PIM1 (Pim-1 proto-oncogene, serine/threonine kinase) - Rat Genome Database

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Gene: PIM1 (Pim-1 proto-oncogene, serine/threonine kinase) Canis lupus familiaris
Analyze
Symbol: PIM1
Name: Pim-1 proto-oncogene, serine/threonine kinase
RGD ID: 12051160
Description: ENCODES a protein that exhibits ATP binding (ortholog); manganese ion binding (ortholog); protein serine/threonine kinase activator activity (ortholog); INVOLVED IN cellular detoxification (ortholog); negative regulation of apoptotic process (ortholog); negative regulation of DNA-binding transcription factor activity (ortholog); PARTICIPATES IN granulocyte-macrophage colony-stimulating factor signaling pathway; interleukin-3 signaling pathway; interleukin-5 signaling pathway; ASSOCIATED WITH allergic contact dermatitis (ortholog); Animal Disease Models (ortholog); Breast Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleolus (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: pim-1 oncogene; serine/threonine-protein kinase pim-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1126,213,504 - 6,217,933 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl126,211,867 - 6,217,933 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha126,231,727 - 6,236,155 (+)NCBI
ROS_Cfam_1.0126,677,872 - 6,682,310 (+)NCBI
UMICH_Zoey_3.1126,215,069 - 6,219,497 (+)NCBI
UNSW_CanFamBas_1.0126,296,443 - 6,300,872 (+)NCBI
UU_Cfam_GSD_1.0126,395,246 - 6,399,674 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
PIM1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1126,213,504 - 6,217,933 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl126,211,867 - 6,217,933 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha126,231,727 - 6,236,155 (+)NCBI
ROS_Cfam_1.0126,677,872 - 6,682,310 (+)NCBI
UMICH_Zoey_3.1126,215,069 - 6,219,497 (+)NCBI
UNSW_CanFamBas_1.0126,296,443 - 6,300,872 (+)NCBI
UU_Cfam_GSD_1.0126,395,246 - 6,399,674 (+)NCBI
PIM1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl637,170,152 - 37,175,428 (+)EnsemblGRCh38hg38GRCh38
GRCh38637,170,152 - 37,175,428 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37637,137,928 - 37,143,204 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36637,245,964 - 37,251,182 (+)NCBINCBI36hg18NCBI36
Build 34637,245,963 - 37,251,180NCBI
Celera638,693,003 - 38,698,282 (+)NCBI
Cytogenetic Map6p21.2NCBI
HuRef636,856,808 - 36,862,087 (+)NCBIHuRef
CHM1_1637,139,777 - 37,145,056 (+)NCBICHM1_1
Pim1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391729,709,759 - 29,715,085 (+)NCBIGRCm39mm39
GRCm39 Ensembl1729,709,727 - 29,715,086 (+)Ensembl
GRCm381729,490,785 - 29,496,111 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1729,490,753 - 29,496,112 (+)EnsemblGRCm38mm10GRCm38
MGSCv371729,627,990 - 29,632,410 (+)NCBIGRCm37mm9NCBIm37
MGSCv361729,217,824 - 29,222,468 (+)NCBImm8
Celera1730,034,650 - 30,039,059 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1715.38NCBI
Pim1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2207,554,921 - 7,559,174 (+)NCBI
Rnor_6.0 Ensembl208,165,307 - 8,169,555 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0208,165,423 - 8,169,557 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02010,364,285 - 10,368,419 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4207,817,403 - 7,821,800 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1207,817,629 - 7,822,027 (+)NCBI
Celera209,096,543 - 9,100,794 (+)NCBICelera
Cytogenetic Map20p12NCBI
Pim1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554375,942,106 - 5,945,431 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554375,940,825 - 5,945,367 (-)NCBIChiLan1.0ChiLan1.0
PIM1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1637,923,556 - 37,928,841 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0636,730,669 - 36,735,954 (+)NCBIMhudiblu_PPA_v0panPan3
Pim1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494641,660,075 - 41,664,724 (+)NCBI
SpeTri2.0NW_00493647622,295,023 - 22,300,155 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIM1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl732,788,005 - 32,793,880 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1732,788,246 - 32,793,882 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2737,691,993 - 37,697,470 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PIM1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11734,968,661 - 34,973,920 (-)NCBI
ChlSab1.1 Ensembl1734,968,429 - 34,973,760 (-)Ensembl
Vero_WHO_p1.0NW_02366604437,109,813 - 37,115,081 (+)NCBI
Pim1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475420,810,398 - 20,815,182 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 1 2 1 6 1 6 8 6 2
Low 4 5 20 5 5 6 12 4 4
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000002258   ⟹   ENSCAFP00000002094
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl126,211,867 - 6,217,933 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000059562   ⟹   ENSCAFP00000062108
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl126,211,867 - 6,217,933 (+)Ensembl
RefSeq Acc Id: NM_001146177   ⟹   NP_001139649
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1126,213,504 - 6,217,933 (+)NCBI
Dog10K_Boxer_Tasha126,231,727 - 6,236,155 (+)NCBI
ROS_Cfam_1.0126,677,872 - 6,682,310 (+)NCBI
UMICH_Zoey_3.1126,215,069 - 6,219,497 (+)NCBI
UNSW_CanFamBas_1.0126,296,443 - 6,300,872 (+)NCBI
UU_Cfam_GSD_1.0126,395,246 - 6,399,674 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001139649 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001139649   ⟸   NM_001146177
- Sequence:
RefSeq Acc Id: ENSCAFP00000062108   ⟸   ENSCAFT00000059562
RefSeq Acc Id: ENSCAFP00000002094   ⟸   ENSCAFT00000002258
Protein Domains
Protein kinase

Promoters
RGD ID:13685405
Promoter ID:EPDNEW_C3475
Type:single initiation site
Name:PIM1_1
Description:serine/threonine-protein kinase pim-1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1126,212,593 - 6,212,653EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000001448 Ensembl
NCBI Gene PIM1 ENTREZGENE