RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: pyelonephritis
Accession: DOID:11400
browse the term
Definition: Inflammation of the KIDNEY involving the renal parenchyma (the NEPHRONS); KIDNEY PELVIS; and KIDNEY CALICES. It is characterized by ABDOMINAL PAIN; FEVER; NAUSEA; VOMITING; and occasionally DIARRHEA.
Synonyms: exact_synonym: Necrotizing Pyelonephritis; Pyelonephritides; Pyelonephritis, Acute Necrotizing
primary_id: MESH:D011704
xref: EFO:1001141 ; ICD10CM:N16 ; ICD9CM:590.80 ; NCI:C34965
For additional species annotation, visit the
Alliance of Genome Resources .
Please select species to view GViewer data.
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
N
Ace
angiotensin I converting enzyme
ISO
protein:decreased expression:kidney, brush border epithelial cell (human)
RGD
PMID:10504496
RGD:8158033
NCBI chrNW_004624849:998,262...1,019,305
Ensembl chrNW_004624849:998,277...1,019,521
G
P
ACE
angiotensin I converting enzyme
ISO
protein:decreased expression:kidney, brush border epithelial cell (human)
RGD
PMID:10504496
RGD:8158033
NCBI chr12:15,394,487...15,414,609
Ensembl chr12:15,394,487...15,414,703
G
D
ACE
angiotensin I converting enzyme
ISO
protein:decreased expression:kidney, brush border epithelial cell (human)
RGD
PMID:10504496
RGD:8158033
NCBI chr 9:11,497,182...11,516,362
Ensembl chr 9:11,497,182...11,516,358
G
B
ACE
angiotensin I converting enzyme
ISO
protein:decreased expression:kidney, brush border epithelial cell (human)
RGD
PMID:10504496
RGD:8158033
NCBI chr17:57,556,294...57,577,294
Ensembl chr17:62,702,341...62,733,853
G
R
Ace
angiotensin I converting enzyme
ISO
protein:decreased expression:kidney, brush border epithelial cell (human)
RGD
PMID:10504496
RGD:8158033
NCBI chr10:91,410,129...91,430,246
Ensembl chr10:90,910,316...90,931,131
G
M
Ace
angiotensin I converting enzyme
ISO
protein:decreased expression:kidney, brush border epithelial cell (human)
RGD
PMID:10504496
RGD:8158033
NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
G
H
ACE
angiotensin I converting enzyme
IEP
protein:decreased expression:kidney, brush border epithelial cell (human)
RGD
PMID:10504496
RGD:8158033
NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
G
N
Ambp
alpha-1-microglobulin/bikunin precursor
ISO
RGD
PMID:19205372
RGD:6904156
NCBI chrNW_004624760:21,047,576...21,064,698
Ensembl chrNW_004624760:21,047,303...21,068,076
G
G
AMBP
alpha-1-microglobulin/bikunin precursor
ISO
RGD
PMID:19205372
RGD:6904156
NCBI chr12:25,508,516...25,526,821
Ensembl chr12:25,508,682...25,527,016
G
P
AMBP
alpha-1-microglobulin/bikunin precursor
ISO
RGD
PMID:19205372
RGD:6904156
NCBI chr 1:254,683,885...254,703,220
Ensembl chr 1:254,683,891...254,703,225
G
S
Ambp
alpha-1-microglobulin/bikunin precursor
ISO
RGD
PMID:19205372
RGD:6904156
NCBI chrNW_004936487:3,399,792...3,412,088
G
D
AMBP
alpha-1-microglobulin/bikunin precursor
ISO
RGD
PMID:19205372
RGD:6904156
NCBI chr11:68,338,644...68,353,366
Ensembl chr11:68,338,389...68,351,994
G
B
AMBP
alpha-1-microglobulin/bikunin precursor
ISO
RGD
PMID:19205372
RGD:6904156
NCBI chr 9:85,157,680...85,176,253
Ensembl chr 9:113,525,835...113,543,422
G
C
Ambp
alpha-1-microglobulin/bikunin precursor
ISO
RGD
PMID:19205372
RGD:6904156
NCBI chrNW_004955419:13,478,904...13,492,329
Ensembl chrNW_004955419:13,478,552...13,492,327
G
R
Ambp
alpha-1-microglobulin/bikunin precursor
ISO
RGD
PMID:19205372
RGD:6904156
NCBI chr 5:81,583,621...81,593,938
Ensembl chr 5:76,568,094...76,578,331
G
M
Ambp
alpha 1 microglobulin/bikunin precursor
ISO
RGD
PMID:19205372
RGD:6904156
NCBI chr 4:63,061,512...63,072,409
Ensembl chr 4:63,061,512...63,073,036
G
H
AMBP
alpha-1-microglobulin/bikunin precursor
IEP
RGD
PMID:19205372
RGD:6904156
NCBI chr 9:114,060,127...114,078,300
Ensembl chr 9:114,060,127...114,078,328
G
N
B2m
beta-2-microglobulin
ISO
protein:increased expression:urine
RGD
PMID:21797109
RGD:6482315
NCBI chrNW_004624804:11,514,728...11,521,625
G
G
B2M
beta-2-microglobulin
ISO
protein:increased expression:urine
RGD
PMID:21797109
RGD:6482315
NCBI chr26:38,331,818...38,338,785
Ensembl chr26:38,331,442...38,338,809
G
P
B2M
beta-2-microglobulin
ISO
protein:increased expression:urine
RGD
PMID:21797109
RGD:6482315
NCBI chr 1:126,837,721...126,844,043
Ensembl chr 1:126,835,143...126,981,582
G
S
B2m
beta-2-microglobulin
ISO
protein:increased expression:urine
RGD
PMID:21797109
RGD:6482315
NCBI chrNW_004936471:7,646,504...7,655,656
Ensembl chrNW_004936471:7,646,373...7,655,778
G
D
B2M
beta-2-microglobulin
ISO
protein:increased expression:urine
RGD
PMID:21797109
RGD:6482315
NCBI chr30:11,331,574...11,337,991
Ensembl chr30:11,331,569...11,337,997
G
B
B2M
beta-2-microglobulin
ISO
protein:increased expression:urine
RGD
PMID:21797109
RGD:6482315
NCBI chr15:23,668,108...23,674,791
Ensembl chr15:41,836,345...41,842,991
G
C
B2m
beta-2-microglobulin
ISO
protein:increased expression:urine
RGD
PMID:21797109
RGD:6482315
NCBI chrNW_004955416:11,205,503...11,211,325
Ensembl chrNW_004955416:11,204,849...11,215,568
G
R
B2m
beta-2 microglobulin
IEP
protein:increased expression:urine
RGD
PMID:21797109
RGD:6482315
NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:109,095,729...109,101,766
G
M
B2m
beta-2 microglobulin
ISO
RGD
PMID:21797109
RGD:6482315
NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564
G
H
B2M
beta-2-microglobulin
ISO
RGD
PMID:21797109
RGD:6482315
NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851
G
N
Bmp7
bone morphogenetic protein 7
ISO
protein:decreased expression:kidney
RGD
PMID:16034630
RGD:2289039
NCBI chrNW_004624741:23,658,214...23,743,227
Ensembl chrNW_004624741:23,658,004...23,737,742
G
G
BMP7
bone morphogenetic protein 7
ISO
protein:decreased expression:kidney
RGD
PMID:16034630
RGD:2289039
NCBI chr 2:6,856,396...6,954,948
Ensembl chr 2:6,856,453...6,954,944
G
P
BMP7
bone morphogenetic protein 7
ISO
protein:decreased expression:kidney
RGD
PMID:16034630
RGD:2289039
NCBI chr17:57,567,770...57,676,516
Ensembl chr17:57,584,956...57,675,986
G
S
Bmp7
bone morphogenetic protein 7
ISO
protein:decreased expression:kidney
RGD
PMID:16034630
RGD:2289039
NCBI chrNW_004936530:71,965...143,940
Ensembl chrNW_004936530:71,920...143,940
G
D
BMP7
bone morphogenetic protein 7
ISO
protein:decreased expression:kidney
RGD
PMID:16034630
RGD:2289039
NCBI chr24:42,203,183...42,294,105
Ensembl chr24:42,204,823...42,294,653
G
B
BMP7
bone morphogenetic protein 7
ISO
protein:decreased expression:kidney
RGD
PMID:16034630
RGD:2289039
NCBI chr20:53,509,484...53,606,889
Ensembl chr20:54,788,974...54,885,021
G
C
Bmp7
bone morphogenetic protein 7
ISO
protein:decreased expression:kidney
RGD
PMID:16034630
RGD:2289039
NCBI chrNW_004955445:2,154,057...2,235,594
Ensembl chrNW_004955445:2,153,170...2,235,795
G
R
Bmp7
bone morphogenetic protein 7
IEP
protein:decreased expression:kidney
RGD
PMID:16034630
RGD:2289039
NCBI chr 3:182,059,318...182,135,273
Ensembl chr 3:161,516,462...161,716,788
G
M
Bmp7
bone morphogenetic protein 7
ISO
protein:decreased expression:kidney
RGD
PMID:16034630
RGD:2289039
NCBI chr 2:172,709,805...172,782,114
Ensembl chr 2:172,709,805...172,782,114
G
H
BMP7
bone morphogenetic protein 7
ISO
protein:decreased expression:kidney
RGD
PMID:16034630
RGD:2289039
NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641
G
N
Calca
calcitonin related polypeptide alpha
ISO
RGD
PMID:15286264
RGD:7205498
NCBI chrNW_004624766:6,764,388...6,771,396
Ensembl chrNW_004624766:6,766,185...6,768,173
G
S
Calca
calcitonin related polypeptide alpha
ISO
RGD
PMID:15286264
RGD:7205498
NCBI chrNW_004936528:3,800,801...3,806,000
Ensembl chrNW_004936528:3,800,577...3,805,004
G
B
CALCA
calcitonin related polypeptide alpha
ISO
RGD
PMID:15286264
RGD:7205498
NCBI chr11:15,055,897...15,061,539
Ensembl chr11:14,745,588...14,751,267
G
R
Calca
calcitonin-related polypeptide alpha
ISO
RGD
PMID:15286264
RGD:7205498
NCBI chr 1:178,312,636...178,317,588
Ensembl chr 1:168,878,214...168,883,105
G
M
Calca
calcitonin/calcitonin-related polypeptide, alpha
ISO
RGD
PMID:15286264
RGD:7205498
NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
G
H
CALCA
calcitonin related polypeptide alpha
IEP
RGD
PMID:15286264
RGD:7205498
NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354
G
P
CALCB
calcitonin-related polypeptide beta
ISO
RGD
PMID:15286264
RGD:7205498
NCBI chr 2:44,043,135...44,048,651
G
N
Cfb
complement factor B
ISO
associated with pregnancy complications;protein:increased activity:plasma
RGD
PMID:20218820
RGD:7242756
NCBI chrNW_004624754:24,310,344...24,316,482
Ensembl chrNW_004624754:24,310,247...24,317,366
G
G
CFB
complement factor B
ISO
associated with pregnancy complications;protein:increased activity:plasma
RGD
PMID:20218820
RGD:7242756
Ensembl chr17:40,069,909...40,094,207
G
P
CFB
complement factor B
ISO
associated with pregnancy complications;protein:increased activity:plasma
RGD
PMID:20218820
RGD:7242756
NCBI chr 7:24,034,077...24,040,523
Ensembl chr 7:24,034,332...24,041,179
G
S
Cfb
complement factor B
ISO
associated with pregnancy complications;protein:increased activity:plasma
RGD
PMID:20218820
RGD:7242756
NCBI chrNW_004936727:1,595,872...1,602,274
Ensembl chrNW_004936727:1,595,499...1,602,215
G
D
CFB
complement factor B
ISO
associated with pregnancy complications;protein:increased activity:plasma
RGD
PMID:20218820
RGD:7242756
NCBI chr12:1,400,143...1,406,267
G
B
CFB
complement factor B
ISO
associated with pregnancy complications;protein:increased activity:plasma
RGD
PMID:20218820
RGD:7242756
NCBI chr 6:31,606,716...31,612,782
G
C
Cfb
complement factor B
ISO
associated with pregnancy complications;protein:increased activity:plasma
RGD
PMID:20218820
RGD:7242756
NCBI chrNW_004955437:461,235...466,908
Ensembl chrNW_004955437:461,235...470,464
G
R
Cfb
complement factor B
ISO
associated with pregnancy complications;protein:increased activity:plasma
RGD
PMID:20218820
RGD:7242756
NCBI chr20:3,975,271...3,981,138
Ensembl chr20:3,951,474...3,976,505
G
M
Cfb
complement factor B
ISO
associated with pregnancy complications;protein:increased activity:plasma
RGD
PMID:20218820
RGD:7242756
NCBI chr17:35,075,350...35,081,492
Ensembl chr17:35,075,350...35,081,494
G
H
CFB
complement factor B
IEP
associated with pregnancy complications;protein:increased activity:plasma
RGD
PMID:20218820
RGD:7242756
NCBI chr 6:31,946,095...31,952,084
Ensembl chr 6:31,945,650...31,952,086
G
N
Crp
C-reactive protein
ISO
RGD
PMID:21797109
RGD:6482315
NCBI chrNW_004624794:1,531,555...1,533,804
Ensembl chrNW_004624794:1,531,571...1,533,804
G
G
CRP
C-reactive protein
ISO
RGD
PMID:21797109
RGD:6482315
NCBI chr20:4,232,262...4,235,826
Ensembl chr20:4,232,913...4,235,377
G
P
CRP
C-reactive protein, pentraxin-related
ISO
RGD
PMID:21797109
RGD:6482315
NCBI chr 4:90,793,361...90,801,020
Ensembl chr 4:90,793,350...90,805,218
G
S
Crp
C-reactive protein
ISO
RGD
PMID:21797109
RGD:6482315
NCBI chrNW_004936740:885,855...888,854
Ensembl chrNW_004936740:883,272...890,606
G
D
CRP
C-reactive protein
ISO
RGD
PMID:21797109
RGD:6482315
NCBI chr38:22,396,787...22,398,180
Ensembl chr38:22,396,263...22,399,166
G
B
CRP
C-reactive protein
ISO
RGD
PMID:21797109
RGD:6482315
NCBI chr 1:135,062,102...135,064,402
G
R
Crp
C-reactive protein
IEP
RGD
PMID:21797109
RGD:6482315
NCBI chr13:87,694,062...87,695,978
Ensembl chr13:85,124,977...85,175,178
G
M
Crp
C-reactive protein, pentraxin-related
ISO
RGD
PMID:21797109
RGD:6482315
NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
G
H
CRP
C-reactive protein
ISO
RGD
PMID:21797109
RGD:6482315
NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589
G
D
CRSP-3
calcitonin receptor-stimulating peptide 3
ISO
RGD
PMID:15286264
RGD:7205498
NCBI chr21:37,676,841...37,680,643
Ensembl chr21:37,676,841...37,680,645
G
N
Cxcr1
C-X-C motif chemokine receptor 1
ISO
DNA:SNP: :2608G>C (human) DNA:mutations, polymorphisms: :multiple
RGD
PMID:17786197 PMID:22325052
RGD:7207860 RGD:7207864
NCBI chrNW_004624823:6,857,649...6,861,219
Ensembl chrNW_004624823:6,859,356...6,860,426
G
G
CXCR1
C-X-C motif chemokine receptor 1
ISO
DNA:mutations, polymorphisms: :multiple DNA:SNP: :2608G>C (human)
RGD
PMID:17786197 PMID:22325052
RGD:7207860 RGD:7207864
NCBI chr10:104,052,709...104,056,388
Ensembl chr10:104,053,544...104,054,620
G
S
Cxcr1
C-X-C motif chemokine receptor 1
ISO
DNA:SNP: :2608G>C (human) DNA:mutations, polymorphisms: :multiple
RGD
PMID:17786197 PMID:22325052
RGD:7207860 RGD:7207864
NCBI chrNW_004936569:715,129...716,187
Ensembl chrNW_004936569:715,129...716,181
G
B
CXCR1
C-X-C motif chemokine receptor 1
ISO
DNA:mutations, polymorphisms: :multiple DNA:SNP: :2608G>C (human)
RGD
PMID:17786197 PMID:22325052
RGD:7207860 RGD:7207864
NCBI chr2B:105,429,576...105,433,243
Ensembl chr2B:224,028,838...224,029,890
G
C
Cxcr1
C-X-C motif chemokine receptor 1
ISO
DNA:SNP: :2608G>C (human) DNA:mutations, polymorphisms: :multiple
RGD
PMID:17786197 PMID:22325052
RGD:7207860 RGD:7207864
NCBI chrNW_004955453:15,181,027...15,196,224
Ensembl chrNW_004955453:15,194,205...15,195,272
G
R
Cxcr1
C-X-C motif chemokine receptor 1
ISO
DNA:SNP: :2608G>C (human) DNA:mutations, polymorphisms: :multiple
RGD
PMID:22325052 PMID:17786197
RGD:7207860 , RGD:7207864
NCBI chr 9:83,216,040...83,220,225
Ensembl chr 9:75,766,770...75,771,084
G
M
Cxcr1
C-X-C motif chemokine receptor 1
ISO
DNA:SNP: :2608G>C (human) DNA:mutations, polymorphisms: :multiple
RGD
PMID:22325052 PMID:17786197
RGD:7207860 , RGD:7207864
NCBI chr 1:74,228,862...74,233,867
Ensembl chr 1:74,230,944...74,233,790
G
H
CXCR1
C-X-C motif chemokine receptor 1
IAGP
DNA:SNP: :2608G>C (human) DNA:mutations, polymorphisms: :multiple
RGD
PMID:22325052 PMID:17786197
RGD:7207860 , RGD:7207864
NCBI chr 2:218,162,841...218,166,962
Ensembl chr 2:218,162,841...218,166,962
G
P
CXCR2
C-X-C motif chemokine receptor 2
ISO
RGD
PMID:21814172
RGD:7257675
NCBI chr15:120,219,657...120,230,203
G
D
CXCR2
C-X-C motif chemokine receptor 2
ISO
RGD
PMID:21814172
RGD:7257675
NCBI chr37:24,831,351...24,846,387
Ensembl chr37:24,843,171...24,844,247
G
B
CXCR2
C-X-C motif chemokine receptor 2
ISO
RGD
PMID:21814172
RGD:7257675
NCBI chr2B:105,387,198...105,400,533
Ensembl chr2B:223,997,066...223,998,148
G
R
Cxcr2
C-X-C motif chemokine receptor 2
ISO
RGD
PMID:21814172
RGD:7257675
NCBI chr 9:83,178,645...83,185,017
Ensembl chr 9:75,729,115...75,739,425
G
M
Cxcr2
C-X-C motif chemokine receptor 2
IMP
RGD
PMID:21814172
RGD:7257675
NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405
G
H
CXCR2
C-X-C motif chemokine receptor 2
ISO
RGD
PMID:21814172
RGD:7257675
NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251
G
G
CYB5A
cytochrome b5 type A
ISO
RGD
PMID:9848217
RGD:1599663
NCBI chr18:5,599,198...5,636,620
Ensembl chr18:5,599,206...5,640,012
G
P
CYB5A
cytochrome b5 type A
ISO
RGD
PMID:9848217
RGD:1599663
NCBI chr 1:149,737,584...149,773,222
Ensembl chr 1:149,737,571...149,773,219
G
R
Cyb5a
cytochrome b5 type A
IEP
RGD
PMID:9848217
RGD:1599663
NCBI chr18:80,487,923...80,520,544
Ensembl chr18:78,202,342...78,258,535 Ensembl chr18:78,202,342...78,258,535
G
M
Cyb5a
cytochrome b5 type A (microsomal)
ISO
RGD
PMID:9848217
RGD:1599663
NCBI chr18:84,869,463...84,897,996
Ensembl chr18:84,856,829...84,897,996
G
H
CYB5A
cytochrome b5 type A
ISO
RGD
PMID:9848217
RGD:1599663
NCBI chr18:74,250,846...74,291,963
Ensembl chr18:74,250,846...74,291,973
G
N
Il1rn
interleukin 1 receptor antagonist
ISO
protein:increased expression:urine (human)
RGD
PMID:8640042
RGD:6907372
NCBI chrNW_004624749:13,210,365...13,224,471
Ensembl chrNW_004624749:13,210,476...13,225,890
G
G
IL1RN
interleukin 1 receptor antagonist
ISO
protein:increased expression:urine (human)
RGD
PMID:8640042
RGD:6907372
NCBI chr14:16,136,667...16,152,451
Ensembl chr14:16,146,333...16,151,326
G
P
IL1RN
interleukin 1 receptor antagonist
ISO
protein:increased expression:urine (human)
RGD
PMID:8640042
RGD:6907372
G
S
Il1rn
interleukin 1 receptor antagonist
ISO
protein:increased expression:urine (human)
RGD
PMID:8640042
RGD:6907372
NCBI chrNW_004936783:1,447,158...1,466,331
Ensembl chrNW_004936783:1,447,106...1,466,340
G
D
IL1RN
interleukin 1 receptor antagonist
ISO
protein:increased expression:urine (human)
RGD
PMID:8640042
RGD:6907372
NCBI chr17:37,236,690...37,250,424
Ensembl chr17:37,212,751...37,249,329
G
B
IL1RN
interleukin 1 receptor antagonist
ISO
protein:increased expression:urine (human)
RGD
PMID:8640042
RGD:6907372
NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839
G
C
Il1rn
interleukin 1 receptor antagonist
ISO
protein:increased expression:urine (human)
RGD
PMID:8640042
RGD:6907372
NCBI chrNW_004955470:1,145,022...1,159,413
Ensembl chrNW_004955470:1,144,810...1,159,471
G
R
Il1rn
interleukin 1 receptor antagonist
ISO
protein:increased expression:urine (human)
RGD
PMID:8640042
RGD:6907372
NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:7,111,550...7,127,445
G
M
Il1rn
interleukin 1 receptor antagonist
ISO
protein:increased expression:urine (human)
RGD
PMID:8640042
RGD:6907372
NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
G
H
IL1RN
interleukin 1 receptor antagonist
IEP
protein:increased expression:urine (human)
RGD
PMID:8640042
RGD:6907372
NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016
G
G
IL3
interleukin 3
ISO
mRNA:increased expression:kidney
RGD
PMID:18214547
RGD:2317665
NCBI chr23:34,894,630...34,899,105
G
S
Il3
interleukin 3
ISO
mRNA:increased expression:kidney
RGD
PMID:18214547
RGD:2317665
NCBI chrNW_004936647:3,102,922...3,104,758
G
D
IL3
interleukin 3
ISO
mRNA:increased expression:kidney
RGD
PMID:18214547
RGD:2317665
NCBI chr11:20,330,480...20,332,668
Ensembl chr11:20,330,480...20,332,668
G
B
IL3
interleukin 3
ISO
mRNA:increased expression:kidney
RGD
PMID:18214547
RGD:2317665
NCBI chr 5:127,483,843...127,486,388
Ensembl chr 5:133,647,667...133,650,213
G
R
Il3
interleukin 3
IEP
mRNA:increased expression:kidney
RGD
PMID:18214547
RGD:2317665
NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,405,716...38,408,066
G
M
Il3
interleukin 3
ISO
mRNA:increased expression:kidney
RGD
PMID:18214547
RGD:2317665
NCBI chr11:54,155,911...54,158,105
Ensembl chr11:54,156,129...54,158,103
G
H
IL3
interleukin 3
ISO
mRNA:increased expression:kidney
RGD
PMID:18214547
RGD:2317665
NCBI chr 5:132,060,655...132,063,204
Ensembl chr 5:132,060,655...132,063,204
G
B
LOC100968898
cytochrome b5
ISO
RGD
PMID:9848217
RGD:1599663
NCBI chr18:67,638,406...67,677,111
Ensembl chr18:70,919,617...70,957,732
G
N
LOC101711375
cytochrome b5
ISO
RGD
PMID:9848217
RGD:1599663
NCBI chrNW_004624806:6,399,708...6,434,667
Ensembl chrNW_004624806:6,399,460...6,436,735
G
S
LOC101960314
cytochrome b5
ISO
RGD
PMID:9848217
RGD:1599663
NCBI chrNW_004936616:4,176,576...4,210,276
G
S
LOC101968921
angiotensin-converting enzyme
ISO
protein:decreased expression:kidney, brush border epithelial cell (human)
RGD
PMID:10504496
RGD:8158033
NCBI chrNW_004936541:4,157,847...4,178,156
Ensembl chrNW_004936541:4,157,393...4,178,177
G
C
LOC102012144
cytochrome b5
ISO
RGD
PMID:9848217
RGD:1599663
NCBI chrNW_004955402:57,701,931...57,739,163
Ensembl chrNW_004955402:57,701,931...57,739,163
G
G
LOC103217855
C-X-C chemokine receptor type 2
ISO
RGD
PMID:21814172
RGD:7257675
NCBI chr10:104,012,906...104,025,599
Ensembl chr10:104,022,811...104,023,893
G
G
LOC103239768
calcitonin
ISO
RGD
PMID:15286264
RGD:7205498
NCBI chr 1:49,946,574...49,956,010
Ensembl chr 1:49,951,694...49,954,092
G
D
LOC476167
cytochrome b5 type A pseudogene
ISO
RGD
PMID:9848217
RGD:1599663
NCBI chr 1:5,070,817...5,106,668
Ensembl chr 1:5,070,865...5,106,932
G
N
Pgf
placental growth factor
ISO
protein:decreased expression:plasma
RGD
PMID:20213923
RGD:6483586
NCBI chrNW_004624734:26,751,986...26,764,154
Ensembl chrNW_004624734:26,751,530...26,764,242
G
G
PGF
placental growth factor
ISO
protein:decreased expression:plasma
RGD
PMID:20213923
RGD:6483586
NCBI chr24:52,160,904...52,174,493
Ensembl chr24:52,161,787...52,173,989
G
P
PGF
placental growth factor
ISO
protein:decreased expression:plasma
RGD
PMID:20213923
RGD:6483586
NCBI chr 7:98,149,510...98,162,784
Ensembl chr 7:98,148,994...98,162,741
G
S
Pgf
placental growth factor
ISO
protein:decreased expression:plasma
RGD
PMID:20213923
RGD:6483586
NCBI chrNW_004936488:4,098,187...4,111,108
Ensembl chrNW_004936488:4,098,225...4,111,142
G
D
PGF
placental growth factor
ISO
protein:decreased expression:plasma
RGD
PMID:20213923
RGD:6483586
NCBI chr 8:48,059,554...48,110,534
Ensembl chr 8:48,059,552...48,075,170
G
B
PGF
placental growth factor
ISO
protein:decreased expression:plasma
RGD
PMID:20213923
RGD:6483586
NCBI chr14:55,494,152...55,508,066
Ensembl chr14:74,338,976...74,352,964
G
C
Pgf
placental growth factor
ISO
protein:decreased expression:plasma
RGD
PMID:20213923
RGD:6483586
NCBI chrNW_004955523:616,196...627,055
Ensembl chrNW_004955523:616,154...627,713
G
R
Pgf
placental growth factor
ISO
protein:decreased expression:plasma
RGD
PMID:20213923
RGD:6483586
NCBI chr 6:110,547,165...110,557,747
Ensembl chr 6:104,816,104...104,826,685
G
M
Pgf
placental growth factor
ISO
protein:decreased expression:plasma
RGD
PMID:20213923
RGD:6483586
NCBI chr12:85,213,413...85,224,087
Ensembl chr12:85,213,409...85,224,564
G
H
PGF
placental growth factor
IEP
protein:decreased expression:plasma
RGD
PMID:20213923
RGD:6483586
NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626
G
N
Pim1
Pim-1 proto-oncogene, serine/threonine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23565217
NCBI chrNW_004624754:20,810,398...20,815,182
Ensembl chrNW_004624754:20,808,701...20,815,206
G
G
PIM1
Pim-1 proto-oncogene, serine/threonine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23565217
NCBI chr17:34,968,661...34,973,920
Ensembl chr17:34,968,429...34,973,760
G
P
PIM1
Pim-1 proto-oncogene, serine/threonine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23565217
NCBI chr 7:32,788,246...32,793,882
Ensembl chr 7:32,788,291...32,793,878
G
S
Pim1
Pim-1 proto-oncogene, serine/threonine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23565217
NCBI chrNW_004936476:22,295,023...22,300,155
Ensembl chrNW_004936476:22,295,021...22,300,161
G
D
PIM1
Pim-1 proto-oncogene, serine/threonine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23565217
NCBI chr12:6,213,504...6,217,933
Ensembl chr12:6,211,867...6,217,933
G
B
PIM1
Pim-1 proto-oncogene, serine/threonine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23565217
NCBI chr 6:36,730,669...36,735,954
G
C
Pim1
Pim-1 proto-oncogene, serine/threonine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23565217
NCBI chrNW_004955437:5,940,825...5,945,367
Ensembl chrNW_004955437:5,942,106...5,945,431
G
R
Pim1
Pim-1 proto-oncogene, serine/threonine kinase
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23565217
NCBI chr20:7,556,496...7,560,747
Ensembl chr20:7,554,921...7,559,174
G
M
Pim1
proviral integration site 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:23565217
NCBI chr17:29,709,759...29,715,085
Ensembl chr17:29,709,727...29,715,086
G
H
PIM1
Pim-1 proto-oncogene, serine/threonine kinase
EXP
CTD Direct Evidence: marker/mechanism
CTD
PMID:23565217
NCBI chr 6:37,170,152...37,175,428
Ensembl chr 6:37,170,152...37,175,428
G
N
Retn
resistin
ISO
protein:increased expression:plasma
RGD
PMID:20178460
RGD:7207160
NCBI chrNW_004624828:735,562...737,166
Ensembl chrNW_004624828:735,503...737,166
G
G
RETN
resistin
ISO
protein:increased expression:plasma
RGD
PMID:20178460
RGD:7207160
NCBI chr 6:7,154,771...7,156,459
Ensembl chr 6:7,155,337...7,156,505
G
P
RETN
resistin
ISO
protein:increased expression:plasma
RGD
PMID:20178460
RGD:7207160
NCBI chr 2:71,484,164...71,485,577
Ensembl chr 2:71,484,169...71,485,616
G
S
Retn
resistin
ISO
protein:increased expression:plasma
RGD
PMID:20178460
RGD:7207160
NCBI chrNW_004936588:4,705,295...4,706,653
Ensembl chrNW_004936588:4,705,119...4,706,656
G
D
RETN
resistin
ISO
protein:increased expression:plasma
RGD
PMID:20178460
RGD:7207160
NCBI chr20:52,434,148...52,435,627
Ensembl chr20:52,434,271...52,435,624
G
B
RETN
resistin
ISO
protein:increased expression:plasma
RGD
PMID:20178460
RGD:7207160
NCBI chr19:6,958,536...6,960,032
Ensembl chr19:7,812,942...7,814,909
G
C
Retn
resistin
ISO
protein:increased expression:plasma
RGD
PMID:20178460
RGD:7207160
NCBI chrNW_004955563:1,607,814...1,609,273
Ensembl chrNW_004955563:1,607,814...1,609,273
G
R
Retn
resistin
ISO
protein:increased expression:plasma
RGD
PMID:20178460
RGD:7207160
NCBI chr12:6,508,653...6,511,115
Ensembl chr12:1,710,881...1,712,620
G
M
Retn
resistin
ISO
protein:increased expression:plasma
RGD
PMID:20178460
RGD:7207160
NCBI chr 8:3,705,770...3,709,818
Ensembl chr 8:3,705,770...3,710,110
G
H
RETN
resistin
IEP
protein:increased expression:plasma
RGD
PMID:20178460
RGD:7207160
NCBI chr19:7,669,049...7,670,455
Ensembl chr19:7,669,049...7,670,455
G
N
Tlr1
toll like receptor 1
susceptibility
ISO
DNA:snp:cds:p.S602I (human)
RGD
PMID:19543401
RGD:7246906
NCBI chrNW_004624840:7,287,772...7,349,282
Ensembl chrNW_004624840:7,287,781...7,290,162
G
G
TLR1
toll like receptor 1
susceptibility
ISO
DNA:snp:cds:p.S602I (human)
RGD
PMID:19543401
RGD:7246906
NCBI chr27:11,482,307...11,490,847
Ensembl chr27:11,488,294...11,490,654
G
P
TLR1
toll like receptor 1
susceptibility
ISO
DNA:snp:cds:p.S602I (human)
RGD
PMID:19543401
RGD:7246906
NCBI chr 8:30,147,600...30,155,454
Ensembl chr 8:30,147,624...30,155,466
G
S
Tlr1
toll like receptor 1
susceptibility
ISO
DNA:snp:cds:p.S602I (human)
RGD
PMID:19543401
RGD:7246906
NCBI chrNW_004936482:6,582,430...6,591,128
Ensembl chrNW_004936482:6,582,584...6,584,971
G
D
TLR1
toll like receptor 1
susceptibility
ISO
DNA:snp:cds:p.S602I (human)
RGD
PMID:19543401
RGD:7246906
NCBI chr 3:73,504,359...73,544,822
Ensembl chr 3:73,539,715...73,544,624
G
B
TLR1
toll like receptor 1
susceptibility
ISO
DNA:snp:cds:p.S602I (human)
RGD
PMID:19543401
RGD:7246906
NCBI chr 4:33,119,485...33,133,541
Ensembl chr 4:38,979,006...38,981,366
G
C
Tlr1
toll like receptor 1
susceptibility
ISO
DNA:snp:cds:p.S602I (human)
RGD
PMID:19543401
RGD:7246906
NCBI chrNW_004955443:8,442,419...8,450,318
Ensembl chrNW_004955443:8,447,956...8,450,382
G
R
Tlr1
toll-like receptor 1
susceptibility
ISO
DNA:snp:cds:p.S602I (human)
RGD
PMID:19543401
RGD:7246906
NCBI chr14:43,737,761...43,750,389
Ensembl chr14:43,384,932...43,397,125
G
M
Tlr1
toll-like receptor 1
susceptibility
ISO
DNA:snp:cds:p.S602I (human)
RGD
PMID:19543401
RGD:7246906
NCBI chr 5:65,082,023...65,090,945
Ensembl chr 5:65,082,022...65,090,906
G
H
TLR1
toll like receptor 1
susceptibility
IAGP
DNA:snp:cds:p.S602I (human)
RGD
PMID:19543401
RGD:7246906
NCBI chr 4:38,787,569...38,805,644
Ensembl chr 4:38,787,555...38,856,817
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
M
Cxcl15
C-X-C motif chemokine ligand 15
susceptibility
ISO
DNA:SNP:promoter:g.-251T>A (rs4073) (human)
RGD
PMID:22325052
RGD:7207860
NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
G
N
Cxcl8
C-X-C motif chemokine ligand 8
susceptibility
ISO
DNA:SNP:promoter:g.-251T>A (rs4073) (human)
RGD
PMID:22325052
RGD:7207860
NCBI chrNW_004624730:1,744,097...1,747,206
Ensembl chrNW_004624730:1,743,916...1,747,293
G
G
CXCL8
C-X-C motif chemokine ligand 8
susceptibility
ISO
DNA:SNP:promoter:g.-251T>A (rs4073) (human)
RGD
PMID:22325052
RGD:7207860
NCBI chr 7:22,202,497...22,205,730
Ensembl chr 7:22,202,527...22,204,068
G
P
CXCL8
C-X-C motif chemokine ligand 8
susceptibility
ISO
DNA:SNP:promoter:g.-251T>A (rs4073) (human)
RGD
PMID:22325052
RGD:7207860
NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861
G
D
CXCL8
C-X-C motif chemokine ligand 8
susceptibility
ISO
DNA:SNP:promoter:g.-251T>A (rs4073) (human)
RGD
PMID:22325052
RGD:7207860
NCBI chr13:62,435,035...62,438,354
Ensembl chr13:62,434,422...62,438,354
G
B
CXCL8
C-X-C motif chemokine ligand 8
susceptibility
ISO
DNA:SNP:promoter:g.-251T>A (rs4073) (human)
RGD
PMID:22325052
RGD:7207860
NCBI chr 4:50,452,857...50,456,015
Ensembl chr 4:56,286,708...56,288,083
G
C
Cxcl8
C-X-C motif chemokine ligand 8
susceptibility
ISO
DNA:SNP:promoter:g.-251T>A (rs4073) (human)
RGD
PMID:22325052
RGD:7207860
NCBI chrNW_004955474:247,326...250,355
Ensembl chrNW_004955474:241,501...250,643
G
H
CXCL8
C-X-C motif chemokine ligand 8
susceptibility
IAGP
DNA:SNP:promoter:g.-251T>A (rs4073) (human)
RGD
PMID:22325052
RGD:7207860
NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
G
P
CXCR2
C-X-C motif chemokine receptor 2
susceptibility
ISO
DNA:polymorphism:3' utr:1208C>T (human)
RGD
PMID:22325052
RGD:7207860
NCBI chr15:120,219,657...120,230,203
G
D
CXCR2
C-X-C motif chemokine receptor 2
susceptibility
ISO
DNA:polymorphism:3' utr:1208C>T (human)
RGD
PMID:22325052
RGD:7207860
NCBI chr37:24,831,351...24,846,387
Ensembl chr37:24,843,171...24,844,247
G
B
CXCR2
C-X-C motif chemokine receptor 2
susceptibility
ISO
DNA:polymorphism:3' utr:1208C>T (human)
RGD
PMID:22325052
RGD:7207860
NCBI chr2B:105,387,198...105,400,533
Ensembl chr2B:223,997,066...223,998,148
G
R
Cxcr2
C-X-C motif chemokine receptor 2
susceptibility
ISO
DNA:polymorphism: :1208C>T (human)
RGD
PMID:22325052
RGD:7207860
NCBI chr 9:83,178,645...83,185,017
Ensembl chr 9:75,729,115...75,739,425
G
M
Cxcr2
C-X-C motif chemokine receptor 2
susceptibility
ISO
DNA:polymorphism:3' utr:1208C>T (human)
RGD
PMID:22325052
RGD:7207860
NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405
G
H
CXCR2
C-X-C motif chemokine receptor 2
susceptibility
IAGP
DNA:polymorphism:3' utr:1208C>T (human)
RGD
PMID:22325052
RGD:7207860
NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251
G
S
LOC101964975
interleukin-8
susceptibility
ISO
DNA:SNP:promoter:g.-251T>A (rs4073) (human)
RGD
PMID:22325052
RGD:7207860
NCBI chrNW_004936598:1,779,471...1,781,353
Ensembl chrNW_004936598:1,779,471...1,781,353
G
G
LOC103217855
C-X-C chemokine receptor type 2
susceptibility
ISO
DNA:polymorphism:3' utr:1208C>T (human)
RGD
PMID:22325052
RGD:7207860
NCBI chr10:104,012,906...104,025,599
Ensembl chr10:104,022,811...104,023,893
G
N
Rbp4
retinol binding protein 4
ISO
protein:decreased expression:blood plasma (human)
RGD
PMID:20163326
RGD:329853301
NCBI chrNW_004624737:4,795,054...4,800,830
Ensembl chrNW_004624737:4,791,628...4,800,989
G
G
RBP4
retinol binding protein 4
ISO
protein:decreased expression:blood plasma (human)
RGD
PMID:20163326
RGD:329853301
NCBI chr 9:86,831,042...86,840,668
Ensembl chr 9:86,830,957...86,840,250
G
P
RBP4
retinol binding protein 4
ISO
protein:decreased expression:blood plasma (human)
RGD
PMID:20163326
RGD:329853301
NCBI chr14:105,037,360...105,044,552
Ensembl chr14:105,037,464...105,044,765
G
S
Rbp4
retinol binding protein 4
ISO
protein:decreased expression:blood plasma (human)
RGD
PMID:20163326
RGD:329853301
NCBI chrNW_004936601:1,401,215...1,410,195
Ensembl chrNW_004936601:1,402,691...1,410,208
G
D
RBP4
retinol binding protein 4
ISO
protein:decreased expression:blood plasma (human)
RGD
PMID:20163326
RGD:329853301
NCBI chr28:7,822,936...7,830,735
Ensembl chr28:7,822,944...7,830,750
G
B
RBP4
retinol binding protein 4
ISO
protein:decreased expression:blood plasma (human)
RGD
PMID:20163326
RGD:329853301
NCBI chr10:90,337,879...90,347,530
Ensembl chr10:93,848,166...93,857,887
G
C
Rbp4
retinol binding protein 4
ISO
protein:decreased expression:blood plasma (human)
RGD
PMID:20163326
RGD:329853301
NCBI chrNW_004955507:112,342...120,050
Ensembl chrNW_004955507:108,669...120,584
G
R
Rbp4
retinol binding protein 4
ISO
protein:decreased expression:blood plasma (human)
RGD
PMID:20163326
RGD:329853301
NCBI chr 1:245,306,349...245,313,551
Ensembl chr 1:235,893,917...235,901,399
G
M
Rbp4
retinol binding protein 4, plasma
ISO
protein:decreased expression:blood plasma (human)
RGD
PMID:20163326
RGD:329853301
NCBI chr19:38,105,068...38,113,769
Ensembl chr19:38,105,077...38,113,729
G
H
RBP4
retinol binding protein 4
IEP
protein:decreased expression:blood plasma (human)
RGD
PMID:20163326
RGD:329853301
NCBI chr10:93,591,694...93,601,744
Ensembl chr10:93,591,687...93,601,744
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