G2e3 (G2/M-phase specific E3 ubiquitin protein ligase) - Rat Genome Database

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Gene: G2e3 (G2/M-phase specific E3 ubiquitin protein ligase) Rattus norvegicus
Analyze
Symbol: G2e3
Name: G2/M-phase specific E3 ubiquitin protein ligase
RGD ID: 1310263
Description: Predicted to enable ubiquitin protein ligase activity. Predicted to act upstream of or within blastocyst development; negative regulation of intrinsic apoptotic signaling pathway; and protein polyubiquitination. Predicted to be located in Golgi apparatus and cytosol. Predicted to be active in nucleus. Orthologous to human G2E3 (G2/M-phase specific E3 ubiquitin protein ligase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: G2/M phase-specific E3 ubiquitin-protein ligase; G2/M-phase specific E3 ubiquitin ligase; LOC299002; RGD1310263; similar to KIAA1333 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8674,498,801 - 74,530,703 (+)NCBIGRCr8
mRatBN7.2668,763,847 - 68,795,305 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl668,764,185 - 68,793,924 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx669,199,329 - 69,229,045 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0669,505,985 - 69,535,701 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0668,945,463 - 68,975,179 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0672,092,148 - 72,123,878 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl672,092,194 - 72,122,497 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0681,655,773 - 81,687,699 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4671,421,049 - 71,451,405 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1671,424,101 - 71,452,823 (+)NCBI
Celera667,653,726 - 67,683,695 (+)NCBICelera
Cytogenetic Map6q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aflatoxin M1  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
coumestrol  (ISO)
cyclosporin A  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Enterolactone  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
glycidol  (EXP)
gold atom  (ISO)
gold(0)  (ISO)
hydrogen peroxide  (ISO)
inulin  (ISO)
irinotecan  (ISO)
menadione  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
succimer  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:18511420  


Genomics

Comparative Map Data
G2e3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8674,498,801 - 74,530,703 (+)NCBIGRCr8
mRatBN7.2668,763,847 - 68,795,305 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl668,764,185 - 68,793,924 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx669,199,329 - 69,229,045 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0669,505,985 - 69,535,701 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0668,945,463 - 68,975,179 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0672,092,148 - 72,123,878 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl672,092,194 - 72,122,497 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0681,655,773 - 81,687,699 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4671,421,049 - 71,451,405 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1671,424,101 - 71,452,823 (+)NCBI
Celera667,653,726 - 67,683,695 (+)NCBICelera
Cytogenetic Map6q22NCBI
G2E3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381430,559,158 - 30,620,064 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1430,559,158 - 30,620,064 (+)EnsemblGRCh38hg38GRCh38
GRCh371431,028,364 - 31,089,270 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361430,098,128 - 30,158,797 (+)NCBINCBI36Build 36hg18NCBI36
Build 341430,098,127 - 30,158,797NCBI
Celera1410,894,160 - 10,954,826 (+)NCBICelera
Cytogenetic Map14q12NCBI
HuRef1411,145,937 - 11,206,602 (+)NCBIHuRef
CHM1_11431,027,850 - 31,088,578 (+)NCBICHM1_1
T2T-CHM13v2.01424,756,977 - 24,817,883 (+)NCBIT2T-CHM13v2.0
G2e3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391251,395,013 - 51,423,769 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1251,394,844 - 51,423,769 (+)EnsemblGRCm39 Ensembl
GRCm381251,348,230 - 51,376,986 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1251,348,061 - 51,376,986 (+)EnsemblGRCm38mm10GRCm38
MGSCv371252,449,217 - 52,477,973 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361252,269,977 - 52,295,391 (+)NCBIMGSCv36mm8
Celera1252,640,648 - 52,669,412 (+)NCBICelera
Cytogenetic Map12B3NCBI
cM Map1222.11NCBI
G2e3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540929,908,148 - 29,945,497 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540929,908,075 - 29,965,331 (-)NCBIChiLan1.0ChiLan1.0
G2E3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21531,890,589 - 31,951,039 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11431,105,788 - 31,167,541 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01411,338,212 - 11,398,545 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11429,482,966 - 29,539,529 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1429,484,584 - 29,539,430 (+)Ensemblpanpan1.1panPan2
G2E3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.189,914,276 - 9,968,798 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl89,914,008 - 9,965,623 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha89,840,612 - 9,892,078 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0810,015,322 - 10,066,847 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl810,015,374 - 10,069,892 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.189,694,186 - 9,748,718 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.089,775,352 - 9,829,972 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0810,051,563 - 10,106,095 (+)NCBIUU_Cfam_GSD_1.0
G2e3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864041,845,996 - 41,903,754 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364945,352,238 - 5,409,739 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364945,352,126 - 5,409,648 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
G2E3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl768,852,777 - 68,916,992 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1768,854,410 - 68,917,070 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2773,481,201 - 73,541,806 (-)NCBISscrofa10.2Sscrofa10.2susScr3
G2e3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248201,715,455 - 1,774,525 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248201,717,602 - 1,775,175 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in G2e3
201 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:600
Count of miRNA genes:268
Interacting mature miRNAs:342
Transcripts:ENSRNOT00000005670
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
1331779Rf38Renal function QTL 382.876kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)63207442872227641Rat
6893340Cm77Cardiac mass QTL 770.260.57heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)63330954981132889Rat
1300143Rf14Renal function QTL 142.92renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)63443413777102317Rat
1354632Scl29Serum cholesterol level QTL 293.74blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)63509870971636405Rat
634307Bp141Blood pressure QTL 1414arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)63523041780230417Rat
9590290Uminl2Urine mineral level QTL 23.960.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)63878398983783989Rat
9590306Scort18Serum corticosterone level QTL 182.880.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
9590140Scort4Serum corticosterone level QTL 414.490.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)63878398983783989Rat
634330Pia16Pristane induced arthritis QTL 163.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)645790088104200226Rat
4889848Pur25Proteinuria QTL 25140.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)65672856290198260Rat
6893332Cm74Cardiac mass QTL 740.40.64heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)657730540104085867Rat
1558641Cm47Cardiac mass QTL 472.90.001heart mass (VT:0007028)heart wet weight (CMO:0000069)657730540104085867Rat
70176Mcsm1Mammary carcinoma susceptibility modifier QTL 1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)658632962103632962Rat
12801471Schws9Schwannoma susceptibility QTL 9nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)661747639106747639Rat
2293088Iddm28Insulin dependent diabetes mellitus QTL 285.21blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)66304056271636266Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat

Markers in Region
BI303408  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2668,793,659 - 68,793,844 (+)MAPPERmRatBN7.2
Rnor_6.0672,122,233 - 72,122,417NCBIRnor6.0
Rnor_5.0681,686,056 - 81,686,240UniSTSRnor5.0
RGSC_v3.4671,451,141 - 71,451,325UniSTSRGSC3.4
Celera667,683,431 - 67,683,615UniSTS
RH 3.4 Map6503.2UniSTS
Cytogenetic Map6q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 24 26 18 17 18 57 21 41 6
Low 2 18 31 23 2 23 8 10 17 14 5 8
Below cutoff 1 1

Sequence


RefSeq Acc Id: ENSRNOT00000005670   ⟹   ENSRNOP00000005670
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl668,764,185 - 68,793,924 (+)Ensembl
Rnor_6.0 Ensembl672,092,194 - 72,122,497 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094417   ⟹   ENSRNOP00000079200
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl668,764,185 - 68,793,924 (+)Ensembl
RefSeq Acc Id: NM_001106726   ⟹   NP_001100196
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8674,499,586 - 74,529,322 (+)NCBI
mRatBN7.2668,764,185 - 68,793,924 (+)NCBI
Rnor_6.0672,092,194 - 72,122,497 (+)NCBI
Rnor_5.0681,655,773 - 81,687,699 (+)NCBI
RGSC_v3.4671,421,049 - 71,451,405 (+)RGD
Celera667,653,726 - 67,683,695 (+)RGD
Sequence:
RefSeq Acc Id: XM_006240078   ⟹   XP_006240140
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8674,498,801 - 74,530,703 (+)NCBI
mRatBN7.2668,763,848 - 68,795,305 (+)NCBI
Rnor_6.0672,092,148 - 72,123,878 (+)NCBI
Rnor_5.0681,655,773 - 81,687,699 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006240079   ⟹   XP_006240141
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8674,498,801 - 74,530,703 (+)NCBI
mRatBN7.2668,764,331 - 68,795,305 (+)NCBI
Rnor_6.0672,095,602 - 72,123,878 (+)NCBI
Rnor_5.0681,655,773 - 81,687,699 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594082   ⟹   XP_017449571
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8674,498,801 - 74,530,703 (+)NCBI
mRatBN7.2668,763,847 - 68,795,305 (+)NCBI
Rnor_6.0672,092,148 - 72,123,878 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017594083   ⟹   XP_017449572
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8674,498,801 - 74,530,703 (+)NCBI
mRatBN7.2668,764,327 - 68,795,305 (+)NCBI
Rnor_6.0672,095,602 - 72,123,878 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063261666   ⟹   XP_063117736
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8674,498,801 - 74,530,703 (+)NCBI
RefSeq Acc Id: XM_063261667   ⟹   XP_063117737
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8674,498,801 - 74,530,703 (+)NCBI
RefSeq Acc Id: NP_001100196   ⟸   NM_001106726
- UniProtKB: D3ZC11 (UniProtKB/TrEMBL),   A6HBG8 (UniProtKB/TrEMBL),   A0A8I5ZML5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240140   ⟸   XM_006240078
- Peptide Label: isoform X1
- UniProtKB: D3ZC11 (UniProtKB/TrEMBL),   A6HBG8 (UniProtKB/TrEMBL),   A0A8I5ZML5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240141   ⟸   XM_006240079
- Peptide Label: isoform X1
- UniProtKB: D3ZC11 (UniProtKB/TrEMBL),   A6HBG8 (UniProtKB/TrEMBL),   A0A8I5ZML5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449571   ⟸   XM_017594082
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZML5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017449572   ⟸   XM_017594083
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZML5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000005670   ⟸   ENSRNOT00000005670
RefSeq Acc Id: ENSRNOP00000079200   ⟸   ENSRNOT00000094417
RefSeq Acc Id: XP_063117736   ⟸   XM_063261666
- Peptide Label: isoform X1
- UniProtKB: A6HBG8 (UniProtKB/TrEMBL),   D3ZC11 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063117737   ⟸   XM_063261667
- Peptide Label: isoform X2
Protein Domains
HECT   PHD-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZC11-F1-model_v2 AlphaFold D3ZC11 1-717 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694582
Promoter ID:EPDNEW_R5107
Type:initiation region
Name:G2e3_1
Description:G2/M-phase specific E3 ubiquitin protein ligase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0672,092,173 - 72,092,233EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310263 AgrOrtholog
BioCyc Gene G2FUF-37597 BioCyc
Ensembl Genes ENSRNOG00000004232 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005670 ENTREZGENE
  ENSRNOT00000005670.8 UniProtKB/TrEMBL
  ENSRNOT00000094417.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  Hect, E3 ligase catalytic domain UniProtKB/TrEMBL
  Hect, E3 ligase catalytic domains UniProtKB/TrEMBL
InterPro EPHD UniProtKB/TrEMBL
  HECT UniProtKB/TrEMBL
  Hect_E3_ubiquitin_ligase UniProtKB/TrEMBL
  PHF7/G2E3_ePHD UniProtKB/TrEMBL
  PHF7/G2E3_PHD UniProtKB/TrEMBL
  Zinc_finger_PHD-type_CS UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report rno:299002 UniProtKB/TrEMBL
NCBI Gene 299002 ENTREZGENE
PANTHER G2/M PHASE-SPECIFIC E3 UBIQUITIN-PROTEIN LIGASE UniProtKB/TrEMBL
  PHD FINGER PROTEIN UniProtKB/TrEMBL
Pfam HECT UniProtKB/TrEMBL
  zf-HC5HC2H UniProtKB/TrEMBL
PhenoGen G2e3 PhenoGen
PROSITE EPHD UniProtKB/TrEMBL
  HECT UniProtKB/TrEMBL
  ZF_PHD_1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004232 RatGTEx
SMART HECTc UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
Superfamily-SCOP FYVE_PHD_ZnF UniProtKB/TrEMBL
  HECT UniProtKB/TrEMBL
UniProt A0A8I5ZML5 ENTREZGENE, UniProtKB/TrEMBL
  A6HBG8 ENTREZGENE, UniProtKB/TrEMBL
  D3ZC11 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 G2e3  G2/M-phase specific E3 ubiquitin protein ligase  G2e3  G2/M-phase specific E3 ubiquitin ligase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-06-12 G2e3  G2/M-phase specific E3 ubiquitin ligase  RGD1310263  similar to KIAA1333 protein   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1310263  similar to KIAA1333 protein   RGD1310263_predicted  similar to KIAA1333 protein (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1310263_predicted  similar to KIAA1333 protein (predicted)  LOC299002_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC299002_predicted  similar to KIAA1333 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL