a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391151,583,090 - 51,649,172 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1151,583,091 - 51,654,461 (-)EnsemblGRCm39 Ensembl
GRCm381151,692,263 - 51,757,161 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1151,692,264 - 51,763,634 (-)EnsemblGRCm38mm10GRCm38
MGSCv371151,505,765 - 51,570,336 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361151,538,243 - 51,600,008 (-)NCBIMGSCv36mm8
Celera1156,259,252 - 56,323,967 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.28NCBI
Sec24a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554085,803,455 - 5,848,093 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554085,803,438 - 5,850,879 (+)NCBIChiLan1.0ChiLan1.0
SEC24A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24129,945,473 - 130,023,324 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15128,085,052 - 128,162,886 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05130,050,625 - 130,128,212 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15136,197,495 - 136,273,158 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5136,197,746 - 136,273,158 (+)Ensemblpanpan1.1panPan2
SEC24A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11122,749,633 - 22,813,045 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1122,750,046 - 22,810,199 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1121,499,013 - 21,562,145 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01123,555,714 - 23,619,270 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1123,555,703 - 23,619,248 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11122,254,959 - 22,318,573 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01122,121,201 - 22,184,878 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01122,763,524 - 22,826,917 (+)NCBIUU_Cfam_GSD_1.0
Sec24a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213113,607,154 - 113,686,258 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936647612,976 - 688,552 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936647612,640 - 689,963 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEC24A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2136,883,854 - 136,952,178 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12136,833,399 - 136,952,181 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22142,447,631 - 142,565,796 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SEC24A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12337,448,344 - 37,501,745 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603440,396,807 - 40,476,728 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sec24a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473337,620,211 - 37,693,636 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473337,620,326 - 37,693,753 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sec24a
353 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:301
Count of miRNA genes:200
Interacting mature miRNAs:223
Transcripts:ENSRNOT00000006356
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101790711351786432Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101816784163167841Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)101960648364606483Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)101960648364606483Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat
1581497Esta1Estrogen-induced thymic atrophy QTL 1thymus mass (VT:0004954)thymus wet weight (CMO:0000855)102132980561345413Rat
724556Pur2Proteinuria QTL 25.5urine protein amount (VT:0005160)urine protein level (CMO:0000591)102242750090627625Rat
631531Iresp2Immunoglobin response QTL26.3blood immunoglobulin E amount (VT:0002492)serum immunoglobulin E level (CMO:0002101)102291826836400810Rat
61354Pia10Pristane induced arthritis QTL 100.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
631267Cia20Collagen induced arthritis QTL 203.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
61325Aia5Adjuvant induced arthritis QTL 50.01joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1023444813104060283Rat
70224Eae3Experimental allergic encephalomyelitis QTL 34.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)102652195761345413Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
631542Bp82Blood pressure QTL 826.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)102652195798952741Rat
2300171Bmd58Bone mineral density QTL 584.90.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)102694462871944628Rat
10402859Bp381Blood pressure QTL 3810.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
2292441Bp308Blood pressure QTL 308arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102760646872606468Rat
724527Bp148Blood pressure QTL 1480.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)102845313673453136Rat
1600371Mcs21Mammary carcinoma susceptibility QTL 213mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)102887565052200160Rat
1331762Rf40Renal function QTL 403.873kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)102929950464155584Rat
1331791Cm31Cardiac mass QTL 313.84606heart mass (VT:0007028)heart wet weight (CMO:0000069)1029299504107211142Rat
631557Bp136Blood pressure QTL 1360.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)103063205375632053Rat
1576311Pia26Pristane induced arthritis QTL 26joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103122402675632053Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
1576319Cia29Collagen induced arthritis QTL 29joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)103397392178973921Rat
61332Eau3Experimental allergic uveoretinitis QTL 30.004uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)103449055945579777Rat
1354614Hpcl1Hepatic cholesterol level QTL 13.3liver cholesterol amount (VT:0010498)liver cholesterol level (CMO:0001597)103539226751793994Rat
1358897Stresp6Stress response QTL 64.170.022blood norepinephrine amount (VT:0005663)plasma norepinephrine level (CMO:0001010)103539226764155584Rat
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat

Markers in Region
D10Arb18  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21035,987,481 - 35,987,588 (+)MAPPERmRatBN7.2
Rnor_6.01037,179,147 - 37,179,253NCBIRnor6.0
Rnor_5.01036,952,001 - 36,952,107UniSTSRnor5.0
RGSC_v3.41037,246,992 - 37,247,099RGDRGSC3.4
RGSC_v3.41037,246,993 - 37,247,099UniSTSRGSC3.4
RGSC_v3.11037,253,422 - 37,253,529RGD
Celera1035,342,010 - 35,342,116UniSTS
Cytogenetic Map10q22UniSTS
AI180289  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21035,948,889 - 35,949,023 (+)MAPPERmRatBN7.2
Rnor_6.01037,140,528 - 37,140,661NCBIRnor6.0
Rnor_6.01035,046,839 - 35,046,972NCBIRnor6.0
Rnor_5.01036,913,416 - 36,913,549UniSTSRnor5.0
Rnor_5.01034,819,538 - 34,819,671UniSTSRnor5.0
RGSC_v3.41037,208,408 - 37,208,541UniSTSRGSC3.4
Celera1035,304,235 - 35,304,368UniSTS
RH 3.4 Map10387.21UniSTS
Cytogenetic Map10q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 6 29 27 1 27 35 21 26 6
Low 1 37 28 14 18 14 8 11 39 14 15 5 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000006356   ⟹   ENSRNOP00000006356
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1035,949,085 - 36,024,353 (-)Ensembl
Rnor_6.0 Ensembl1037,140,723 - 37,215,899 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000084136
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1035,044,234 - 35,054,225 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000090459
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1035,044,234 - 35,054,225 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000090475   ⟹   ENSRNOP00000069364
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1035,947,031 - 36,018,377 (-)Ensembl
Rnor_6.0 Ensembl1037,139,806 - 37,209,881 (-)Ensembl
RefSeq Acc Id: NM_001105780   ⟹   NP_001099250
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81036,450,043 - 36,525,303 (-)NCBI
mRatBN7.21035,949,085 - 36,024,353 (-)NCBI
Rnor_6.01037,140,723 - 37,215,899 (-)NCBI
Rnor_5.01036,911,427 - 36,988,825 (-)NCBI
RGSC_v3.41037,208,603 - 37,283,895 (-)RGD
Celera1035,304,430 - 35,379,024 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001099250 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM04330 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000006356
  ENSRNOP00000006356.5
  ENSRNOP00000069364.2
Reference Protein Sequences
RefSeq Acc Id: NP_001099250   ⟸   NM_001105780
- UniProtKB: D3ZZA8 (UniProtKB/TrEMBL),   A6HE75 (UniProtKB/TrEMBL),   A0A0G2JV63 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000006356   ⟸   ENSRNOT00000006356
RefSeq Acc Id: ENSRNOP00000069364   ⟸   ENSRNOT00000090475
Protein Domains
Gelsolin-like   Sec23/Sec24 beta-sandwich   Sec23/Sec24 helical   Sec23/Sec24 trunk   Zinc finger Sec23/Sec24-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZZA8-F1-model_v2 AlphaFold D3ZZA8 1-1089 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697165
Promoter ID:EPDNEW_R7689
Type:initiation region
Name:Sec24a_1
Description:SEC24 homolog A, COPII coat complex component
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01037,209,876 - 37,209,936EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309451 AgrOrtholog
BioCyc Gene G2FUF-25189 BioCyc
Ensembl Genes ENSRNOG00000004563 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000056265 Ensembl
Ensembl Transcript ENSRNOT00000006356 ENTREZGENE
  ENSRNOT00000006356.6 UniProtKB/TrEMBL
  ENSRNOT00000090475.2 UniProtKB/TrEMBL
Gene3D-CATH 3.40.20.10 UniProtKB/TrEMBL
  3.40.50.410 UniProtKB/TrEMBL
  beta-sandwich domain of Sec23/24 UniProtKB/TrEMBL
  Sec23/Sec24 helical domain UniProtKB/TrEMBL
  Zn-finger domain of Sec23/24 UniProtKB/TrEMBL
InterPro ADF-H/Gelsolin-like_dom UniProtKB/TrEMBL
  Gelsolin-like_dom_sf UniProtKB/TrEMBL
  Gelsolin_dom UniProtKB/TrEMBL
  Sec23/24_helical_dom UniProtKB/TrEMBL
  Sec23/24_helical_dom_sf UniProtKB/TrEMBL
  Sec23/24_trunk_dom UniProtKB/TrEMBL
  Sec23_24_beta_S UniProtKB/TrEMBL
  Sec24-like_trunk_dom UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/TrEMBL
  Znf_Sec23_Sec24 UniProtKB/TrEMBL
  Znf_Sec23_Sec24_sf UniProtKB/TrEMBL
KEGG Report rno:287275 UniProtKB/TrEMBL
NCBI Gene 287275 ENTREZGENE
PANTHER PROTEIN TRANSPORT PROTEIN SEC24A UniProtKB/TrEMBL
  SEC24-RELATED PROTEIN UniProtKB/TrEMBL
Pfam Gelsolin UniProtKB/TrEMBL
  Sec23_BS UniProtKB/TrEMBL
  Sec23_helical UniProtKB/TrEMBL
  Sec23_trunk UniProtKB/TrEMBL
  zf-Sec23_Sec24 UniProtKB/TrEMBL
PhenoGen Sec24a PhenoGen
RatGTEx ENSRNOG00000004563 RatGTEx
  ENSRNOG00000056265 RatGTEx
Superfamily-SCOP beta-sandwich domain of Sec23/24 UniProtKB/TrEMBL
  Sec23_helical UniProtKB/TrEMBL
  SSF53300 UniProtKB/TrEMBL
  SSF82754 UniProtKB/TrEMBL
  SSF82919 UniProtKB/TrEMBL
UniProt A0A0G2JV63 ENTREZGENE, UniProtKB/TrEMBL
  A6HE75 ENTREZGENE, UniProtKB/TrEMBL
  D3ZZA8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Sec24a  SEC24 homolog A, COPII coat complex component  LOC103689920  uncharacterized LOC103689920  Data merged from RGD:9221572 737654 PROVISIONAL
2015-08-13 Sec24a  SEC24 homolog A, COPII coat complex component  Sec24a  SEC24 family member A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-08-25 LOC103689920  uncharacterized LOC103689920      Symbol and Name status set to provisional 70820 PROVISIONAL
2013-11-11 Sec24a  SEC24 family member A  Sec24a  SEC24 family, member A (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-20 Sec24a  SEC24 family, member A (S. cerevisiae)  Sec24a  SEC24 related gene family, member A (S. cerevisiae)   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Sec24a  SEC24 related gene family, member A (S. cerevisiae)   Sec24a_predicted  SEC24 related gene family, member A (S. cerevisiae) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Sec24a_predicted  SEC24 related gene family, member A (S. cerevisiae) (predicted)      Symbol and Name status set to approved 70820 APPROVED