CAV2 (caveolin 2) - Rat Genome Database

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Gene: CAV2 (caveolin 2) Canis lupus familiaris
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Symbol: CAV2
Name: caveolin 2
RGD ID: 12122096
Description: ENCODES a protein that exhibits D1 dopamine receptor binding (ortholog); mitogen-activated protein kinase kinase kinase binding (ortholog); phosphoprotein binding (ortholog); INVOLVED IN basement membrane organization (ortholog); caveola assembly (ortholog); chemical synaptic transmission (ortholog); PARTICIPATES IN reverse cholesterol transport pathway; syndecan signaling pathway; ASSOCIATED WITH atrial fibrillation (ortholog); Experimental Autoimmune Myocarditis (ortholog); high grade glioma (ortholog); FOUND IN caveola (ortholog); cell surface (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CAV-2; caveolin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11455,437,622 - 55,445,481 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1455,437,622 - 55,445,469 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1454,833,000 - 54,840,856 (+)NCBI
ROS_Cfam_1.01455,479,629 - 55,487,494 (+)NCBI
UMICH_Zoey_3.11455,507,542 - 55,515,378 (+)NCBI
UNSW_CanFamBas_1.01455,195,940 - 55,203,807 (+)NCBI
UU_Cfam_GSD_1.01455,567,047 - 55,574,903 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:9472032   PMID:12633858   PMID:12743374   PMID:12917688   PMID:15569306   PMID:15703204   PMID:18081315  


Genomics

Comparative Map Data
CAV2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11455,437,622 - 55,445,481 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1455,437,622 - 55,445,469 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1454,833,000 - 54,840,856 (+)NCBI
ROS_Cfam_1.01455,479,629 - 55,487,494 (+)NCBI
UMICH_Zoey_3.11455,507,542 - 55,515,378 (+)NCBI
UNSW_CanFamBas_1.01455,195,940 - 55,203,807 (+)NCBI
UU_Cfam_GSD_1.01455,567,047 - 55,574,903 (+)NCBI
CAV2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7116,287,380 - 116,508,541 (+)EnsemblGRCh38hg38GRCh38
GRCh387116,499,738 - 116,508,541 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377116,139,792 - 116,148,595 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367115,926,680 - 115,935,831 (+)NCBINCBI36hg18NCBI36
Build 347115,733,394 - 115,742,545NCBI
Celera7110,946,853 - 110,956,001 (+)NCBI
Cytogenetic Map7q31.2NCBI
HuRef7110,505,654 - 110,514,581 (+)NCBIHuRef
CHM1_17116,073,006 - 116,081,933 (+)NCBICHM1_1
CRA_TCAGchr7v27115,535,087 - 115,544,028 (+)NCBI
Cav2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39617,281,184 - 17,289,129 (+)NCBIGRCm39mm39
GRCm39 Ensembl617,281,184 - 17,289,114 (+)Ensembl
GRCm38617,281,185 - 17,289,130 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl617,281,185 - 17,289,115 (+)EnsemblGRCm38mm10GRCm38
MGSCv37617,231,341 - 17,239,011 (+)NCBIGRCm37mm9NCBIm37
MGSCv36617,231,341 - 17,239,011 (+)NCBImm8
Celera617,353,818 - 17,361,488 (+)NCBICelera
Cytogenetic Map6A2NCBI
Cav2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2445,616,766 - 45,624,144 (+)NCBI
Rnor_6.0 Ensembl444,573,264 - 44,580,638 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0444,573,264 - 44,580,640 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0445,178,080 - 45,186,997 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4442,932,127 - 42,939,503 (+)NCBIRGSC3.4rn4RGSC3.4
Celera440,892,754 - 40,900,130 (+)NCBICelera
Cytogenetic Map4q21NCBI
Cav2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543222,240,041 - 22,242,200 (+)NCBIChiLan1.0ChiLan1.0
CAV2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17120,951,568 - 121,177,415 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7121,168,579 - 121,177,415 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v07108,254,074 - 108,480,716 (+)NCBIMhudiblu_PPA_v0panPan3
Cav2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511844,128,741 - 44,135,934 (+)NCBI
SpeTri2.0NW_0049365892,553,932 - 2,561,186 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CAV2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1829,699,020 - 29,707,277 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11829,699,012 - 29,707,277 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21831,796,924 - 31,805,190 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CAV2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12185,197,452 - 85,206,521 (+)NCBI
ChlSab1.1 Ensembl2185,197,537 - 85,206,588 (+)Ensembl
Vero_WHO_p1.0NW_02366604218,527,200 - 18,536,233 (-)NCBI
Cav2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248272,897,824 - 2,905,835 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 5 14 6 6 6 12 10 6
Low 1 8 6 6 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000048990   ⟹   ENSCAFP00000038932
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1455,437,622 - 55,445,469 (+)Ensembl
RefSeq Acc Id: NM_001010997   ⟹   NP_001010997
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11455,437,622 - 55,445,477 (+)NCBI
Dog10K_Boxer_Tasha1454,833,000 - 54,840,856 (+)NCBI
ROS_Cfam_1.01455,479,629 - 55,487,493 (+)NCBI
UMICH_Zoey_3.11455,507,542 - 55,515,378 (+)NCBI
UNSW_CanFamBas_1.01455,195,940 - 55,203,807 (+)NCBI
UU_Cfam_GSD_1.01455,567,047 - 55,574,903 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005628348   ⟹   XP_005628405
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11455,437,849 - 55,445,481 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038685938   ⟹   XP_038541866
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01455,479,856 - 55,487,494 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001010997 (Get FASTA)   NCBI Sequence Viewer  
  XP_038541866 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB92672 (Get FASTA)   NCBI Sequence Viewer  
  AAR16265 (Get FASTA)   NCBI Sequence Viewer  
  O46550 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001010997   ⟸   NM_001010997
- UniProtKB: O46550 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005628405   ⟸   XM_005628348
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSCAFP00000038932   ⟸   ENSCAFT00000048990
RefSeq Acc Id: XP_038541866   ⟸   XM_038685938
- Peptide Label: isoform X1

Promoters
RGD ID:13685821
Promoter ID:EPDNEW_C3889
Type:initiation region
Name:CAV2_1
Description:caveolin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11455,437,886 - 55,437,946EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000003402 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSCAFG00030007499 UniProtKB/Swiss-Prot
  ENSCAFG00040016417 UniProtKB/Swiss-Prot
Ensembl Protein ENSCAFP00000038932 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSCAFP00030012051 UniProtKB/Swiss-Prot
  ENSCAFP00040026462 UniProtKB/Swiss-Prot
Ensembl Transcript ENSCAFT00000048990 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSCAFT00030013808 UniProtKB/Swiss-Prot
  ENSCAFT00040030363 UniProtKB/Swiss-Prot
InterPro CAV-2 UniProtKB/Swiss-Prot
  Caveolin UniProtKB/Swiss-Prot
  Caveolin_CS UniProtKB/Swiss-Prot
KEGG Report cfa:475294 UniProtKB/Swiss-Prot
NCBI Gene CAV2 ENTREZGENE
PANTHER PTHR10844 UniProtKB/Swiss-Prot
  PTHR10844:SF3 UniProtKB/Swiss-Prot
Pfam Caveolin UniProtKB/Swiss-Prot
PROSITE CAVEOLIN UniProtKB/Swiss-Prot
UniProt CAV2_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A0M8U7 UniProtKB/Swiss-Prot
VGNC ID VGNC:38752 ENTREZGENE