Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:cellular response to insulin stimulus
go back to main search page
Accession:GO:0032869 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.


show annotations for term's descendants           Sort by:
cellular response to insulin stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL5 acyl-CoA synthetase long chain family member 5 ISO RGD PMID:16198472 RGD:2312808 NCBI chr28:23,437,838...23,478,763
Ensembl chr28:23,440,387...23,478,762 		JBrowse link
G ACSL6 acyl-CoA synthetase long chain family member 6 ISO RGD PMID:16428347 RGD:1599808 NCBI chr11:20,226,877...20,284,919
Ensembl chr11:20,227,268...20,285,631 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing acts_upstream_of_or_within
involved_in		 ISO
ISS		 (PMID:17693256) RGD
MGI
UniProt		 PMID:17693256 PMID:21401303 GO_REF:0000024 RGD:5686346 NCBI chr34:19,398,310...19,410,519
Ensembl chr34:19,354,825...19,409,844 		JBrowse link
G AHSG alpha 2-HS glycoprotein ISO RGD PMID:7513166 RGD:1626076 NCBI chr34:19,221,034...19,228,866
Ensembl chr34:19,221,107...19,228,716 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 PMID:17715136
(PMID:17715136)		 MGI
RGD
Ensembl		 PMID:9005851 PMID:9065430 PMID:17715136 GO_REF:0000107 RGD:407420264 RGD:407572520 RGD:8553574 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193 		JBrowse link
G AKT2 AKT serine/threonine kinase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 PMID:17715136 MGI
Ensembl		 PMID:17715136 GO_REF:0000107 RGD:8553574 NCBI chr 1:113,359,038...113,407,119
Ensembl chr 1:113,359,575...113,407,131 		JBrowse link
G AKT3 AKT serine/threonine kinase 3 acts_upstream_of_or_within ISO PMID:17715136 MGI PMID:17715136 RGD:8553574 NCBI chr 7:34,633,064...34,931,112
Ensembl chr 7:34,636,124...34,931,112 		JBrowse link
G ALAS1 5'-aminolevulinate synthase 1 ISO RGD PMID:11716532 RGD:4144187 NCBI chr20:37,552,813...37,566,417
Ensembl chr20:37,552,814...37,566,638 		JBrowse link
G ALDOB aldolase, fructose-bisphosphate B ISO also dexamethasone, glucagon RGD PMID:9473304 RGD:1599069 NCBI chr11:58,150,621...58,166,266
Ensembl chr11:58,150,967...58,176,319 		JBrowse link
G APOBEC1 apolipoprotein B mRNA editing enzyme catalytic subunit 1 ISO RGD PMID:9667237 RGD:1626288 NCBI chr27:37,102,728...37,114,084
Ensembl chr27:37,103,016...37,114,556 		JBrowse link
G APRT adenine phosphoribosyltransferase ISO RGD PMID:2185659 RGD:2316798 NCBI chr 5:64,563,154...64,565,537
Ensembl chr 5:64,563,192...64,565,445 		JBrowse link
G AZGP1 alpha-2-glycoprotein 1, zinc-binding ISO RGD PMID:30950934 RGD:153350153 NCBI chr 6:9,622,991...9,629,154
Ensembl chr 6:9,622,992...9,629,154 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein involved_in ISS UniProt GO_REF:0000024 NCBI chr 7:41,630,092...41,630,976
Ensembl chr 7:41,630,098...41,665,791 		JBrowse link
G CA3 carbonic anhydrase 3 ISO RGD PMID:15500001 RGD:408427359 NCBI chr29:31,935,192...31,945,585
Ensembl chr29:31,935,172...31,980,579 		JBrowse link
G CAPN10 calpain 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:50,555,402...50,566,132
Ensembl chr25:50,555,425...50,566,135 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO RGD PMID:17180354 RGD:8549642 NCBI chr 9:39,008,187...39,009,932 JBrowse link
G CCND2 cyclin D2 ISO RGD PMID:16210359 RGD:1582339 NCBI chr27:40,563,306...40,593,362
Ensembl chr27:40,564,921...40,594,255 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) ISO RGD PMID:19273501 RGD:2307221 NCBI chr18:20,299,808...20,375,856
Ensembl chr18:20,339,050...20,372,639 		JBrowse link
G CDK2 cyclin dependent kinase 2 ISO RGD PMID:15994754 RGD:2293572 NCBI chr10:300,863...306,546
Ensembl chr10:300,903...305,438 		JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO PMID:7626603 UniProt PMID:7626603 RGD:11059572 NCBI chr 1:111,902,429...111,919,191
Ensembl chr 1:111,745,413...111,917,830 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator ISO RGD PMID:18292530 RGD:11341712 NCBI chr37:10,268,407...10,307,803
Ensembl chr37:10,268,582...10,345,095 		JBrowse link
G CLASP2 cytoplasmic linker associated protein 2 ISO RGD PMID:22992739 RGD:28912745 NCBI chr23:3,261,778...3,423,698
Ensembl chr23:3,246,522...3,421,716 		JBrowse link
G CPEB1 cytoplasmic polyadenylation element binding protein 1 involved_in ISO (PMID:18752464) UniProt PMID:18752464 NCBI chr 3:54,405,140...54,499,614
Ensembl chr 3:54,405,717...54,500,221 		JBrowse link
G CPEB2 cytoplasmic polyadenylation element binding protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:65,200,175...65,277,353
Ensembl chr 3:65,203,759...65,267,967 		JBrowse link
G CYFIP1 cytoplasmic FMR1 interacting protein 1 ISO RGD PMID:16260607 RGD:11557987 NCBI chr 3:32,096,471...32,170,107
Ensembl chr 3:32,097,037...32,187,781 		JBrowse link
G DENND4C DENN domain containing 4C involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:39,035,241...39,161,135
Ensembl chr11:39,072,944...39,159,611 		JBrowse link
G DLC1 DLC1 Rho GTPase activating protein ISO RGD PMID:16338927 RGD:2304073 NCBI chr16:36,531,754...36,943,033
Ensembl chr16:36,531,754...36,943,033 		JBrowse link
G DPEP1 dipeptidase 1 involved_in ISO (PMID:17615681) UniProt PMID:17615681 NCBI chr 5:63,909,034...63,923,309
Ensembl chr 5:63,909,042...63,923,492 		JBrowse link
G DRD1 dopamine receptor D1 ISO RGD PMID:12707290 RGD:2302121 NCBI chr 4:37,550,454...37,554,641
Ensembl chr 4:37,549,708...37,553,287 		JBrowse link
G EEF2K eukaryotic elongation factor 2 kinase ISO RGD PMID:9841860 RGD:10401230 NCBI chr 6:23,368,296...23,433,853
Ensembl chr 6:23,371,546...23,433,929 		JBrowse link
G EGR1 early growth response 1 ISO RGD PMID:12970165 RGD:1601014 NCBI chr11:26,046,195...26,049,806
Ensembl chr11:26,046,228...26,048,575 		JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (PMID:17849011), (PMID:7830796) BHF-UCL PMID:7830796 PMID:17849011 NCBI chr 1:251,985...322,081
Ensembl chr 1:252,103...322,718 		JBrowse link
G EPRS1 glutamyl-prolyl-tRNA synthetase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:14,754,628...14,823,626
Ensembl chr38:14,754,632...14,823,621 		JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 ISO RGD PMID:9389501 RGD:2289971 NCBI chr10:406,856...424,746
Ensembl chr10:406,633...424,264 		JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 ISO RGD PMID:15358516 RGD:9685544 NCBI chr 5:61,621,964...61,636,152
Ensembl chr 5:61,622,550...61,636,148 		JBrowse link
G FBP1 fructose-bisphosphatase 1 ISO RGD PMID:2847161 PMID:9530152 RGD:1298915 RGD:151665787 NCBI chr 1:72,099,886...72,125,266
Ensembl chr 1:72,099,881...72,125,224 		JBrowse link
G FOXO1 forkhead box O1 involved_in ISO (PMID:17681146) UniProt PMID:17681146 NCBI chr25:603,433...706,961
Ensembl chr25:603,543...702,825 		JBrowse link
G G6PC1 glucose-6-phosphatase catalytic subunit 1 ISO RGD PMID:19579180 RGD:14695551 NCBI chr 9:20,132,973...20,143,642
Ensembl chr 9:20,132,978...20,143,642 		JBrowse link
G GCK glucokinase involved_in ISO PMID:17470517 BHF-UCL PMID:17470517 RGD:8554539
G GCLC glutamate-cysteine ligase catalytic subunit ISO RGD PMID:15169830 RGD:10402381 NCBI chr12:20,999,815...21,047,779
Ensembl chr12:21,000,792...21,047,779 		JBrowse link
G GFPT1 glutamine--fructose-6-phosphate transaminase 1 ISO RGD PMID:10604279 RGD:1625427 NCBI chr10:68,067,817...68,125,001
Ensembl chr10:68,073,062...68,125,007 		JBrowse link
G GH1 growth hormone involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:11,832,265...11,834,123
Ensembl chr 9:11,832,265...11,834,123 		JBrowse link
G GHR growth hormone receptor ISO RGD PMID:18040895 RGD:2307371 NCBI chr 4:67,021,821...67,245,499
Ensembl chr 4:67,022,252...67,290,473 		JBrowse link
G GHRHR growth hormone releasing hormone receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16513828) Ensembl
MGI		 PMID:16513828 GO_REF:0000107 NCBI chr14:43,626,862...43,638,737
Ensembl chr14:43,626,845...43,638,753 		JBrowse link
G GHSR growth hormone secretagogue receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16513828) Ensembl
MGI		 PMID:16513828 GO_REF:0000107 NCBI chr34:36,691,132...36,694,304
Ensembl chr34:36,690,224...36,694,312 		JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:12,352,658...12,377,960
Ensembl chr28:12,352,659...12,414,579 		JBrowse link
G GPAM glycerol-3-phosphate acyltransferase, mitochondrial ISO RGD PMID:18167308 RGD:2313661 NCBI chr28:23,261,673...23,323,985
Ensembl chr28:23,258,428...23,298,017 		JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:22,495,001...22,556,264
Ensembl chr35:22,495,073...22,554,105 		JBrowse link
G GPT glutamic--pyruvic transaminase ISO RGD PMID:25865565 RGD:11342811 NCBI chr13:37,923,757...37,927,843
Ensembl chr13:37,924,422...37,926,156 		JBrowse link
G GPT2 glutamic--pyruvic transaminase 2 ISO RGD PMID:25865565 RGD:11342811 NCBI chr15:8,238,295...8,250,789 JBrowse link
G GRB14 growth factor receptor bound protein 14 involved_in ISO PMID:14623073 CAFA PMID:14623073 RGD:12793049 NCBI chr36:9,711,885...9,843,266
Ensembl chr36:9,712,142...9,721,769 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:112,129,116...112,138,714
Ensembl chr 1:112,103,825...112,138,559 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 ISO RGD PMID:1908848 RGD:2317845 NCBI chr18:49,905,161...49,908,182
Ensembl chr18:49,905,161...49,908,182 		JBrowse link
G H2AZ1 H2A.Z variant histone 1 ISO RGD PMID:24471919 RGD:9588479 NCBI chr32:21,889,890...21,892,165
Ensembl chr32:21,889,877...21,892,102 		JBrowse link
G HDAC9 histone deacetylase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:32,469,349...33,310,439
Ensembl chr14:32,588,414...33,304,387 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO RGD PMID:16506055 RGD:1626318 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692 		JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 ISO RGD PMID:12027802 RGD:1599891 NCBI chr17:56,679,942...56,698,521
Ensembl chr17:56,680,301...56,698,419 		JBrowse link
G HNRNPK heterogeneous nuclear ribonucleoprotein K ISO RGD PMID:15485813 PMID:16837467 PMID:21291866 RGD:10002778 RGD:10002795 RGD:10058978 NCBI chr 1:75,499,334...75,511,525
Ensembl chr 1:75,499,393...75,511,425 		JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 ISO RGD PMID:2185659 RGD:2316798 NCBI chr  X:105,115,732...105,153,702
Ensembl chr  X:105,115,732...105,153,702 		JBrowse link
G IGF1 insulin like growth factor 1 ISO RGD PMID:20013160 RGD:10046039 NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794 		JBrowse link
G IGF1R insulin like growth factor 1 receptor acts_upstream_of_or_within ISO (PMID:21677284) RGD
MGI		 PMID:20013160 PMID:21677284 RGD:10046039 NCBI chr 3:41,795,337...42,096,255
Ensembl chr 3:41,794,623...42,090,387 		JBrowse link
G INHBB inhibin subunit beta B involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:29,765,697...29,768,485
Ensembl chr19:29,767,682...29,768,077 		JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:45,660,445...45,680,407
Ensembl chr 9:45,660,446...45,680,363 		JBrowse link
G INSIG1 insulin induced gene 1 involved_in ISO
IBA		 RGD
GO_Central		 PMID:19299314 GO_REF:0000033 RGD:2308854 NCBI chr16:18,260,456...18,271,855
Ensembl chr16:18,259,935...18,271,378 		JBrowse link
G INSIG2 insulin induced gene 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:31,796,984...31,811,556
Ensembl chr19:31,791,710...31,811,386 		JBrowse link
G INSR insulin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:52,017,261...52,136,061
Ensembl chr20:52,021,887...52,136,046 		JBrowse link
G IRS1 insulin receptor substrate 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11375348) Ensembl
MGI		 PMID:11375348 GO_REF:0000107 NCBI chr25:39,624,554...39,687,991 JBrowse link
G IRS2 insulin receptor substrate 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11375348) RGD
MGI
Ensembl		 PMID:11375348 PMID:22912850 GO_REF:0000107 RGD:7257698 NCBI chr22:58,197,016...58,229,026
Ensembl chr22:58,223,387...58,227,535 		JBrowse link
G KAT2B lysine acetyltransferase 2B involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:23,166,722...23,242,447
Ensembl chr23:23,168,600...23,233,478 		JBrowse link
G LEP leptin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29519872) Ensembl
MGI		 PMID:29519872 GO_REF:0000107 NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395 		JBrowse link
G LPIN1 lipin 1 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:10438476) RGD
GO_Central
MGI		 PMID:10438476 PMID:11792863 GO_REF:0000033 RGD:1641823 NCBI chr17:8,348,860...8,480,447
Ensembl chr17:8,348,886...8,478,863 		JBrowse link
G LPIN2 lipin 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:69,583,386...69,664,226
Ensembl chr 7:69,580,736...69,673,899 		JBrowse link
G LPIN3 lipin 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr24:29,343,658...29,360,472
Ensembl chr24:29,347,627...29,399,854 		JBrowse link
G MAPKAP1 MAPK associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:57,447,115...57,699,979
Ensembl chr 9:57,446,832...57,699,950 		JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:84,818,893...84,939,283
Ensembl chr 2:84,787,708...84,939,114 		JBrowse link
G MUC4 mucin 4, cell surface associated ISO RGD PMID:10980611 RGD:2303745 NCBI chr33:29,061,372...29,084,938
Ensembl chr33:29,063,096...29,111,802 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor ISO RGD PMID:2200903 RGD:10059628 NCBI chr13:25,200,772...25,205,309
Ensembl chr13:25,200,577...25,205,309 		JBrowse link
G MYO5A myosin VA involved_in ISO (PMID:22908308) UniProt PMID:22908308 NCBI chr30:17,990,521...18,122,160
Ensembl chr30:17,888,419...18,213,061 		JBrowse link
G NOS3 nitric oxide synthase 3 ISO RGD PMID:29055722 RGD:13450916 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase ISO RGD PMID:15561949 RGD:9590198 NCBI chr  X:55,821,227...55,857,597
Ensembl chr  X:55,821,234...55,855,502 		JBrowse link
G OTOP1 otopetrin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:69,639,550...69,665,051
Ensembl chr 3:69,640,492...69,649,201 		JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 ISO RGD PMID:8702668 RGD:2299859 NCBI chr21:21,341,530...21,409,535
Ensembl chr21:21,265,484...21,408,416 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:38,503,072...38,542,556
Ensembl chr 7:38,503,067...38,542,127 		JBrowse link
G PAX6 paired box 6 ISO RGD PMID:18189319 RGD:8552378
G PCK1 phosphoenolpyruvate carboxykinase 1 involved_in IEA
IBA
ISO		 Ensembl
GO_Central
RGD		 PMID:9530152 PMID:21519922 GO_REF:0000033 GO_REF:0000107 RGD:10428394 RGD:151665787 NCBI chr24:42,538,858...42,544,200
Ensembl chr24:42,538,882...42,544,198 		JBrowse link
G PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:4,099,016...4,107,870
Ensembl chr 8:4,098,671...4,107,865 		JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 involved_in ISO PMID:16407292
(PMID:16407292)		 HGNC-UCL PMID:16407292 RGD:8553473 NCBI chr 5:54,197,211...54,210,724 JBrowse link
G PDE3B phosphodiesterase 3B involved_in ISO (PMID:10454575) BHF-UCL PMID:10454575 NCBI chr21:37,364,940...37,532,152
Ensembl chr21:37,364,623...37,530,597 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,426,464...38,506,520
Ensembl chr 6:38,431,600...38,499,295 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha involved_in ISO (PMID:24529379) UniProt PMID:24529379 NCBI chr34:12,600,140...12,681,905
Ensembl chr34:12,600,233...12,675,910 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO
IEA		 increased IRS1 binding RGD
Ensembl		 PMID:18922131 GO_REF:0000107 RGD:4108484 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970 		JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:44,826,037...44,838,449
Ensembl chr20:44,826,339...44,836,558 		JBrowse link
G PKLR pyruvate kinase L/R involved_in ISO
IBA		 RGD
GO_Central		 PMID:9395079 GO_REF:0000033 RGD:1625596 NCBI chr 7:42,263,899...42,272,770
Ensembl chr 7:42,263,761...42,272,755 		JBrowse link
G PKM pyruvate kinase M1/2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr30:35,712,853...35,737,643 JBrowse link
G PLA2G1B phospholipase A2 group IB involved_in ISO (PMID:1918029) BHF-UCL PMID:1918029 NCBI chr26:16,248,417...16,257,163
Ensembl chr26:16,248,409...16,257,178 		JBrowse link
G PNPLA3 patatin like phospholipase domain containing 3 ISO RGD PMID:19619606 RGD:14985223 NCBI chr10:21,708,439...21,722,282
Ensembl chr10:21,712,378...21,722,135 		JBrowse link
G POU4F2 POU class 4 homeobox 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:45,030,818...45,034,446
Ensembl chr15:45,031,094...45,032,784 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:26629404) UniProt
MGI		 PMID:26629404 GO_REF:0000024 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
G PPAT phosphoribosyl pyrophosphate amidotransferase ISO RGD PMID:2185659 RGD:2316798 NCBI chr13:48,618,460...48,656,164
Ensembl chr13:48,620,714...48,655,780 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:11884620 RGD:729591 NCBI chr11:22,388,327...22,410,052
Ensembl chr11:22,385,257...22,410,052 		JBrowse link
G PRKCD protein kinase C delta ISO RGD PMID:17046201 RGD:1642545 NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191 		JBrowse link
G PRKCI protein kinase C iota involved_in ISO
IBA
IEA		 RGD
GO_Central
Ensembl		 PMID:12975478 GO_REF:0000033 GO_REF:0000107 RGD:2314946 NCBI chr34:34,767,066...34,839,823
Ensembl chr34:34,766,801...34,837,605 		JBrowse link
G PRKCZ protein kinase C zeta involved_in ISO
IBA		 RGD
GO_Central		 PMID:16525020 GO_REF:0000033 RGD:1642671 NCBI chr 5:57,012,020...57,113,346
Ensembl chr 5:57,012,070...57,112,664 		JBrowse link
G PRKDC protein kinase, DNA-activated, catalytic subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:24,904...243,926
Ensembl chr29:35,007...243,895 		JBrowse link
G PTEN phosphatase and tensin homolog ISO RGD PMID:12700235 RGD:12801493 NCBI chr26:37,853,148...37,913,176
Ensembl chr26:37,835,661...37,913,176 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 ISO RGD PMID:18456732 RGD:401976379 NCBI chr24:36,936,469...37,010,929
Ensembl chr24:36,936,298...37,003,720 		JBrowse link
G RAB10 RAB10, member RAS oncogene family involved_in ISS UniProt GO_REF:0000024 NCBI chr17:20,181,363...20,264,927
Ensembl chr17:20,181,363...20,264,927 		JBrowse link
G RAB13 RAB13, member RAS oncogene family involved_in ISS UniProt GO_REF:0000024 NCBI chr 7:43,152,903...43,156,720
Ensembl chr 7:43,153,002...43,156,720 		JBrowse link
G RAB31 RAB31, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:75,678,896...75,807,716
Ensembl chr 7:75,678,908...75,817,426 		JBrowse link
G RAB8A RAB8A, member RAS oncogene family involved_in ISS UniProt GO_REF:0000024 NCBI chr20:46,334,601...46,351,907
Ensembl chr20:46,334,601...46,351,907 		JBrowse link
G RARRES2 retinoic acid receptor responder 2 ISO RGD PMID:23328001 RGD:15036821 NCBI chr16:14,671,345...14,675,000
Ensembl chr16:14,671,130...14,674,926 		JBrowse link
G RASGRF1 Ras protein specific guanine nucleotide releasing factor 1 ISO RGD PMID:19002579 RGD:10003129 NCBI chr 3:57,995,092...58,085,395
Ensembl chr 3:57,995,786...58,085,380 		JBrowse link
G RB1 RB transcriptional corepressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:3,061,621...3,204,625
Ensembl chr22:3,063,239...3,257,726 		JBrowse link
G RHOQ ras homolog family member Q involved_in ISO (PMID:11309621)
(PMID:11821390)		 BHF-UCL PMID:11309621 PMID:11821390 NCBI chr10:48,766,623...48,807,198
Ensembl chr10:48,768,191...48,804,129 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:24349514) Ensembl
GO_Central
MGI		 PMID:24349514 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:34,387,084...34,590,603
Ensembl chr 9:34,387,091...34,425,292 		JBrowse link
G RXRA retinoid X receptor alpha ISO RGD PMID:9555940 RGD:1643120 NCBI chr 9:50,525,195...50,575,720
Ensembl chr 9:50,484,567...50,573,119 		JBrowse link
G SERPINE1 serpin family E member 1 ISO RGD PMID:10590062 RGD:8547811 NCBI chr 6:8,719,547...8,727,160
Ensembl chr 6:8,720,825...8,726,301 		JBrowse link
G SGK1 serum/glucocorticoid regulated kinase 1 acts_upstream_of_or_within ISO PMID:17715136 MGI PMID:17715136 RGD:8553574 NCBI chr 1:27,086,431...27,196,601
Ensembl chr 1:27,087,361...27,196,521 		JBrowse link
G SHC1 SHC adaptor protein 1 ISO RGD PMID:11884620 RGD:729591 NCBI chr 7:42,501,829...42,509,613
Ensembl chr 7:42,500,185...42,508,276 		JBrowse link
G SLC22A12 solute carrier family 22 member 12 ISO RGD PMID:28679589 RGD:13439745 NCBI chr18:52,541,820...52,550,037
Ensembl chr18:52,542,497...52,549,655 		JBrowse link
G SLC25A33 solute carrier family 25 member 33 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:62,790,116...62,825,644
Ensembl chr 5:62,790,157...62,825,388 		JBrowse link
G SLC29A2 solute carrier family 29 member 2 ISO RGD PMID:17537394 RGD:2316934 NCBI chr18:50,946,647...50,955,085
Ensembl chr18:50,946,724...50,954,413 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:18227281) RGD
GO_Central
MGI
Ensembl
InterPro		 PMID:18227281 PMID:20868366 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 RGD:7349316 NCBI chr 5:32,238,095...32,244,022
Ensembl chr 5:32,238,095...32,244,021 		JBrowse link
G SLC39A14 solute carrier family 39 member 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:34,854,371...34,901,030
Ensembl chr25:34,846,653...34,869,695 		JBrowse link
G SLC9A1 solute carrier family 9 member A1 ISO RGD PMID:20868366 RGD:7349316 NCBI chr 2:73,054,742...73,103,364
Ensembl chr 2:73,054,742...73,103,364 		JBrowse link
G SORBS1 sorbin and SH3 domain containing 1 involved_in ISO (PMID:11001060) BHF-UCL PMID:11001060 NCBI chr28:8,834,530...9,063,739
Ensembl chr28:8,837,338...9,063,777 		JBrowse link
G SP1 Sp1 transcription factor involved_in ISO PMID:26908121 ParkinsonsUK-UCL PMID:26908121 RGD:11059577 NCBI chr27:1,802,587...1,861,187
Ensembl chr27:1,805,184...1,847,226 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:19952103 RGD:2325147 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077 		JBrowse link
G SRD5A1 steroid 5 alpha-reductase 1 ISO RGD PMID:20810561 RGD:4891501 NCBI chr34:7,118,814...7,144,828
Ensembl chr34:7,118,814...7,144,828 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 ISO RGD PMID:10207099 PMID:19158095 PMID:24458133 RGD:2308803 RGD:2308847 RGD:401842379 NCBI chr 5:41,663,809...41,686,764
Ensembl chr 5:41,663,773...41,686,776 		JBrowse link
G SRSF5 serine and arginine rich splicing factor 5 ISO RGD PMID:7686911 RGD:729792 NCBI chr 8:43,514,048...43,519,019
Ensembl chr 8:43,514,076...43,518,481 		JBrowse link
G STAR steroidogenic acute regulatory protein ISO RGD PMID:17023532 RGD:1600072 NCBI chr16:27,326,355...27,331,025
Ensembl chr16:27,326,355...27,331,025 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO RGD PMID:15749807 RGD:1600096 NCBI chr37:1,513,438...1,549,837
Ensembl chr37:1,507,219...1,550,178 		JBrowse link
G SYAP1 synapse associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:12,869,824...12,902,677
Ensembl chr  X:12,869,932...12,901,258 		JBrowse link
G TAT tyrosine aminotransferase ISO RGD PMID:2575213 RGD:597621663 NCBI chr 5:77,365,589...77,378,474
Ensembl chr 5:77,366,138...77,378,419 		JBrowse link
G TBC1D4 TBC1 domain family member 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24349514) RGD
MGI
Ensembl		 PMID:21454690 PMID:24349514 GO_REF:0000107 RGD:7247577 NCBI chr22:29,109,079...29,175,357
Ensembl chr22:29,110,201...29,290,154 		JBrowse link
G TRARG1 trafficking regulator of GLUT4 (SLC2A4) 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:26629404)
(PMID:26240143)		 MGI
UniProt		 PMID:26240143 PMID:26629404 NCBI chr 9:44,560,962...44,577,418
Ensembl chr 9:44,563,419...44,576,972 		JBrowse link
G TRIB3 tribbles pseudokinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:20,450,281...20,461,141
Ensembl chr24:20,451,001...20,457,510 		JBrowse link
G TSC2 TSC complex subunit 2 acts_upstream_of_or_within ISO (PMID:18511518) MGI PMID:18511518 NCBI chr 6:38,865,509...38,898,977
Ensembl chr 6:38,865,507...38,898,960 		JBrowse link
G UBE2B ubiquitin conjugating enzyme E2 B ISO RGD PMID:8048511 RGD:1299378 NCBI chr11:22,523,671...22,541,473
Ensembl chr11:22,525,051...22,540,388 		JBrowse link
G UCHL3 ubiquitin C-terminal hydrolase L3 involved_in ISO (PMID:19837878) UniProt PMID:19837878 NCBI chr22:29,348,962...29,397,944
Ensembl chr22:29,348,706...29,407,965 		JBrowse link
G UCP2 uncoupling protein 2 ISO RGD PMID:18079609 RGD:2313533 NCBI chr21:24,304,410...24,311,392
Ensembl chr21:24,304,457...24,311,128 		JBrowse link
G USF1 upstream transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:21,412,943...21,419,072
Ensembl chr38:21,413,050...21,418,569 		JBrowse link
G VAMP2 vesicle associated membrane protein 2 acts_upstream_of_or_within ISO (PMID:18227281) MGI PMID:18227281 NCBI chr 5:32,975,372...32,977,967 JBrowse link
G VLDLR very low density lipoprotein receptor ISO RGD PMID:15878964 RGD:1625575 NCBI chr 1:91,242,010...91,277,030
Ensembl chr 1:91,241,509...91,272,495 		JBrowse link
G WDTC1 WD and tetratricopeptide repeats 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17767906) Ensembl
MGI		 PMID:17767906 GO_REF:0000107 NCBI chr 2:72,949,526...73,012,429
Ensembl chr 2:72,950,982...73,012,434 		JBrowse link
G XBP1 X-box binding protein 1 involved_in ISO (PMID:20348926) UniProt PMID:20348926 NCBI chr26:22,162,675...22,168,149
Ensembl chr26:22,163,222...22,168,105 		JBrowse link
G YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma ISO RGD PMID:21454690 RGD:7247577 NCBI chr 6:7,504,834...7,548,097
Ensembl chr 6:7,507,608...7,532,409 		JBrowse link
G ZFP36L1 ZFP36 ring finger protein like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:42,663,287...42,668,665
Ensembl chr 8:42,664,223...42,668,514 		JBrowse link
glucose import in response to insulin stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SGCB sarcoglycan beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19494113) Ensembl
MGI		 PMID:19494113 GO_REF:0000107 NCBI chr13:44,969,483...44,987,274
Ensembl chr13:44,972,473...44,987,184 		JBrowse link
G SLC27A1 solute carrier family 27 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:45,309,094...45,341,101
Ensembl chr20:45,310,088...45,340,230 		JBrowse link
G SLC27A4 solute carrier family 27 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:55,164,106...55,177,567
Ensembl chr 9:55,164,817...55,177,511 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:26629404) UniProt
MGI
Ensembl		 PMID:26629404 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:32,238,095...32,244,022
Ensembl chr 5:32,238,095...32,244,021 		JBrowse link
G TRARG1 trafficking regulator of GLUT4 (SLC2A4) 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:26629404)
(PMID:26240143)		 MGI
UniProt		 PMID:26240143 PMID:26629404 NCBI chr 9:44,560,962...44,577,418
Ensembl chr 9:44,563,419...44,576,972 		JBrowse link
G ZDHHC7 zinc finger DHHC-type palmitoyltransferase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:67,554,310...67,580,042
Ensembl chr 5:67,566,563...67,578,556 		JBrowse link
insulin receptor recycling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTSD cathepsin D involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:46,010,440...46,019,457
Ensembl chr18:46,010,440...46,019,457 		JBrowse link
G IDE insulin degrading enzyme involved_in ISO (PMID:27703010) MGI PMID:27703010 NCBI chr28:6,844,480...6,967,713
Ensembl chr28:6,844,055...6,967,713 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:36,936,469...37,010,929
Ensembl chr24:36,936,298...37,003,720 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719 		JBrowse link
G SORL1 sortilin related receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:12,493,750...12,650,530
Ensembl chr 5:12,431,377...12,650,784 		JBrowse link
insulin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193 		JBrowse link
G AKT2 AKT serine/threonine kinase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21148297) Ensembl
MGI		 PMID:21148297 GO_REF:0000107 NCBI chr 1:113,359,038...113,407,119
Ensembl chr 1:113,359,575...113,407,131 		JBrowse link
G ALK ALK receptor tyrosine kinase involved_in IEA GOC GO_REF:0000108 NCBI chr17:23,010,308...23,688,841
Ensembl chr17:23,010,308...23,688,841 		JBrowse link
G ANKRD26 ankyrin repeat domain containing 26 acts_upstream_of ISO (PMID:21842266) MGI PMID:21842266 NCBI chr 2:6,230,466...6,402,360 JBrowse link
G APC APC regulator of WNT signaling pathway involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:252,052...380,506
Ensembl chr 3:253,081...322,993 		JBrowse link
G APPL1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr20:33,123,577...33,166,831
Ensembl chr20:33,130,723...33,166,792 		JBrowse link
G BCAR1 BCAR1 scaffold protein, Cas family member involved_in ISO PMID:9627109 UniProt PMID:9627109 RGD:8553632 NCBI chr 5:75,463,906...75,499,557
Ensembl chr 5:75,463,926...75,512,476 		JBrowse link
G BCAR3 BCAR3 adaptor protein, NSP family member involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:55,276,300...55,525,246
Ensembl chr 6:55,347,955...55,525,246 		JBrowse link
G C2CD5 C2 calcium dependent domain containing 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:24,697,036...24,798,138
Ensembl chr27:24,697,016...24,797,543 		JBrowse link
G CAV2 caveolin 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr14:55,437,622...55,445,481
Ensembl chr14:55,437,622...55,445,469 		JBrowse link
G COL6A1 collagen type VI alpha 1 chain involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19114551) Ensembl
MGI		 PMID:19114551 GO_REF:0000107 NCBI chr31:39,301,718...39,319,895
Ensembl chr31:39,301,748...39,448,062 		JBrowse link
G CSRP3 cysteine and glycine rich protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29634311) Ensembl
MGI		 PMID:29634311 GO_REF:0000107 NCBI chr21:41,300,277...41,318,788
Ensembl chr21:41,300,425...41,318,738 		JBrowse link
G DNAI1 dynein axonemal intermediate chain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:51,080,080...51,205,381
Ensembl chr11:51,106,370...51,237,467 		JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 acts_upstream_of_or_within ISO (PMID:7629182) MGI PMID:7629182 NCBI chr16:27,389,850...27,410,154
Ensembl chr16:27,390,181...27,410,110 		JBrowse link
G EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8939971) Ensembl
MGI		 PMID:8939971 GO_REF:0000107 NCBI chr 4:21,339,037...21,364,224
Ensembl chr 4:21,339,045...21,358,072 		JBrowse link
G EPHA2 EPH receptor A2 involved_in IEA GOC GO_REF:0000108 NCBI chr 2:81,534,130...81,561,722
Ensembl chr 2:81,534,125...81,561,725 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 involved_in IEA GOC GO_REF:0000108 NCBI chr 9:22,760,373...22,785,367
Ensembl chr 9:22,759,256...22,785,294 		JBrowse link
G FER FER tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:2,863,804...3,295,999
Ensembl chr 3:2,867,726...3,295,999 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 involved_in IEA GOC GO_REF:0000108 NCBI chr28:31,303,882...31,411,015
Ensembl chr28:31,303,894...31,411,621 		JBrowse link
G FLT3 fms related receptor tyrosine kinase 3 involved_in IEA GOC GO_REF:0000108 NCBI chr25:11,551,372...11,670,891
Ensembl chr25:11,581,206...11,692,284 		JBrowse link
G FOXC2 forkhead box C2 involved_in ISO (PMID:16456100) UniProt PMID:16456100 NCBI chr 5:66,234,336...66,296,007
Ensembl chr 5:66,294,176...66,295,693 		JBrowse link
G FOXC2 forkhead box C2 involved_in IEA Ensembl GO_REF:0000107
G FOXO1 forkhead box O1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:29867121)
(PMID:12488434)		 MGI
GO_Central		 PMID:12488434 PMID:29867121 GO_REF:0000033 NCBI chr25:603,433...706,961
Ensembl chr25:603,543...702,825 		JBrowse link
G FOXO4 forkhead box O4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:55,469,738...55,477,699
Ensembl chr  X:55,469,382...55,477,699 		JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:22,495,001...22,556,264
Ensembl chr35:22,495,073...22,554,105 		JBrowse link
G GPR21 G protein-coupled receptor 21 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:22653059) Ensembl
MGI		 PMID:22653059 GO_REF:0000107 NCBI chr 9:59,760,384...59,764,309 JBrowse link
G GRB10 growth factor receptor bound protein 10 involved_in IBA GO_Central GO_REF:0000033 NCBI chr18:1,890,689...2,014,836
Ensembl chr18:1,890,792...2,014,839 		JBrowse link
G GRB14 growth factor receptor bound protein 14 involved_in ISO
IBA		 RGD
GO_Central		 PMID:9748281 GO_REF:0000033 RGD:61620 NCBI chr36:9,711,885...9,843,266
Ensembl chr36:9,712,142...9,721,769 		JBrowse link
G GRB2 growth factor receptor bound protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:5,108,128...5,182,091
Ensembl chr 9:5,117,164...5,180,296 		JBrowse link
G GRB7 growth factor receptor bound protein 7 NOT|involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:22,743,370...22,751,936
Ensembl chr 9:22,743,402...22,750,896 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:112,129,116...112,138,714
Ensembl chr 1:112,103,825...112,138,559 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta involved_in IBA GO_Central GO_REF:0000033 NCBI chr33:23,458,369...23,659,878
Ensembl chr33:23,463,767...23,659,666 		JBrowse link
G HMGA1 high mobility group AT-hook 1 acts_upstream_of_or_within ISO (PMID:22355763)
(PMID:15924147)
(PMID:29867121)		 MGI PMID:15924147 PMID:22355763 PMID:29867121 NCBI chr12:3,528,818...3,538,533
Ensembl chr12:3,533,102...3,538,533 		JBrowse link
G HRAS HRas proto-oncogene, GTPase involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:25,642,844...25,644,717
Ensembl chr18:25,642,844...25,644,717 		JBrowse link
G IGF1 insulin like growth factor 1 involved_in ISO (PMID:22635104) ARUK-UCL PMID:22635104 NCBI chr15:41,203,320...41,275,964
Ensembl chr15:41,202,518...41,275,794 		JBrowse link
G IGF1R insulin like growth factor 1 receptor involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:41,795,337...42,096,255
Ensembl chr 3:41,794,623...42,090,387 		JBrowse link
G IGF2 insulin like growth factor 2 involved_in ISO (PMID:20032056) BHF-UCL PMID:20032056 NCBI chr18:46,294,036...46,311,982
Ensembl chr18:46,294,019...46,311,982 		JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 ISO RGD PMID:11784721 RGD:729306 NCBI chr16:1,037,169...1,040,996
Ensembl chr16:1,037,162...1,167,094 		JBrowse link
G INS insulin acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12805218) MGI
Ensembl		 PMID:12805218 GO_REF:0000107 NCBI chr18:46,324,047...46,324,933
Ensembl chr18:46,324,041...46,325,122 		JBrowse link
G INSR insulin receptor involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:12488434) RGD
GO_Central
MGI
Ensembl		 PMID:12488434 PMID:12850498 PMID:12891559 PMID:15520221 PMID:26300412 More... GO_REF:0000033 GO_REF:0000107 RGD:11529553 RGD:1299201 RGD:14700925 RGD:1580595 RGD:2306052 NCBI chr20:52,017,261...52,136,061
Ensembl chr20:52,021,887...52,136,046 		JBrowse link
G INSRR insulin receptor related receptor involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:41,161,036...41,176,739
Ensembl chr 7:41,161,333...41,175,940 		JBrowse link
G IRS1 insulin receptor substrate 1 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:15249583)
(PMID:9813005)		 InterPro
GO_Central
MGI
Ensembl		 PMID:9813005 PMID:15249583 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr25:39,624,554...39,687,991 JBrowse link
G IRS1 insulin receptor substrate 1 involved_in IEA InterPro GO_REF:0000002 Ensembl chr25:39,684,250...39,687,971 JBrowse link
G IRS2 insulin receptor substrate 2 involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:9813005)
(PMID:12488434)		 RGD
GO_Central
MGI
Ensembl
InterPro		 PMID:9813005 PMID:12488434 PMID:12891559 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 RGD:1299201 NCBI chr22:58,197,016...58,229,026
Ensembl chr22:58,223,387...58,227,535 		JBrowse link
G IRS4 insulin receptor substrate 4 involved_in IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr  X:82,275,642...82,292,398
Ensembl chr  X:82,276,187...82,292,375 		JBrowse link
G KDR kinase insert domain receptor involved_in IEA GOC GO_REF:0000108 NCBI chr13:47,442,861...47,484,574
Ensembl chr13:47,442,764...47,485,042 		JBrowse link
G KIT KIT proto-oncogene, receptor tyrosine kinase involved_in IEA GOC GO_REF:0000108 NCBI chr13:47,108,442...47,190,935
Ensembl chr13:47,108,504...47,190,029 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:22,261,753...22,296,704
Ensembl chr27:22,257,941...22,293,369 		JBrowse link
G LOC100856339 phosphatidylinositol 3-kinase regulatory subunit gamma involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:7542745) Ensembl
GO_Central
MGI		 PMID:7542745 GO_REF:0000033 GO_REF:0000107 NCBI chr15:14,222,059...14,357,200
Ensembl chr15:14,235,824...14,353,832 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in ISO (PMID:20889126) MGI PMID:20889126 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425 		JBrowse link
G MET MET proto-oncogene, receptor tyrosine kinase involved_in IEA GOC GO_REF:0000108 NCBI chr14:55,599,047...55,711,626
Ensembl chr14:55,598,337...55,724,027 		JBrowse link
G MTCL2 microtubule crosslinking factor 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr24:25,525,564...25,602,158
Ensembl chr24:25,531,865...25,600,727 		JBrowse link
G NAMPT nicotinamide phosphoribosyltransferase NOT|involved_in ISO (PMID:17983582) BHF-UCL PMID:17983582 NCBI chr18:14,110,045...14,211,268
Ensembl chr18:13,993,022...14,208,657 		JBrowse link
G NCOA5 nuclear receptor coactivator 5 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:24332041) Ensembl
MGI		 PMID:24332041 GO_REF:0000107 NCBI chr24:33,323,645...33,352,836
Ensembl chr24:33,322,650...33,352,809 		JBrowse link
G NDEL1 nudE neurodevelopment protein 1 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:33,187,614...33,244,483
Ensembl chr 5:33,204,452...33,266,052 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 ISO RGD PMID:11781314 RGD:625467 NCBI chr18:42,333,173...42,346,152
Ensembl chr18:42,333,202...42,341,236 		JBrowse link
G PDGFRA platelet derived growth factor receptor alpha involved_in IEA GOC GO_REF:0000108 NCBI chr13:46,729,722...46,775,828
Ensembl chr13:46,730,703...46,773,278 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta involved_in IEA GOC GO_REF:0000108 NCBI chr 4:58,925,922...58,963,639
Ensembl chr 4:58,926,351...58,962,283 		JBrowse link
G PDK2 pyruvate dehydrogenase kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:26,099,457...26,116,094
Ensembl chr 9:26,100,343...26,115,423 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr14:20,825,861...20,839,290
Ensembl chr14:20,827,831...20,839,256 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,426,464...38,506,520
Ensembl chr 6:38,431,600...38,499,295 		JBrowse link
G PHIP pleckstrin homology domain interacting protein acts_upstream_of_or_within ISO (PMID:11018022) MGI PMID:11018022 NCBI chr12:39,899,738...40,015,795
Ensembl chr12:39,904,603...40,032,194 		JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha involved_in ISO (PMID:20197055) MGI PMID:20197055 NCBI chr34:12,600,140...12,681,905
Ensembl chr34:12,600,233...12,675,910 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO
IBA
IEA		 RGD
GO_Central
Ensembl		 PMID:15161606 GO_REF:0000033 GO_REF:0000107 RGD:1625251 NCBI chr 2:53,447,802...53,527,563
Ensembl chr 2:53,448,286...53,524,970 		JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr20:44,826,037...44,838,449
Ensembl chr20:44,826,339...44,836,558 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15632081) Ensembl
MGI		 PMID:15632081 GO_REF:0000107 NCBI chr24:36,936,469...37,010,929
Ensembl chr24:36,936,298...37,003,720 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15632081) Ensembl
MGI		 PMID:15632081 GO_REF:0000107 NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719 		JBrowse link
G PTPRA protein tyrosine phosphatase receptor type A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14733908) Ensembl
MGI		 PMID:14733908 GO_REF:0000107 NCBI chr24:18,224,355...18,395,650
Ensembl chr24:18,224,801...18,296,350 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:5,892,839...5,972,672
Ensembl chr20:5,892,834...5,972,090 		JBrowse link
G RARRES2 retinoic acid receptor responder 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:14,671,345...14,675,000
Ensembl chr16:14,671,130...14,674,926 		JBrowse link
G RHOQ ras homolog family member Q involved_in ISO (PMID:11309621) BHF-UCL PMID:11309621 NCBI chr10:48,766,623...48,807,198
Ensembl chr10:48,768,191...48,804,129 		JBrowse link
G SH2B2 SH2B adaptor protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10196204) Ensembl
MGI		 PMID:10196204 GO_REF:0000107 NCBI chr 6:7,795,756...7,820,010
Ensembl chr 6:7,795,373...7,819,843 		JBrowse link
G SHC1 SHC adaptor protein 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:42,501,829...42,509,613
Ensembl chr 7:42,500,185...42,508,276 		JBrowse link
G SIK2 salt inducible kinase 2 acts_upstream_of_or_within ISO (PMID:12624099) MGI PMID:12624099 NCBI chr 5:21,354,127...21,479,891
Ensembl chr 5:21,358,902...21,479,841 		JBrowse link
G SLC2A8 solute carrier family 2 member 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10860996) Ensembl
MGI		 PMID:10860996 GO_REF:0000107 NCBI chr 9:55,921,635...55,928,753
Ensembl chr 9:55,921,635...55,928,753 		JBrowse link
G SLC39A14 solute carrier family 39 member 14 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:27703010) Ensembl
UniProt		 PMID:27703010 GO_REF:0000107 NCBI chr25:34,854,371...34,901,030
Ensembl chr25:34,846,653...34,869,695 		JBrowse link
G SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17074803) Ensembl
MGI		 PMID:17074803 GO_REF:0000107 NCBI chr20:41,165,593...41,337,237
Ensembl chr20:41,165,522...41,335,917 		JBrowse link
G SOCS7 suppressor of cytokine signaling 7 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:16127460) MGI
GO_Central		 PMID:16127460 GO_REF:0000033 NCBI chr 9:23,775,349...23,809,325
Ensembl chr 9:23,776,827...23,803,994 		JBrowse link
G SORBS1 sorbin and SH3 domain containing 1 involved_in ISO (PMID:9447983) UniProt PMID:9447983 NCBI chr28:8,834,530...9,063,739
Ensembl chr28:8,837,338...9,063,777 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:31,007,940...31,181,569
Ensembl chr17:31,009,257...31,142,063 		JBrowse link
G SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:26,636,849...26,698,837
Ensembl chr 8:26,637,895...26,717,781 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17074803) Ensembl
MGI		 PMID:17074803 GO_REF:0000107 NCBI chr 5:41,663,809...41,686,764
Ensembl chr 5:41,663,773...41,686,776 		JBrowse link
G STXBP4 syntaxin binding protein 4 involved_in
acts_upstream_of_or_within		 IEA
IBA
ISO		 (PMID:10394363) Ensembl
GO_Central
MGI		 PMID:10394363 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:30,079,797...30,293,750
Ensembl chr 9:30,092,289...30,236,135 		JBrowse link
G TMEM87A transmembrane protein 87A acts_upstream_of_or_within ISO (PMID:9507006) MGI PMID:9507006 NCBI chr30:9,215,585...9,253,712
Ensembl chr30:9,216,702...9,253,700 		JBrowse link
G ZNF106 zinc finger protein 106 involved_in IBA GO_Central GO_REF:0000033 NCBI chr30:9,389,184...9,452,891
Ensembl chr30:9,392,761...9,452,850 		JBrowse link
negative regulation of cellular response to insulin stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:33,192,261...33,243,034
Ensembl chr10:33,191,602...33,242,669 		JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:23913704 RGD:13792716 NCBI chr18:50,148,566...50,167,422
Ensembl chr18:50,148,598...50,167,428 		JBrowse link
G LPL lipoprotein lipase ISO RGD PMID:25931001 RGD:13794384 NCBI chr25:37,078,306...37,102,729
Ensembl chr25:37,079,756...37,102,700 		JBrowse link
G MIR15B microRNA mir-15b involved_in ISO (PMID:26179126) ARUK-UCL PMID:26179126 NCBI chr34:26,460,663...26,460,722
Ensembl chr34:26,460,645...26,460,741 		JBrowse link
G MIR195 microRNA mir-195 involved_in ISO (PMID:25240198) ARUK-UCL PMID:25240198 NCBI chr 5:32,045,450...32,045,510
Ensembl chr 5:32,045,450...32,045,510 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma involved_in ISO (PMID:11387233) BHF-UCL PMID:11387233 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
G SCO1 synthesis of cytochrome C oxidase 1 acts_upstream_of_or_within ISO (PMID:28973536) MGI PMID:28973536 NCBI chr 5:34,957,358...34,971,684
Ensembl chr 5:34,957,785...34,971,661 		JBrowse link
negative regulation of insulin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHSG alpha 2-HS glycoprotein ISO RGD PMID:2766355 RGD:632173 NCBI chr34:19,221,034...19,228,866
Ensembl chr34:19,221,107...19,228,716 		JBrowse link
G ANKRD26 ankyrin repeat domain containing 26 acts_upstream_of_or_within ISO (PMID:21842266) MGI PMID:21842266 NCBI chr 2:6,230,466...6,402,360 JBrowse link
G BLVRB biliverdin reductase B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:113,244,484...113,258,170
Ensembl chr 1:113,244,503...113,258,073 		JBrowse link
G CUL7 cullin 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:11,559,637...11,574,320
Ensembl chr12:11,559,667...11,575,023 		JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 involved_in ISO (PMID:17849011), (PMID:7830796) BHF-UCL PMID:7830796 PMID:17849011 NCBI chr 1:251,985...322,081
Ensembl chr 1:252,103...322,718 		JBrowse link
G FBXW8 F-box and WD repeat domain containing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:13,520,605...13,640,975
Ensembl chr26:13,412,189...13,638,258 		JBrowse link
G GPR21 G protein-coupled receptor 21 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22653059) Ensembl
MGI		 PMID:22653059 GO_REF:0000107 NCBI chr 9:59,760,384...59,764,309 JBrowse link
G GRB10 growth factor receptor bound protein 10 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr18:1,890,689...2,014,836
Ensembl chr18:1,890,792...2,014,839 		JBrowse link
G GRB14 growth factor receptor bound protein 14 involved_in ISO
IBA
IEA		 RGD
GO_Central
Ensembl		 PMID:9748281 PMID:18657188 GO_REF:0000033 GO_REF:0000107 RGD:2307023 RGD:61620 NCBI chr36:9,711,885...9,843,266
Ensembl chr36:9,712,142...9,721,769 		JBrowse link
G GRB7 growth factor receptor bound protein 7 NOT|involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:22,743,370...22,751,936
Ensembl chr 9:22,743,402...22,750,896 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:112,129,116...112,138,714
Ensembl chr 1:112,103,825...112,138,559 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta involved_in ISO PMID:8524413 BHF-UCL PMID:8524413 RGD:8554844 NCBI chr33:23,458,369...23,659,878
Ensembl chr33:23,463,767...23,659,666 		JBrowse link
G IL1B interleukin 1 beta involved_in ISO (PMID:16865359) BHF-UCL PMID:16865359 NCBI chr17:37,019,329...37,033,388
Ensembl chr17:37,019,329...37,024,458 		JBrowse link
G INPP5K inositol polyphosphate-5-phosphatase K involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:45,660,445...45,680,407
Ensembl chr 9:45,660,446...45,680,363 		JBrowse link
G INPPL1 inositol polyphosphate phosphatase like 1 ISO RGD PMID:11692174 RGD:2312443 NCBI chr21:25,900,308...25,914,527
Ensembl chr21:25,900,900...25,915,577 		JBrowse link
G IRS1 insulin receptor substrate 1 involved_in ISO PMID:15069075 BHF-UCL PMID:15069075 RGD:8554248 NCBI chr25:39,624,554...39,687,991 JBrowse link
G KANK1 KN motif and ankyrin repeat domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:89,446,340...89,618,716
Ensembl chr 1:89,480,399...89,618,143 		JBrowse link
G LEP leptin involved_in ISO (PMID:14677856) CACAO PMID:14677856 NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395 		JBrowse link
G LONP1 lon peptidase 1, mitochondrial acts_upstream_of_or_within ISO (PMID:9813005) MGI PMID:9813005 NCBI chr20:54,312,678...54,334,142
Ensembl chr20:54,312,678...54,334,141 		JBrowse link
G MIR143 microRNA mir-143 acts_upstream_of_or_within ISO (PMID:21441927) MGI PMID:21441927 NCBI chr 4:59,534,535...59,534,589
Ensembl chr 4:59,534,535...59,534,594 		JBrowse link
G MIR15B microRNA mir-15b involved_in ISO (PMID:26179126) ARUK-UCL PMID:26179126 NCBI chr34:26,460,663...26,460,722
Ensembl chr34:26,460,645...26,460,741 		JBrowse link
G MIR195 microRNA mir-195 involved_in ISO (PMID:25240198) ARUK-UCL PMID:25240198 NCBI chr 5:32,045,450...32,045,510
Ensembl chr 5:32,045,450...32,045,510 		JBrowse link
G MSTN myostatin involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:729,172...734,255
Ensembl chr37:729,172...734,362 		JBrowse link
G NCK1 NCK adaptor protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:33,297,660...33,374,025
Ensembl chr23:33,297,756...33,372,534 		JBrowse link
G NCL nucleolin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9813005) Ensembl
MGI		 PMID:9813005 GO_REF:0000107 NCBI chr25:43,330,524...43,384,909
Ensembl chr25:43,330,799...43,384,258 		JBrowse link
G NCOA5 nuclear receptor coactivator 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24332041) Ensembl
MGI		 PMID:24332041 GO_REF:0000107 NCBI chr24:33,323,645...33,352,836
Ensembl chr24:33,322,650...33,352,809 		JBrowse link
G NUCB2 nucleobindin 2 ISO RGD PMID:22486620 RGD:9831186 NCBI chr21:39,868,756...39,918,724
Ensembl chr21:39,874,781...39,918,689 		JBrowse link
G PID1 phosphotyrosine interaction domain containing 1 involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr25:41,424,307...41,649,736
Ensembl chr25:41,425,811...41,652,672 		JBrowse link
G PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:10,464,019...10,642,365
Ensembl chr 2:10,463,010...10,640,327 		JBrowse link
G PIP4K2B phosphatidylinositol-5-phosphate 4-kinase type 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:23,445,350...23,473,195
Ensembl chr 9:23,445,482...23,470,184 		JBrowse link
G PIP4K2C phosphatidylinositol-5-phosphate 4-kinase type 2 gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:1,670,076...1,680,975
Ensembl chr10:1,672,380...1,680,840 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 ISO RGD PMID:20501641 RGD:6484547 NCBI chr 4:68,579,061...68,614,548
Ensembl chr 4:68,579,037...68,611,841 		JBrowse link
G PRKCA protein kinase C alpha acts_upstream_of_or_within ISO (PMID:11923480) MGI PMID:11923480 NCBI chr 9:13,638,106...13,879,571
Ensembl chr 9:13,644,010...13,967,630 		JBrowse link
G PRKCB protein kinase C beta involved_in ISO PMID:11714718 UniProt PMID:11714718 RGD:8553365 NCBI chr 6:21,742,970...22,064,360
Ensembl chr 6:21,742,973...22,065,185 		JBrowse link
G PRKCD protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:36,723,491...36,751,982
Ensembl chr20:36,723,809...36,752,191 		JBrowse link
G PRKCQ protein kinase C theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:29,319,123...29,505,338
Ensembl chr 2:29,318,870...29,505,337 		JBrowse link
G PRKCZ protein kinase C zeta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:57,012,020...57,113,346
Ensembl chr 5:57,012,070...57,112,664 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:78,160,564...78,252,382
Ensembl chr 7:78,160,589...78,252,719 		JBrowse link
G PTPRE protein tyrosine phosphatase receptor type E involved_in ISO PMID:15738637
(PMID:18006633)		 UniProt PMID:15738637 PMID:18006633 RGD:8553759 NCBI chr28:36,761,314...36,904,902
Ensembl chr28:36,746,822...36,902,325 		JBrowse link
G PTPRF protein tyrosine phosphatase receptor type F ISO RGD PMID:8557682 RGD:1642757 NCBI chr15:16,590,908...16,666,673
Ensembl chr15:16,591,308...16,666,673 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:41,586,262...41,635,386
Ensembl chr18:41,586,112...41,635,308 		JBrowse link
G RBX1 ring-box 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:24,265,733...24,280,253
Ensembl chr10:24,266,408...24,280,235 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO RGD PMID:18073321 RGD:2298860 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15249583) Ensembl
MGI		 PMID:15249583 GO_REF:0000107 NCBI chr 9:34,387,084...34,590,603
Ensembl chr 9:34,387,091...34,425,292 		JBrowse link
G RPS6KB2 ribosomal protein S6 kinase B2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15249583) Ensembl
MGI		 PMID:15249583 GO_REF:0000107 NCBI chr18:50,034,318...50,039,892
Ensembl chr18:50,034,364...50,040,250 		JBrowse link
G SLC27A4 solute carrier family 27 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:55,164,106...55,177,567
Ensembl chr 9:55,164,817...55,177,511 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 acts_upstream_of_or_within ISO (PMID:15169905) MGI PMID:15169905 NCBI chr 6:31,511,003...31,511,995
Ensembl chr 6:31,509,268...31,511,557 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15169905) Ensembl
MGI		 PMID:15169905 GO_REF:0000107 NCBI chr 9:2,859,267...2,859,944 JBrowse link
G TNS2 tensin 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr27:2,096,287...2,112,626
Ensembl chr27:2,096,616...2,113,619 		JBrowse link
G TRIM72 tripartite motif containing 72 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23965929) Ensembl
MGI		 PMID:23965929 GO_REF:0000107 NCBI chr 6:17,031,175...17,053,399
Ensembl chr 6:17,031,913...17,039,556 		JBrowse link
G TSC2 TSC complex subunit 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:38,865,509...38,898,977
Ensembl chr 6:38,865,507...38,898,960 		JBrowse link
G ZNF592 zinc finger protein 592 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9813005) Ensembl
MGI		 PMID:9813005 GO_REF:0000107 NCBI chr 3:53,980,438...54,056,011
Ensembl chr 3:53,990,434...54,114,486 		JBrowse link
positive regulation of cellular response to insulin stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ECHDC3 enoyl-CoA hydratase domain containing 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:24,600,563...24,619,948
Ensembl chr 2:24,599,709...24,619,958 		JBrowse link
G ESRRA estrogen related receptor alpha ISO RGD PMID:20215575 RGD:10401858 NCBI chr18:52,755,547...52,762,938
Ensembl chr18:52,756,344...52,763,355 		JBrowse link
G LOC609026 C1q and TNF related 9 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23842676) Ensembl
MGI		 PMID:23842676 GO_REF:0000107 NCBI chr25:14,735,370...14,748,054 JBrowse link
G MYO1C myosin IC involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:12490950) RGD
Ensembl
MGI		 PMID:12490950 PMID:22918957 GO_REF:0000107 RGD:11073622 NCBI chr 9:45,635,295...45,658,226
Ensembl chr 9:45,636,208...45,658,035 		JBrowse link
G MYO5A myosin VA ISO RGD PMID:24478457 RGD:11532776 NCBI chr30:17,990,521...18,122,160
Ensembl chr30:17,888,419...18,213,061 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase ISO RGD PMID:24085037 RGD:13208948 NCBI chr23:52,068,123...52,154,410
Ensembl chr23:52,068,118...52,151,593 		JBrowse link
positive regulation of insulin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOR1 adiponectin receptor 1 ISO RGD PMID:18394428 RGD:2317907 NCBI chr 7:240,035...254,287
Ensembl chr 7:240,065...282,845 		JBrowse link
G AGT angiotensinogen ISO RGD PMID:24184594 RGD:11039409 NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880 		JBrowse link
G C1QTNF12 C1q and TNF related 12 acts_upstream_of_or_within ISO (PMID:22275362) MGI PMID:22275362 NCBI chr 5:56,433,555...56,438,419
Ensembl chr 5:56,433,552...56,438,339 		JBrowse link
G ERFE erythroferrone involved_in IBA GO_Central GO_REF:0000033 NCBI chr25:48,656,576...48,665,620 JBrowse link
G GKAP1 G kinase anchoring protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:75,662,369...75,732,663
Ensembl chr 1:75,674,901...75,732,661 		JBrowse link
G IGF2 insulin like growth factor 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr18:46,294,036...46,311,982
Ensembl chr18:46,294,019...46,311,982 		JBrowse link
G INS insulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:46,324,047...46,324,933
Ensembl chr18:46,324,041...46,325,122 		JBrowse link
G IRS1 insulin receptor substrate 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:39,624,554...39,687,991 JBrowse link
G LEP leptin ISO RGD PMID:20977462 RGD:5128575 NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395 		JBrowse link
G MARCKS myristoylated alanine rich protein kinase C substrate ISO RGD PMID:19252893 RGD:9685323 NCBI chr12:69,980,003...69,987,150
Ensembl chr12:69,980,433...69,984,848 		JBrowse link
G MFN2 mitofusin 2 ISO RGD PMID:25034891 RGD:13204821 NCBI chr 2:84,284,719...84,310,715
Ensembl chr 2:84,284,719...84,308,225 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:39,497,313...39,608,120
Ensembl chr15:39,536,290...39,608,116 		JBrowse link
G NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24931609) Ensembl
MGI		 PMID:24931609 GO_REF:0000107 NCBI chr38:2,157,109...2,188,543
Ensembl chr38:2,160,233...2,170,560 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase ISO RGD PMID:24085037 RGD:13208948 NCBI chr23:52,068,123...52,154,410
Ensembl chr23:52,068,118...52,151,593 		JBrowse link
G OSBPL8 oxysterol binding protein like 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21441927) Ensembl
MGI		 PMID:21441927 GO_REF:0000107 NCBI chr15:19,339,385...19,441,583
Ensembl chr15:19,142,987...19,637,708 		JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 ISO RGD PMID:25199455 RGD:11533947 NCBI chr21:21,341,530...21,409,535
Ensembl chr21:21,265,484...21,408,416 		JBrowse link
G PRKCZ protein kinase C zeta involved_in ISO PMID:9374484 UniProt PMID:9374484 RGD:8553908 NCBI chr 5:57,012,020...57,113,346
Ensembl chr 5:57,012,070...57,112,664 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481 		JBrowse link
G SERPINA12 serpin family A member 12 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22837305) Ensembl
MGI		 PMID:22837305 GO_REF:0000107 NCBI chr 8:63,497,542...63,511,701
Ensembl chr 8:63,497,849...63,512,171 		JBrowse link
G SIRT1 sirtuin 1 involved_in ISO (PMID:21241768) UniProt PMID:21241768 NCBI chr 4:19,188,616...19,220,031
Ensembl chr 4:19,188,675...19,218,279 		JBrowse link
G SNX5 sorting nexin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:5,085,140...5,110,942
Ensembl chr24:5,084,986...5,110,283 		JBrowse link
G SORBS1 sorbin and SH3 domain containing 1 involved_in ISO (PMID:11001060) UniProt PMID:11001060 NCBI chr28:8,834,530...9,063,739
Ensembl chr28:8,837,338...9,063,777 		JBrowse link
G SORL1 sortilin related receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:12,493,750...12,650,530
Ensembl chr 5:12,431,377...12,650,784 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:14985360 RGD:1581139 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077 		JBrowse link
G TSC2 TSC complex subunit 2 acts_upstream_of_or_within ISO (PMID:15249583) MGI PMID:15249583 NCBI chr 6:38,865,509...38,898,977
Ensembl chr 6:38,865,507...38,898,960 		JBrowse link
G ZBTB7B zinc finger and BTB domain containing 7B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:42,468,376...42,482,219
Ensembl chr 7:42,468,247...42,483,436 		JBrowse link
regulation of cellular response to insulin stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:30,547,009...30,674,094
Ensembl chr15:30,547,015...30,616,429 		JBrowse link
G BGLAP bone gamma-carboxyglutamate protein involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:41,630,092...41,630,976
Ensembl chr 7:41,630,098...41,665,791 		JBrowse link
G CUL3 cullin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:37,730,903...37,819,851
Ensembl chr25:37,733,229...37,800,886 		JBrowse link
G GLA galactosidase alpha involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:75,311,536...75,320,391
Ensembl chr  X:75,311,536...75,320,249 		JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:22,495,001...22,556,264
Ensembl chr35:22,495,073...22,554,105 		JBrowse link
G KBTBD2 kelch repeat and BTB domain containing 2 involved_in ISO (PMID:27708159) UniProt PMID:27708159 NCBI chr14:44,941,116...45,001,887
Ensembl chr14:44,941,448...44,994,047 		JBrowse link
G USO1 USO1 vesicle transport factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15800058) Ensembl
MGI		 PMID:15800058 GO_REF:0000107 NCBI chr32:305,895...395,113
Ensembl chr32:305,935...394,896 		JBrowse link
regulation of insulin receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FFAR3 free fatty acid receptor 3 involved_in ISO (PMID:24748202) UniProt PMID:24748202 NCBI chr 1:117,251,604...117,257,048 JBrowse link
G FFAR3 involved_in IEA Ensembl GO_REF:0000107
G FUT7 fucosyltransferase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:48,604,879...48,609,292
Ensembl chr 9:48,606,435...48,609,303 		JBrowse link
G MIR494 microRNA mir-494 acts_upstream_of_or_within ISO (PMID:24349514) MGI PMID:24349514 NCBI chr 8:69,261,385...69,261,465
Ensembl chr 8:69,261,385...69,261,465 		JBrowse link
G MZB1 marginal zone B and B1 cell specific protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:34,710,487...34,712,660
Ensembl chr 2:34,706,007...34,712,626 		JBrowse link
G NUCKS1 nuclear casein kinase and cyclin dependent kinase substrate 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:2,157,109...2,188,543
Ensembl chr38:2,160,233...2,170,560 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:55,821,227...55,857,597
Ensembl chr  X:55,821,234...55,855,502 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 ISO RGD PMID:12941932 RGD:1625241 NCBI chr24:36,936,469...37,010,929
Ensembl chr24:36,936,298...37,003,720 		JBrowse link
G RARRES2 retinoic acid receptor responder 2 involved_in ISO (PMID:18242188) UniProt PMID:18242188 NCBI chr16:14,671,345...14,675,000
Ensembl chr16:14,671,130...14,674,926 		JBrowse link
G SESN3 sestrin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:5,827,957...5,899,540
Ensembl chr21:5,777,780...5,892,805 		JBrowse link
G SIK2 salt inducible kinase 2 involved_in ISO (PMID:12624099) UniProt PMID:12624099 NCBI chr 5:21,354,127...21,479,891
Ensembl chr 5:21,358,902...21,479,841 		JBrowse link
G TSC2 TSC complex subunit 2 acts_upstream_of_or_within ISO (PMID:12403809) MGI PMID:12403809 NCBI chr 6:38,865,509...38,898,977
Ensembl chr 6:38,865,507...38,898,960 		JBrowse link
G VWA2 von Willebrand factor A domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:25,089,499...25,136,879
Ensembl chr28:25,089,499...25,136,893 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22100
    response to stimulus 9560
      response to endogenous stimulus 2003
        response to hormone 1316
          response to peptide hormone 673
            response to insulin 389
              cellular response to insulin stimulus 289
                glucose import in response to insulin stimulus 6
                insulin receptor signaling pathway + 157
                negative regulation of cellular response to insulin stimulus + 57
                positive regulation of cellular response to insulin stimulus + 35
                regulation of cellular response to insulin stimulus + 94
paths to the root