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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:pyelitis
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Accession:DOID:2744 term browser browse the term
Definition:Inflammation of the KIDNEY PELVIS and KIDNEY CALICES where urine is collected before discharge, but does not involve the renal parenchyma (the NEPHRONS) where urine is processed.
Synonyms:primary_id: MESH:D011702;   RDO:0006445
 xref: NCI:C34964
For additional species annotation, visit the Alliance of Genome Resources.



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acute pyelonephritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcr2 C-X-C motif chemokine receptor 2 susceptibility ISO DNA:polymorphism: :1208C>T (human) RGD PMID:22325052 RGD:7207860 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
JBrowse link
pyelonephritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO protein:decreased expression:kidney, brush border epithelial cell (human) RGD PMID:10504496 RGD:8158033 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor ISO RGD PMID:19205372 RGD:6904156 NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331
JBrowse link
G B2m beta-2 microglobulin IEP protein:increased expression:urine RGD PMID:21797109 RGD:6482315 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Bmp7 bone morphogenetic protein 7 IEP protein:decreased expression:kidney RGD PMID:16034630 RGD:2289039 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
JBrowse link
G Calca calcitonin-related polypeptide alpha ISO RGD PMID:15286264 RGD:7205498 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Cfb complement factor B ISO associated with pregnancy complications;protein:increased activity:plasma RGD PMID:20218820 RGD:7242756 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
JBrowse link
G Crp C-reactive protein IEP RGD PMID:21797109 RGD:6482315 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 ISO DNA:SNP: :2608G>C (human)
DNA:mutations, polymorphisms: :multiple
RGD PMID:22325052 PMID:17786197 RGD:7207860, RGD:7207864 NCBI chr 9:75,768,124...75,771,122
Ensembl chr 9:75,766,770...75,771,084
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO RGD PMID:21814172 RGD:7257675 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
JBrowse link
G Cyb5a cytochrome b5 type A IEP RGD PMID:9848217 RGD:1599663 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO protein:increased expression:urine (human) RGD PMID:8640042 RGD:6907372 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il3 interleukin 3 IEP mRNA:increased expression:kidney RGD PMID:18214547 RGD:2317665 NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
JBrowse link
G Pgf placental growth factor ISO protein:decreased expression:plasma RGD PMID:20213923 RGD:6483586 NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23565217 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
JBrowse link
G Retn resistin ISO protein:increased expression:plasma RGD PMID:20178460 RGD:7207160 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
JBrowse link
G Tlr1 toll-like receptor 1 susceptibility ISO DNA:snp:cds:p.S602I (human) RGD PMID:19543401 RGD:7246906 NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18133
    disease of anatomical entity 17503
      Immune & Inflammatory Diseases 5178
        Inflammation 2799
          nephritis 454
            pyelitis 16
              Pyelocystitis 0
              pyelonephritis + 16
              pyeloureteritis cystica 0
Path 2
Term Annotations click to browse term
  disease 18133
    disease of anatomical entity 17503
      Urogenital Diseases 4700
        urinary system disease 2386
          kidney disease 2158
            nephritis 454
              pyelitis 16
                Pyelocystitis 0
                pyelonephritis + 16
                pyeloureteritis cystica 0
paths to the root