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Gene: SLC2A4 (solute carrier family 2 member 4) Canis lupus familiaris

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Symbol:

SLC2A4

Name:

solute carrier family 2 member 4

RGD ID:

12427738

Description:

ENCODES a protein that exhibits D-glucose transmembrane transporter activity (ortholog); D-glucose uniporter activity (ortholog); INVOLVED IN amylopectin biosynthetic process (ortholog); brown fat cell differentiation (ortholog); cellular response to hypoxia (ortholog); PARTICIPATES IN facilitative sugar transporter mediated glucose transport pathway; insulin responsive facilitative sugar transporter mediated glucose transport pathway; insulin signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Cardiomegaly (ortholog); common variable immunodeficiency (ortholog); FOUND IN cell surface (ortholog); clathrin-coated pit (ortholog); cytoplasmic vesicle membrane (ortholog)

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

glucose transporter type 4, insulin-responsive; GLUT-4; GLUT4; Insulin-responsive glucose transporter; solute carrier family 2, facilitated glucose transporter member 4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	32,238,095 - 32,244,022 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	32,238,095 - 32,244,021 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	32,376,140 - 32,382,065 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	32,343,488 - 32,349,420 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	32,342,566 - 32,350,065 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	32,308,943 - 32,314,868 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	32,267,746 - 32,273,663 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	32,444,733 - 32,450,658 (+)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

Cardiomegaly (ISO)

common variable immunodeficiency (ISO)

congenital myasthenic syndrome 2A (ISO)

congestive heart failure (ISO)

coronary artery disease (ISO)

dyskeratosis congenita (ISO)

Experimental Diabetes Mellitus (ISO)

Faundes-Banka Syndrome (ISO)

Insulin Resistance (ISO)

intellectual disability (ISO)

Li-Fraumeni syndrome (ISO)

maturity-onset diabetes of the young type 1 (ISO)

Metabolic Syndrome (ISO)

Myocardial Reperfusion Injury (ISO)

pulmonary hypertension (ISO)

type 2 diabetes mellitus (ISO)

very long chain acyl-CoA dehydrogenase deficiency (ISO)

Weissenbacher-Zweymuller syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

amylopectin biosynthetic process (IEA,ISO)

brown fat cell differentiation (IEA,ISO)

cellular response to hypoxia (ISO)

cellular response to insulin stimulus (IEA,ISO)

cellular response to osmotic stress (IEA,ISO)

cellular response to tumor necrosis factor (IEA,ISO)

D-glucose import (ISO)

D-glucose transmembrane transport (IEA,ISO,ISS)

glucose homeostasis (IEA,ISO)

glucose import in response to insulin stimulus (IEA,ISO,ISS)

learning or memory (ISO)

long-term memory (ISO)

positive regulation of brain-derived neurotrophic factor receptor signaling pathway (ISO)

regulation of synaptic vesicle budding from presynaptic endocytic zone membrane (ISO)

response to ethanol (ISO)

short-term memory (ISO)

transmembrane transport (IEA)

Cellular Component

cell surface (ISO)

clathrin-coated pit (ISO)

clathrin-coated vesicle (IEA)

cytoplasm (IEA)

cytoplasmic vesicle membrane (IEA,ISS)

cytosol (IEA)

endomembrane system (IEA,ISS)

endosome (IEA,ISO)

external side of plasma membrane (IEA)

extracellular exosome (IEA)

insulin-responsive compartment (IEA,ISO,ISS)

membrane (IEA)

membrane raft (IEA)

multivesicular body (ISO)

perinuclear region of cytoplasm (IEA,ISO,ISS)

plasma membrane (IEA,ISO,ISS)

presynapse (ISO)

sarcolemma (IEA,ISO)

sarcoplasmic reticulum (ISO)

T-tubule (ISO)

trans-Golgi network (IEA)

trans-Golgi network transport vesicle (IEA)

vesicle (ISO)

vesicle membrane (IEA)

Molecular Function

D-glucose transmembrane transporter activity (IEA,ISO,ISS)

D-glucose uniporter activity (ISS)

hexose transmembrane transporter activity (IEA)

protein binding (ISO)

transmembrane transporter activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

facilitative sugar transporter mediated glucose transport pathway (ISO)

insulin responsive facilitative sugar transporter mediated glucose transport pathway (ISO)

insulin signaling pathway (ISO)

phosphatidylinositol 3-kinase-Akt signaling pathway (ISO)

References

Additional References at PubMed

PMID:10964405	PMID:18535164	PMID:21849635	PMID:22301074	PMID:23111893	PMID:25236492	PMID:30032202

Genomics

Comparative Map Data

SLC2A4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	32,238,095 - 32,244,022 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	32,238,095 - 32,244,021 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	32,376,140 - 32,382,065 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	32,343,488 - 32,349,420 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	32,342,566 - 32,350,065 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	32,308,943 - 32,314,868 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	32,267,746 - 32,273,663 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	32,444,733 - 32,450,658 (+)	NCBI		UU_Cfam_GSD_1.0

SLC2A4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	7,281,718 - 7,288,257 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	7,281,718 - 7,288,257 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	7,185,037 - 7,191,576 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	7,125,778 - 7,132,091 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	7,125,834 - 7,131,125	NCBI
Celera	17	7,209,701 - 7,216,014 (+)	NCBI		Celera
Cytogenetic Map	17	p13.1	NCBI
HuRef	17	7,076,412 - 7,082,727 (+)	NCBI		HuRef
CHM1_1	17	7,193,837 - 7,200,150 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	7,182,662 - 7,189,200 (+)	NCBI		T2T-CHM13v2.0

Slc2a4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	69,833,112 - 69,839,040 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	69,833,365 - 69,839,014 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	69,942,286 - 69,948,216 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	69,942,539 - 69,948,188 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	69,755,788 - 69,761,692 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	69,758,738 - 69,764,329 (-)	NCBI		MGSCv36	mm8
Celera	11	77,490,257 - 77,496,161 (-)	NCBI		Celera
Cytogenetic Map	11	B3	NCBI
cM Map	11	42.93	NCBI

Slc2a4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	55,164,721 - 55,170,289 (-)	NCBI		GRCr8
mRatBN7.2	10	54,666,015 - 54,671,581 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	54,666,015 - 54,671,565 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	59,328,590 - 59,334,093 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	58,817,163 - 58,822,666 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	54,324,426 - 54,329,928 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	56,552,921 - 56,558,562 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	56,552,983 - 56,558,487 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	56,298,102 - 56,303,687 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	56,786,705 - 56,792,209 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	56,800,327 - 56,805,832 (-)	NCBI
Celera	10	53,819,953 - 53,825,446 (-)	NCBI		Celera
Cytogenetic Map	10	q24	NCBI

Slc2a4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955467	9,630,304 - 9,636,005 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955467	9,630,304 - 9,636,005 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLC2A4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	14,875,384 - 14,882,068 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	16,841,235 - 16,847,919 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	7,312,605 - 7,319,430 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	7,299,966 - 7,306,344 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	7,299,966 - 7,306,344 (+)	Ensembl	panpan1.1		panPan2

Slc2a4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	47,093,063 - 47,099,869 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936595	567,219 - 574,059 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936595	567,267 - 574,051 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC2A4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	52,628,450 - 52,634,967 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	52,628,746 - 52,634,965 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	54,810,360 - 54,816,580 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC2A4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	6,654,626 - 6,660,640 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	6,654,608 - 6,661,495 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666059	14,750,453 - 14,756,535 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc2a4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624786	9,902,509 - 9,909,684 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624786	9,903,176 - 9,908,953 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in SLC2A4
45 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	33	22	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001159327	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005619478	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038664061	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038664062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AJ388533	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CX007098	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CX008986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DN374469	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DN428922	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FJ797639	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000371	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000025579 ⟹ ENSCAFP00000023753

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	32,238,095 - 32,244,021 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000074884 ⟹ ENSCAFP00000063562

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	32,238,938 - 32,241,924 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845036596 ⟹ ENSCAFP00845028640

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	5	32,342,566 - 32,350,065 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845036689 ⟹ ENSCAFP00845028720

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	5	32,342,566 - 32,349,413 (+)	Ensembl

RefSeq Acc Id:

NM_001159327 ⟹ NP_001152799

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	5	32,238,095 - 32,244,022 (+)	NCBI
Dog10K_Boxer_Tasha	5	32,376,140 - 32,382,065 (+)	NCBI
ROS_Cfam_1.0	5	32,343,488 - 32,349,420 (+)	NCBI
UMICH_Zoey_3.1	5	32,308,943 - 32,314,868 (+)	NCBI
UNSW_CanFamBas_1.0	5	32,267,746 - 32,273,663 (+)	NCBI
UU_Cfam_GSD_1.0	5	32,444,733 - 32,450,658 (+)	NCBI

Sequence:

show sequence

GCCAGATCCCCCGGAGCCCAGCCGCTCTCTGGATCCTTGGCCCGCGACAGTGGGTCCCGCCAGG
CTCGCCCTCCGCACGCCGCTCCAGGACGCCCGGCGCCCCCGCGCCCTTTGCCCGCCAGGCCCGG
GCCGCGGACCTCGCAGTCGCCTCCCTGTTAACCGCGGTCCCTGCGCATCGGGTCCCTAAGACAA
GATGCCGTCGGGCTTCCAGCAGATCGGCTCGGAAGACGGGGAACCCCCTCAGCAGCGAGTCACT
GGGACCCTGGTCCTTGCCGTGTTCTCTGCTGTGCTCGGCTCCCTGCAGTTTGGCTATAACATCG
GAGTCATTAATGCGCCACAGAAGGTGATTGAACAGAGCTACAATGAGACATGGCTGGGGAGGCA
GGGGCCCCAGGGGCCCAGCTCCATTCCACCGGGCACCCTCACCACTCTCTGGGCTCTCTCAGTG
GCCATCTTTTCTGTGGGTGGCATGATCTCCTCCTTCCTCATTGGCATCATCTCTCAGTGGCTGG
GAAGGAAGAGGGCAATGCTGGTCAACAACGTCCTGGCGGTGCTGGGGGGTGCCCTCATGGGCCT
GGCCCATGCTGCTGCCTCCTACGAGATGCTCATTCTTGGGCGGTTCCTCATTGGCGCCTACTCA
GGGCTCACATCGGGGCTGGTGCCCATGTACGTGGGGGAGATCGCCCCCACTCACCTGCGGGGCG
CCTTGGGGACACTCAACCAACTGGCCATCGTCATTGGCATTCTGATCGCCCAGGTGCTGGGCTT
AGAGTCCATGCTGGGCACTACCACCCTATGGCCACTCCTCCTGGGCATCACAGTGCTGCCTGCC
CTCCTGCAGCTGGTCCTGCTGCCCTTCTGCCCAGAGAGCCCTCGCTACCTCTACATAATCCGGA
ACCTAGAGGGGCCTGCCAGAAAGAGTCTGAAGCGCCTGACCGGCTGGGCTGATGTATCTGGGGC
ACTGGCTGAGCTGAAGGAGGAGAAGCGGAAGCTGGAGCGGGAGCGGCCCCTGTCCCTGCTACAG
CTCCTGGGCAGCCGCACCCACCGGCAGCCTCTGGTCATCGCTGTCGTGCTGCAGCTGAGCCAGC
AGCTGTCAGGCATCAATGCCGTTTTCTATTATTCAACCAGCATCTTCGAGACGGCAGGGGTCGG
GCAGCCAGCCTATGCGACCATAGGAGCTGGTGTGGTCAACACAGTCTTCACCTTGGTCTCGGTG
TTCCTGGTCGAGCGGGCTGGCCGTCGGACACTCCATCTCCTGGGCCTGGCAGGAATGTGTGGCT
GTGCCATCTTGATGACCATAGCCCTGCTTCTGCTGGAGCGGCTTCCAGCCATGAGCTACGTCTC
CATCGTGGCCATCTTTGGCTTTGTGGCCTTCTTTGAGATTGGCCCAGGCCCCATTCCCTGGTTC
ATCGTGGCCGAGCTGTTCAGCCAGGGCCCCCGCCCAGCCGCCATGGCCGTGGCTGGCTTCTGCA
ACTGGACAAGCAACTTCATCATTGGCATGGGTTTCCAGTATATCGCGGAGGCCATGGGGCCCTA
TGTCTTCCTTCTGTTCGCGGTTCTCCTGCTCGCCTTCTTCATCTTCACCTTCCTAAAAGTGCCT
GAAACCCGAGGCCGGACTTTTGACCAGATCTCGGCTGACTTCCGCCGGACACCGTCTCTTCTAG
AGCAGGAGGTGAAGCCCAGCACGGAACTCGATTACTTAGGACCTGACGACGAGAATGACTGAGG
GGCCAGGGCAGGGGTGGGAGGGCTATGCTCTCGTCCCCCCCCCCCACCGCCCCCCACCGGAGAC
CTCTCCTATGCAGCACTTTTGCCCTCTCTTCCCTGTTACTTCCTGATGGAACTGGGAAGCCGGA
GGGAAGGGTGGTCTCAGCACCCCCTCATTCCCCTCGTGTGACTCTTGGATTATTTATGTGTCAT
GGTTAGGCTGTGGCCATCAGGGTGGACCACTCTGGCCACTCATCCCCTTCCTCCTCTGTAGCCC
ACCCCACCCGCACCCGGCCTCAGCTCCAGAATATTCTCGCCCCTCGCTAGAGAAGGGGGCTGCA
GGGAGGAGAGGCCCTAGGGCCGACTCTTTGGTCAGGGAGCAGGACCGGTGAAGACAAACAGCTT
CCTGCCACCTTGGGCTCCTCCTACTTTCTGGCACTTTCTCTGAATTCTTGCCACATAGACTCTG
GGTGAAGGGGGTCCCGTCTTGACCCCTGACAGGCCGCACCTCCCAAGGCCTCAGTTCACTCCTC
CTGGCAGGCTCAGCCCTCTCGCTCAACTGGAGGGCCATATGCCCATGCAAGGGGAGAGGGCCTG
CTCCCCCAGGCCGCAGAGGGGGAGCCCCGCTCTTGTCCCCTCGCCCCTCCTGAAGGGTGTGCCG
CCCGCAAGCTTTTGACCAACTAAGGGAAAGGAGGATTTGAAAGGCTGCCTGTAAACACGGGGTA
GGAGGAGCCTTCAGATATTTTTGTATATGTTTGCAAAAGGGGTGGGGAGAAGAAACCAAAGGTC
TGTTGTACTAAATGTATATATGTATGTATAGATGGATATATAAAGTCACTGTACGTGATGGCAA
AAAAAAA

hide sequence

RefSeq Acc Id:

XM_038664061 ⟹ XP_038519989

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	5	32,344,424 - 32,349,420 (+)	NCBI

RefSeq Acc Id:

XM_038664062 ⟹ XP_038519990

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	5	32,345,405 - 32,349,420 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001152799	(Get FASTA)	NCBI Sequence Viewer
	XP_038519989	(Get FASTA)	NCBI Sequence Viewer
	XP_038519990	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ACO34817	(Get FASTA)	NCBI Sequence Viewer
	CAB46835	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000023753.3
	ENSCAFP00030020294.1
	ENSCAFP00040006783.1
	ENSCAFP00845028640.1
	ENSCAFP00845028720
	ENSCAFP00845028720.1
GenBank Protein	Q9XST2	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001152799 ⟸ NM_001159327

- UniProtKB:

A0A8C0Q762 (UniProtKB/TrEMBL), A0A8I3PA13 (UniProtKB/TrEMBL), A0A8C0K899 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MPSGFQQIGSEDGEPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQ
GPQGPSSIPPGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGALMGL
AHAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGL
ESMLGTTTLWPLLLGITVLPALLQLVLLPFCPESPRYLYIIRNLEGPARKSLKRLTGWADVSGA
LAELKEEKRKLERERPLSLLQLLGSRTHRQPLVIAVVLQLSQQLSGINAVFYYSTSIFETAGVG
QPAYATIGAGVVNTVFTLVSVFLVERAGRRTLHLLGLAGMCGCAILMTIALLLLERLPAMSYVS
IVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFCNWTSNFIIGMGFQYIAEAMGPY
VFLLFAVLLLAFFIFTFLKVPETRGRTFDQISADFRRTPSLLEQEVKPSTELDYLGPDDEND

hide sequence

Ensembl Acc Id:

ENSCAFP00000023753 ⟸ ENSCAFT00000025579

Ensembl Acc Id:

ENSCAFP00000063562 ⟸ ENSCAFT00000074884

RefSeq Acc Id:	XP_038519989 ⟸ XM_038664061
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0K899 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038519990 ⟸ XM_038664062
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0KB74 (UniProtKB/TrEMBL), A0A8C0QYG1 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845028640 ⟸ ENSCAFT00845036596

Ensembl Acc Id:

ENSCAFP00845028720 ⟸ ENSCAFT00845036689

Protein Domains

Major facilitator superfamily (MFS) profile

Promoters

RGD ID:

13683219

Promoter ID:

EPDNEW_C1288

Type:

single initiation site

Name:

SLC2A4_1

Description:

solute carrier family 2 member 4

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	5	32,238,098 - 32,238,158	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000016126	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030012532	UniProtKB/TrEMBL
	ENSCAFG00040004066	UniProtKB/TrEMBL
	ENSCAFG00845020724	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000025579.5	UniProtKB/TrEMBL
	ENSCAFT00030023268.1	UniProtKB/TrEMBL
	ENSCAFT00040007765.1	UniProtKB/TrEMBL
	ENSCAFT00845036596.1	UniProtKB/TrEMBL
	ENSCAFT00845036689	ENTREZGENE
	ENSCAFT00845036689.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1250.20	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Glc_transpt_4	UniProtKB/TrEMBL
	GLUT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MFS_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MFS_sugar_transport-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MFS_trans_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Sugar/inositol_transpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Sugar_transporter_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	cfa:403673	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	SLC2A4	ENTREZGENE
PANTHER	PTHR23503	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 4	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Sugar_tr	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	GLUCTRSPORT4	UniProtKB/TrEMBL
	SUGRTRNSPORT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	MFS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SUGAR_TRANSPORT_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SUGAR_TRANSPORT_2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF103473	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8C0K899	ENTREZGENE
	A0A8C0KB74	ENTREZGENE
	A0A8C0Q762	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0QYG1	ENTREZGENE
	A0A8I3PA13	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3PDC9_CANLF	UniProtKB/TrEMBL
	C1K5F5_CANLF	UniProtKB/TrEMBL
	GLUT4_CANLF	UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID	VGNC:53442	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - SMPDB

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

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Imported Annotations - SMPDB

Imported Annotations - PID (archival)