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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:pyelitis
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Accession:DOID:2744 term browser browse the term
Definition:Inflammation of the KIDNEY PELVIS and KIDNEY CALICES where urine is collected before discharge, but does not involve the renal parenchyma (the NEPHRONS) where urine is processed.
Synonyms:primary_id: MESH:D011702;   RDO:0006445
 xref: NCI:C34964
For additional species annotation, visit the Alliance of Genome Resources.


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acute pyelonephritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cxcr2 C-X-C motif chemokine receptor 2 susceptibility ISO DNA:polymorphism: :1208C>T (human) RGD PMID:22325052 RGD:7207860 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
pyelonephritis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO protein:decreased expression:kidney, brush border epithelial cell (human) RGD PMID:10504496 RGD:8158033 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ambp alpha-1-microglobulin/bikunin precursor ISO RGD PMID:19205372 RGD:6904156 NCBI chr 5:78,975,690...78,986,021
Ensembl chr 5:78,975,678...78,985,990
JBrowse link
G B2m beta-2 microglobulin IEP protein:increased expression:urine RGD PMID:21797109 RGD:6482315 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Bmp7 bone morphogenetic protein 7 IEP protein:decreased expression:kidney RGD PMID:16034630 RGD:2289039 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Calca calcitonin-related polypeptide alpha ISO RGD PMID:15286264 RGD:7205498 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Cfb complement factor B ISO associated with pregnancy complications;protein:increased activity:plasma RGD PMID:20218820 RGD:7242756 NCBI chr20:4,536,206...4,542,073
Ensembl chr20:4,536,203...4,561,066
Ensembl chr20:4,536,203...4,561,066
JBrowse link
G Crp C-reactive protein IEP RGD PMID:21797109 RGD:6482315 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 ISO DNA:SNP: :2608G>C (human)
DNA:mutations, polymorphisms: :multiple
RGD PMID:22325052, PMID:17786197 RGD:7207860, RGD:7207864 NCBI chr 9:81,466,430...81,469,299
Ensembl chr 9:81,466,332...81,469,274
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO RGD PMID:21814172 RGD:7257675 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Cyb5a cytochrome b5 type A IEP RGD PMID:9848217 RGD:1599663 NCBI chr18:81,694,818...81,726,821
Ensembl chr18:81,694,808...81,726,821
JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO protein:increased expression:urine (human) RGD PMID:8640042 RGD:6907372 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il3 interleukin 3 IEP mRNA:increased expression:kidney RGD PMID:18214547 RGD:2317665 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973
JBrowse link
G Pgf placental growth factor ISO protein:decreased expression:plasma RGD PMID:20213923 RGD:6483586 NCBI chr 6:108,994,016...109,004,598
Ensembl chr 6:108,994,018...109,004,598
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23565217 NCBI chr20:8,165,423...8,169,557
Ensembl chr20:8,165,307...8,169,555
JBrowse link
G Retn resistin ISO protein:increased expression:plasma RGD PMID:20178460 RGD:7207160 NCBI chr12:2,201,909...2,203,649
Ensembl chr12:2,201,891...2,204,249
JBrowse link
G Tlr1 toll-like receptor 1 susceptibility ISO DNA:snp:cds:p.S602I (human) RGD PMID:19543401 RGD:7246906 NCBI chr14:45,062,662...45,065,014
Ensembl chr14:45,062,662...45,081,991
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  disease 16092
    disease of anatomical entity 15341
      Immune & Inflammatory Diseases 3577
        Inflammation 2229
          nephritis 425
            pyelitis 16
              Pyelocystitis 0
              pyelonephritis + 16
              pyeloureteritis cystica 0
Path 2
Term Annotations click to browse term
  disease 16092
    disease of anatomical entity 15341
      Urogenital Diseases 4143
        urinary system disease 2071
          kidney disease 1856
            nephritis 425
              pyelitis 16
                Pyelocystitis 0
                pyelonephritis + 16
                pyeloureteritis cystica 0
paths to the root