MTOR (mechanistic target of rapamycin kinase) - Rat Genome Database

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Gene: MTOR (mechanistic target of rapamycin kinase) Canis lupus familiaris
Analyze
Symbol: MTOR
Name: mechanistic target of rapamycin kinase
RGD ID: 12225589
Description: ENCODES a protein that exhibits protein domain specific binding (ortholog); protein kinase binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN brain development (ortholog); calcineurin-NFAT signaling cascade (ortholog); cardiac cell development (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-4 signaling pathway; mTOR signaling pathway; ASSOCIATED WITH acute kidney failure (ortholog); adenocarcinoma (ortholog); AIDS-Associated Nephropathy (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); dendrite (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FK506 binding protein 12-rapamycin associated protein 1; FRAP1; mechanistic target of rapamycin; serine/threonine-protein kinase mTOR
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1284,818,893 - 84,939,283 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl284,787,708 - 84,939,114 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha281,349,286 - 81,469,352 (+)NCBI
ROS_Cfam_1.0285,486,181 - 85,601,386 (+)NCBI
ROS_Cfam_1.0 Ensembl285,480,139 - 85,601,386 (+)Ensembl
UMICH_Zoey_3.1282,229,433 - 82,349,483 (+)NCBI
UNSW_CanFamBas_1.0283,231,190 - 83,351,242 (+)NCBI
UU_Cfam_GSD_1.0284,293,674 - 84,413,764 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acute kidney failure  (ISO)
adenocarcinoma  (ISO)
AIDS-Associated Nephropathy  (ISO)
autosomal dominant polycystic kidney disease  (ISO)
autosomal recessive polycystic kidney disease  (ISO)
Breast Neoplasms  (ISO)
Burns  (ISO)
Cardiomegaly  (ISO)
CEBALID Syndrome  (ISO)
Cerebral Hemorrhage  (ISO)
chondrosarcoma  (ISO)
Chronic Allograft Dysfunction  (ISO)
colon cancer  (ISO)
Colonic Neoplasms  (ISO)
Colorectal Neoplasms  (ISO)
complex cortical dysplasia with other brain malformations  (ISO)
congestive heart failure  (ISO)
crescentic glomerulonephritis  (ISO)
Diabetes Mellitus, New-Onset after Transplantation  (ISO)
Diabetic Nephropathies  (ISO)
Drug-Induced Dyskinesia  (ISO)
end stage renal disease  (ISO)
endocrine system disease  (ISO)
exocrine pancreatic insufficiency  (ISO)
Experimental Arthritis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
Familial Atrial Fibrillation 6  (ISO)
Focal Cortical Dysplasia of Taylor  (ISO)
gastric adenocarcinoma  (ISO)
genetic disease  (ISO)
glioblastoma  (ISO)
Hemimegalencephaly  (ISO)
Hemorrhagic Shock  (ISO)
hepatocellular carcinoma  (ISO)
Hepatomegaly  (ISO)
high grade glioma  (ISO)
Hyperalgesia  (ISO)
hypertension  (ISO)
Hypertriglyceridemia  (ISO)
idiopathic interstitial pneumonia  (ISO)
immunodeficiency 14  (ISO)
Inflammation  (ISO)
intellectual disability  (ISO)
interstitial cystitis  (ISO)
kidney angiomyolipoma  (ISO)
Left Ventricular Hypertrophy  (ISO)
Lung Injury  (ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
lung small cell carcinoma  (ISO)
lupus nephritis  (ISO)
Lymphatic Metastasis  (ISO)
Macrocephaly  (ISO)
Mammary Neoplasms, Experimental  (ISO)
mantle cell lymphoma  (ISO)
melanoma  (ISO)
Mesothelioma  (ISO)
middle cerebral artery infarction  (ISO)
muscular atrophy  (ISO)
Muscular Dystrophy, Animal  (ISO)
myocardial infarction  (ISO)
Neoplasm Metastasis  (ISO)
nephritis  (ISO)
obesity  (ISO)
osteoarthritis  (ISO)
Ovarian Neoplasms  (ISO)
pancreatic cancer  (ISO)
pancreatic carcinoma  (ISO)
papillary renal cell carcinoma  (ISO)
Parkinsonism  (ISO)
Peroxisome Biogenesis Disorder, Complementation Group K  (ISO)
polycystic kidney disease  (ISO)
portal hypertension  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
pulmonary fibrosis  (ISO)
pulmonary hypertension  (ISO)
renal carcinoma  (ISO)
renal cell carcinoma  (ISO)
Renal Cell Carcinoma 1  (ISO)
Retinal Neovascularization  (ISO)
Right Ventricular Hypertrophy  (ISO)
schizophrenia  (ISO)
sciatic neuropathy  (ISO)
Sepsis  (ISO)
skin melanoma  (ISO)
small cell carcinoma  (ISO)
Smith-Kingsmore Syndrome  (ISO)
Spinal Cord Injuries  (ISO)
Sporadic Papillary Renal Cell Carcinoma  (ISO)
status epilepticus  (ISO)
T-cell acute lymphoblastic leukemia  (ISO)
temporal lobe epilepsy  (ISO)
Temporomandibular Joint Disorders  (ISO)
toxic encephalopathy  (ISO)
transitional cell carcinoma  (ISO)
type 2 diabetes mellitus  (ISO)
ureteral obstruction  (ISO)
urinary bladder cancer  (ISO)
uterine cancer  (ISO)
Uterine Cervical Neoplasms  (ISO)
vascular dementia  (ISO)
visual epilepsy  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
'de novo' pyrimidine nucleobase biosynthetic process  (IEA)
behavioral response to pain  (IEA)
brain development  (ISO)
calcineurin-NFAT signaling cascade  (ISO)
cardiac cell development  (ISO)
cardiac muscle cell development  (IEA,ISO)
cardiac muscle contraction  (IEA,ISO)
cardiac muscle tissue development  (ISO)
cell projection organization  (ISO)
cellular response to amino acid starvation  (ISO)
cellular response to amino acid stimulus  (ISO)
cellular response to hypoxia  (IEA)
cellular response to leucine  (IEA)
cellular response to leucine starvation  (IEA)
cellular response to nutrient levels  (ISO)
cellular response to starvation  (ISO)
energy reserve metabolic process  (IEA,ISO)
germ cell development  (IEA,ISO)
heart morphogenesis  (IEA,ISO)
heart valve morphogenesis  (IEA,ISO)
inflammatory response  (IEA)
long-term memory  (ISO)
lysosome organization  (IEA)
macroautophagy  (ISO)
maternal process involved in female pregnancy  (ISO)
mRNA stabilization  (ISO)
multicellular organism growth  (IEA,ISO)
negative regulation of autophagy  (ISO)
negative regulation of calcineurin-NFAT signaling cascade  (IEA,ISO)
negative regulation of cell size  (IEA,ISO)
negative regulation of cholangiocyte apoptotic process  (ISO)
negative regulation of iodide transmembrane transport  (ISO)
negative regulation of macroautophagy  (IBA,IEA,ISO)
negative regulation of muscle atrophy  (ISO)
negative regulation of protein phosphorylation  (ISO)
negative regulation of protein ubiquitination  (ISO)
neuronal action potential  (IEA)
nucleus localization  (IEA)
oligodendrocyte differentiation  (ISO)
peptidyl-serine phosphorylation  (IEA,ISO)
peptidyl-threonine phosphorylation  (IEA,ISO)
phosphorylation  (IEA,ISO)
positive regulation of actin filament polymerization  (IEA,ISO)
positive regulation of cell death  (ISO)
positive regulation of cell growth involved in cardiac muscle cell development  (ISO)
positive regulation of cellular senescence  (ISO)
positive regulation of cholangiocyte proliferation  (ISO)
positive regulation of dendritic spine development  (ISO)
positive regulation of eating behavior  (ISO)
positive regulation of endothelial cell proliferation  (ISO)
positive regulation of epithelial to mesenchymal transition  (IEA)
positive regulation of gene expression  (ISO)
positive regulation of glial cell proliferation  (ISO)
positive regulation of granulosa cell proliferation  (ISO)
positive regulation of keratinocyte migration  (IEA)
positive regulation of lamellipodium assembly  (IEA,ISO)
positive regulation of lipid biosynthetic process  (IEA)
positive regulation of myotube differentiation  (IEA,ISO)
positive regulation of neurogenesis  (ISO)
positive regulation of neuron death  (ISO)
positive regulation of neuron maturation  (ISO)
positive regulation of neuron projection development  (ISO)
positive regulation of nitric oxide biosynthetic process  (ISO)
positive regulation of oligodendrocyte differentiation  (IEA,ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (IEA,ISO)
positive regulation of protein kinase B signaling  (ISO)
positive regulation of protein metabolic process  (IEA)
positive regulation of protein phosphorylation  (ISO)
positive regulation of sensory perception of pain  (ISO)
positive regulation of skeletal muscle hypertrophy  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of stress fiber assembly  (IEA,ISO)
positive regulation of transcription by RNA polymerase III  (IEA)
positive regulation of transcription of nucleolar large rRNA by RNA polymerase I  (IEA)
positive regulation of translation  (IEA,ISO)
positive regulation of wound healing, spreading of epidermal cells  (IEA)
post-embryonic development  (IEA,ISO)
protein autophosphorylation  (IEA,ISO)
protein phosphorylation  (IEA,ISO)
regulation of actin cytoskeleton organization  (ISO)
regulation of autophagy  (ISO)
regulation of brown fat cell differentiation  (ISO)
regulation of carbohydrate metabolic process  (ISO)
regulation of carbohydrate utilization  (ISO)
regulation of cell growth  (IEA)
regulation of cell size  (ISO)
regulation of cellular component organization  (IEA)
regulation of circadian rhythm  (ISO)
regulation of fatty acid beta-oxidation  (ISO)
regulation of glycogen biosynthetic process  (ISO)
regulation of GTPase activity  (IEA,ISO)
regulation of locomotor rhythm  (IEA)
regulation of membrane permeability  (IEA,ISO)
regulation of myelination  (IEA,ISO)
regulation of osteoclast differentiation  (IEA)
regulation of protein kinase activity  (IEA,ISO)
regulation of protein kinase B signaling  (IEA,ISO)
regulation of protein phosphorylation  (ISO)
regulation of response to food  (ISO)
regulation of translation at synapse, modulating synaptic transmission  (ISO)
response to activity  (ISO)
response to amino acid  (ISO)
response to cocaine  (ISO)
response to heat  (IEA)
response to insulin  (IEA,ISO)
response to morphine  (ISO)
response to nutrient  (IEA)
response to nutrient levels  (ISO)
ruffle organization  (IEA,ISO)
social behavior  (ISO)
spinal cord development  (ISO)
T-helper 1 cell lineage commitment  (IEA)
TOR signaling  (ISO)
TORC1 signaling  (IBA,IEA)
visual learning  (ISO)
voluntary musculoskeletal movement  (IEA,ISO)
wound healing  (ISO)

Cellular Component

References
Additional References at PubMed
PMID:21321942   PMID:22177999   PMID:22789858   PMID:24651621   PMID:30011343   PMID:30476726   PMID:33894879  


Genomics

Comparative Map Data
MTOR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1284,818,893 - 84,939,283 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl284,787,708 - 84,939,114 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha281,349,286 - 81,469,352 (+)NCBI
ROS_Cfam_1.0285,486,181 - 85,601,386 (+)NCBI
ROS_Cfam_1.0 Ensembl285,480,139 - 85,601,386 (+)Ensembl
UMICH_Zoey_3.1282,229,433 - 82,349,483 (+)NCBI
UNSW_CanFamBas_1.0283,231,190 - 83,351,242 (+)NCBI
UU_Cfam_GSD_1.0284,293,674 - 84,413,764 (+)NCBI
MTOR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38111,106,535 - 11,262,551 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl111,106,535 - 11,262,551 (-)EnsemblGRCh38hg38GRCh38
GRCh37111,166,592 - 11,322,608 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36111,089,179 - 11,245,153 (-)NCBINCBI36hg18NCBI36
Build 34111,100,857 - 11,256,830NCBI
Celera110,278,903 - 10,434,848 (-)NCBI
Cytogenetic Map1p36.22NCBI
HuRef110,317,883 - 10,473,910 (-)NCBIHuRef
CHM1_1111,154,542 - 11,310,885 (-)NCBICHM1_1
Mtor
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394148,533,039 - 148,642,142 (+)NCBIGRCm39mm39
GRCm39 Ensembl4148,533,068 - 148,642,140 (+)Ensembl
GRCm384148,448,582 - 148,557,685 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4148,448,611 - 148,557,683 (+)EnsemblGRCm38mm10GRCm38
MGSCv374147,822,691 - 147,931,794 (+)NCBIGRCm37mm9NCBIm37
MGSCv364147,292,407 - 147,401,483 (+)NCBImm8
Celera4150,709,332 - 150,819,308 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map478.76NCBI
Mtor
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25158,884,856 - 158,994,311 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl5158,884,804 - 158,994,311 (+)Ensembl
Rnor_6.05165,263,813 - 165,373,967 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5165,263,800 - 165,373,967 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05168,920,414 - 169,030,568 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45165,531,402 - 165,640,899 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15165,541,594 - 165,651,087 (+)NCBI
Celera5157,161,454 - 157,270,899 (+)NCBICelera
Cytogenetic Map5q36NCBI
Mtor
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554862,487,642 - 2,599,694 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554862,487,642 - 2,599,694 (+)NCBIChiLan1.0ChiLan1.0
MTOR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1111,093,765 - 11,249,841 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl111,093,765 - 11,249,841 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v019,871,700 - 10,028,704 (-)NCBIMhudiblu_PPA_v0panPan3
Mtor
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505834,333,597 - 34,457,567 (-)NCBI
SpeTri2.0NW_004936474158,376 - 282,310 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MTOR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl671,286,989 - 71,412,888 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1671,286,989 - 71,412,913 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2665,191,742 - 65,317,489 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MTOR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120120,522,667 - 120,678,988 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl20120,525,737 - 120,679,020 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605424,431,846 - 24,582,610 (+)NCBIVero_WHO_p1.0
Mtor
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248181,570,155 - 1,698,264 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4 5 16 2 6 3 12 8 10 6
Low 1 6 6 4 6 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000026412   ⟹   ENSCAFP00000024527
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl284,787,708 - 84,939,114 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000064130   ⟹   ENSCAFP00000044316
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl284,833,061 - 84,939,114 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000070228   ⟹   ENSCAFP00000065177
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl284,787,708 - 84,939,114 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000074234   ⟹   ENSCAFP00000048878
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl284,787,708 - 84,939,114 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000077589   ⟹   ENSCAFP00000054233
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl284,787,708 - 84,939,114 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000082268   ⟹   ENSCAFP00000063184
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl284,787,708 - 84,939,114 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000084601   ⟹   ENSCAFP00000047415
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl284,787,708 - 84,939,114 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845004530   ⟹   ENSCAFP00845003618
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl285,480,139 - 85,601,355 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845004565   ⟹   ENSCAFP00845003647
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl285,495,161 - 85,601,386 (+)Ensembl
RefSeq Acc Id: XM_005618003   ⟹   XP_005618060
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1284,818,893 - 84,939,283 (+)NCBI
Dog10K_Boxer_Tasha281,349,286 - 81,469,352 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038471116   ⟹   XP_038327044
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1282,229,433 - 82,349,483 (+)NCBI
RefSeq Acc Id: XM_038532031   ⟹   XP_038387959
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0284,293,674 - 84,413,764 (+)NCBI
RefSeq Acc Id: XM_038596294   ⟹   XP_038452222
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0283,231,190 - 83,351,242 (+)NCBI
RefSeq Acc Id: XM_038660368   ⟹   XP_038516296
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0285,486,181 - 85,601,386 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_005618060   ⟸   XM_005618003
- Peptide Label: isoform X5
- UniProtKB: E2R2L2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000044316   ⟸   ENSCAFT00000064130
RefSeq Acc Id: ENSCAFP00000048878   ⟸   ENSCAFT00000074234
RefSeq Acc Id: ENSCAFP00000065177   ⟸   ENSCAFT00000070228
RefSeq Acc Id: ENSCAFP00000047415   ⟸   ENSCAFT00000084601
RefSeq Acc Id: ENSCAFP00000054233   ⟸   ENSCAFT00000077589
RefSeq Acc Id: ENSCAFP00000063184   ⟸   ENSCAFT00000082268
RefSeq Acc Id: ENSCAFP00000024527   ⟸   ENSCAFT00000026412
RefSeq Acc Id: XP_038327044   ⟸   XM_038471116
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038452222   ⟸   XM_038596294
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038516296   ⟸   XM_038660368
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038387959   ⟸   XM_038532031
- Peptide Label: isoform X4
RefSeq Acc Id: ENSCAFP00845003618   ⟸   ENSCAFT00845004530
RefSeq Acc Id: ENSCAFP00845003647   ⟸   ENSCAFT00845004565
Protein Domains
FAT   FATC   PI3K/PI4K


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000016648 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030018596 UniProtKB/TrEMBL
  ENSCAFG00040006675 UniProtKB/TrEMBL
  ENSCAFG00845002541 Ensembl, ENTREZGENE
Ensembl Protein ENSCAFP00000024527 UniProtKB/TrEMBL
  ENSCAFP00000044316 UniProtKB/TrEMBL
  ENSCAFP00000047415 UniProtKB/TrEMBL
  ENSCAFP00000048878 UniProtKB/TrEMBL
  ENSCAFP00000054233 UniProtKB/TrEMBL
  ENSCAFP00000063184 UniProtKB/TrEMBL
  ENSCAFP00000065177 UniProtKB/TrEMBL
  ENSCAFP00030029869 UniProtKB/TrEMBL
  ENSCAFP00030030180 UniProtKB/TrEMBL
  ENSCAFP00040010776 UniProtKB/TrEMBL
  ENSCAFP00845003647 ENTREZGENE
Ensembl Transcript ENSCAFT00000026412 UniProtKB/TrEMBL
  ENSCAFT00000064130 UniProtKB/TrEMBL
  ENSCAFT00000070228 UniProtKB/TrEMBL
  ENSCAFT00000074234 UniProtKB/TrEMBL
  ENSCAFT00000077589 UniProtKB/TrEMBL
  ENSCAFT00000082268 UniProtKB/TrEMBL
  ENSCAFT00000084601 UniProtKB/TrEMBL
  ENSCAFT00030034256 UniProtKB/TrEMBL
  ENSCAFT00030034603 UniProtKB/TrEMBL
  ENSCAFT00040012432 UniProtKB/TrEMBL
  ENSCAFT00845004565 ENTREZGENE
Gene3D-CATH 1.10.1070.11 UniProtKB/TrEMBL
  1.20.120.150 UniProtKB/TrEMBL
  1.25.10.10 UniProtKB/TrEMBL
  1.25.40.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  DUF3385_TOR UniProtKB/TrEMBL
  FATC_dom UniProtKB/TrEMBL
  FRB_dom UniProtKB/TrEMBL
  FRB_sf UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  PI3/4_kinase_cat_dom UniProtKB/TrEMBL
  PI3/4_kinase_cat_sf UniProtKB/TrEMBL
  PI3/4_kinase_CS UniProtKB/TrEMBL
  PIK-rel_kinase_FAT UniProtKB/TrEMBL
  PIK_FAT UniProtKB/TrEMBL
  TOR UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
NCBI Gene MTOR ENTREZGENE
PANTHER PTHR11139:SF9 UniProtKB/TrEMBL
Pfam DUF3385 UniProtKB/TrEMBL
  FAT UniProtKB/TrEMBL
  FATC UniProtKB/TrEMBL
  FRB_dom UniProtKB/TrEMBL
  PI3_PI4_kinase UniProtKB/TrEMBL
PROSITE FAT UniProtKB/TrEMBL
  FATC UniProtKB/TrEMBL
  PI3_4_KINASE_1 UniProtKB/TrEMBL
  PI3_4_KINASE_2 UniProtKB/TrEMBL
  PI3_4_KINASE_3 UniProtKB/TrEMBL
SMART DUF3385 UniProtKB/TrEMBL
  FATC UniProtKB/TrEMBL
  PI3Kc UniProtKB/TrEMBL
Superfamily-SCOP SSF47212 UniProtKB/TrEMBL
  SSF48371 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A5F4BRA0_CANLF UniProtKB/TrEMBL
  A0A5F4C325_CANLF UniProtKB/TrEMBL
  A0A5F4C3W4_CANLF UniProtKB/TrEMBL
  A0A5F4CJ07_CANLF UniProtKB/TrEMBL
  A0A5F4D8S1_CANLF UniProtKB/TrEMBL
  A0A5F4DER1_CANLF UniProtKB/TrEMBL
  A0A8C0NQB2_CANLF UniProtKB/TrEMBL
  A0A8C0Q917_CANLF UniProtKB/TrEMBL
  E2R2L2 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:43490 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-08-08 MTOR  mechanistic target of rapamycin kinase    mechanistic target of rapamycin  Symbol and/or name change 5135510 APPROVED