Cxcr1 (C-X-C motif chemokine receptor 1) - Rat Genome Database

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Gene: Cxcr1 (C-X-C motif chemokine receptor 1) Chinchilla lanigera
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Symbol: Cxcr1
Name: C-X-C motif chemokine receptor 1
RGD ID: 9035385
Description: ENCODES a protein that exhibits interleukin-8 binding (ortholog); interleukin-8 receptor activity (ortholog); INVOLVED IN cell surface receptor signaling pathway (ortholog); receptor internalization (ortholog); ASSOCIATED WITH alacrima, achalasia, and impaired intellectual development syndrome (ortholog); cerebrotendinous xanthomatosis (ortholog); cholangiocarcinoma (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: C-X-C chemokine receptor type 1; chemokine (C-X-C motif) receptor 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545315,194,205 - 15,195,272 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545315,181,027 - 15,196,224 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cxcr1Chinchillaalacrima, achalasia, and impaired intellectual development syndrome  ISOCXCR1 (Homo sapiens)8554872ClinVar Annotator: match by term: Alacrima more ...ClinVarPMID:28492532
Cxcr1Chinchillacerebrotendinous xanthomatosis  ISOCXCR1 (Homo sapiens)8554872ClinVar Annotator: match by term: Cerebrotendinous XanthomatosisClinVarPMID:28492532
Cxcr1Chinchillacholangiocarcinoma  ISOCXCR1 (Homo sapiens)8554872ClinVar Annotator: match by term: CholangiocarcinomaClinVarPMID:18550579
Cxcr1Chinchillahuman immunodeficiency virus infectious disease  ISOCXCR1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:18550579 more ...
Cxcr1ChinchillaNeurodevelopmental Disorders  ISOCXCR1 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
Cxcr1Chinchillaparoxysmal nonkinesigenic dyskinesia 1  ISOCXCR1 (Homo sapiens)8554872ClinVar Annotator: match by term: Paroxysmal nonkinesigenic dyskinesiaClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cxcr1Chinchillaulcerative colitis  ISOCXCR1 (Homo sapiens)9068941CTD Direct Evidence: marker/mechanismCTDPMID:21297633
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cxcr1Chinchillahuman immunodeficiency virus infectious disease  ISOCXCR1 (Homo sapiens)7240710 OMIM 


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cxcr1Chinchillacell surface receptor signaling pathway involved_inISOCXCR1 (Homo sapiens)9068941 PMID:10734056UniProtPMID:10734056
Cxcr1Chinchillareceptor internalization involved_inISOCXCR1 (Homo sapiens)9068941 PMID:10734056UniProtPMID:10734056

Molecular Function

  


#
Reference Title
Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
PMID:22301074   PMID:30032202  



Cxcr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545315,194,205 - 15,195,272 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545315,181,027 - 15,196,224 (+)NCBIChiLan1.0ChiLan1.0
CXCR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382218,162,841 - 218,166,962 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2218,162,841 - 218,166,962 (-)EnsemblGRCh38hg38GRCh38
GRCh372219,027,564 - 219,031,685 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362218,735,813 - 218,739,961 (-)NCBINCBI36Build 36hg18NCBI36
Build 342218,853,075 - 218,857,222NCBI
Celera2212,794,153 - 212,798,301 (-)NCBICelera
Cytogenetic Map2q35NCBI
HuRef2210,880,311 - 210,884,459 (-)NCBIHuRef
CHM1_12219,034,054 - 219,038,202 (-)NCBICHM1_1
T2T-CHM13v2.02218,648,531 - 218,652,652 (-)NCBIT2T-CHM13v2.0
Cxcr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39174,228,862 - 74,233,867 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl174,230,944 - 74,233,790 (-)EnsemblGRCm39 Ensembl
GRCm38174,191,785 - 74,194,708 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl174,191,785 - 74,194,631 (-)EnsemblGRCm38mm10GRCm38
MGSCv37174,238,359 - 74,241,205 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36174,124,992 - 74,126,442 (-)NCBIMGSCv36mm8
Celera174,753,154 - 74,755,998 (-)NCBICelera
Cytogenetic Map1C3NCBI
cM Map138.44NCBI
Cxcr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8983,216,040 - 83,220,225 (-)NCBIGRCr8
mRatBN7.2975,766,894 - 75,771,079 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl975,766,770 - 75,771,084 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx984,221,913 - 84,222,962 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0989,350,842 - 89,351,891 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0987,737,061 - 87,738,110 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0981,466,430 - 81,469,299 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl981,466,332 - 81,469,274 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0981,232,019 - 81,235,417 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4973,510,488 - 73,511,537 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1973,657,469 - 73,658,519 (-)NCBI
Celera973,345,732 - 73,346,781 (-)NCBICelera
Cytogenetic Map9q33NCBI
CXCR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213120,802,384 - 120,862,522 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B120,817,351 - 120,877,489 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B105,429,576 - 105,433,243 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B224,027,533 - 224,031,675 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B224,028,838 - 224,029,890 (-)Ensemblpanpan1.1panPan2
Cxcr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303174,371,818 - 174,373,425 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936569715,129 - 716,181 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936569715,129 - 716,187 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CXCR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110104,052,709 - 104,056,388 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10104,053,544 - 104,054,620 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604095,344,477 - 95,348,616 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cxcr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248236,859,356 - 6,860,426 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248236,857,649 - 6,861,219 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSCLAT00000026265   ⟹   ENSCLAP00000025959
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495545315,194,205 - 15,195,272 (+)Ensembl
RefSeq Acc Id: XM_005395665   ⟹   XP_005395722
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495545315,190,090 - 15,196,060 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013519957   ⟹   XP_013375411
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495545315,181,027 - 15,196,224 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013519958   ⟹   XP_013375412
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495545315,181,028 - 15,196,224 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013519959   ⟹   XP_013375413
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495545315,191,306 - 15,196,224 (+)NCBI
Sequence:
Protein RefSeqs XP_005395722 (Get FASTA)   NCBI Sequence Viewer  
  XP_013375411 (Get FASTA)   NCBI Sequence Viewer  
  XP_013375412 (Get FASTA)   NCBI Sequence Viewer  
  XP_013375413 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000025959
  ENSCLAP00000025959.1
RefSeq Acc Id: XP_005395722   ⟸   XM_005395665
- UniProtKB: A0A8C2WB81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013375411   ⟸   XM_013519957
- UniProtKB: A0A8C2WB81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013375412   ⟸   XM_013519958
- UniProtKB: A0A8C2WB81 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013375413   ⟸   XM_013519959
- UniProtKB: A0A8C2WB81 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000025959   ⟸   ENSCLAT00000026265


1 to 18 of 18 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCLAG00000018091 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000026265 ENTREZGENE
  ENSCLAT00000026265.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro Chemokine_CXCR_1/2 UniProtKB/TrEMBL
  GPCR1 UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
NCBI Gene Cxcr1 ENTREZGENE
PANTHER C-X-C CHEMOKINE RECEPTOR TYPE 1 UniProtKB/TrEMBL
  CELL ADHESION MOLECULE UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  INTRLEUKIN8R UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8C2WB81 ENTREZGENE, UniProtKB/TrEMBL
1 to 18 of 18 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Cxcr1  C-X-C motif chemokine receptor 1    chemokine (C-X-C motif) receptor 1  Symbol and/or name change 5135510 APPROVED