CALCA (calcitonin related polypeptide alpha) - Rat Genome Database

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Gene: CALCA (calcitonin related polypeptide alpha) Pan paniscus
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Symbol: CALCA
Name: calcitonin related polypeptide alpha
RGD ID: 12004212
Description: ENCODES a protein that exhibits calcitonin receptor binding (ortholog); identical protein binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN activation of adenylate cyclase activity (ortholog); activation of protein kinase activity (ortholog); adenylate cyclase-activating G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH Acute Necrotizing Pancreatitis (ortholog); amyotrophic lateral sclerosis (ortholog); Animal Disease Models (ortholog); FOUND IN axon (ortholog); cytoplasm (ortholog); extracellular region (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: calcitonin; calcitonin gene-related peptide 1
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11114,745,588 - 14,751,267 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1114,745,588 - 14,751,267 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01115,055,897 - 15,061,539 (-)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of adenylate cyclase activity  (ISO)
activation of protein kinase activity  (ISO)
adenylate cyclase-activating G protein-coupled receptor signaling pathway  (ISO)
aging  (ISO)
amylin receptor signaling pathway  (ISO)
artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure  (ISO)
calcitonin gene-related peptide receptor signaling pathway  (ISO)
cellular calcium ion homeostasis  (ISO)
cellular response to nerve growth factor stimulus  (ISO)
cellular response to tumor necrosis factor  (ISO)
detection of temperature stimulus involved in sensory perception of pain  (ISO)
embryo implantation  (ISO)
endothelial cell migration  (ISO)
endothelial cell proliferation  (ISO)
feeding behavior  (ISO)
G protein-coupled receptor internalization  (ISO)
inflammatory response  (ISO)
leukocyte cell-cell adhesion  (ISO)
monocyte chemotaxis  (ISO)
negative regulation of blood pressure  (ISO)
negative regulation of bone resorption  (ISO)
negative regulation of calcium ion transport into cytosol  (ISO)
negative regulation of nervous system process  (ISO)
negative regulation of ossification  (ISO)
negative regulation of osteoclast differentiation  (ISO)
negative regulation of smooth muscle contraction  (ISO)
negative regulation of transcription, DNA-templated  (ISO)
nervous system process involved in regulation of systemic arterial blood pressure  (ISO)
neuromuscular junction development  (ISO)
neuropeptide signaling pathway  (ISO)
positive regulation of cell adhesion  (ISO)
positive regulation of cytosolic calcium ion concentration  (ISO)
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway  (ISO)
positive regulation of interleukin-1 alpha production  (ISO)
positive regulation of interleukin-8 production  (ISO)
positive regulation of macrophage differentiation  (ISO)
positive regulation of ossification  (ISO)
protein phosphorylation  (ISO)
receptor internalization  (ISO)
regulation of blood pressure  (ISO)
regulation of cytosolic calcium ion concentration  (ISO)
regulation of heart contraction  (ISO)
regulation of heart rate  (ISO)
response to heat  (ISO)
response to pain  (ISO)
vasculature development  (ISO)
vasodilation  (ISO)

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
CALCA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11114,745,588 - 14,751,267 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1114,745,588 - 14,751,267 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01115,055,897 - 15,061,539 (-)NCBIMhudiblu_PPA_v0panPan3
CALCA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1114,966,668 - 14,972,351 (-)EnsemblGRCh38hg38GRCh38
GRCh381114,966,668 - 14,972,361 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371114,988,214 - 14,993,897 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361114,944,792 - 14,950,408 (-)NCBINCBI36hg18NCBI36
Build 341114,946,625 - 14,950,427NCBI
Celera1115,115,335 - 15,120,952 (-)NCBI
Cytogenetic Map11p15.2NCBI
HuRef1114,671,857 - 14,677,473 (-)NCBIHuRef
CHM1_11114,987,226 - 14,992,843 (-)NCBICHM1_1
Calca
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397114,225,223 - 114,236,145 (-)NCBIGRCm39mm39
GRCm39 Ensembl7114,230,713 - 114,235,592 (-)Ensembl
GRCm387114,625,981 - 114,636,910 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7114,631,478 - 114,636,357 (-)EnsemblGRCm38mm10GRCm38
MGSCv377121,774,992 - 121,779,871 (-)NCBIGRCm37mm9NCBIm37
MGSCv367114,422,640 - 114,427,439 (-)NCBImm8
Celera7114,584,937 - 114,589,792 (-)NCBICelera
Cytogenetic Map7F1NCBI
cM Map759.99NCBI
Calca
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21168,878,212 - 168,883,176 (-)NCBI
Rnor_6.0 Ensembl1184,184,020 - 184,188,911 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01184,184,018 - 184,188,922 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01191,158,061 - 191,162,954 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41172,686,168 - 172,691,061 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11172,824,299 - 172,827,127 (-)NCBI
Celera1166,711,610 - 166,716,491 (-)NCBICelera
RH 3.4 Map11317.6RGD
RH 2.0 Map1757.3RGD
Cytogenetic Map1q35NCBI
CRSP-3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12137,676,841 - 37,680,643 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2137,676,841 - 37,680,645 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2137,176,307 - 37,180,108 (+)NCBI
ROS_Cfam_1.02138,770,713 - 38,774,520 (+)NCBI
UNSW_CanFamBas_1.02137,993,320 - 37,997,114 (+)NCBI
UU_Cfam_GSD_1.02138,281,026 - 38,284,825 (+)NCBI
Calca
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494747,766,690 - 47,772,207 (+)NCBI
SpeTri2.0NW_0049365283,800,801 - 3,806,000 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CALCB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1244,043,135 - 44,048,651 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2247,248,414 - 47,253,904 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103239768
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1149,946,574 - 49,956,010 (+)NCBI
ChlSab1.1 Ensembl149,951,694 - 49,954,092 (+)Ensembl
Vero_WHO_p1.0NW_023666038147,447,203 - 147,453,110 (+)NCBI
Calca
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247666,764,388 - 6,771,396 (-)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000057830   ⟹   ENSPPAP00000034945
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1114,745,588 - 14,751,267 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000057834   ⟹   ENSPPAP00000034949
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1114,747,414 - 14,751,267 (-)Ensembl
RefSeq Acc Id: XM_003818194   ⟹   XP_003818242
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11114,747,414 - 14,751,267 (-)NCBI
Mhudiblu_PPA_v01115,057,316 - 15,061,539 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003818195   ⟹   XP_003818243
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11114,747,414 - 14,751,267 (-)NCBI
Mhudiblu_PPA_v01115,057,316 - 15,061,539 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008971459   ⟹   XP_008969707
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11114,747,414 - 14,750,613 (-)NCBI
Mhudiblu_PPA_v01115,057,316 - 15,061,037 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008971460   ⟹   XP_008969708
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11114,745,588 - 14,751,267 (-)NCBI
Mhudiblu_PPA_v01115,055,897 - 15,061,535 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003818242 (Get FASTA)   NCBI Sequence Viewer  
  XP_003818243 (Get FASTA)   NCBI Sequence Viewer  
  XP_008969707 (Get FASTA)   NCBI Sequence Viewer  
  XP_008969708 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_008969708   ⟸   XM_008971460
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_003818242   ⟸   XM_003818194
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_003818243   ⟸   XM_003818195
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008969707   ⟸   XM_008971459
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSPPAP00000034949   ⟸   ENSPPAT00000057834
RefSeq Acc Id: ENSPPAP00000034945   ⟸   ENSPPAT00000057830


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040307 Ensembl, ENTREZGENE
Ensembl Protein ENSPPAP00000034945 ENTREZGENE
  ENSPPAP00000034949 ENTREZGENE
NCBI Gene CALCA ENTREZGENE