altered pathway pertinent to DNA replication and repair, cell cycle, maintenance of genomic integrity, RNA and protein biosynthesis +
cell cycle pathway +
chromatin modification/remodeling pathway +
DNA biosynthetic pathway
DNA damage response pathway +
DNA repair pathway +
DNA replication pathway +
mTOR signaling pathway +
non-coding RNA pathway +
RNA processing pathway +
RNA transport pathway +
transcription pathway +
The pathways governing and/or regulating DNA transcription and gene expression. DNA transcription into coding and non-coding RNA is accomplished by one prokaryotic and several eukaryotic RNA polymerases. Transcription-coupled repair handles DNA lesions that interfere with the progression of RNA polymerases. Splicing of nascent RNA is thought to be predominantly co-transcriptional. Signaling pathways mediated by various transcription factors are involved in the regulation of gene expression.