Gene: MAPK1 (mitogen-activated protein kinase 1) Canis lupus familiaris
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Symbol:
MAPK1
Name:
mitogen-activated protein kinase 1
Description:
ENCODES a protein that exhibits ATP binding (inferred); identical protein binding (inferred); MAP kinase kinase activity (inferred); INVOLVED IN activation of MAPK activity (inferred); B cell receptor signaling pathway (inferred); Bergmann glial cell differentiation (inferred); PARTICIPATES IN acute myeloid leukemia pathway; adenosine signaling pathway; aldosterone signaling pathway; ASSOCIATED WITH Aberrant Crypt Foci (ortholog); Alzheimer's disease (ortholog); Animal Disease Models (ortholog); FOUND IN cell (inferred); cytosol (inferred); mitochondrion (inferred); INTERACTS WITH arsane; arsenic atom; arsenous acid
Type:
protein-coding
RefSeq Status:
INFERRED
Also known as:
ERK2
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
MAPK1 (mitogen-activated protein kinase 1) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Mapk1 (mitogen-activated protein kinase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):
Mapk1 (mitogen activated protein kinase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Mapk1 (mitogen-activated protein kinase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
MAPK1 (mitogen-activated protein kinase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Mapk1 (mitogen-activated protein kinase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
MAPK1 (mitogen-activated protein kinase 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
MAPK3 (mitogen-activated protein kinase 3) HGNC
OrthoDB, OrthoMCL
Latest Assembly:
CanFam3.1 - Dog CanFam3.1 Assembly
Position:
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
RGD Manual Annotations
Aberrant Crypt Foci ISS RGD:8945135 9068941 RGD PMID:23467982 , REF_RGD_ID:13210776 Alzheimer's disease treatment ISS RGD:8945135 9068941 RGD PMID:28079060 , REF_RGD_ID:13800563 Alzheimer's disease onset ISS RGD:8945135 9068941 mRNA:increased expression: CA2 field of hippocampus, pyramidal neuron RGD PMID:24334724 , REF_RGD_ID:13800868 brain ischemia ISS RGD:8945135 9068941 RGD PMID:15669185 , REF_RGD_ID:1582281 breast cancer ISS RGD:8945135 9068941 protein:increased expression, increased phosphorylation:breast RGD PMID:15928662 , REF_RGD_ID:2314939 Cardiomegaly ISS RGD:8945135 9068941 RGD PMID:15607907 , REF_RGD_ID:1582283 childhood pilocytic astrocytoma ISS RGD:8945135 9068941 protein:increased expression:brain: RGD PMID:21466243 , REF_RGD_ID:13702864 colon adenocarcinoma ISS RGD:8945135 9068941 RGD PMID:24691442 , REF_RGD_ID:13210775 colorectal adenocarcinoma treatment ISS RGD:8945135 9068941 RGD PMID:25405740 , REF_RGD_ID:13210782 Colorectal Neoplasms ISS RGD:8945135 9068941 RGD PMID:10323886 , REF_RGD_ID:13210794 coronary restenosis ISS RGD:8945135 9068941 RGD PMID:15583728 , REF_RGD_ID:1582284 demyelinating disease ISS RGD:8945135 9068941 RGD PMID:27596241 , REF_RGD_ID:13800879 Diabetes Mellitus, Experimental ISS RGD:8945135 9068941 protein:decreased phosphorylation:cornea RGD PMID:21330660 , REF_RGD_ID:5131482 Diabetes Mellitus, Experimental ISS RGD:8945135 9068941 RGD PMID:22045654 , REF_RGD_ID:7243969 Diabetic Cardiomyopathies treatment ISS RGD:8945135 9068941 associated with Diabetes Mellitus, Experimental RGD PMID:25907942 , REF_RGD_ID:13800893 Diabetic Nephropathies ISS RGD:8945135 9068941 RGD PMID:19923143 , REF_RGD_ID:7243957 endometrial adenocarcinoma treatment ISS RGD:8945135 9068941 human tumor in a mouse model RGD PMID:23402905 , REF_RGD_ID:13703125 endometrial adenocarcinoma ISS RGD:8945135 9068941 protein:decreased phosphorylation:endometrium (human) RGD PMID:14760076 , REF_RGD_ID:13703137 endometrial carcinoma severity ISS RGD:8945135 9068941 protein:increased phosphorylation:endometrium (human) RGD PMID:22459351 , REF_RGD_ID:13441552 endometrial carcinoma ISS RGD:8945135 9068941 protein:increased expression:endometrium (human) RGD PMID:29081408 , REF_RGD_ID:13702082 Endometrioid Carcinomas treatment ISS RGD:8945135 9068941 RGD PMID:24917306 , REF_RGD_ID:13441559 Experimental Colitis treatment ISS RGD:8945135 9068941 RGD PMID:27028006 , REF_RGD_ID:13800882 Experimental Liver Cirrhosis treatment ISS RGD:8945135 9068941 RGD PMID:27396351 , REF_RGD_ID:13800880 gastric ulcer ISS RGD:8945135 9068941 RGD PMID:25518106 , REF_RGD_ID:13800896 glomerulonephritis ISS RGD:8945135 9068941 RGD PMID:20203158 , REF_RGD_ID:7243972 Hemorrhagic Shock ISS RGD:8945135 9068941 protein: increased expression: lung and liver RGD PMID:22392145 , REF_RGD_ID:7244173 kidney disease ISS RGD:8945135 9068941 RGD PMID:15213271 , REF_RGD_ID:7243971 Mammary Neoplasms, Experimental treatment ISS RGD:8945135 9068941 RGD PMID:29435821 , REF_RGD_ID:13800872 middle cerebral artery infarction treatment ISS RGD:8945135 9068941 RGD PMID:27152455 , REF_RGD_ID:13800881 Multiple Organ Failure ISS RGD:8945135 9068941 protein: increased expression: lung and liver RGD PMID:22392145 , REF_RGD_ID:7244173 myocardial infarction ISS RGD:8945135 9068941 RGD PMID:15653762 , REF_RGD_ID:1582282 Myocardial Reperfusion Injury treatment ISS RGD:8945135 9068941 RGD PMID:25345742 , REF_RGD_ID:13800900 Myocardial Reperfusion Injury ISS RGD:8945135 9068941 RGD PMID:15653762 , REF_RGD_ID:1582282 Neoplasm Metastasis treatment ISS RGD:8945135 9068941 associated with prostate adenocarcinoma RGD PMID:22139534 , REF_RGD_ID:13504820 obesity ISS RGD:8945135 9068941 protein:increased phosphorylation:endometrium (human) RGD PMID:20074784 , REF_RGD_ID:13782055 pancreatic adenocarcinoma severity ISS RGD:8945135 9068941 mRNA:increased expression:pancreas (human) RGD PMID:27919956 , REF_RGD_ID:13451128 prostate adenocarcinoma treatment ISS RGD:8945135 9068941 RGD PMID:28492138 , REF_RGD_ID:13504818 prostate adenocarcinoma treatment ISS RGD:8945135 9068941 RGD PMID:22139534 , REF_RGD_ID:13504820 pulmonary hypertension treatment ISS RGD:8945135 9068941 RGD PMID:25907942 , REF_RGD_ID:13800893 renal cell carcinoma susceptibility ISS RGD:8945135 9068941 DNA:missense mutation: :multiple RGD PMID:22517515 , REF_RGD_ID:13504815 renal fibrosis ISS RGD:8945135 9068941 RGD PMID:23698112 , REF_RGD_ID:7244171 Shock treatment ISS RGD:8945135 9068941 RGD PMID:29110153 , REF_RGD_ID:13800566 Testis Reperfusion Injury treatment ISS RGD:8945135 9068941 RGD PMID:15944243 , REF_RGD_ID:13800876 thyroid gland cancer disease_progression ISS RGD:8945135 9068941 mRNA, protein:increased expression RGD PMID:28992617 , REF_RGD_ID:13792721 type 2 diabetes mellitus ISS RGD:8945135 9068941 protein:increased expression:dorsal horn: RGD PMID:28757391 , REF_RGD_ID:13506777 type 2 diabetes mellitus ISS RGD:8945135 9068941 protein:hypophosphorylation:pancreatic islet: RGD PMID:21911753 , REF_RGD_ID:13506785 type 2 diabetes mellitus treatment ISS RGD:8945135 9068941 RGD PMID:19164460 , REF_RGD_ID:13506786 type 2 diabetes mellitus ISS RGD:8945135 9068941 protein:hyperphosphorylation:pancreas: RGD PMID:27259299 , REF_RGD_ID:13506776 type 2 diabetes mellitus treatment ISS RGD:8945135 9068941 RGD PMID:26860984 , REF_RGD_ID:13506775 ureteral obstruction treatment ISS RGD:8945135 9068941 RGD PMID:28063381 , REF_RGD_ID:13800569 urethral obstruction ISS RGD:8945135 9068941 RGD PMID:23698112 , REF_RGD_ID:7244171 Urinary Incontinence ISS RGD:8945135 9068941 RGD PMID:22950999 , REF_RGD_ID:7244159
Imported Annotations - ClinVar
chromosome 22q11.2 deletion syndrome, distal ISS RGD:8945135 9068941 ClinVar Annotator: match by term: Chromosome 22q11.2 deletion syndrome, distal ClinVar PMID:21681106 genetic disease ISS RGD:8945135 9068941 ClinVar Annotator: match by term: Inborn genetic diseases ClinVar head and neck squamous cell carcinoma ISS RGD:8945135 9068941 ClinVar Annotator: match by term: Squamous cell carcinoma of the head and neck ClinVar PMID:26619011 Multiple Abnormalities ISS RGD:8945135 9068941 ClinVar Annotator: match by term: Multiple congenital anomalies ClinVar transitional cell carcinoma ISS RGD:8945135 9068941 ClinVar Annotator: match by term: Transitional cell carcinoma of the bladder ClinVar PMID:26619011 Uterine Cervical Neoplasms ISS RGD:8945135 9068941 ClinVar Annotator: match by term: Uterine cervical neoplasms ClinVar PMID:26619011
Imported Annotations - CTD
Animal Disease Models ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:27093858 brain ischemia ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:17901229 cardiomyopathy ISS RGD:8945135 9068941 CTD Direct Evidence: therapeutic CTD PMID:10620750 Cocaine-Related Disorders ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:16407894 , PMID:20692647 Experimental Liver Neoplasms ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:28100771 extrahepatic cholestasis ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:28789951 Female Infertility ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:21177758 Gliosis ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:19402951 Head and Neck Neoplasms ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:15342401 Hyperalgesia ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:12941468 , PMID:27093858 Hypertrophy ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:12237323 juvenile rheumatoid arthritis ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:19565504 Kidney Neoplasms ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:21813464 Lung Neoplasms ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:11884234 , PMID:12376484 Neoplasm Invasiveness ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:22580338 Neoplasm Metastasis ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:22580338 Nerve Degeneration ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:19911010 neuronal ceroid lipofuscinosis 6 ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:23516525 Ovarian Neoplasms ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:16211241 Pneumococcal Pneumonia ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:24894820 Radiation Injuries, Experimental ISS RGD:8945135 9068941 CTD Direct Evidence: therapeutic CTD PMID:22247605 Sepsis ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:15489642 Sezary's disease ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:26551667 squamous cell carcinoma ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:21401805 Stomach Neoplasms ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:17003101 trigeminal neuralgia ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:27093858 withdrawal disorder ISS RGD:8945135 9068941 CTD Direct Evidence: marker/mechanism CTD PMID:17549049 Imported Annotations - MGI
autism spectrum disorder ISS RGD:8945135 9068941 MouseDO velocardiofacial syndrome ISS RGD:8945135 9068941 OMIM:192430 MouseDO Weissenbacher-Zweymuller syndrome ISS RGD:8945135 9068941 OMIM:261800 MouseDO
arsane increases phosphorylation EXP 6480464 Arsenic results in increased phosphorylation of MAPK1 protein CTD PMID:29306782 arsenic atom increases phosphorylation EXP 6480464 Arsenic results in increased phosphorylation of MAPK1 protein CTD PMID:29306782 arsenous acid multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK1 protein], Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:23236503 Colforsin dapropate hydrochloride multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Colforsin co-treated with INS protein] results in increased phosphorylation of MAPK1 protein], [Colforsin co-treated with INS protein] results in increased phosphorylation of MAPK1 protein CTD PMID:12639917 D-glucitol increases phosphorylation EXP 6480464 Sorbitol results in increased phosphorylation of MAPK1 protein CTD PMID:12639917 diarsenic trioxide multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK1 protein], Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK1 protein CTD PMID:23236503 glutathione multiple interactions EXP 6480464 Glutathione inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein], Glutathione inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK1 protein] CTD PMID:23816505 hydrogen peroxide multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] more ... CTD PMID:23816505 hydrogen peroxide increases phosphorylation EXP 6480464 Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein CTD PMID:23816505 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein], Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK1 protein] CTD PMID:23816505 phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with INS protein] results in increased phosphorylation of MAPK1 protein], [Tetradecanoylphorbol Acetate co-treated with INS protein] results in increased phosphorylation of MAPK1 protein CTD PMID:12639917 sodium chloride increases phosphorylation EXP 6480464 Sodium Chloride results in increased phosphorylation of MAPK1 protein CTD PMID:23816505 sodium chloride multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK1 protein] more ... CTD PMID:23816505
Biological Process activation of MAPK activity IEA GO:0004708 13508589 GOC GO_REF:0000108 B cell receptor signaling pathway IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 Bergmann glial cell differentiation IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 cardiac neural crest cell development involved in heart development IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 cell surface receptor signaling pathway IBA MGI:MGI:1346858 more ... 13508589 (PMID:21873635) GO_Central PMID:21873635 cellular response to amino acid starvation IEA UniProtKB:P28482 , ensembl:ENSP0000021583213508589 Ensembl GO_REF:0000107 cellular response to cadmium ion IEA UniProtKB:P28482 , ensembl:ENSP0000021583213508589 Ensembl GO_REF:0000107 cellular response to DNA damage stimulus IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 cellular response to dopamine IEA UniProtKB:P28482 , ensembl:ENSP0000021583213508589 Ensembl GO_REF:0000107 cellular response to granulocyte macrophage colony-stimulating factor stimulus IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 cellular response to organic substance IBA PANTHER:PTN001172432 , RGD:70500 13508589 (PMID:21873635) GO_Central PMID:21873635 cellular response to reactive oxygen species IEA UniProtKB:P28482 , ensembl:ENSP0000021583213508589 Ensembl GO_REF:0000107 cellular response to tumor necrosis factor IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 cytosine metabolic process IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 ERBB signaling pathway IEA UniProtKB:P28482 , ensembl:ENSP0000021583213508589 Ensembl GO_REF:0000107 ERK1 and ERK2 cascade IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 ERK1 and ERK2 cascade IEA UniProtKB:P28482 , ensembl:ENSP0000021583213508589 Ensembl GO_REF:0000107 face development IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 intracellular signal transduction IBA CGD:CAL0000176774 more ... 13508589 (PMID:21873635) GO_Central PMID:21873635 labyrinthine layer blood vessel development IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 lipopolysaccharide-mediated signaling pathway IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 long-term synaptic potentiation IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 lung morphogenesis IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 mammary gland epithelial cell proliferation IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 negative regulation of cell differentiation IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 outer ear morphogenesis IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 peptidyl-serine phosphorylation IEA UniProtKB:P28482 , ensembl:ENSP0000021583213508589 Ensembl GO_REF:0000107 peptidyl-serine phosphorylation IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 peptidyl-threonine phosphorylation IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 positive regulation of gene expression IEA UniProtKB:P28482 , ensembl:ENSP0000021583213508589 Ensembl GO_REF:0000107 positive regulation of peptidyl-threonine phosphorylation IEA UniProtKB:P28482 , ensembl:ENSP0000021583213508589 Ensembl GO_REF:0000107 positive regulation of telomerase activity IEA UniProtKB:P28482 , ensembl:ENSP0000021583213508589 Ensembl GO_REF:0000107 positive regulation of telomere capping IEA UniProtKB:P28482 , ensembl:ENSP0000021583213508589 Ensembl GO_REF:0000107 positive regulation of telomere maintenance via telomerase IEA UniProtKB:P28482 , ensembl:ENSP0000021583213508589 Ensembl GO_REF:0000107 regulation of cellular pH IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 regulation of gene expression IBA FB:FBgn0000229 more ... 13508589 (PMID:21873635) GO_Central PMID:21873635 regulation of ossification IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 response to epidermal growth factor IEA UniProtKB:P28482 , ensembl:ENSP0000021583213508589 Ensembl GO_REF:0000107 response to exogenous dsRNA IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 response to nicotine IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 stress-activated MAPK cascade IEA UniProtKB:P28482 , ensembl:ENSP0000021583213508589 Ensembl GO_REF:0000107 T cell receptor signaling pathway IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 thymus development IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 thyroid gland development IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 trachea formation IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 Cellular Component cell IEA GO:0030641 13508589 GOC GO_REF:0000108 cytoplasm IBA CGD:CAL0000197240 more ... 13508589 (PMID:21873635) GO_Central PMID:21873635 cytosol IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 mitochondrion IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 nucleus IBA CGD:CAL0000197240 more ... 13508589 (PMID:21873635) GO_Central PMID:21873635 pseudopodium IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 Molecular Function ATP binding IEA UniProtKB-KW:KW-0067 13508589 UniProtKB GO_REF:0000038 identical protein binding IEA UniProtKB:P28482 , ensembl:ENSP0000021583213508589 Ensembl GO_REF:0000107 identical protein binding IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 MAP kinase activity IBA CGD:CAL0000183747 more ... 13508589 (PMID:21873635) GO_Central PMID:21873635 MAP kinase kinase activity IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 phosphatase binding IEA UniProtKB:P28482 , ensembl:ENSP0000021583213508589 Ensembl GO_REF:0000107 phosphatase binding IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 phosphotyrosine residue binding IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107 RNA polymerase II CTD heptapeptide repeat kinase activity IEA UniProtKB:P63085 , ensembl:ENSMUSP0000006598313508589 Ensembl GO_REF:0000107
Gene-Chemical Interaction Annotations
