CXCR2 (C-X-C motif chemokine receptor 2) - Rat Genome Database

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Gene: CXCR2 (C-X-C motif chemokine receptor 2) Sus scrofa
Analyze
Symbol: CXCR2
Name: C-X-C motif chemokine receptor 2
RGD ID: 13842626
Description: ENCODES a protein that exhibits chemokine receptor activity (ortholog); G protein-coupled receptor activity (ortholog); interleukin-8 receptor activity (ortholog); INVOLVED IN acute inflammatory response to antigenic stimulus (ortholog); cell surface receptor signaling pathway (ortholog); cellular defense response (ortholog); ASSOCIATED WITH Acute Lung Injury (ortholog); acute pyelonephritis (ortholog); allergic disease (ortholog); FOUND IN cell surface (ortholog); mast cell granule (ortholog); membrane (ortholog); INTERACTS WITH prostaglandin F2alpha; zearalenone
Type: protein-coding
RefSeq Status: MODEL
Also known as: C-X-C chemokine receptor type 2; IL8R2; IL8RB; interleukin 8 receptor 2; interleukin 8 receptor, beta
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.115120,219,657 - 120,230,203 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215133,275,203 - 133,286,266 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:14681463   PMID:15912099  


Genomics

Comparative Map Data
CXCR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.115120,219,657 - 120,230,203 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215133,275,203 - 133,286,266 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CXCR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2218,125,289 - 218,137,251 (+)EnsemblGRCh38hg38GRCh38
GRCh382218,125,294 - 218,137,253 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372218,990,017 - 219,001,974 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362218,698,991 - 218,710,220 (+)NCBINCBI36hg18NCBI36
Build 342218,816,251 - 218,827,481NCBI
Celera2212,756,449 - 212,768,411 (+)NCBI
Cytogenetic Map2q35NCBI
HuRef2210,842,767 - 210,854,732 (+)NCBIHuRef
CHM1_12218,996,503 - 219,008,469 (+)NCBICHM1_1
Cxcr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39174,193,153 - 74,200,405 (+)NCBIGRCm39mm39
GRCm39 Ensembl174,193,148 - 74,200,405 (+)Ensembl
GRCm38174,153,994 - 74,161,246 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl174,153,989 - 74,161,246 (+)EnsemblGRCm38mm10GRCm38
MGSCv37174,200,568 - 74,207,820 (+)NCBIGRCm37mm9NCBIm37
MGSCv36174,087,201 - 74,094,453 (+)NCBImm8
Celera174,715,354 - 74,722,423 (+)NCBICelera
Cytogenetic Map1C3NCBI
cM Map138.41NCBI
Cxcr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2975,729,493 - 75,735,868 (+)NCBI
Rnor_6.0 Ensembl981,427,730 - 81,434,102 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0981,427,275 - 81,435,065 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0981,193,442 - 81,199,814 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4973,470,943 - 73,477,315 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1973,617,924 - 73,624,297 (+)NCBI
Celera973,306,852 - 73,313,224 (+)NCBICelera
Cytogenetic Map9q33NCBI
CXCR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12B223,987,556 - 223,999,511 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B223,997,066 - 223,998,148 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02B105,387,198 - 105,400,533 (+)NCBIMhudiblu_PPA_v0panPan3
CXCR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13724,831,351 - 24,846,387 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3724,843,171 - 24,844,247 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3725,659,341 - 25,664,768 (+)NCBI
ROS_Cfam_1.03724,847,511 - 24,862,398 (+)NCBI
UMICH_Zoey_3.13724,760,631 - 24,766,058 (+)NCBI
UNSW_CanFamBas_1.03724,694,995 - 24,700,420 (+)NCBI
UU_Cfam_GSD_1.03724,714,358 - 24,719,785 (+)NCBI
LOC103217855
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110104,012,906 - 104,025,599 (+)NCBI
ChlSab1.1 Ensembl10104,022,811 - 104,023,893 (+)Ensembl
Vero_WHO_p1.0NW_02366604095,376,101 - 95,386,709 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 1
Low 7 3 2 3 3 2 2
Below cutoff 1 1 1 2 14 1

Sequence


Reference Sequences
RefSeq Acc Id: XM_021075280   ⟹   XP_020930939
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115120,219,708 - 120,230,203 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021075281   ⟹   XP_020930940
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115120,219,675 - 120,230,203 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021075282   ⟹   XP_020930941
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115120,220,337 - 120,230,203 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021075283   ⟹   XP_020930942
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115120,219,716 - 120,230,203 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021075284   ⟹   XP_020930943
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115120,219,657 - 120,230,203 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021075285   ⟹   XP_020930944
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.115120,220,338 - 120,230,203 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_020930943   ⟸   XM_021075284
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020930940   ⟸   XM_021075281
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020930939   ⟸   XM_021075280
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020930942   ⟸   XM_021075283
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_020930941   ⟸   XM_021075282
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_020930944   ⟸   XM_021075285
- Peptide Label: isoform X2
- Sequence:
Protein Domains
G_PROTEIN_RECEP_F1_2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000016184 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070017767 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000017144 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000017145 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000058145 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070029291 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000017622 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000017623 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000062963 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070035060 UniProtKB/TrEMBL
InterPro Chemokine_CXCR2 UniProtKB/TrEMBL
  Chemokine_CXCR_1/2 UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
NCBI Gene CXCR2 ENTREZGENE
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  INTRLEUKIN8R UniProtKB/TrEMBL
  INTRLEUKN8BR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
UniProt A0A4X1UJA0_PIG UniProtKB/TrEMBL
  F1SS03_PIG UniProtKB/TrEMBL
  F1SS04_PIG UniProtKB/TrEMBL