The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A glucocorticoid steroid having a highly oxygenated pregna-1,4-diene structure. It is used mainly in the treatment of asthma and non-infectious rhinitis and for treatment and prevention of nasal polyposis.
Budesonide inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] Budesonide results in decreased activity of ABCB11 protein
Budesonide binds to and results in decreased activity of AR protein; Budesonide inhibits the reaction [Metribolone results in increased activity of AR protein]
Budesonide results in decreased expression of CCL2 protein Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CCL2 mRNA]; Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CCL2 protein]
Budesonide inhibits the reaction [TNF protein results in increased secretion of CCL5 mRNA]; Budesonide inhibits the reaction [TNF protein results in increased secretion of CCL5 protein]
Budesonide inhibits the reaction [vinyl carbamate results in decreased expression of CDKN1A protein] Budesonide results in increased expression of CDKN1A mRNA
Budesonide inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein] Budesonide results in decreased secretion of CSF2 protein Budesonide results in increased activity of CSF2 protein
Budesonide results in decreased expression of CYP3A2 mRNA [Budesonide results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA Budesonide results in increased expression of CYP3A4 mRNA
Budesonide results in increased expression of CYP3A9 mRNA Budesonide results in increased expression of CYP3A5 mRNA Ketoconazole inhibits the reaction [Budesonide results in increased expression of CYP3A5 mRNA]; Mifepristone inhibits the reaction [Budesonide results in increased expression of CYP3A5 mRNA]
Budesonide results in decreased secretion of IFNG protein [zafirlukast co-treated with Prednisone co-treated with Budesonide] inhibits the reaction [Antigens results in increased secretion of IFNG protein]
Budesonide inhibits the reaction [IL13 protein results in increased expression of CCL11 protein]; Budesonide inhibits the reaction [IL13 protein results in increased expression of IL6 mRNA]; Budesonide inhibits the reaction [IL13 protein results in increased expression of IL6 protein] Budesonide results in increased activity of IL13 protein
Budesonide inhibits the reaction [Ozone results in increased expression of IL17A protein]; Progesterone promotes the reaction [Budesonide inhibits the reaction [Ozone results in increased expression of IL17A protein]]
Budesonide results in decreased secretion of IL1B protein Budesonide inhibits the reaction [[TNF protein co-treated with IL1B protein] results in decreased susceptibility to Formoterol Fumarate]; Budesonide inhibits the reaction [[TNF protein co-treated with IL1B protein] results in decreased susceptibility to Salmeterol Xinafoate]; Budesonide inhibits the reaction [[TNF protein co-treated with IL1B protein] results in decreased susceptibility to Terbutaline]; Budesonide inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of PTGS2 mRNA]; Budesonide inhibits the reaction [Ozone results in increased expression of IL1B protein] Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL1B mRNA]; Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL1B protein] Budesonide inhibits the reaction [IL1B protein results in increased acetylation of H4C16 protein]; Budesonide inhibits the reaction [IL1B protein results in increased expression of SELE mRNA]; Budesonide inhibits the reaction [IL1B protein results in increased secretion of CSF2 protein]; Budesonide inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; Hydrogen Peroxide inhibits the reaction [Budesonide inhibits the reaction [IL1B protein results in increased acetylation of H4C16 protein]]; Theophylline inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Budesonide inhibits the reaction [IL1B protein results in increased acetylation of H4C16 protein]]]
Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]; Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 protein] Budesonide inhibits the reaction [IL13 protein results in increased expression of IL6 mRNA]; Budesonide inhibits the reaction [IL13 protein results in increased expression of IL6 protein] Budesonide inhibits the reaction [Ozone results in increased expression of IL6 protein]; Progesterone promotes the reaction [Budesonide inhibits the reaction [Ozone results in increased expression of IL6 protein]]
Budesonide inhibits the reaction [Colforsin promotes the reaction [Glucose results in increased secretion of INS1 protein]]; Budesonide inhibits the reaction [Glucose results in increased secretion of INS1 protein]
Budesonide inhibits the reaction [methylcholine results in increased secretion of LTF protein] Budesonide results in decreased secretion of LTF protein
Budesonide inhibits the reaction [Cadmium Chloride results in increased activity of MMP9 protein]; Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of MMP9 mRNA]; Budesonide promotes the reaction [Formoterol Fumarate inhibits the reaction [Cadmium Chloride results in increased activity of MMP9 protein]]; Formoterol Fumarate promotes the reaction [Budesonide inhibits the reaction [Cadmium Chloride results in increased activity of MMP9 protein]]
Budesonide results in decreased expression of NOS2 mRNA Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]
Budesonide results in increased expression of NR1I2 mRNA Budesonide results in increased activity of NR1I2 protein [Budesonide results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA
2,2',3,5',6-pentachlorobiphenyl inhibits the reaction [Budesonide results in increased activity of NR3C1 protein]; 2,3',4,4',5-pentachlorobiphenyl inhibits the reaction [Budesonide results in increased activity of NR3C1 protein]; 2,4,2',4'-tetrachlorobiphenyl inhibits the reaction [Budesonide results in increased activity of NR3C1 protein]; 2,4,4'-trichlorobiphenyl inhibits the reaction [Budesonide results in increased activity of NR3C1 protein]; 2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Budesonide results in increased activity of NR3C1 protein]; 2,4,5,2',5'-pentachlorobiphenyl inhibits the reaction [Budesonide results in increased activity of NR3C1 protein]; 2,5,2',5'-tetrachlorobiphenyl inhibits the reaction [Budesonide results in increased activity of NR3C1 protein]; Budesonide affects the reaction [Terbutaline results in increased expression of NR3C1 mRNA] Budesonide results in decreased expression of NR3C1 mRNA Budesonide binds to NR3C1 protein [Budesonide binds to NR3C1 protein] which results in increased expression of SLC51A mRNA; [Budesonide binds to NR3C1 protein] which results in increased expression of SLC51B mRNA
[Budesonide co-treated with Glucose] binds to PPARA protein; Budesonide inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]]
Budesonide inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of PTGS2 mRNA] Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]
Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of SELE mRNA] Budesonide inhibits the reaction [IL1B protein results in increased expression of SELE mRNA]
Budesonide inhibits the reaction [SLC22A3 protein results in increased uptake of Formoterol Fumarate]; SLC22A3 protein results in increased susceptibility to [Budesonide results in decreased transport of Formoterol Fumarate]
Budesonide inhibits the reaction [SLCO1B3 protein results in increased uptake of Mesalamine]; Budesonide inhibits the reaction [SLCO1B3 protein results in increased uptake of Sulfobromophthalein]
Budesonide inhibits the reaction [SLCO2B1 protein results in increased uptake of Mesalamine]; Budesonide inhibits the reaction [SLCO2B1 protein results in increased uptake of Sulfobromophthalein]
Budesonide promotes the reaction [LG 100268 promotes the reaction [T0901317 results in increased expression of STAR mRNA]]; Budesonide promotes the reaction [LG 100268 promotes the reaction [T0901317 results in increased expression of STAR protein]]; Budesonide promotes the reaction [T0901317 promotes the reaction [LG 100268 results in increased expression of STAR protein]]
Budesonide results in decreased expression of TNF protein Budesonide results in decreased secretion of TNF protein Budesonide inhibits the reaction [[TNF protein co-treated with IL1B protein] results in decreased susceptibility to Formoterol Fumarate]; Budesonide inhibits the reaction [[TNF protein co-treated with IL1B protein] results in decreased susceptibility to Salmeterol Xinafoate]; Budesonide inhibits the reaction [[TNF protein co-treated with IL1B protein] results in decreased susceptibility to Terbutaline]; Budesonide inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of PTGS2 mRNA]; Budesonide inhibits the reaction [Ozone results in increased expression of TNF protein] Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]; Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein] Budesonide inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Budesonide inhibits the reaction [TNF protein results in increased secretion of CCL5 mRNA]; Budesonide inhibits the reaction [TNF protein results in increased secretion of CCL5 protein]; Budesonide inhibits the reaction [TNF protein results in increased secretion of CXCL8 mRNA]; Budesonide inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein]
Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of VCAM1 mRNA] Budesonide inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]
Budesonide results in decreased expression of VEGFA protein Budesonide inhibits the reaction [Benzo(a)pyrene results in increased expression of VEGFA mRNA]; Budesonide inhibits the reaction [Benzo(a)pyrene results in increased expression of VEGFA protein]
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