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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:forkhead class A signaling pathway
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Accession:PW:0000958 term browser browse the term
Definition:The signaling pathway mediated by the FoxA subgroup of forkhead family of transcription factors plays important roles in development and in modulating steroid hormone signaling. Three FoxA genes carry out overlapping yet distinct functions. FOXA1 appears to modulate steroid receptor activity in breast and prostate cancer.
Synonyms:related_synonym: FoxA signaling pathway;   PID:200087;   PID:200226


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forkhead class A signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 ISO PID PID:200087 NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain ISO PID PID:200087 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147 		JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain ISO PID PID:200087 NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075 		JBrowse link
G Afp alpha-fetoprotein ISO PID PID:200087 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO PID PID:200087 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 ISO PID PID:200087 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Alb albumin ISO PID PID:200087 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B ISO PID PID:200087 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116 		JBrowse link
G Ap1b1 adaptor related protein complex 1 subunit beta 1 ISO PID PID:200226 NCBI chr14:79,879,482...79,930,778
Ensembl chr14:79,879,533...79,930,778 		JBrowse link
G Apoa1 apolipoprotein A1 ISO PID PID:200087 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apob apolipoprotein B ISO PID PID:200226 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Ar androgen receptor ISO PID PID:200226 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 ISO PID PID:200226 NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119 		JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 ISO PID PID:200087 NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671 		JBrowse link
G Brca1 BRCA1, DNA repair associated ISO PID PID:200226 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G C4bpb complement component 4 binding protein, beta ISO PID PID:200226 NCBI chr13:42,120,798...42,131,515
Ensembl chr13:42,120,798...42,131,817 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B ISO PID PID:200226 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha ISO PID PID:200087 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta ISO PID PID:200087 PID:200226 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta ISO PID PID:200087 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829 		JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain ISO PID PID:200226 NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A ISO PID PID:200087 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B ISO PID PID:200087 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404 		JBrowse link
G Cpt1c carnitine palmitoyltransferase 1c ISO PID PID:200087 NCBI chr 1:95,442,814...95,457,347
Ensembl chr 1:95,442,817...95,457,342 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 ISO PID PID:200087 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crebbp CREB binding protein ISO PID PID:200226 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 ISO PID PID:200226 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 ISO PID PID:200087 NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522 		JBrowse link
G Dscam DS cell adhesion molecule ISO PID PID:200226 NCBI chr11:35,921,924...36,507,100
Ensembl chr11:35,926,896...36,507,415 		JBrowse link
G Ep300 E1A binding protein p300 ISO PID PID:200226 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Esr1 estrogen receptor 1 ISO PID PID:200226 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G F2 coagulation factor II, thrombin ISO PID PID:200087 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO PID PID:200226 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Foxa1 forkhead box A1 ISO PID PID:200087 PID:200226 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Foxa2 forkhead box A2 ISO PID PID:200087 PID:200226 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Foxa3 forkhead box A3 ISO PID PID:200087 PID:200226 NCBI chr 1:78,662,067...78,672,321
Ensembl chr 1:78,662,431...78,672,155 		JBrowse link
G Foxf1 forkhead box F1 ISO PID PID:200087 NCBI chr19:49,153,949...49,157,741
Ensembl chr19:49,153,699...49,157,738 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 ISO PID PID:200087 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G Gcg glucagon ISO PID PID:200226 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Gck glucokinase ISO PID PID:200087 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase ISO PID PID:200087 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 ISO PID PID:200087 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hnf1a HNF1 homeobox A ISO PID PID:200087 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
G Hnf1b HNF1 homeobox B ISO PID PID:200087 NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha ISO PID PID:200087 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 ISO PID PID:200087 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Ins2 insulin 2 ISO PID PID:200087 PID:200226 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO PID PID:200226 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 ISO PID PID:200087 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082 		JBrowse link
G Klk1c10 kallikrein 1-related peptidase C10 ISO PID PID:200226 NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052 		JBrowse link
G Ncoa3 nuclear receptor coactivator 3 ISO PID PID:200226 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594 		JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 ISO PID PID:200226 NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074
Ensembl chr13:9,612,431...9,623,074 		JBrowse link
G Nf1 neurofibromin 1 ISO PID PID:200087 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Nfia nuclear factor I/A ISO PID PID:200226 NCBI chr 5:112,436,655...112,781,878
Ensembl chr 5:112,436,644...112,775,885 		JBrowse link
G Nfib nuclear factor I/B ISO PID PID:200226 NCBI chr 5:96,759,208...96,974,001
Ensembl chr 5:96,764,653...96,975,479 		JBrowse link
G Nfic nuclear factor I/C ISO PID PID:200226 NCBI chr 7:8,278,210...8,309,936
Ensembl chr 7:8,253,361...8,309,936 		JBrowse link
G Nkx2-1 NK2 homeobox 1 ISO PID PID:200087 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
G Nkx3-1 NK3 homeobox 1 ISO PID PID:200226 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 ISO PID PID:200226 NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 ISO PID PID:200087 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nrip1 nuclear receptor interacting protein 1 ISO PID PID:200226 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 ISO PID PID:200087 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 ISO PID PID:200087 NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064 		JBrowse link
G Pisd phosphatidylserine decarboxylase ISO PID PID:200226 NCBI chr14:77,941,927...77,991,021
Ensembl chr14:77,941,948...77,991,003 		JBrowse link
G Pklr pyruvate kinase L/R ISO PID PID:200087 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870 		JBrowse link
G Pou2f1 POU class 2 homeobox 1 ISO PID PID:200226 NCBI chr13:78,120,617...78,263,306
Ensembl chr13:78,130,685...78,263,363 		JBrowse link
G Prdm15 PR/SET domain 15 ISO PID PID:200226 NCBI chr11:37,164,608...37,225,172
Ensembl chr11:37,165,575...37,222,207 		JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 ISO PID PID:200226 NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610 		JBrowse link
G Serpina1 serpin family A member 1 ISO PID PID:200226 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339 		JBrowse link
G Sftpa1 surfactant protein A1 ISO PID PID:200226 NCBI chr16:17,008,180...17,011,686
Ensembl chr16:17,008,180...17,011,685 		JBrowse link
G Sftpd surfactant protein D ISO PID PID:200226 NCBI chr16:17,046,491...17,058,968
Ensembl chr16:17,046,483...17,059,927 		JBrowse link
G Shh sonic hedgehog signaling molecule ISO PID PID:200226 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 ISO PID PID:200087 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933 		JBrowse link
G Sod1 superoxide dismutase 1 ISO PID PID:200226 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sp1 Sp1 transcription factor ISO PID PID:200087 PID:200226 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961 		JBrowse link
G Tat tyrosine aminotransferase ISO PID PID:200087 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
G Tff1 trefoil factor 1 ISO PID PID:200226 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597 		JBrowse link
G Tfrc transferrin receptor ISO PID PID:200087 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Ttr transthyretin ISO PID PID:200087 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G Ucp2 uncoupling protein 2 ISO PID PID:200087 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
G Vtn vitronectin ISO PID PID:200226 NCBI chr10:63,394,732...63,397,812
Ensembl chr10:63,394,719...63,397,810 		JBrowse link
G Xbp1 X-box binding protein 1 ISO PID PID:200226 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6092
    signaling pathway 2635
      transcription factor mediated signaling pathway 445
        forkhead signaling pathway 82
          forkhead class A signaling pathway 82
Path 2
Term Annotations click to browse term
  pathway 6092
    regulatory pathway 3867
      pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis 1738
        transcription pathway 1059
          transcription pathway via transcription factor mediated signaling 445
            forkhead signaling pathway 82
              forkhead class A signaling pathway 82
paths to the root