INSIG1 (insulin induced gene 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: INSIG1 (insulin induced gene 1) Canis lupus familiaris
Analyze
Symbol: INSIG1
Name: insulin induced gene 1
RGD ID: 12264445
Description: ENCODES a protein that exhibits oxysterol binding (inferred); INVOLVED IN cellular response to insulin stimulus (ortholog); cellular response to sterol (ortholog); cholesterol biosynthetic process (ortholog); PARTICIPATES IN sterol regulatory element-binding protein signaling pathway; ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); autistic disorder (ortholog); carcinoma (ortholog); FOUND IN endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: insulin-induced gene 1 protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11618,260,456 - 18,271,855 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1618,259,935 - 18,271,378 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1618,893,073 - 18,904,493 (+)NCBI
ROS_Cfam_1.01619,989,109 - 20,000,531 (+)NCBI
UMICH_Zoey_3.11618,359,941 - 18,371,370 (+)NCBI
UNSW_CanFamBas_1.01618,939,908 - 18,951,331 (+)NCBI
UU_Cfam_GSD_1.01618,992,903 - 19,004,326 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
INSIG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11618,260,456 - 18,271,855 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1618,259,935 - 18,271,378 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1618,893,073 - 18,904,493 (+)NCBI
ROS_Cfam_1.01619,989,109 - 20,000,531 (+)NCBI
UMICH_Zoey_3.11618,359,941 - 18,371,370 (+)NCBI
UNSW_CanFamBas_1.01618,939,908 - 18,951,331 (+)NCBI
UU_Cfam_GSD_1.01618,992,903 - 19,004,326 (+)NCBI
INSIG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7155,297,776 - 155,310,235 (+)EnsemblGRCh38hg38GRCh38
GRCh387155,297,878 - 155,310,235 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377155,089,588 - 155,101,945 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367154,720,476 - 154,732,879 (+)NCBINCBI36hg18NCBI36
Build 347154,527,190 - 154,539,592NCBI
Celera7149,506,354 - 149,518,817 (+)NCBI
Cytogenetic Map7q36.3NCBI
HuRef7148,822,074 - 148,834,485 (+)NCBIHuRef
CHM1_17155,097,819 - 155,110,278 (+)NCBICHM1_1
CRA_TCAGchr7v27154,316,806 - 154,329,270 (+)NCBI
Insig1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39528,276,410 - 28,283,660 (+)NCBIGRCm39mm39
GRCm39 Ensembl528,276,361 - 28,283,660 (+)Ensembl
GRCm38528,071,412 - 28,078,662 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl528,071,363 - 28,078,662 (+)EnsemblGRCm38mm10GRCm38
MGSCv37528,397,952 - 28,405,202 (+)NCBIGRCm37mm9NCBIm37
MGSCv36528,402,154 - 28,409,448 (+)NCBImm8
Celera525,621,532 - 25,628,781 (+)NCBICelera
Cytogenetic Map5B1NCBI
Insig1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.247,315,494 - 7,323,972 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl47,315,495 - 7,323,952 (-)Ensembl
Rnor_6.04342,302 - 350,515 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4342,302 - 350,515 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04337,389 - 345,602 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.442,577,468 - 2,585,682 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.142,577,467 - 2,585,682 (-)NCBI
Celera42,956,778 - 2,964,992 (+)NCBICelera
Cytogenetic Map4q11NCBI
Insig1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554918,335,359 - 8,344,658 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554918,333,624 - 8,344,658 (+)NCBIChiLan1.0ChiLan1.0
INSIG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17158,619,531 - 158,632,012 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7158,619,531 - 158,632,012 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v07146,893,730 - 146,906,329 (+)NCBIMhudiblu_PPA_v0panPan3
Insig1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051183,206,479 - 3,219,125 (-)NCBI
SpeTri2.0NW_0049365279,684,304 - 9,696,951 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
INSIG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl182,885,611 - 2,898,767 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1182,885,494 - 2,898,758 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2182,896,505 - 3,019,640 (-)NCBISscrofa10.2Sscrofa10.2susScr3
INSIG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121123,448,614 - 123,460,778 (+)NCBI
ChlSab1.1 Ensembl21123,449,106 - 123,460,807 (+)Ensembl
Vero_WHO_p1.0NW_02366607219,570,201 - 19,582,375 (+)NCBI
Insig1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248002,533,010 - 2,543,754 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 3 22 6 6 6 12 10 6
Low 1 2 6 6 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000008171   ⟹   ENSCAFP00000007569
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1618,261,060 - 18,271,378 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000059608   ⟹   ENSCAFP00000061892
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1618,259,935 - 18,270,250 (+)Ensembl
RefSeq Acc Id: XM_005629705   ⟹   XP_005629762
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11618,260,456 - 18,271,855 (+)NCBI
Dog10K_Boxer_Tasha1618,893,098 - 18,904,493 (+)NCBI
Sequence:
RefSeq Acc Id: XM_022403900   ⟹   XP_022259608
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11618,260,478 - 18,271,855 (+)NCBI
Dog10K_Boxer_Tasha1618,893,073 - 18,904,493 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038497383   ⟹   XP_038353311
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11618,359,966 - 18,371,370 (+)NCBI
RefSeq Acc Id: XM_038497384   ⟹   XP_038353312
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11618,359,941 - 18,371,370 (+)NCBI
RefSeq Acc Id: XM_038559803   ⟹   XP_038415731
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01618,992,925 - 19,004,326 (+)NCBI
RefSeq Acc Id: XM_038559804   ⟹   XP_038415732
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01618,992,903 - 19,004,326 (+)NCBI
RefSeq Acc Id: XM_038623807   ⟹   XP_038479735
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01618,939,931 - 18,951,331 (+)NCBI
RefSeq Acc Id: XM_038623808   ⟹   XP_038479736
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01618,939,908 - 18,951,331 (+)NCBI
RefSeq Acc Id: XM_038689572   ⟹   XP_038545500
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01619,989,132 - 20,000,531 (+)NCBI
RefSeq Acc Id: XM_038689573   ⟹   XP_038545501
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01619,989,109 - 20,000,531 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_005629762   ⟸   XM_005629705
- Peptide Label: isoform X1
- UniProtKB: E2RJ47 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022259608   ⟸   XM_022403900
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCAFP00000061892   ⟸   ENSCAFT00000059608
RefSeq Acc Id: ENSCAFP00000007569   ⟸   ENSCAFT00000008171
RefSeq Acc Id: XP_038353312   ⟸   XM_038497384
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038353311   ⟸   XM_038497383
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038479736   ⟸   XM_038623808
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038479735   ⟸   XM_038623807
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038545501   ⟸   XM_038689573
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038545500   ⟸   XM_038689572
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038415732   ⟸   XM_038559804
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038415731   ⟸   XM_038559803
- Peptide Label: isoform X1

Promoters
RGD ID:13686072
Promoter ID:EPDNEW_C4140
Type:initiation region
Name:INSIG1_1
Description:insulin induced gene 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11618,260,443 - 18,260,503EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000005081 Ensembl, ENTREZGENE
Ensembl Protein ENSCAFP00000061892 ENTREZGENE
NCBI Gene INSIG1 ENTREZGENE
UniProt E2RJ47 ENTREZGENE
VGNC ID VGNC:42039 ENTREZGENE