Tnf (tumor necrosis factor) - Rat Genome Database

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Gene: Tnf (tumor necrosis factor) Rattus norvegicus
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Symbol: Tnf
Name: tumor necrosis factor
RGD ID: 3876
Description: Enables tumor necrosis factor receptor binding activity. Involved in several processes, including negative regulation of transport; positive regulation of cell communication; and positive regulation of macromolecule metabolic process. Acts upstream of or within positive regulation of interleukin-6 production. Located in external side of plasma membrane; extracellular space; and neuronal cell body. Is active in extracellular region. Used to study several diseases, including cerebrovascular disease (multiple); liver disease (multiple); peptic esophagitis; perinatal necrotizing enterocolitis; and periventricular leukomalacia. Biomarker of several diseases, including artery disease (multiple); brain disease (multiple); congestive heart failure (multiple); liver disease (multiple); and lung disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); lung disease (multiple); and skin disease (multiple). Orthologous to human TNF (tumor necrosis factor); PARTICIPATES IN pro-inflammatory cytokine mediated pathway; ceramide signaling pathway; Fc epsilon receptor mediated signaling pathway; INTERACTS WITH (+)-catechin; (+)-pilocarpine; (+)-taxifolin.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cachectin; LOC103694380; MGC124630; RATTNF; TNF-a; TNF-alpha; Tnfa; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor ligand superfamily member 2; tumor necrosis factor superfamily member 2; tumor necrosis factor superfamily, member 2; tumor necrosis factor-alpha; tumor necrosis factor-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Is Marker For: QTLs:   Bp144  
Candidate Gene For: Edcs3
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8203,626,685 - 3,629,303 (+)NCBIGRCr8
mRatBN7.2203,622,011 - 3,624,629 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl203,622,011 - 3,624,629 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,321,864 - 4,324,463 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0203,683,924 - 3,686,523 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,221,516 - 4,224,112 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0205,189,382 - 5,192,000 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,189,390 - 5,192,000 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,855,829 - 4,858,447 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,936,229 - 6,938,847 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,661,000 - 3,663,618 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera204,400,860 - 4,403,478 (-)NCBICelera
RH 3.4 Map20 RGD
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
acne  (ISO)
acquired immunodeficiency syndrome  (ISO)
Acute Coronary Syndrome  (IEP,ISO)
Acute Experimental Pancreatitis  (IEP)
Acute Hepatitis  (IMP,ISO)
acute kidney failure  (ISO)
Acute Liver Failure  (IEP,ISO)
Acute Lung Injury  (IEP,ISO)
acute myocardial infarction  (IEP)
adenocarcinoma  (ISO)
adult respiratory distress syndrome  (ISO)
Aggressive Fibromatosis  (ISO)
Albuminuria  (ISO)
alcoholic hepatitis  (IEP,ISO)
alcoholic liver cirrhosis  (ISO)
Alcoholic Liver Diseases  (IEP,IMP)
allergic bronchopulmonary aspergillosis  (ISO)
allergic contact dermatitis  (ISO)
allergic disease  (ISO)
Alveolar Bone Loss  (IEP)
Alzheimer's disease  (ISO)
Amebic Liver Abscess  (ISO)
amyloidosis  (ISO)
amyotrophic lateral sclerosis  (ISO)
amyotrophic lateral sclerosis type 1  (ISO)
anemia  (ISO)
Animal Disease Models  (ISO)
anogenital venereal wart  (ISO)
Anorexia  (ISO)
anterior uveitis  (ISO)
anthracosis  (ISO)
anthrax disease  (ISO)
anti-basement membrane glomerulonephritis  (IEP)
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis  (ISO)
anxiety disorder  (ISO)
aortic valve stenosis  (ISS)
aplastic anemia  (ISO)
Arsenic Poisoning  (ISO)
asbestosis  (ISO)
aspiration pneumonia  (IEP)
asthma  (ISO)
atherosclerosis  (ISO)
atopic dermatitis  (ISO)
atrial fibrillation  (ISO)
autistic disorder  (ISO)
autoimmune hepatitis  (ISO)
autoimmune thyroiditis  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
bacterial pneumonia  (ISO)
Behcet's disease  (ISO)
berylliosis  (ISO)
beta thalassemia  (ISO)
bilirubin metabolic disorder  (ISO)
Brain Contusion  (IEP)
brain edema  (ISO)
brain infarction  (IEP)
Brain Injuries  (IMP,ISO)
brain ischemia  (ISO)
breast adenocarcinoma  (ISO)
breast cancer  (ISO)
Breast Neoplasms  (ISO)
Bronchial Hyperreactivity  (ISO)
bronchiectasis  (ISO)
bronchopulmonary dysplasia  (ISO)
Burns  (IDA,ISO)
Cachexia  (IEP,ISO)
calcinosis  (ISO)
cardiac arrest  (IEP,ISO)
Cardiomegaly  (ISO)
cardiomyopathy  (IEP,ISO)
Cardiotoxicity  (ISO)
Cardiovascular Pregnancy Complications  (ISO)
Cardiovirus Infections  (ISO)
Cerebral Hemorrhage  (IEP)
cerebral infarction  (ISO)
cervical cancer  (ISO)
Chemical and Drug Induced Liver Injury  (IDA,IEP,IMP,ISO)
Chemically-Induced Disorders  (ISO)
chlamydia  (ISO)
cholestasis  (ISO)
cholesteatoma of middle ear  (ISO)
chorioamnionitis  (ISO)
Chronic Allograft Dysfunction  (IMP)
Chronic Hepatitis C  (ISO)
Chronic Intermittent Hypoxia  (IEP)
chronic obstructive pulmonary disease  (ISO)
cicatricial pemphigoid  (ISO)
cochlear disease  (IEP)
colitis  (ISO)
Colonic Neoplasms  (ISO)
Colorectal Neoplasms  (ISO)
congenital diaphragmatic hernia  (IEP)
congestive heart failure  (IEP,IMP,ISO,ISS)
Cor pulmonale  (ISO)
corneal ulcer  (ISO)
coronary artery disease  (ISO)
coronary restenosis  (ISO)
Coronavirus infectious disease  (ISO)
Cough  (ISO)
COVID-19  (ISO)
Coxsackievirus Infections  (ISO)
Crohn's disease  (IEP,ISO)
cryoglobulinemia  (ISO)
cutaneous leishmaniasis  (ISO)
cystic fibrosis  (ISO)
cystitis  (IEP)
Cytomegalovirus Infections  (ISO)
cytomegalovirus retinitis  (ISO)
degenerative disc disease  (ISO)
demyelinating disease  (ISO)
dermatitis  (ISO)
dermatitis herpetiformis  (ISO)
dermatomyositis  (ISO)
diabetic angiopathy  (ISO)
Diabetic Cardiomyopathies  (ISO)
Diabetic Nephropathies  (IDA,IEP,ISO)
diabetic neuropathy  (IEP)
diabetic retinopathy  (ISO)
Diaphragmatic Hernia  (ISO)
dilated cardiomyopathy  (ISO,ISS)
dilated cardiomyopathy 1H  (ISO)
disease by infectious agent  (ISO)
Disease Progression  (ISO)
disseminated intravascular coagulation  (ISO)
drug allergy  (ISO)
Drug Eruptions  (ISO)
Drug-Related Side Effects and Adverse Reactions  (ISO)
dry eye syndrome  (ISO)
Eales Disease  (ISO)
Edema  (ISO)
Emphysema  (ISO)
encephalitis  (IEP)
encephalomyelitis  (ISO)
end stage renal disease  (ISO)
endometriosis  (IDA,IEP,ISO)
endophthalmitis  (IEP)
Endotoxemia  (IDA,IEP,ISO)
epididymitis  (IEP)
epilepsy  (IEP)
erythema nodosum  (ISO)
Escherichia Coli Infections  (IEP)
esophagitis  (ISO)
essential hypertension  (ISO)
Experimental Arthritis  (IDA,IEP,ISO)
Experimental Autoimmune Encephalomyelitis  (IEP)
Experimental Autoimmune Neuritis  (IEP)
Experimental Colitis  (IEP,IMP)
Experimental Diabetes Mellitus  (IEP,ISO)
Experimental Liver Cirrhosis  (IEP,ISO)
Experimental Liver Neoplasms  (ISO)
Experimental Mammary Neoplasms  (ISO)
Experimental Neoplasms  (ISO)
Experimental Radiation Injuries  (ISO)
extrahepatic cholestasis  (ISO)
extrinsic allergic alveolitis  (ISO)
eye disease  (ISO)
Fanconi anemia  (ISO)
farmer's lung  (ISO)
Fever  (ISO)
Fibrosis  (ISO)
focal segmental glomerulosclerosis  (ISO)
Fungal Lung Diseases  (IEP)
gastric ulcer  (ISO)
gastritis  (IDA)
Gaucher's disease  (ISO)
glaucoma  (IEP,IMP,ISO)
glomerulonephritis  (ISO)
Graves ophthalmopathy  (ISO)
Graves' disease  (ISO)
Hearing Loss  (ISO)
Hearing Loss, Noise-Induced  (IEP)
Heart Injuries  (ISO)
heart valve disease  (ISS)
Heat Stroke  (ISO)
hemochromatosis  (ISO)
hemolytic-uremic syndrome  (ISO)
Hemorrhagic Shock  (IDA,ISO)
hepatic encephalopathy  (ISO)
hepatitis A  (ISO)
hepatitis B  (ISO)
hepatocellular carcinoma  (ISO)
hepatopulmonary syndrome  (IMP)
hepatorenal syndrome  (IEP)
hereditary hemorrhagic telangiectasia  (ISO)
herpes simplex virus keratitis  (ISO)
herpes zoster  (ISO)
hidradenitis suppurativa  (ISO)
high grade glioma  (ISO)
High-Frequency Hearing Loss  (ISO)
HIV Wasting Syndrome  (ISO)
human immunodeficiency virus infectious disease  (ISO)
Human Influenza  (ISO)
Hyperalgesia  (IDA,IEP,IMP,ISO)
hypercalcemia  (ISO)
hyperhomocysteinemia  (ISO)
hyperinsulinism  (ISO)
Hyperoxia  (ISO)
hypertension  (IAGP,IEP,IMP,ISO)
hypochromic microcytic anemia  (ISO)
hypoglycemia  (ISO)
Hypotension  (ISO)
Hypothermia  (ISO)
idiopathic pulmonary fibrosis  (ISO,ISS)
IgA glomerulonephritis  (ISO)
Immunodeficiency 127  (ISO)
impotence  (IEP)
inclusion body myopathy with Paget disease of bone and frontotemporal dementia  (ISO)
Inflammation  (IEP,ISO)
inflammatory bowel disease  (ISO,ISS)
Insulin Resistance  (IDA,IEP,IMP,ISO)
intermediate uveitis  (ISO)
interstitial cystitis  (ISO)
Intervertebral Disc Displacement  (IEP)
Intestinal Reperfusion Injury  (IEP)
intracranial aneurysm  (IMP)
Intracranial Hemorrhages  (ISO)
intrahepatic cholestasis of pregnancy  (ISO)
iron deficiency anemia  (ISO)
Kawasaki disease  (ISO)
keratoconjunctivitis sicca  (ISO)
kidney disease  (ISO)
Kidney Reperfusion Injury  (IEP,ISO)
labyrinthitis  (ISO)
leishmaniasis  (ISO)
leprosy  (ISO)
listeriosis  (ISO)
liver cirrhosis  (IEP,ISO)
liver disease  (ISO)
Liver Neoplasms  (ISO)
Liver Reperfusion Injury  (IEP,IMP,ISO)
localized scleroderma  (ISO)
low tension glaucoma  (ISO)
lung disease  (IEP,ISO)
Lung Injury  (IMP,ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
Lung Reperfusion Injury  (IMP,ISO)
lupus nephritis  (ISO)
lymphopenia  (ISO)
malaria  (ISO)
Manganese Poisoning  (ISO)
megacolon  (ISO)
melanoma  (ISO)
Meningeal Tuberculosis  (ISO)
metabolic dysfunction and alcohol associated liver disease  (IEP,ISO)
metabolic dysfunction-associated steatohepatitis  (IEP,ISO)
metabolic dysfunction-associated steatotic liver disease  (IEP,ISO)
Metabolic Syndrome  (IEP)
mevalonic aciduria  (ISO)
Micronuclei, Chromosome-Defective  (ISO)
middle cerebral artery infarction  (IEP,IMP,ISO)
Middle East respiratory syndrome  (ISO)
migraine  (ISO)
migraine without aura  (ISO)
mitochondrial myopathy  (ISO)
mixed connective tissue disease  (ISO)
mucocutaneous leishmaniasis  (ISO)
mucopolysaccharidosis VI  (IEP)
multiple myeloma  (ISO)
Multiple Organ Failure  (ISO)
multiple sclerosis  (ISO,ISS)
muscular atrophy  (ISO)
muscular dystrophy  (ISO)
Mycobacterium avium complex disease  (ISO)
Mycoplasma pneumoniae pneumonia  (ISO)
myelodysplastic syndrome  (ISO)
myocardial infarction  (IEP,ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (IEP)
myocardial stunning  (ISO)
myocarditis  (ISO)
myositis  (ISO)
Nasal Polyps  (ISO)
Nausea  (ISO)
Necrosis  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
Nerve Degeneration  (ISO)
nervous system disease  (ISO)
Neuralgia  (ISO)
neuroblastoma  (ISO)
Neurogenic Inflammation  (IDA,ISO)
neutropenia  (ISO)
obesity  (ISO)
obstructive sleep apnea  (ISO)
occupational asthma  (ISO)
open-angle glaucoma  (ISO)
oral squamous cell carcinoma  (IEP)
oral submucous fibrosis  (ISO)
Osteolysis  (ISO)
otitis media  (IEP,ISO)
Otitis Media with Effusion  (ISO)
ovarian cancer  (ISO)
Oxygen-Induced Retinopathy  (ISO)
Pain  (ISO)
Painful Neuropathy  (IMP,ISO)
pancreatic cancer  (ISO)
paracoccidioidomycosis  (ISO)
Parkinson's disease  (ISO)
Parkinsonism  (ISO)
Pediatric Crohn's Disease  (ISO)
Penetrating Wounds  (IEP)
peptic esophagitis  (IDA)
perinatal necrotizing enterocolitis  (IDA,IEP)
periodontitis  (IEP)
Peripheral Nerve Injuries  (IEP)
peritonitis  (IEP,ISO)
periventricular leukomalacia  (IDA,ISO)
Picornaviridae Infections  (ISO)
placenta disease  (ISO)
Plaque, Atherosclerotic  (ISO)
plasmacytoma  (ISO)
Plasmodium falciparum malaria  (ISO)
Pleural Effusion  (ISO)
pleurisy  (IDA,ISO)
Pneumococcal Meningitis  (IEP)
Pneumococcal Pneumonia  (ISO)
pneumonia  (ISO)
polymyositis  (ISO)
portal hypertension  (IEP,IMP)
Postmenopausal Osteoporosis  (ISO)
Postoperative Cognitive Dysfunction  (IEP)
pre-eclampsia  (IEP,ISO)
Pregnancy-Induced Hypertension  (IMP)
Premature Birth  (ISO)
primary biliary cholangitis  (ISO)
Primary Graft Dysfunction  (IEP)
primary open angle glaucoma  (ISO)
primary sclerosing cholangitis  (ISO)
prostate cancer  (ISO)
proteasome-associated autoinflammatory syndrome 1  (ISO)
Pseudomonas Infections  (ISO)
psoriasis  (ISO)
psoriatic arthritis  (ISO)
pulmonary edema  (ISO)
pulmonary emphysema  (ISO)
pulmonary fibrosis  (ISO)
pulmonary hypertension  (ISO)
pulmonary sarcoidosis  (ISO)
pulmonary tuberculosis  (ISO)
pustulosis of palm and sole  (ISO)
Radiation Pneumonitis  (ISO)
radiculopathy  (IEP)
Refractory Anemia  (ISO)
relapsing polychondritis  (ISO)
renal cell carcinoma  (ISO)
renal hypertension  (IEP)
Reperfusion Injury  (ISO)
respiratory allergy  (ISO)
respiratory syncytial virus infectious disease  (ISO)
respiratory system disease  (ISO)
Respiratory Tract Infections  (ISO)
Retina Reperfusion Injury  (IDA,IEP,IMP)
retinal artery occlusion  (ISO)
retinal detachment  (IDA,ISO)
retinal disease  (ISO)
rheumatoid arthritis  (ISO,ISS)
rhinitis  (IEP,ISO)
Rhinosinusitis  (ISO)
Right Ventricular Hypertrophy  (IEP)
root resorption  (IEP)
SAPHO syndrome  (ISO)
sarcoma  (ISO)
schizophrenia  (ISO)
sciatic neuropathy  (IEP)
scleritis  (ISO)
sensorineural hearing loss  (ISO)
Sepsis  (IDA,IEP,ISO)
septic arthritis  (ISO)
severe acute respiratory syndrome  (ISO)
Shock  (IEP)
sickle cell anemia  (ISO)
silicosis  (IEP,ISO)
Sjogren's syndrome  (IEP,ISO)
skin disease  (ISO)
small cell carcinoma  (ISO)
Soft Tissue Neoplasms  (ISO)
Spinal Cord Compression  (ISO)
Spinal Cord Injuries  (IMP)
Spine Osteoarthritis  (ISO)
spondyloarthropathy  (ISS)
Stable Angina  (ISO)
status epilepticus  (IEP,ISO)
steatotic liver disease  (ISO)
Stevens-Johnson syndrome  (ISO)
Stomach Neoplasms  (ISO)
Streptococcal Infections  (ISO)
Streptococcus pneumonia  (ISO)
Stroke  (IEP,ISO)
Subarachnoid Hemorrhage  (IEP,ISO)
Sudden Hearing Loss  (ISO)
Systemic Candidiasis  (ISO)
systemic lupus erythematosus  (ISO)
Tachycardia  (ISO)
Temporomandibular Joint Disorders  (ISO)
thalassemia  (ISO)
thrombocytopenia  (ISO)
thrombosis  (ISO)
Thyroid Neoplasms  (ISO)
Tinnitus  (IEP)
Tongue Neoplasms  (ISO)
toxic shock syndrome  (IEP,ISO)
trachoma  (ISO)
transient cerebral ischemia  (IDA,IEP)
transitional cell carcinoma  (ISO)
Transplant Rejection  (IEP,IMP,ISO)
traumatic brain injury  (ISO)
trichinosis  (ISO)
trigeminal neuralgia  (ISO)
tuberculosis  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (IMP,ISO)
typhoid fever  (ISO)
ulcerative colitis  (IEP,ISO)
ureteral obstruction  (IEP)
urinary bladder cancer  (ISO)
urticaria  (ISO)
uveitis  (IEP,ISO)
vascular dementia  (ISO)
vascular disease  (ISO)
Vascular System Injuries  (ISO)
Venous Thromboembolism  (ISO)
Ventricular Dysfunction  (ISO)
Viral Bronchiolitis  (ISO)
viral pneumonia  (ISO)
visceral leishmaniasis  (ISO)
visual epilepsy  (IDA)
vitiligo  (ISO)
Vogt-Koyanagi-Harada disease  (ISO)
Vulvar Vestibulitis  (ISO)
Weight Gain  (ISO)
Weill-Marchesani syndrome  (ISO)
Wilson disease  (ISO)
Wounds and Injuries  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-albicanol  (ISO)
(+)-artemisinin  (ISO)
(+)-catechin  (EXP,ISO)
(+)-epicatechin-3-O-gallate  (ISO)
(+)-isoborneol  (ISO)
(+)-pilocarpine  (EXP,ISO)
(+)-Pimaric acid  (ISO)
(+)-pinoresinol  (ISO)
(+)-sesamin  (ISO)
(+)-syringaresinol beta-D-glucoside  (ISO)
(+)-taxifolin  (EXP,ISO)
(+)-Tetrandrine  (EXP,ISO)
(-)-anisomycin  (ISO)
(-)-Arctigenin  (ISO)
(-)-citrinin  (ISO)
(-)-cotinine  (EXP)
(-)-demecolcine  (ISO)
(-)-ephedrine  (EXP,ISO)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(-)-hinokiresinol  (ISO)
(-)-matairesinol  (ISO)
(-)-quinic acid  (ISO)
(1->4)-beta-D-glucan  (ISO)
(20S)-ginsenoside Rg3  (EXP,ISO)
(20S)-ginsenoside Rh1  (ISO)
(2E,4E)-hexa-2,4-dienoic acid  (EXP)
(4-chloro-2-methylphenoxy)acetic acid  (ISO)
(4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid  (ISO)
(4Z,7Z,10Z,13Z,15E,19Z)-17-hydroxydocosahexaenoic acid  (ISO)
(5Z,8Z,11Z,13E)-15-HETE  (ISO)
(E)-roxithromycin  (EXP,ISO)
(E)-thiamethoxam  (EXP)
(R)-adrenaline  (EXP,ISO)
(R)-carnitine  (EXP)
(R)-linalyl acetate  (ISO)
(R)-lipoic acid  (EXP,ISO)
(R)-noradrenaline  (EXP)
(R,R)-tramadol  (EXP)
(R,R,R)-alpha-tocopherol  (EXP,ISO)
(S)-(-)-perillyl alcohol  (EXP)
(S)-AMPA  (EXP)
(S)-colchicine  (EXP,ISO)
(S)-naringenin  (EXP,ISO)
(S)-nicotine  (EXP,ISO)
(S)-ropivacaine  (ISO)
(Z)-ligustilide  (ISO)
1'-acetoxychavicol acetate  (ISO)
1,1'-azobis(N,N-dimethylformamide)  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane  (ISO)
1,1-dichloroethene  (ISO)
1,1-dimethyl-4-phenylpiperazinium iodide  (EXP)
1,2,3-Trichloropropane  (ISO)
1,2-dibromoethane  (EXP)
1,2-dichlorobenzene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (EXP,ISO)
1,3,5-trinitro-1,3,5-triazinane  (EXP)
1,3,5-trinitrobenzene  (ISO)
1,3,7,9-tetramethyluric acid  (EXP)
1,3-benzothiazole-2-thiol  (ISO)
1,3-dichloropropan-2-ol  (ISO)
1,4-benzoquinone  (ISO)
1,4-dithiothreitol  (EXP,ISO)
1,4-naphthoquinone  (ISO)
1,4-phenylenediamine  (ISO)
1,7-dimethylxanthine  (ISO)
1,8-cineole  (EXP,ISO)
1-(5-isoquinolinesulfonyl)-2-methylpiperazine  (EXP,ISO)
1-[(2,3,4-trimethoxyphenyl)methyl]piperazine  (EXP,ISO)
1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine  (ISO)
1-bromopropane  (ISO)
1-chloro-2,4,6-trinitrobenzene  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-fluoro-2,4-dinitrobenzene  (ISO)
1-hydroxy-1-norresistomycin  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP,ISO)
1-naphthaleneacetic acid  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
1-Naphthylacetylspermine  (EXP)
1-nitropyrene  (ISO)
1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine  (ISO)
1-octadec-9-enoylglycero-3-phosphate  (ISO)
1-Phenyl-6,7-dihydroxy-isochroman  (ISO)
11-deoxycorticosterone  (EXP)
11-deoxyprostaglandin E1  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (ISO)
15-acetyldeoxynivalenol  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
15-oxo-ETE  (ISO)
16,16-dimethylprostaglandin E2  (ISO)
17-hydroxyjolkinolide B  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17alpha-hydroxyprogesterone  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
1H-pyrazole  (ISO)
2''-galloylhyperin  (ISO)
2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,2'-bipyridine  (ISO)
2,2,2-trichloroethanol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,3-bis(4-hydroxyphenyl)propionitrile  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (EXP,ISO)
2,4-D  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrobenzenesulfonic acid  (ISO)
2,5-dihydroxybenzoic acid  (ISO)
2,5-hexanedione  (EXP)
2,6-di-tert-butyl-4-methylphenol  (EXP,ISO)
2,6-dichloroindophenol  (ISO)
2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile  (EXP,ISO)
2-(4-chloro-2-methylphenoxy)propanoic acid  (ISO)
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine  (EXP)
2-acetamidofluorene  (EXP)
2-acetyl-1-alkyl-sn-glycero-3-phosphocholine  (EXP,ISO)
2-amino-2-deoxy-D-galactopyranose  (EXP,ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP,ISO)
2-amino-2-deoxy-D-glucopyranose 6-phosphate  (ISO)
2-aminopurine  (ISO)
2-arachidonoylglycerol  (EXP,ISO)
2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one  (ISO)
2-chloroethanol  (ISO)
2-deoxy-D-glucose  (EXP,ISO)
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid  (ISO)
2-hydroxyethyl methacrylate  (ISO)
2-hydroxypropanoic acid  (ISO)
2-O-acetyl-1-O-octadecyl-sn-glycero-3-phosphocholine  (EXP)
2-tert-butylhydroquinone  (EXP,ISO)
2-trans,6-trans,10-trans-geranylgeranyl diphosphate  (ISO)
2-trans,6-trans-farnesyl diphosphate  (ISO)
22-Hydroxycholesterol  (ISO)
23-epi-26-deoxyactein  (ISO)
3',5'-cyclic AMP  (ISO)
3',5'-cyclic GMP  (EXP)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP)
3'-O-(4-Benzoyl)benzoyl ATP  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3,3',5'-triiodo-L-thyronine  (EXP)
3,3',5'-triiodothyronine  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP,ISO)
3,3',5-triiodo-L-thyronine  (EXP,ISO)
3,3'-diindolylmethane  (EXP,ISO)
3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol  (ISO)
3,4-dihydroxybenzoic acid  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3,5-diethoxycarbonyl-1,4-dihydrocollidine  (ISO)
3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (ISO)
3-acetyldeoxynivalenol  (ISO)
3-chloropropane-1,2-diol  (EXP,ISO)
3-hydroxybutyric acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-mercaptopropanoic acid  (ISO)
3-methyladenine  (EXP,ISO)
3-methylcatechol  (ISO)
3-methylcholanthrene  (EXP,ISO)
3-Nitrofluoranthene  (ISO)
3-nitropropanoic acid  (EXP,ISO)
3-phenylprop-2-enal  (EXP,ISO)
4'-epidoxorubicin  (ISO)
4'-hydroxydiclofenac  (EXP,ISO)
4'-Methoxychalcone  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-[6-(diaminomethylideneamino)-1-oxohexoxy]benzoic acid ethyl ester  (EXP)
4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid  (ISO)
4-\{[4-(dimethylamino)phenyl]diazenyl\}phenyl-beta-lactoside  (ISO)
4-aminobenzoic acid  (ISO)
4-hydroperoxycyclophosphamide  (ISO)
4-hydroxy-3-[4-(2-hydroxyphenyl)phenyl]-6-oxo-7H-thieno[2,3-b]pyridine-5-carbonitrile  (ISO)
4-hydroxy-TEMPO  (EXP,ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic acid methyl ester  (ISO)
4-methylcatechol  (ISO)
4-methylhistamine  (ISO)
4-nitrophenol  (ISO)
4-Nitropyrene  (ISO)
4-nitroquinoline N-oxide  (EXP)
4-nonylphenol  (EXP,ISO)
4-octylphenol  (ISO)
4-phenylbutyric acid  (ISO)
4-tert-butylphenol  (ISO)
5'-S-methyl-5'-thioadenosine  (ISO)
5,6,7-trimethoxyflavone  (ISO)
5-(2-chloroethyl)-4-methylthiazole  (ISO)
5-(2-methylpiperazine-1-sulfonyl)isoquinoline  (EXP,ISO)
5-aminoimidazole-4-carboxamide  (EXP)
5-aza-2'-deoxycytidine  (EXP,ISO)
5-azacytidine  (EXP,ISO)
5-benzyl-1-(2-hydroxyethoxymethyl)uracil  (ISO)
5-fluorouracil  (EXP,ISO)
5-Hydroxycapric acid  (EXP,ISO)
5-Isoxazoleacetic acid, 4,5-dihydro-3-(4-hydroxyphenyl)-, methyl ester  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP,ISO)
5-methoxypsoralen  (EXP)
5-Nitro-2-(3-phenylpropylamino)benzoic acid  (ISO)
6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diamine  (ISO)
6-aminonicotinamide  (ISO)
6-bromoindirubin-3'-oxime  (ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (ISO)
6-Methoxyflavone  (ISO)
6-oxoprostaglandin F1alpha  (ISO)
6-propyl-2-thiouracil  (EXP)
6alpha-methylprednisolone  (EXP,ISO)
7,12-dimethyltetraphene  (EXP,ISO)
7,8-diacetoxy-4-methylcoumarin  (ISO)
7,8-dihydroxycoumarin  (EXP,ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (EXP,ISO)
7-ketocholesterol  (ISO)
8-Br-cAMP  (EXP,ISO)
8-bromo-3',5'-cyclic GMP  (ISO)
8-OH-DPAT  (ISO)
9-cis,11-trans-octadecadienoic acid  (ISO)
9-cis-retinoic acid  (ISO)
9-Methoxycamptothecin  (ISO)
[6]-Shogaol  (ISO)
[des-Arg(9)]-bradykinin  (ISO)
AACOCF3  (ISO)
abacavir  (ISO)
abamectin  (EXP)
acarbose  (EXP,ISO)
aceclofenac  (ISO)
acetaldehyde  (EXP,ISO)
acetate  (EXP)
acetate ester  (EXP,ISO)
acetic acid  (EXP,ISO)
acetic anhydride  (ISO)
acetone  (ISO)
acetylcholine  (ISO)
acetylsalicylic acid  (EXP,ISO)
acrolein  (EXP,ISO)
acrylamide  (EXP,ISO)
acrylic acid  (EXP)
acrylonitrile  (EXP,ISO)
acteoside  (ISO)
actinomycin D  (EXP,ISO)
acyclovir  (ISO)
adenine  (EXP,ISO)
adenosine  (ISO)
Adenosine, cyclic 3',5'-[hydrogen [p(s)]-phosphorothioate]  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
Aflatoxin G1  (ISO)
agathisflavone  (EXP)
agmatine  (EXP,ISO)
agrimoniin  (ISO)
AH23848  (ISO)
AICA ribonucleotide  (EXP,ISO)
ajmalicine  (ISO)
alachlor  (ISO)
Alamandine  (EXP)
albendazole  (ISO)
albuterol  (EXP,ISO)
alcohol  (EXP,ISO)
aldehydo-D-glucosamine  (EXP,ISO)
aldehydo-D-glucosamine 6-phosphate  (ISO)
aldehydo-D-glucose  (EXP,ISO)
aldosterone  (EXP)
alendronic acid  (ISO)
alfacalcidol  (EXP)
alginic acid  (ISO)
aliskiren  (EXP)
Alisol B  (ISO)
Alkannin  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (EXP)
allantoin  (EXP,ISO)
allethrin  (ISO)
allicin  (EXP,ISO)
allopurinol  (EXP,ISO)
alloxan  (EXP,ISO)
alloxanthine  (ISO)
allyl alcohol  (EXP)
allyl isothiocyanate  (EXP,ISO)
allyl methyl disulfide  (ISO)
Aloe emodin  (ISO)
alpha-amanitin  (ISO)
Alpha-Boswellic acid  (ISO)
alpha-Chaconine  (ISO)
alpha-D-galactose  (EXP,ISO)
alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide  (ISO)
alpha-hexylcinnamaldehyde  (ISO)
alpha-linolenic acid  (EXP)
alpha-mangostin  (EXP)
alpha-methylhistamine  (ISO)
alpha-naphthoflavone  (ISO)
alpha-pinene  (EXP)
alpha-Solamarine  (ISO)
Alpinetin  (ISO)
alternariol  (ISO)
Altertoxin II  (ISO)
aluminium atom  (EXP,ISO)
aluminium hydroxide  (ISO)
aluminium oxide  (EXP,ISO)
aluminium(0)  (EXP,ISO)
alvocidib  (ISO)
AM-251  (ISO)
AM6545  (ISO)
ambroxol  (EXP)
amiloride  (EXP,ISO)
aminoguanidine  (EXP,ISO)
amiodarone  (EXP,ISO)
amitrole  (EXP,ISO)
amlexanox  (ISO)
amlodipine  (EXP)
ammonia  (EXP)
ammonium chloride  (EXP)
ammonium hexachloroplatinate  (ISO)
ammonium sulfate  (EXP)
Ammothamnine  (EXP,ISO)
amobarbital  (EXP)
amosite asbestos  (EXP,ISO)
amphetamine  (EXP,ISO)
amphibole asbestos  (EXP,ISO)
amphotericin B  (EXP)
ampicillin  (EXP,ISO)
amrinone  (ISO)
anandamide  (EXP,ISO)
andrastin A  (ISO)
andrographolide  (EXP,ISO)
androst-4-ene-3,17-dione  (ISO)
Anemoside B4  (ISO)
anethole  (EXP,ISO)
Anetholtrithion  (ISO)
angiotensin II  (ISO)
Angoline  (ISO)
aniline  (EXP)
anthocyanin  (EXP,ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
anthracene  (ISO)
anthracene-1,8,9-triol  (ISO)
antigen  (ISO)
antimony(0)  (ISO)
antimycin A  (ISO)
antipyrine  (ISO)
antirheumatic drug  (ISO)
Apafant  (ISO)
apigenin  (EXP,ISO)
apilimod  (ISO)
apocynin  (EXP,ISO)
arachidonic acid  (ISO)
arachidonyl-2'-chloroethylamide  (ISO)
Arctiin  (EXP)
aripiprazole  (ISO)
aristolochic acid A  (EXP,ISO)
aristolochic acids  (ISO)
arjunolic acid  (EXP)
Arkin (TN)  (ISO)
Aroclor 1254  (EXP)
arsane  (EXP,ISO)
arsenic acid  (ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP,ISO)
artesunate  (EXP)
asarone  (ISO)
asbestos  (EXP,ISO)
asiatic acid  (ISO)
aspalathin  (ISO)
aspartame  (ISO)
asperentin  (ISO)
asperuloside  (ISO)
Asperulosidic acid  (ISO)
astaxanthin  (ISO)
astilbin  (ISO)
astragaloside IV  (EXP,ISO)
astressin 2B  (EXP)
atorvastatin calcium  (EXP,ISO)
ATP  (EXP,ISO)
atrazine  (EXP,ISO)
atropine  (ISO)
aucubin  (ISO)
auranofin  (ISO)
aurantio-obtusin  (ISO)
aureusidin  (ISO)
azadirachtin A  (ISO)
azathioprine  (ISO)
azetidine  (ISO)
aziridines  (ISO)
azithromycin  (ISO)
azoxystrobin  (ISO)
baclofen  (ISO)
bafilomycin A1  (ISO)
baicalein  (ISO)
baicalin  (EXP,ISO)
BAPTA  (ISO)
Bardoxolone methyl  (ISO)
barium chloride  (EXP,ISO)
barium(0)  (ISO)
bathocuproine disulfonic acid  (ISO)
batimastat  (ISO)
Bavachinin  (ISO)
BAY 60-6583  (ISO)
beclomethasone  (ISO)
bellidifolin  (EXP,ISO)
Belnacasan  (EXP)
benazepril  (EXP,ISO)
benfotiamine  (ISO)
benomyl  (EXP)
bentonite  (EXP)
benzalkonium chloride  (ISO)
benzamide  (EXP,ISO)
benzbromarone  (ISO)
benzene  (EXP,ISO)
benzene-1,2,4-triol  (ISO)
benzo[a]pyrene  (EXP,ISO)
Benzo[a]pyrene-7,8-diol  (EXP)
Benzo[ghi]perylene  (ISO)
benzoic acid  (ISO)
benzylpenicillin  (ISO)
beraprost  (ISO)
berberine  (EXP,ISO)
Bergenin  (EXP,ISO)
beryllium atom  (ISO)
beryllium dihydride  (ISO)
beryllium sulfate  (ISO)
beryllium(0)  (ISO)
Besigomsin  (ISO)
beta-amyrin  (EXP,ISO)
beta-carotene  (ISO)
beta-cyclodextrin  (ISO)
beta-D-glucan  (ISO)
beta-D-glucosamine  (EXP,ISO)
beta-D-glucosamine 6-sulfate  (ISO)
beta-eudesmol  (ISO)
beta-ionone  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (EXP,ISO)
betalain  (ISO)
betulin  (ISO)
betulinic acid  (EXP)
bezafibrate  (EXP,ISO)
bicalutamide  (ISO)
bifenthrin  (EXP,ISO)
bilirubin IXalpha  (ISO)
biliverdin  (ISO)
biochanin A  (EXP,ISO)
biotin  (EXP)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisdemethoxycurcumin  (EXP)
Bisibuthiamine  (EXP)
bisoprolol  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (EXP,ISO)
Bisphenol A glycidylmethacrylate  (EXP)
bisphenol F  (EXP,ISO)
bleomycin A2  (EXP,ISO)
boldenone  (EXP)
Boldine  (ISO)
boric acid  (EXP,ISO)
boron atom  (EXP)
bortezomib  (EXP,ISO)
bosentan  (ISO)
Botulinum toxin type A  (EXP,ISO)
BQ 123  (EXP,ISO)
brefeldin A  (ISO)
Brevetoxin B  (ISO)
Brevianamide A  (ISO)
bromoacetate  (ISO)
bromocriptine  (EXP,ISO)
bromodichloromethane  (ISO)
brucine  (ISO)
bucladesine  (EXP,ISO)
budesonide  (EXP,ISO)
Budlein A  (EXP)
bufalin  (ISO)
buspirone  (EXP)
busulfan  (ISO)
butachlor  (ISO)
butanal  (ISO)
butane-2,3-dione  (ISO)
butein  (ISO)
butylated hydroxyanisole  (EXP,ISO)
Butylbenzyl phthalate  (ISO)
butyric acid  (ISO)
C.I. Natural Red 20  (ISO)
C60 fullerene  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (ISO)
caffeine  (EXP,ISO)
calcidiol  (ISO)
Calcimycin  (EXP,ISO)
calciol  (EXP,ISO)
calcitriol  (EXP,ISO)
Calcium arsenate  (EXP)
calcium atom  (ISO)
calcium dichloride  (EXP,ISO)
Calcium propionate  (EXP)
calcium(0)  (ISO)
calycosin  (EXP)
camostat  (EXP,ISO)
candesartan  (EXP,ISO)
cannabidiol  (EXP,ISO)
Cannabidivarin  (ISO)
cannabigerol  (EXP)
capsaicin  (EXP,ISO)
capsazepine  (EXP,ISO)
captan  (ISO)
captopril  (EXP,ISO)
carbachol  (EXP,ISO)
carbamate ester  (ISO)
carbamazepine  (EXP,ISO)
Carbaprostacyclin  (ISO)
carbendazim  (EXP)
CARBENOXOLONE  (ISO)
carbidopa  (ISO)
carbon atom  (ISO)
carbon monoxide  (EXP,ISO)
carbon nanotube  (EXP,ISO)
carboplatin  (EXP)
Cardamonin  (EXP,ISO)
carfilzomib  (ISO)
carmustine  (EXP,ISO)
carnosic acid  (ISO)
carnosine  (EXP,ISO)
Carnosol  (ISO)
carrageenan  (EXP,ISO)
carteolol  (ISO)
carvacrol  (EXP,ISO)
carvedilol  (EXP,ISO)
carveol  (ISO)
Casuarictin  (ISO)
catalpol  (ISO)
catechol  (ISO)
CCCP  (EXP,ISO)
cefoxitin  (ISO)
ceftaroline  (ISO)
ceftriaxone  (EXP)
celastrol  (EXP,ISO)
celecoxib  (EXP,ISO)
Cellulose, microcrystalline  (ISO)
ceric oxide  (EXP,ISO)
cerium trichloride  (ISO)
cerivastatin  (ISO)
ceruletide  (EXP,ISO)
cetylpyridinium  (ISO)
CGS-21680  (ISO)
chaetoglobosin A  (ISO)
chaetomugilin D  (ISO)
chalcone  (ISO)
chalcones  (EXP,ISO)
charcoal  (EXP)
Chebulagic acid  (EXP)
chelerythrine  (ISO)
chetomin  (ISO)
chitosan  (ISO)
chlorendic acid  (ISO)
chlornitrofen  (EXP)
chlorobenzene  (ISO)
chloroethene  (ISO)
chlorogenic acid  (EXP,ISO)
chloroprene  (EXP)
chloroquine  (EXP,ISO)
chlorothalonil  (ISO)
chlorpromazine  (ISO)
chlorpyrifos  (EXP,ISO)
cholate  (EXP)
cholesterol  (EXP,ISO)
cholic acid  (ISO)
choline  (EXP,ISO)
chondroitin sulfate  (EXP,ISO)
chromium atom  (EXP,ISO)
chromium(3+) trichloride  (ISO)
chromium(6+)  (EXP,ISO)
chrysene  (ISO)
chrysin  (EXP,ISO)
cicaprost  (ISO)
cilostazol  (EXP,ISO)
cimetidine  (ISO)
Cinobufagin  (ISO)
ciprofibrate  (ISO)
ciprofloxacin  (EXP,ISO)
cirsilineol  (ISO)
Cirsimarin  (ISO)
cis-caffeic acid  (EXP,ISO)
cisplatin  (EXP,ISO)
citronellol  (EXP)
cladribine  (ISO)
clarithromycin  (EXP,ISO)
clenbuterol  (EXP)
clobetasol  (ISO)
clodronic acid  (EXP,ISO)
clofibrate  (EXP,ISO)
clomipramine  (ISO)
clonidine  (EXP)
clonidine (amino form)  (EXP)
clonidine (imino form)  (EXP)
clopidogrel  (ISO)
clorgyline  (ISO)
cloricromen  (EXP)
clothianidin  (ISO)
cloxacillin  (ISO)
clozapine  (EXP,ISO)
cobalt atom  (EXP,ISO)
cobalt dichloride  (EXP,ISO)
cocaine  (EXP,ISO)
coenzyme Q10  (EXP,ISO)
colforsin daropate hydrochloride  (EXP,ISO)
colistin  (EXP,ISO)
compound 48/80  (ISO)
coniferyl aldehyde  (ISO)
conjugated linoleic acid  (ISO)
copanlisib  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (EXP,ISO)
copper(II) sulfate  (EXP)
cordycepin  (EXP,ISO)
corilagin  (EXP,ISO)
corticosterone  (EXP,ISO)
cortisol  (ISO)
cortisone  (ISO)
corynoline  (ISO)
costunolide  (ISO)
coumarin  (EXP,ISO)
coumarins  (ISO)
coumermycin A1  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (EXP,ISO)
crocin-1  (EXP,ISO)
crotonaldehyde  (EXP,ISO)
Cryptotanshinone  (ISO)
CU-O LINKAGE  (ISO)
cucurbitacin B  (ISO)
cudratricusxanthone A  (ISO)
cumene hydroperoxide  (ISO)
Cuprizon  (ISO)
curcumin  (EXP,ISO)
Curcumol  (ISO)
cyanidin cation  (ISO)
cyanocob(III)alamin  (EXP,ISO)
cyclizine  (ISO)
cycloastragenol  (EXP)
cycloheximide  (EXP,ISO)
cyclophosphamide  (EXP,ISO)
cyclosporin A  (EXP,ISO)
cyfluthrin  (EXP,ISO)
cyhalothrin  (EXP)
cylindrospermopsin  (ISO)
cypermethrin  (EXP,ISO)
cytarabine  (ISO)
cytisine  (ISO)
cytochalasin D  (ISO)
D-glucose  (EXP,ISO)
D-mannitol  (ISO)
D-penicillamine  (ISO)
dabigatran  (EXP)
dabrafenib  (ISO)
dacarbazine  (ISO)
daidzein  (ISO)
danazol  (EXP,ISO)
dantrolene  (EXP,ISO)
dapagliflozin  (EXP)
dapoxetine  (EXP)
DAPT  (EXP,ISO)
daunorubicin  (EXP)
DDE  (EXP,ISO)
DDT  (ISO)
decabromodiphenyl ether  (EXP,ISO)
Decursin  (ISO)
deferiprone  (ISO)
deguelin  (ISO)
dehydrocostus lactone  (ISO)
dehydroepiandrosterone  (EXP,ISO)
delphinidin  (ISO)
Delta(9)-tetrahydrocannabinolic acid  (ISO)
delta-tocotrienol  (ISO)
delta8-THC  (ISO)
demeclocycline  (ISO)
demethoxycurcumin  (EXP)
deoxycholic acid  (ISO)
Deoxycorticosterone acetate  (ISO)
deoxynivalenol  (EXP,ISO)
desferrioxamine B  (EXP,ISO)
desflurane  (ISO)
desipramine  (ISO)
devazepide  (ISO)
dexamethasone  (EXP,ISO)
dexamethasone phosphate  (EXP,ISO)
dexmedetomidine  (EXP,ISO)
dextran sulfate  (EXP,ISO)
dextromethorphan  (ISO)
Di-n-hexyl phthalate  (ISO)
Di-n-octyl phthalate  (ISO)
diallyl disulfide  (EXP,ISO)
Diallyl sulfide  (EXP,ISO)
diallyl trisulfide  (EXP,ISO)
diarsenic trioxide  (EXP,ISO)
diazinon  (EXP,ISO)
diazoxide  (EXP,ISO)
diazoxon  (ISO)
dibenziodolium  (EXP,ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dibutylstannane  (ISO)
dichlorine  (ISO)
dichloroacetic acid  (ISO)
dichloroacetyl chloride  (ISO)
dichloromethane  (ISO)
dichlorvos  (EXP)
dichromic acid  (ISO)
dichromium trioxide  (ISO)
diclofenac  (EXP,ISO)
dicoumarol  (ISO)
Didecyldimethylammonium  (ISO)
dieckol  (ISO)
dieldrin  (EXP,ISO)
dienogest  (ISO)
diethyl dithiophosphate  (ISO)
diethyl maleate  (EXP,ISO)
diethyl phthalate  (EXP,ISO)
diethyldithiocarbamic acid  (ISO)
diethylstilbestrol  (ISO)
diflunisal  (EXP)
dihydroartemisinin  (EXP)
Dihydrotanshinone I  (ISO)
dihydroxyacetone  (ISO)
diiodine  (ISO)
Diisodecyl phthalate  (ISO)
diisononyl phthalate  (ISO)
diisopropyl fluorophosphate  (EXP,ISO)
Dimaprit  (ISO)
dimemorfan  (ISO)
dimethoate  (ISO)
dimethyl fumarate  (ISO)
dimethyl sulfoxide  (EXP,ISO)
dimethylarsinic acid  (EXP,ISO)
dimethylarsinous acid  (ISO)
diminazene diaceturate  (EXP,ISO)
Diosbulbin B  (ISO)
dioscin  (EXP,ISO)
diosgenin  (EXP,ISO)
diosmetin  (ISO)
diosmin  (EXP)
dioxygen  (EXP,ISO)
diprotium oxide  (EXP,ISO)
dipyridamole  (ISO)
diquat  (EXP)
disodium cromoglycate  (ISO)
disodium selenite  (EXP,ISO)
disulfiram  (EXP,ISO)
dithianon  (ISO)
diuron  (ISO)
divanadium pentaoxide  (ISO)
dobutamine  (EXP)
docebenone  (ISO)
dodecane  (EXP)
donepezil hydrochloride  (EXP,ISO)
dopamine  (EXP,ISO)
dopaminechrome (enol form)  (EXP)
doramapimod  (ISO)
dorsomorphin  (EXP,ISO)
doxepin  (EXP)
doxifluridine  (ISO)
doxorubicin  (EXP,ISO)
doxycycline  (ISO)
dydrogesterone  (ISO)
ebselen  (EXP)
EC 3.1.1.4 (phospholipase A2) inhibitor  (ISO)
edaravone  (EXP,ISO)
efavirenz  (EXP)
elemental boron  (EXP)
elemental carbon  (ISO)
elemental selenium  (EXP,ISO)
ellagic acid  (EXP,ISO)
emamectin benzoate  (ISO)
embelin  (EXP,ISO)
emodin  (EXP,ISO)
enalapril  (EXP,ISO)
enalaprilat dihydrate  (ISO)
endosulfan  (EXP,ISO)
enflurane  (EXP)
enilconazole  (ISO)
Enterolactone  (ISO)
epalrestat  (ISO)
Epimedin B  (ISO)
eplerenone  (EXP)
erdosteine  (EXP,ISO)
ergothioneine  (EXP)
eriodictyol  (ISO)
erythromycin A  (ISO)
erythrosin B  (EXP)
esculetin  (ISO)
estragole  (ISO)
estriol  (EXP,ISO)
estrone  (ISO)
etacrynic acid  (ISO)
ethanol  (EXP,ISO)
ethidium  (ISO)
ethion  (ISO)
ethionamide  (EXP)
Ethyl icosapentate  (EXP)
ethyl methanesulfonate  (ISO)
Ethyl pyruvate  (ISO)
ethylene glycol  (EXP)
ethylene glycol bis(2-aminoethyl)tetraacetic acid  (ISO)
ethylenediaminetetraacetic acid  (ISO)
ethylmalonic acid  (EXP)
ethylmercuric chloride  (ISO)
eticlopride(1+)  (EXP)
etidronic acid  (ISO)
etoposide  (EXP,ISO)
eugenol  (EXP,ISO)
eumelanin  (ISO)
eupatilin  (ISO)
everolimus  (ISO)
Evodiamine  (ISO)
excitatory amino acid agonist  (EXP)
ezetimibe  (EXP)
famotidine  (EXP,ISO)
Fargesin  (ISO)
farnesol  (EXP,ISO)
farnesyl diphosphate  (ISO)
farrerol  (EXP)
fasudil  (EXP,ISO)
febuxostat  (EXP,ISO)
felodipine  (ISO)
fenamic acid  (ISO)
fenbendazole  (ISO)
fenitrothion  (EXP)
fenofibrate  (EXP,ISO)
fenoprofen  (ISO)
fenpropathrin  (EXP)
fentin chloride  (ISO)
fentin hydroxide  (ISO)
fenvalerate  (EXP)
ferric ammonium citrate  (ISO)
ferric oxide  (ISO)
ferroheme b  (ISO)
ferrosoferric oxide  (EXP)
ferrostatin-1  (ISO)
ferruginol  (EXP)
Fexaramine  (ISO)
Fexofenadine hydrochloride  (ISO)
Fidarestat  (ISO)
finasteride  (EXP)
fingolimod hydrochloride  (ISO)
fipronil  (EXP)
fisetin  (EXP,ISO)
Flavokawain A  (ISO)
flavokawain B  (ISO)
flavones  (ISO)
flavonoids  (EXP,ISO)
flavonols  (ISO)
flucloxacillin  (ISO)
flufenamic acid  (EXP,ISO)
flumequine  (ISO)
flunisolide  (ISO)
fluoranthene  (EXP,ISO)
fluorene  (ISO)
fluorometholone  (ISO)
fluoxetine  (EXP,ISO)
flurbiprofen  (ISO)
flutamide  (EXP,ISO)
fluticasone  (ISO)
folic acid  (EXP,ISO)
fomepizole  (EXP)
formaldehyde  (EXP,ISO)
formic acid  (ISO)
formoterol fumarate  (EXP,ISO)
Forsythiaside  (ISO)
fosinopril  (ISO)
fragrance  (ISO)
fraxetin  (ISO)
Fraxinellone  (ISO)
fructosamine  (ISO)
fructose  (EXP,ISO)
fucoxanthin  (ISO)
fulvestrant  (EXP,ISO)
fumaric acid  (ISO)
fumigaclavine C  (ISO)
fumonisin B1  (ISO)
furan  (EXP,ISO)
furosemide  (EXP,ISO)
Fusarenone X  (ISO)
gabexate methanesulfonate  (EXP)
gadolinium trichloride  (EXP,ISO)
galactose  (EXP,ISO)
galangin  (EXP,ISO)
galanthamine  (EXP)
gallic acid  (EXP,ISO)
gallocatechin  (ISO)
gamma-aminobutyric acid  (EXP)
gamma-hexachlorocyclohexane  (EXP,ISO)
gamma-linolenic acid  (ISO)
gamma-tocopherol  (EXP,ISO)
ganciclovir  (ISO)
Ganoderic acid A  (ISO)
Ganoderic acid C2  (ISO)
Garcinol  (ISO)
Gastrodin  (EXP,ISO)
gefitinib  (ISO)
geldanamycin  (ISO)
gemcitabine  (ISO)
gemfibrozil  (EXP,ISO)
Genipin  (ISO)
Geniposide  (ISO)
genistein  (EXP,ISO)
genkwanin  (ISO)
gentamycin  (EXP,ISO)
Gentiopicrin  (ISO)
Geraniin  (ISO)
geraniol  (EXP,ISO)
geranylgeraniol  (ISO)
ghrelin  (ISO)
Gingerenone A  (ISO)
gingerol  (EXP,ISO)
Ginkgolide A  (ISO)
ginkgolide B  (ISO)
Ginkgolide C  (EXP)
ginsenoside C-K  (ISO)
ginsenoside Rb1  (ISO)
ginsenoside Re  (EXP,ISO)
ginsenoside Rg1  (EXP,ISO)
glafenine  (EXP)
gliclazide  (EXP)
gliotoxin  (ISO)
glucagon  (ISO)
glucose  (EXP,ISO)
glutaraldehyde  (ISO)
glutathione  (EXP,ISO)
Glutathione ethyl ester  (ISO)
glutinol  (ISO)
Gly-His-Lys  (ISO)
glyburide  (EXP,ISO)
glycerol  (EXP)
glycidol  (EXP)
glycine  (ISO)
glycine betaine  (EXP,ISO)
glycyrrhetinate  (EXP,ISO)
glycyrrhetinic acid  (EXP,ISO)
glycyrrhizinic acid  (EXP,ISO)
glyoxal  (EXP)
glyphosate  (EXP,ISO)
Goe 6976  (ISO)
gold atom  (ISO)
gold nanoparticle  (EXP)
gold(0)  (ISO)
gossypin  (EXP)
graphene oxide  (ISO)
graphite  (EXP,ISO)
griseofulvin  (ISO)
GSK690693  (ISO)
guanidines  (ISO)
guggulsterone  (EXP,ISO)
GW 1929  (ISO)
GW 4064  (ISO)
GW 501516  (ISO)
GW 6471  (EXP,ISO)
gypenoside LXXV  (ISO)
haloperidol  (EXP,ISO)
halothane  (EXP,ISO)
Harpagide  (ISO)
helenalin  (ISO)
heme b  (ISO)
hemin  (EXP,ISO)
heparin  (ISO)
herbacetin  (EXP)
herbicide  (EXP,ISO)
herbimycin  (ISO)
heroin  (ISO)
hesperetin  (EXP,ISO)
hesperidin  (EXP,ISO)
hexadecanoic acid  (EXP,ISO)
hexaflumuron  (EXP)
hexanal  (ISO)
high-density lipoprotein cholesterol  (EXP,ISO)
hinokiflavone  (ISO)
hispidulin  (ISO)
histamine  (EXP,ISO)
homocysteine  (EXP,ISO)
homoeriodictyol  (ISO)
Honokiol  (EXP,ISO)
HU-308  (EXP,ISO)
huperzine A  (EXP)
hyaluronic acid  (EXP,ISO)
hydralazine  (EXP,ISO)
hydrocortisone succinate  (ISO)
hydrogen chloride  (EXP,ISO)
hydrogen peroxide  (EXP,ISO)
hydrogen sulfide  (ISO)
hydroquinone  (EXP,ISO)
hydroquinone O-beta-D-glucopyranoside  (EXP)
hydroxamic acid  (EXP,ISO)
hydroxychloroquine  (ISO)
hydroxycitronellal  (ISO)
hydroxysafflor yellow A  (EXP,ISO)
hydroxytyrosol  (EXP,ISO)
hydroxyurea  (ISO)
hypoxanthine  (ISO)
ibrutinib  (ISO)
Ibudilast  (EXP)
ibuprofen  (EXP,ISO)
icariin  (EXP,ISO)
icatibant  (EXP)
ICI 118551  (EXP,ISO)
icosanoid  (EXP)
idelalisib  (ISO)
ifosfamide  (EXP)
Iguratimod  (EXP)
Ile(5)-angiotensin II  (ISO)
imidacloprid  (EXP,ISO)
Imipenem-cilastatin  (ISO)
imipramine  (EXP,ISO)
imiquimod  (ISO)
immunological adjuvant  (EXP)
IMP  (EXP)
indinavir  (ISO)
indirubin-3'-monoxime  (ISO)
indole-3-acetic acid  (ISO)
indole-3-methanol  (EXP,ISO)
indoline  (EXP)
indometacin  (EXP,ISO)
indoprofen  (ISO)
insulin  (EXP)
insulin (human)  (EXP)
iohexol  (EXP,ISO)
ionomycin  (EXP,ISO)
iprodione  (ISO)
irbesartan  (EXP,ISO)
irigenin  (ISO)
irinotecan  (EXP,ISO)
iron atom  (EXP,ISO)
iron dextran  (EXP,ISO)
iron trichloride  (ISO)
iron(0)  (EXP,ISO)
iron(2+) sulfate (anhydrous)  (EXP,ISO)
iron(III) citrate  (ISO)
iron(III) nitrilotriacetate  (EXP,ISO)
isatin  (EXP)
isoamylol  (ISO)
isocyanates  (ISO)
isoeugenol  (ISO)
isoflavones  (ISO)
isoflurane  (EXP,ISO)
isoliquiritigenin  (EXP,ISO)
isoniazide  (EXP,ISO)
isoorientin  (EXP)
isoprenaline  (EXP,ISO)
isorhamnetin  (EXP,ISO)
isoscutellarein  (ISO)
isothiocyanate  (ISO)
isotretinoin  (EXP,ISO)
isovitexin  (EXP,ISO)
itraconazole  (ISO)
ivermectin  (ISO)
jaspamide  (ISO)
JTE-013  (ISO)
juglone  (ISO)
kaempferol  (EXP,ISO)
kaempferol 3-O-beta-D-glucoside  (ISO)
kahweol  (ISO)
kainic acid  (EXP,ISO)
kenpaullone  (EXP)
ketamine  (EXP,IEP,ISO)
ketoconazole  (EXP,ISO)
ketoprofen  (ISO)
ketotifen  (EXP,ISO)
KN-93  (ISO)
kojic acid  (EXP)
KT 5720  (ISO)
KT 5823  (ISO)
Kukoamine B  (ISO)
kuwanone G  (ISO)
kynurenic acid  (ISO)
L-1,4-dithiothreitol  (EXP,ISO)
L-365260  (ISO)
L-arginine  (EXP,ISO)
L-ascorbic acid  (EXP,ISO)
L-cysteine  (EXP)
L-ethionine  (ISO)
L-gamma-glutamyl-L-cysteine  (ISO)
L-glutamic acid  (ISO)
L-methionine  (EXP,ISO)
L-mimosine  (EXP,ISO)
L-proline betaine  (ISO)
lactacystin  (ISO)
lactucin  (ISO)
lactulose  (EXP,ISO)
lamivudine  (EXP)
lansoprazole  (EXP,ISO)
latrunculin B  (ISO)
lead diacetate  (EXP,ISO)
lead nitrate  (EXP,ISO)
lead(0)  (EXP,ISO)
lead(II) chloride  (EXP,ISO)
leflunomide  (ISO)
lenalidomide  (EXP,ISO)
lentinan  (ISO)
Leonurine  (EXP,ISO)
letrozole  (EXP)
leukotriene D4  (ISO)
leuprolide  (EXP)
levamisole  (ISO)
levetiracetam  (EXP)
levocabastine  (ISO)
levofloxacin  (ISO)
levonorgestrel  (ISO)
Licarin A  (EXP)
Licochalcone A  (ISO)
Licochalcone B  (ISO)
lidocaine  (ISO)
Liensinine  (ISO)
lignan  (ISO)
lignin  (ISO)
limonene  (EXP,ISO)
limonin  (ISO)
linagliptin  (EXP,ISO)
linalool  (EXP,ISO)
linalyl acetate  (ISO)
linoleic acid  (EXP,ISO)
linsidomine  (ISO)
linuron  (ISO)
lipid As  (ISO)
lipoic acid  (EXP,ISO)
lipophosphoglycan  (ISO)
lipopolysaccharide  (EXP,ISO)
lipoteichoic acid  (EXP,ISO)
lipoxin A4  (EXP,ISO)
liquiritin  (ISO)
liraglutide  (EXP)
lithium atom  (EXP,ISO)
lithium carbonate  (ISO)
lithium chloride  (EXP,ISO)
lithium hydride  (EXP,ISO)
lithocholic acid  (ISO)
lixisenatide  (ISO)
LLY-507  (ISO)
loganin  (EXP,ISO)
lonafarnib  (ISO)
lopinavir  (ISO)
lorcaserin  (ISO)
losartan  (EXP,ISO)
lovastatin  (EXP,ISO)
Lucidone  (ISO)
lumiracoxib  (ISO)
lupeol  (EXP,ISO)
luteolin  (EXP,ISO)
Luteolin 7-methyl ether  (EXP)
luteolin 7-O-beta-D-glucoside  (ISO)
luzindole  (ISO)
LY294002  (EXP,ISO)
lycopene  (EXP,ISO)
lycorine  (ISO)
m-xylene  (EXP)
Macrosphelide B  (ISO)
madecassoside  (ISO)
magnesium atom  (EXP)
Magnolol  (ISO)
malathion  (EXP,ISO)
maleic acid  (ISO)
malonaldehyde  (ISO)
malvidin  (ISO)
malvidin 3-O-beta-D-glucoside  (ISO)
mancozeb  (ISO)
maneb  (EXP,ISO)
manganese atom  (EXP,ISO)
manganese(0)  (EXP,ISO)
manganese(II) chloride  (EXP,ISO)
manganese(II) sulfate  (ISO)
mangiferin  (EXP,ISO)
manoalide  (ISO)
manumycin A  (ISO)
masitinib  (ISO)
masoprocol  (ISO)
MC1568  (ISO)
mebendazole  (ISO)
Mecamylamine  (EXP)
mechlorethamine  (EXP,ISO)
meclofenamic acid  (ISO)
mecoprop  (ISO)
medroxyprogesterone acetate  (ISO)
MeIQx  (ISO)
melatonin  (EXP,ISO)
melittin  (EXP,ISO)
meloxicam  (ISO)
melphalan  (ISO)
memantine  (EXP,ISO)
menadione  (EXP,ISO)
mephedrone  (EXP)
mercaptoethanol  (ISO)
mercury atom  (EXP,ISO)
mercury dichloride  (EXP,ISO)
mercury(0)  (EXP,ISO)
mesalamine  (EXP,ISO)
metam  (ISO)
metamizole sodium  (EXP)
metformin  (EXP,ISO)
methacholine chloride  (ISO)
methadone  (EXP)
methamphetamine  (EXP,ISO)
methanol  (ISO)
methimazole  (EXP)
methotrexate  (EXP,ISO)
methoxsalen  (ISO)
methoxychlor  (ISO)
methyl 3,4,5-trihydroxybenzoate  (ISO)
methyl beta-cyclodextrin  (ISO)
methyl L-leucinate  (EXP)
methyl methacrylate  (ISO)
Methyl palmitate  (ISO)
methyl salicylate  (ISO)
methylene blue  (EXP)
methylglyoxal  (EXP,ISO)
methylisothiazolinone  (ISO)
methyllycaconitine  (EXP,ISO)
methylmalonic acid  (EXP)
methylmercury chloride  (EXP,ISO)
methylphenidate  (ISO)
Methylthiouracil  (ISO)
Methysticin  (ISO)
metiram  (ISO)
metoclopramide  (ISO)
metoprolol  (EXP)
metronidazole  (ISO)
metyrapone  (EXP,ISO)
mevalonic acid  (EXP,ISO)
mevastatin  (ISO)
mexiletine  (ISO)
microcystin-LR  (EXP,ISO)
mifepristone  (EXP,ISO)
Miglitol  (EXP,ISO)
milrinone  (ISO)
minocycline  (EXP,ISO)
miquelianin  (EXP,ISO)
mirtazapine  (EXP)
misoprostol  (ISO)
mitogen  (EXP)
MK 571  (ISO)
MK-2206  (EXP,ISO)
mocetinostat  (ISO)
molybdenum trichloride  (ISO)
mometasone furoate  (ISO)
monascin  (EXP,ISO)
mono(2-ethylhexyl) phthalate  (ISO)
mono(5-carboxy-2-ethylpentyl) phthalate  (ISO)
monobenzyl phthalate  (ISO)
Monobutylphthalate  (ISO)
monocrotaline  (EXP,ISO)
monocrotophos  (EXP)
monosodium L-glutamate  (EXP,ISO)
monotropein  (ISO)
montelukast  (EXP,ISO)
morin  (EXP,ISO)
morphine  (EXP,ISO)
Morroniside  (EXP,ISO)
moxifloxacin  (ISO)
muramyl dipeptide  (ISO)
mycophenolic acid  (EXP,ISO)
mycotoxin  (ISO)
Mycotrienin I  (ISO)
Mycotrienin II  (ISO)
myo-inositol hexakisphosphate  (ISO)
myricetin  (EXP,ISO)
myricitrin  (ISO)
myrtenol  (EXP)
Myrtucommulone A  (ISO)
myxothiazol  (ISO)
N(gamma)-nitro-L-arginine methyl ester  (EXP,ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N,N-dimethylacetamide  (ISO)
N,N-dimethylformamide  (ISO)
N,O-dimethyltyramine  (ISO)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (EXP,ISO)
N-[2-(diethylamino)ethyl]-2-methoxy-5-methylsulfonylbenzamide  (EXP)
N-[3,5-bis(trifluoromethyl)phenyl]-5-chloro-2-hydroxybenzamide  (EXP,ISO)
N-[3-(aminomethyl)benzyl]acetamidine  (ISO)
N-acetyl-beta-D-glucosamine  (ISO)
N-acetyl-D-glucosamine  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP,ISO)
N-butyl-N-(4-hydroxybutyl)nitrosamine  (EXP)
N-desethylamiodarone  (ISO)
N-ethyl-5'-carboxamidoadenosine  (ISO)
N-ethyl-N-nitrosourea  (ISO)
N-ethylmaleimide  (ISO)
N-formyl-L-methionyl-L-leucyl-L-phenylalanine  (ISO)
N-hexadecanoylsphingosine  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP,ISO)
N-methyl-N-nitrosourea  (EXP,ISO)
N-methylnicotinate  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP,ISO)
N-tosyl-L-phenylalanyl chloromethyl ketone  (ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (EXP,ISO)
nafcillin  (ISO)
naloxone  (EXP,ISO)
naltrexone  (EXP)
nandrolone  (ISO)
Nandrolone decanoate  (EXP)
naphthalene  (ISO)
naproxen  (EXP,ISO)
Narciclasine  (ISO)
naringin  (EXP,ISO)
nefazodone  (EXP,ISO)
Neferine  (EXP)
nelfinavir  (ISO)
neoastilbin  (ISO)
neocuproine  (ISO)
neoechinulin A  (ISO)
Neoisoliquiritin  (ISO)
neomycin  (ISO)
neosaxitoxin  (ISO)
neostigmine  (EXP)
nerolidol  (EXP)
nickel atom  (EXP,ISO)
nickel dichloride  (EXP,ISO)
nickel sulfate  (ISO)
niclosamide  (ISO)
nicorandil  (EXP,ISO)
nicotinamide  (EXP,ISO)
nicotine  (EXP,ISO)
nicotinic acid  (EXP,ISO)
nifedipine  (EXP)
nifuroxazide  (EXP,ISO)
nigericin  (ISO)
nilotinib  (EXP,ISO)
nimesulide  (EXP,ISO)
nimodipine  (ISO)
nitrates  (ISO)
nitric oxide  (EXP,ISO)
nitrites  (EXP,ISO)
nitrofen  (EXP,ISO)
nitroflurbiprofen  (EXP,ISO)
nitrofurazone  (EXP)
nitrogen dioxide  (EXP,ISO)
nitroglycerin  (EXP,ISO)
nitroprusside  (EXP,ISO)
nitrososulfamethoxazole  (ISO)
NMN zwitterion  (ISO)
nobiletin  (EXP)
nocodazole  (ISO)
Nodularin  (EXP,ISO)
nonane  (EXP)
nonanoic acid  (ISO)
nonivamide  (ISO)
Nonylphenol  (EXP,ISO)
norlaudanosoline  (ISO)
nortriptyline  (ISO)
norwogonin  (ISO)
notoginsenoside R1  (EXP,ISO)
NS-398  (EXP,ISO)
NSC 23766  (ISO)
o-anisidine  (ISO)
obeticholic acid  (EXP,ISO)
ochratoxin A  (EXP,ISO)
octadecanoic acid  (ISO)
octan-1-ol  (ISO)
octreotide  (EXP,ISO)
okadaic acid  (ISO)
olanzapine  (ISO)
olaparib  (ISO)
oleanolic acid  (ISO)
oleic acid  (EXP,ISO)
oleuropein  (ISO)
oligopeptide  (ISO)
Olmesartan medoxomil  (EXP)
Olopatadine hydrochloride  (ISO)
omeprazole  (EXP,ISO)
omethoate  (EXP)
Ondansetron  (EXP)
Ono-AE1-329  (ISO)
organoselenium compound  (EXP,ISO)
oridonin  (EXP)
orlistat  (EXP,ISO)
oroxylin A  (EXP,ISO)
oxaliplatin  (EXP)
oxidopamine  (EXP,ISO)
oxybutynin  (ISO)
ozone  (EXP,ISO)
p-cresol  (ISO)
p-menth-4(8)-en-3-one  (EXP)
p-menthan-3-ol  (ISO)
p-tolualdehyde  (ISO)
paclitaxel  (EXP,ISO)
paeoniflorin  (EXP,ISO)
Paeonol  (EXP,ISO)
palmatine  (EXP,ISO)
Palmitic acid(d3)  (ISO)
palmitoyl ethanolamide  (ISO)
pamidronate  (ISO)
paracetamol  (EXP,ISO)
paraoxon  (ISO)
paraquat  (EXP,ISO)
parathion  (ISO)
parathion-methyl  (EXP,ISO)
paricalcitol  (EXP,ISO)
paroxetine  (ISO)
parthenolide  (EXP,ISO)
patchouli alcohol  (EXP,ISO)
paxilline  (ISO)
PCB138  (ISO)
pefloxacin  (ISO)
pelargonidin  (ISO)
penconazole  (ISO)
pendimethalin  (EXP)
pentachlorophenol  (ISO)
pentanal  (ISO)
pentetic acid  (ISO)
pentobarbital  (EXP,ISO)
Pentoxifylline  (EXP,ISO)
peptidoglycan  (EXP,ISO)
perfluorobutyric acid  (ISO)
perfluorodecanoic acid  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
perifosine  (ISO)
perillyl alcohol  (EXP)
perindopril  (EXP,ISO)
permethrin  (EXP,ISO)
peroxynitrous acid  (EXP)
pevonedistat  (ISO)
pexidartinib  (ISO)
phenanthrene  (EXP,ISO)
phenanthridone  (EXP,ISO)
phencyclidine  (EXP)
phenethyl caffeate  (EXP,ISO)
phenethyl isothiocyanate  (EXP,ISO)
phenobarbital  (EXP,ISO)
phenol  (ISO)
phentolamine  (EXP)
phenylacetaldehyde  (ISO)
phenylarsine oxide  (ISO)
phenylbutazone  (ISO)
phenylephrine  (EXP)
phenylhydrazine  (ISO)
phenytoin  (ISO)
PhIP  (ISO)
phloretin  (EXP,ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phosalone  (EXP)
phosgene  (EXP)
phosmet  (ISO)
phosphatidic acid  (ISO)
phosphatidylcholine  (ISO)
phosphocholine  (ISO)
phosphorylcholine chloride  (ISO)
phoxim  (EXP)
phthalaldehyde  (ISO)
phthalazine  (EXP)
phthalic anhydride  (ISO)
phthalimide  (ISO)
physostigmine  (ISO)
phytoestrogen  (ISO)
Phytolaccoside E  (ISO)
phytosterols  (ISO)
piclamilast  (EXP)
picolinic acid  (EXP)
picropodophyllotoxin  (ISO)
pifithrin-?  (EXP)
pimecrolimus  (ISO)
pimobendan  (ISO)
Pinacidil  (EXP,ISO)
pinitol  (EXP,ISO)
pinostrobin  (EXP)
pioglitazone  (EXP,ISO)
Pioglitazone hydrochloride  (EXP)
piperacillin  (EXP)
piperine  (ISO)
Pipermethystine  (EXP)
pipoxolan  (ISO)
Pirarubicin  (EXP)
pirfenidone  (EXP,ISO)
pirinixic acid  (EXP,ISO)
piroxicam  (ISO)
pitavastatin  (ISO)
pitavastatin(1-)  (ISO)
platycodin D  (EXP,ISO)
plaunotol  (ISO)
pluronic P-123  (ISO)
PNU-282987  (ISO)
Poloxamer  (ISO)
Polpunonic acid  (ISO)
poly(ethylene)  (ISO)
poly(I:C)  (EXP,ISO)
poly(vinyl chloride)  (ISO)
polymyxin B2  (EXP,ISO)
polyphosphates  (ISO)
Potassium 2,6-dihydroxytriazinecarboxylate  (EXP,ISO)
potassium atom  (EXP,ISO)
potassium bromate  (ISO)
potassium chloride  (EXP)
potassium chromate  (ISO)
potassium dichromate  (EXP,ISO)
PR-39  (ISO)
Praeruptorin A  (ISO)
pravastatin  (ISO)
prednisolone  (EXP,ISO)
prednisone  (ISO)
pregabalin  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
PRIM-O-GLUCOSYLCIMIFUGIN  (EXP,ISO)
pristane  (EXP)
proanthocyanidin  (EXP)
probenecid  (EXP,ISO)
probucol  (EXP,ISO)
procaterol  (ISO)
procyanidin B1  (ISO)
procyanidin B2  (EXP)
procymidone  (ISO)
prodigiosin  (EXP)
progesterone  (EXP,ISO)
promethazine  (EXP)
propacetamol  (ISO)
propamocarb  (ISO)
propan-2-ol  (ISO)
propanil  (ISO)
propiconazole  (ISO)
propionic acid  (EXP)
propofol  (ISO)
propranolol  (EXP)
propylparaben  (ISO)
prostaglandin A2  (ISO)
prostaglandin D2  (ISO)
prostaglandin E1  (EXP,ISO)
prostaglandin E2  (EXP,ISO)
prostaglandin F2alpha  (ISO)
protein kinase inhibitor  (EXP,ISO)
protoporphyrin  (ISO)
prunetin  (ISO)
Ptaquiloside  (ISO)
pterostilbene  (ISO)
puerarin  (EXP,ISO)
Punicalagin  (EXP)
purmorphamine  (EXP)
pyocyanine  (ISO)
pyrene  (ISO)
Pyridostigmine bromide  (EXP,ISO)
pyridoxamine  (EXP)
pyrrolidine dithiocarbamate  (EXP,ISO)
pyrvinium  (EXP)
quartz  (EXP,ISO)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-galactopyranoside  (ISO)
quercetin 3-O-beta-D-glucofuranoside  (EXP)
quercetin 3-O-beta-D-glucopyranoside  (EXP)
quercetin 3-sulfate  (ISO)
quercitrin  (EXP)
quinazolines  (ISO)
quinine  (ISO)
quinoline  (ISO)
quinolinic acid  (EXP)
Quinotrierixin  (ISO)
rac-1,2-dichloropropane  (ISO)
rac-lactic acid  (ISO)
raloxifene  (EXP,ISO)
ramipril  (EXP)
ranitidine  (EXP,ISO)
Ranitidine bismuth citrate  (ISO)
raspberry ketone  (EXP,ISO)
reactive oxygen species  (EXP,ISO)
rebaudioside A  (EXP)
remdesivir  (ISO)
reserpine  (EXP)
resiniferatoxin  (EXP)
resiquimod  (ISO)
resolvin D1  (ISO)
resolvin D2  (ISO)
resorcinol  (ISO)
resveratrol  (EXP,ISO)
Rhein  (ISO)
Rhynchophylline  (EXP)
ribavirin  (EXP,ISO)
riboflavin  (ISO)
riddelliine  (EXP)
rifampicin  (ISO)
rifaximin  (ISO)
Riluzole  (ISO)
rimexolone  (ISO)
rimonabant  (EXP,ISO)
ritonavir  (ISO)
rivaroxaban  (EXP)
rivastigmine  (EXP)
Ro 31-8220  (ISO)
rofecoxib  (EXP,ISO)
roflumilast  (EXP,ISO)
rolipram  (EXP,ISO)
ropinirole  (EXP)
Roridin A  (ISO)
rosmarinic acid  (EXP,ISO)
rosuvastatin calcium  (EXP)
rotenone  (EXP,ISO)
rucaparib  (ISO)
Ruscogenin  (ISO)
Rutecarpine  (ISO)
ruthenium red  (ISO)
rutin  (EXP,ISO)
ruxolitinib  (ISO)
ryanodine  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-adenosyl-L-methioninate  (EXP,ISO)
S-adenosyl-L-methionine  (EXP,ISO)
S-allylcysteine  (EXP,ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP,ISO)
S-nitrosoglutathione  (ISO)
saccharin  (ISO)
salicylates  (EXP)
salicylic acid  (EXP,ISO)
Salidroside  (EXP,ISO)
Salmeterol xinafoate  (ISO)
salubrinal  (ISO)
Salvianolic acid A  (EXP,ISO)
salvianolic acid B  (EXP,ISO)
Sanggenon C  (EXP)
sanguinarine  (ISO)
saquinavir  (ISO)
sarin  (EXP)
saroglitazar  (ISO)
sarpogrelate  (ISO)
saxagliptin  (EXP)
SB 203580  (EXP,ISO)
SB 206553  (ISO)
SB 415286  (ISO)
scalaradial  (ISO)
sciadopitysin  (ISO)
scoparone  (ISO)
scopolamine  (EXP,ISO)
scopoletin  (EXP)
scutellarin  (ISO)
selenium atom  (EXP,ISO)
semaglutide  (EXP,ISO)
serotonin  (ISO)
serpentine asbestos  (EXP,ISO)
sertraline  (ISO)
Sesamol  (EXP,ISO)
sesquiterpene  (ISO)
sevoflurane  (EXP,ISO)
Shikonin  (ISO)
sildenafil citrate  (EXP,ISO)
silibinin  (EXP,ISO)
silicic acid  (ISO)
silicon atom  (EXP)
silicon carbide  (EXP)
silicon dioxide  (EXP,ISO)
silver atom  (EXP,ISO)
silver(0)  (EXP,ISO)
silychristin  (ISO)
simazine  (ISO)
simvastatin  (EXP,ISO)
sinapic acid  (EXP,ISO)
sincalide  (EXP)
sinigrin  (ISO)
Sinomenine  (ISO)
sirolimus  (EXP,ISO)
sirtinol  (EXP,ISO)
SM-164  (ISO)
sodium acetate trihydrate  (ISO)
sodium arsenate  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium azide  (EXP)
sodium benzoate  (EXP,ISO)
sodium chloride  (EXP,ISO)
sodium cholate  (EXP)
sodium dichromate  (ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (EXP,ISO)
sodium hydrogencarbonate  (ISO)
sodium hydrogensulfite  (ISO)
sodium nitrite  (EXP,ISO)
Sodium oleate  (ISO)
sodium perchlorate  (EXP)
sodium propionate  (ISO)
Sodium salicylate  (EXP,ISO)
sodium silicate  (EXP)
sodium stibogluconate  (ISO)
solasodine  (EXP)
Solithromycin  (ISO)
Soman  (EXP,ISO)
Sophocarpine  (ISO)
Sophoricoside  (ISO)
sorafenib  (ISO)
sorbinil  (ISO)
soyasaponin I  (ISO)
sphingosine 1-phosphate  (ISO)
spironolactone  (EXP,ISO)
splitomicin  (ISO)
squalene  (ISO)
SR 144528  (ISO)
stattic  (ISO)
staurosporine  (ISO)
stavudine  (ISO)
sterigmatocystin  (ISO)
stigmasterol  (ISO)
streptomycin  (ISO)
streptozocin  (EXP,ISO)
styrene  (ISO)
succimer  (EXP,ISO)
sucrose  (ISO)
sulfamethizole  (ISO)
sulfapyridine  (EXP,ISO)
sulfasalazine  (EXP,ISO)
sulforaphane  (ISO)
sulfoxaflor  (EXP)
sulfur dioxide  (EXP,ISO)
sulindac  (EXP,ISO)
sulindac sulfide  (ISO)
sulindac sulfone  (EXP)
Sulpyrine  (EXP)
sumatriptan  (EXP)
sunitinib  (EXP)
Sunset Yellow FCF  (ISO)
superoxide  (ISO)
Suplatast tosilate  (ISO)
suramin  (ISO)
surfactin  (ISO)
surfactin C  (ISO)
synephrine  (ISO)
syringic acid  (EXP,ISO)
syringin  (ISO)
T-2 toxin  (EXP,ISO)
tacrine  (ISO)
tacrolimus hydrate  (EXP,ISO)
tadalafil  (EXP,ISO)
Talc  (ISO)
tamibarotene  (EXP,ISO)
tamoxifen  (EXP,ISO)
tangeretin  (EXP)
tannic acid  (EXP)
Tanshinone I  (ISO)
tartrazine  (EXP)
taurine  (EXP,ISO)
taurochenodeoxycholic acid  (EXP)
taurocholic acid  (EXP,ISO)
tazobactam  (EXP)
tebuconazole  (ISO)
tectorigenin  (ISO)
telithromycin  (EXP)
telmisartan  (EXP,ISO)
temozolomide  (ISO)
tenofovir disoproxil fumarate  (EXP,ISO)
tephrosin  (ISO)
terameprocol  (ISO)
terbinafine  (ISO)
terbutaline  (EXP,ISO)
Terfenadine  (ISO)
teriflunomide  (EXP,ISO)
tert-butanol  (EXP)
tert-butyl hydroperoxide  (EXP,ISO)
testosterone  (EXP,ISO)
testosterone enanthate  (EXP)
Testosterone propionate  (ISO)
tetrachloro-1,4-benzoquinone  (ISO)
Tetrachlorobisphenol A  (ISO)
tetrachloroethene  (EXP)
tetrachlorohydroquinone  (ISO)
tetrachloromethane  (EXP,ISO)
tetracyclines  (ISO)
tetradecane  (EXP)
tetrahydrocurcumin  (EXP)
tetralin  (ISO)
tetramethylpyrazine  (EXP,ISO)
Tetramethylthiourea  (EXP,ISO)
tetraphene  (ISO)
tetrathiomolybdate(2-)  (ISO)
tetrodotoxin  (ISO)
thalidomide  (EXP,ISO)
thapsigargin  (ISO)
Theaflavin 3,3'-digallate  (EXP,ISO)
theophylline  (EXP,ISO)
thiamethoxam  (EXP)
thiamine(1+) chloride  (EXP)
thiazoles  (EXP)
thiazolidinediones  (ISO)
thiazolidines  (EXP)
thimerosal  (ISO)
thioacetamide  (EXP,ISO)
thiomalic acid  (ISO)
thiopental  (ISO)
thiram  (ISO)
thromboxane B2  (ISO)
thymol  (EXP,ISO)
thymol sulfate(1-)  (EXP,ISO)
thymoquinone  (EXP)
thyroxine  (EXP,ISO)
tigecycline  (EXP,ISO)
Timosaponin b ii  (ISO)
Tiopronin  (EXP)
tiotropium bromide  (ISO)
tipifarnib  (ISO)
Tiron  (EXP)
titanium atom  (EXP,ISO)
titanium dioxide  (EXP,ISO)
TMC-120A  (ISO)
tobramycin  (ISO)
tocopherol  (EXP)
tofacitinib  (ISO)
tolterodine tartrate  (ISO)
toluene  (ISO)
toluene 2,4-diisocyanate  (ISO)
Tomentosin  (ISO)
topotecan  (EXP)
tramadol  (EXP)
tranilast  (EXP)
trans-anethole  (EXP,ISO)
trans-caffeic acid  (EXP,ISO)
trans-chalcone  (ISO)
trans-cinnamic acid  (ISO)
trans-ferulic acid  (ISO)
trans-isoeugenol  (ISO)
trans-piceid  (EXP,ISO)
trans-rhaponticin  (EXP)
trans-urocanic acid  (ISO)
trelagliptin  (ISO)
triamcinolone acetonide  (EXP,ISO)
tribromoethanol  (EXP)
tributylstannane  (EXP,ISO)
tributyrin  (EXP)
trichloroacetic acid  (ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triclocarban  (ISO)
triclosan  (ISO)
Trienomycin A  (ISO)
trierixin  (ISO)
trilobatin  (ISO)
trimellitic anhydride  (ISO)
trimethylarsine oxide  (ISO)
trimethyltin  (EXP,ISO)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
triptonide  (ISO)
troglitazone  (EXP,ISO)
troleandomycin  (ISO)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (ISO)
tropisetron  (EXP,ISO)
trovafloxacin  (EXP,ISO)
Tryptanthrine  (ISO)
tungsten  (EXP,ISO)
Tungsten carbide  (ISO)
tunicamycin  (ISO)
Tylophorine  (ISO)
tyloxapol  (ISO)
tyrphostin AG 1478  (ISO)
U-73122  (ISO)
ubiquinones  (ISO)
umbelliferone  (EXP)
undecan-2-one  (EXP,ISO)
uranium atom  (EXP,ISO)
urethane  (EXP)
urocanic acid  (ISO)
ursodeoxycholic acid  (EXP,ISO)
ursolic acid  (EXP,ISO)
usnic acid  (ISO)
vadimezan  (EXP,ISO)
valdecoxib  (EXP)
valproic acid  (EXP,ISO)
valsartan  (EXP,ISO)
vanadium atom  (EXP,ISO)
vanadium(0)  (EXP,ISO)
vancomycin  (ISO)
vanillin  (EXP,ISO)
vanoxerine dihydrochloride  (ISO)
vemurafenib  (ISO)
venom  (ISO)
verapamil  (EXP,ISO)
verbascose  (ISO)
verteporfin  (ISO)
very-low-density lipoprotein triglyceride  (ISO)
vildagliptin  (ISO)
vincamine  (ISO)
vinclozolin  (EXP)
vincristine  (EXP,ISO)
vinorelbine  (ISO)
Vinpocetine  (EXP,ISO)
vitamin D  (EXP,ISO)
vitamin E  (EXP,ISO)
vitamin K  (EXP)
vorinostat  (ISO)
VX-745  (ISO)
Walleminone  (ISO)
warfarin  (EXP)
water  (EXP,ISO)
wedelolactone  (EXP,ISO)
WIN 55212-2  (EXP,ISO)
withaferin A  (EXP,ISO)
wogonin  (EXP,ISO)
wortmannin  (EXP,ISO)
xanthohumol  (ISO)
xyloglucan  (ISO)
Y-27632  (ISO)
Yangonin  (ISO)
yohimbine  (EXP)
Z-Val-Phe-H  (ISO)
zafirlukast  (ISO)
zaragozic acid A  (EXP,ISO)
zearalenone  (EXP,ISO)
zerumbone  (ISO)
zidovudine  (EXP,ISO)
zileuton  (ISO)
zinc atom  (EXP,ISO)
zinc dichloride  (EXP,ISO)
zinc molecular entity  (EXP)
zinc nitrate  (ISO)
zinc oxide  (EXP,ISO)
zinc protoporphyrin  (EXP,ISO)
zinc pyrithione  (ISO)
zinc sulfate  (EXP,ISO)
zinc(0)  (EXP,ISO)
zineb  (ISO)
zingerone  (EXP,ISO)
zingiberene  (EXP)
ziram  (ISO)
zoledronic acid  (ISO)
zotarolimus  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ morphogenesis  (ISO)
antiviral innate immune response  (ISO)
apoptotic signaling pathway  (ISO)
calcium-mediated signaling  (IDA)
cell surface receptor signaling pathway via JAK-STAT  (IDA)
cellular extravasation  (ISO)
cellular response to amino acid stimulus  (ISO)
cellular response to amyloid-beta  (IEP)
cellular response to ionizing radiation  (ISO)
cellular response to lipopolysaccharide  (IEP,IMP,ISO)
cellular response to molecule of bacterial origin  (IEP)
cellular response to nicotine  (ISO)
cellular response to retinoic acid  (IEP)
cellular response to toxic substance  (IEP)
cellular response to type II interferon  (IEP,ISO)
chronic inflammatory response to antigenic stimulus  (ISO)
circadian rhythm  (IEP)
defense response  (ISO)
defense response to bacterium  (ISO)
defense response to Gram-positive bacterium  (ISO)
detection of mechanical stimulus involved in sensory perception of pain  (IMP)
embryonic digestive tract development  (ISO)
endothelial cell apoptotic process  (ISO)
epithelial cell proliferation involved in salivary gland morphogenesis  (ISO)
extracellular matrix organization  (ISO)
extrinsic apoptotic signaling pathway  (ISO)
extrinsic apoptotic signaling pathway via death domain receptors  (IBA,ISO)
glucose metabolic process  (ISO)
humoral immune response  (ISO)
immune response  (IEA)
inflammatory response  (ISO)
inflammatory response to wounding  (ISO)
intrinsic apoptotic signaling pathway in response to DNA damage  (ISO)
JNK cascade  (ISO)
leukocyte migration  (ISO)
leukocyte tethering or rolling  (ISO)
liver regeneration  (IEP)
macrophage activation involved in immune response  (ISO)
microglial cell activation  (ISO)
necroptotic signaling pathway  (IEA,ISO,ISS)
negative regulation of alkaline phosphatase activity  (ISO)
negative regulation of amyloid-beta clearance  (ISO)
negative regulation of apoptotic process  (IDA)
negative regulation of apoptotic signaling pathway  (ISO)
negative regulation of bicellular tight junction assembly  (ISO)
negative regulation of bile acid secretion  (IDA)
negative regulation of blood vessel endothelial cell migration  (ISO)
negative regulation of branching involved in lung morphogenesis  (ISO)
negative regulation of cell population proliferation  (IDA)
negative regulation of cytokine production involved in immune response  (ISO)
negative regulation of D-glucose import  (IDA,ISO)
negative regulation of DNA-templated transcription  (ISO)
negative regulation of endothelial cell proliferation  (ISO)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  (ISO)
negative regulation of fat cell differentiation  (IDA)
negative regulation of gene expression  (ISO)
negative regulation of heart rate  (IMP)
negative regulation of interleukin-6 production  (ISO)
negative regulation of L-glutamate import across plasma membrane  (IDA)
negative regulation of lipid catabolic process  (ISO)
negative regulation of mitotic cell cycle  (ISO)
negative regulation of myelination  (IMP)
negative regulation of myoblast differentiation  (ISO)
negative regulation of osteoblast differentiation  (ISO)
negative regulation of oxidative phosphorylation  (IDA)
negative regulation of protein-containing complex disassembly  (ISO)
negative regulation of signaling receptor activity  (ISO)
negative regulation of systemic arterial blood pressure  (IMP)
negative regulation of transcription by RNA polymerase II  (ISO)
negative regulation of vascular wound healing  (ISO)
negative regulation of viral genome replication  (ISO)
osteoclast differentiation  (ISO)
phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO)
positive regulation of action potential  (IDA)
positive regulation of amide metabolic process  (ISO)
positive regulation of amyloid-beta formation  (ISO)
positive regulation of apoptotic process  (IMP,ISO)
positive regulation of blood microparticle formation  (ISO)
positive regulation of calcidiol 1-monooxygenase activity  (ISO)
positive regulation of calcineurin-NFAT signaling cascade  (ISO)
positive regulation of canonical NF-kappaB signal transduction  (IBA,IDA,IGI,ISO)
positive regulation of cell adhesion  (ISO)
positive regulation of cell population proliferation  (IEA)
positive regulation of chemokine (C-X-C motif) ligand 2 production  (ISO)
positive regulation of chemokine production  (ISO)
positive regulation of chronic inflammatory response to antigenic stimulus  (ISO)
positive regulation of cysteine-type endopeptidase activity  (ISO)
positive regulation of cytokine production  (ISO)
positive regulation of cytokine production involved in inflammatory response  (ISO)
positive regulation of DNA biosynthetic process  (IDA)
positive regulation of DNA-binding transcription factor activity  (ISO)
positive regulation of DNA-templated transcription  (ISO)
positive regulation of endothelial cell apoptotic process  (ISO)
positive regulation of estradiol secretion  (ISO)
positive regulation of extrinsic apoptotic signaling pathway  (IBA,IMP)
positive regulation of fever generation  (ISO)
positive regulation of fractalkine production  (IDA)
positive regulation of gene expression  (IDA,IMP,ISO)
positive regulation of glial cell proliferation  (ISO)
positive regulation of hair follicle development  (ISO)
positive regulation of hepatocyte proliferation  (IDA,IMP)
positive regulation of heterotypic cell-cell adhesion  (ISO)
positive regulation of humoral immune response mediated by circulating immunoglobulin  (ISO)
positive regulation of I-kappaB phosphorylation  (ISO)
positive regulation of interleukin-1 beta production  (ISO)
positive regulation of interleukin-18 production  (IMP)
positive regulation of interleukin-33 production  (ISO)
positive regulation of interleukin-6 production  (IDA,IMP,ISO)
positive regulation of interleukin-8 production  (ISO)
positive regulation of JNK cascade  (ISO)
positive regulation of JUN kinase activity  (ISO)
positive regulation of leukocyte adhesion to arterial endothelial cell  (ISO)
positive regulation of leukocyte adhesion to vascular endothelial cell  (ISO)
positive regulation of lipid metabolic process  (ISO)
positive regulation of MAP kinase activity  (ISO)
positive regulation of MAPK cascade  (ISO)
positive regulation of membrane protein ectodomain proteolysis  (ISO)
positive regulation of miRNA transcription  (ISO)
positive regulation of mitotic nuclear division  (IMP)
positive regulation of neuron apoptotic process  (IMP,ISO)
positive regulation of neutrophil activation  (IMP)
positive regulation of NF-kappaB transcription factor activity  (ISO,ISS)
positive regulation of nitric oxide biosynthetic process  (ISO)
positive regulation of nitric-oxide synthase activity  (IMP)
positive regulation of non-canonical NF-kappaB signal transduction  (ISO)
positive regulation of osteoclast differentiation  (ISO)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IMP,ISO)
positive regulation of podosome assembly  (ISO)
positive regulation of programmed cell death  (ISO)
positive regulation of protein catabolic process  (ISO)
positive regulation of protein localization to cell surface  (ISO)
positive regulation of protein localization to plasma membrane  (IMP,ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of protein transport  (IDA,ISO)
positive regulation of protein-containing complex assembly  (ISO)
positive regulation of protein-containing complex disassembly  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of synaptic transmission  (IMP,ISO)
positive regulation of synoviocyte proliferation  (ISO)
positive regulation of transcription by RNA polymerase II  (IDA,IMP,ISO)
positive regulation of translational initiation by iron  (ISO)
positive regulation of type II interferon production  (ISO)
positive regulation of vascular associated smooth muscle cell proliferation  (ISO)
positive regulation of vitamin D biosynthetic process  (ISO)
protein localization to plasma membrane  (ISO)
regulation of biological quality  (IEA)
regulation of branching involved in salivary gland morphogenesis  (ISO)
regulation of canonical NF-kappaB signal transduction  (ISO)
regulation of cell population proliferation  (IDA,ISO)
regulation of developmental process  (IEA)
regulation of endothelial cell apoptotic process  (ISO)
regulation of establishment of endothelial barrier  (ISO)
regulation of fat cell differentiation  (ISO)
regulation of immunoglobulin production  (ISO)
regulation of inflammatory response  (ISO)
regulation of insulin secretion  (ISO)
regulation of membrane lipid metabolic process  (ISO)
regulation of metabolic process  (ISO)
regulation of multicellular organismal process  (IEA)
regulation of osteoclast differentiation  (ISO)
regulation of protein phosphorylation  (ISO)
regulation of protein secretion  (ISO)
regulation of reactive oxygen species metabolic process  (ISO)
regulation of secretion  (IEA)
regulation of synapse organization  (ISO)
response to 3,3',5-triiodo-L-thyronine  (IEP)
response to activity  (IEP)
response to bacterium  (IEP)
response to ethanol  (IEP)
response to fructose  (IEP)
response to glucocorticoid  (ISO)
response to gold nanoparticle  (IEP)
response to Gram-negative bacterium  (IEP)
response to hypoxia  (IEP)
response to isolation stress  (IEP)
response to L-glutamate  (IDA)
response to lipopolysaccharide  (IEP,IMP)
response to macrophage colony-stimulating factor  (IEP)
response to mechanical stimulus  (IEP)
response to nutrient levels  (IEP)
response to virus  (ISO)
response to xenobiotic stimulus  (IEP)
sequestering of triglyceride  (ISO)
skeletal muscle contraction  (IEP)
toll-like receptor 3 signaling pathway  (IMP)
tumor necrosis factor-mediated signaling pathway  (IBA,IMP,ISO)
vascular endothelial growth factor production  (IEA,ISO,ISS)
vasodilation  (IMP)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
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382. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
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408. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
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410. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
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430. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
431. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
432. Comprehensive gene review and curation RGD comprehensive gene curation
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Additional References at PubMed
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PMID:8224868   PMID:8383325   PMID:8395024   PMID:8879212   PMID:9223320   PMID:9305915   PMID:9343261   PMID:9368616   PMID:9435233   PMID:9834074   PMID:10383454   PMID:10443688  
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PMID:11101870   PMID:11168643   PMID:11241200   PMID:11374864   PMID:11477479   PMID:11577081   PMID:11588035   PMID:11686853   PMID:11728336   PMID:11770045   PMID:11793965   PMID:11799106  
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PMID:16702408   PMID:16705482   PMID:16723520   PMID:16730193   PMID:16762003   PMID:16803872   PMID:16806015   PMID:16813528   PMID:16840655   PMID:16864744   PMID:16874877   PMID:16882655  
PMID:16886721   PMID:16895791   PMID:16923814   PMID:16926404   PMID:16934751   PMID:16949134   PMID:17009398   PMID:17010968   PMID:17015619   PMID:17046730   PMID:17048691   PMID:17053043  
PMID:17070605   PMID:17109621   PMID:17151266   PMID:17158358   PMID:17161388   PMID:17166735   PMID:17170233   PMID:17170234   PMID:17242187   PMID:17255335   PMID:17278014   PMID:17327883  
PMID:17336456   PMID:17337591   PMID:17346684   PMID:17350185   PMID:17379754   PMID:17380194   PMID:17389591   PMID:17405916   PMID:17416605   PMID:17433709   PMID:17475835   PMID:17486449  
PMID:17531209   PMID:17553348   PMID:17568197   PMID:17573461   PMID:17582939   PMID:17592532   PMID:17640624   PMID:17659374   PMID:17670746   PMID:17673218   PMID:17675574   PMID:17690839  
PMID:17692605   PMID:17693256   PMID:17698507   PMID:17712964   PMID:17845533   PMID:17867433   PMID:17873284   PMID:17873291   PMID:17873366   PMID:17874178   PMID:17883399   PMID:17884764  
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PMID:18180165   PMID:18187553   PMID:18201371   PMID:18202225   PMID:18223607   PMID:18261938   PMID:18279700   PMID:18288929   PMID:18299267   PMID:18303625   PMID:18303626   PMID:18303642  
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PMID:19555759   PMID:19567204   PMID:19596989   PMID:19627007   PMID:19628795   PMID:19641635   PMID:19651533   PMID:19653348   PMID:19655406   PMID:19666842   PMID:19667008   PMID:19714640  
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PMID:19861263   PMID:19940035   PMID:19940926   PMID:19942300   PMID:19948415   PMID:19969084   PMID:19997621   PMID:20034812   PMID:20035858   PMID:20041225   PMID:20051532   PMID:20060382  
PMID:20067418   PMID:20080598   PMID:20092780   PMID:20111901   PMID:20120734   PMID:20133817   PMID:20141500   PMID:20159696   PMID:20180411   PMID:20180418   PMID:20196785   PMID:20202754  
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Genomics

Comparative Map Data
Tnf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8203,626,685 - 3,629,303 (+)NCBIGRCr8
mRatBN7.2203,622,011 - 3,624,629 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl203,622,011 - 3,624,629 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,321,864 - 4,324,463 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0203,683,924 - 3,686,523 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,221,516 - 4,224,112 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0205,189,382 - 5,192,000 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,189,390 - 5,192,000 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,855,829 - 4,858,447 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,936,229 - 6,938,847 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,661,000 - 3,663,618 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera204,400,860 - 4,403,478 (-)NCBICelera
RH 3.4 Map20 RGD
Cytogenetic Map20p12NCBI
TNF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38631,575,565 - 31,578,336 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl631,575,565 - 31,578,336 (+)EnsemblGRCh38hg38GRCh38
GRCh37631,543,342 - 31,546,113 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,651,329 - 31,654,091 (+)NCBINCBI36Build 36hg18NCBI36
Build 34631,651,328 - 31,654,091NCBI
Celera633,141,565 - 33,144,327 (+)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef631,330,078 - 31,332,847 (+)NCBIHuRef
CHM1_1631,545,476 - 31,548,245 (+)NCBICHM1_1
T2T-CHM13v2.0631,428,617 - 31,431,388 (+)NCBIT2T-CHM13v2.0
Tnf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,418,343 - 35,420,983 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1735,418,357 - 35,420,983 (-)EnsemblGRCm39 Ensembl
GRCm381735,199,367 - 35,202,007 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,199,381 - 35,202,007 (-)EnsemblGRCm38mm10GRCm38
MGSCv371735,336,335 - 35,338,941 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,807,442 - 34,810,048 (-)NCBIMGSCv36mm8
Celera1738,296,090 - 38,298,699 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.59NCBI
Tnf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955437117,206 - 120,700 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955437117,267 - 119,899 (+)NCBIChiLan1.0ChiLan1.0
TNF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,052,507 - 46,055,280 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1642,014,074 - 42,016,847 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,236,650 - 31,239,423 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,126,618 - 32,129,389 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,126,618 - 32,129,381 (+)Ensemblpanpan1.1panPan2
TNF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,074,561 - 1,076,425 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,074,552 - 1,076,425 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,211,002 - 1,212,867 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,219,807 - 1,221,672 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,219,798 - 1,221,672 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,078,543 - 1,080,407 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,146,468 - 1,148,336 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,213,251 - 1,215,120 (+)NCBIUU_Cfam_GSD_1.0
Tnf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494635,623,427 - 35,626,009 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367271,936,066 - 1,937,766 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367271,936,066 - 1,937,766 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl723,699,628 - 23,702,416 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1723,699,635 - 23,702,393 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2727,549,619 - 27,552,377 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap7p11-q11NCBI
TNF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366604431,477,411 - 31,480,675 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tnf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475424,623,425 - 24,625,531 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475424,623,059 - 24,625,647 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tnf
42 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:312
Count of miRNA genes:181
Interacting mature miRNAs:209
Transcripts:ENSRNOT00000001110
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2306850Pia40Pristane induced arthritis QTL 400.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2015279595304575Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
61448Ciaa1CIA Autoantibody QTL 1300.001blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)2026463954597031Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
61472Aia1Adjuvant induced arthritis QTL 1180.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2026463954597031Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126123605Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362164910078919Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2036216499243559Rat
724519Bp144Blood pressure QTL 1440.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2013624629Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20362165614101050Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
737973Pia21Pristane induced arthritis QTL 214.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)2036216564606812Rat

Markers in Region
D20Kyo1   No map positions available.
D20Wox2  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map2048.4UniSTS
RH 3.4 Map2048.4RGD
RH 2.0 Map2033.3RGD
Cytogenetic Map20p12UniSTS
D20Wox3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,621,656 - 3,621,771 (+)MAPPERmRatBN7.2
mRatBN7.2203,621,656 - 3,621,771 (-)MAPPERmRatBN7.2
Rnor_6.0205,192,240 - 5,192,354NCBIRnor6.0
Rnor_6.0204,855,475 - 4,855,589NCBIRnor6.0
Rnor_5.0206,935,875 - 6,935,989UniSTSRnor5.0
RGSC_v3.4203,660,646 - 3,660,760UniSTSRGSC3.4
RGSC_v3.1203,660,872 - 3,660,987RGD
Celera204,403,718 - 4,403,832UniSTS
Cytogenetic Map20p12UniSTS
D20UW1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,621,649 - 3,621,791 (-)MAPPERmRatBN7.2
mRatBN7.2203,621,649 - 3,621,791 (+)MAPPERmRatBN7.2
Rnor_6.0205,192,220 - 5,192,361NCBIRnor6.0
Rnor_6.0204,855,468 - 4,855,609NCBIRnor6.0
Rnor_5.0206,935,868 - 6,936,009UniSTSRnor5.0
RGSC_v3.4203,660,638 - 3,660,780RGDRGSC3.4
RGSC_v3.4203,660,639 - 3,660,780UniSTSRGSC3.4
RGSC_v3.1203,660,865 - 3,661,007RGD
Celera204,403,698 - 4,403,839UniSTS
RH 3.4 Map2044.5RGD
RH 3.4 Map2044.5UniSTS
RH 2.0 Map2028.3RGD
SHRSP x BN Map200.0UniSTS
SHRSP x BN Map200.0RGD
FHH x ACI Map200.16RGD
Cytogenetic Map20p12UniSTS
D20Ztm1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,621,599 - 3,621,773 (+)MAPPERmRatBN7.2
mRatBN7.2203,621,599 - 3,621,773 (-)MAPPERmRatBN7.2
Rnor_6.0205,192,238 - 5,192,411NCBIRnor6.0
Rnor_6.0204,855,418 - 4,855,591NCBIRnor6.0
Rnor_5.0206,935,818 - 6,935,991UniSTSRnor5.0
RGSC_v3.4203,660,589 - 3,660,762UniSTSRGSC3.4
Celera204,403,716 - 4,403,889UniSTS
Cytogenetic Map20p12UniSTS
AI113237  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,620,478 - 3,620,693 (+)MAPPERmRatBN7.2
mRatBN7.2203,620,478 - 3,620,693 (-)MAPPERmRatBN7.2
Rnor_6.0205,193,318 - 5,193,532NCBIRnor6.0
Rnor_6.0204,854,297 - 4,854,511NCBIRnor6.0
Rnor_5.0206,934,697 - 6,934,911UniSTSRnor5.0
RGSC_v3.4203,659,468 - 3,659,682UniSTSRGSC3.4
Celera204,404,796 - 4,405,010UniSTS
Cytogenetic Map20p12UniSTS
PMC112151P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,623,059 - 3,623,529 (+)MAPPERmRatBN7.2
mRatBN7.2203,623,059 - 3,623,529 (-)MAPPERmRatBN7.2
Rnor_6.0205,190,482 - 5,190,951NCBIRnor6.0
Rnor_6.0204,856,878 - 4,857,347NCBIRnor6.0
Rnor_5.0206,937,278 - 6,937,747UniSTSRnor5.0
RGSC_v3.4203,662,049 - 3,662,518UniSTSRGSC3.4
Celera204,401,960 - 4,402,429UniSTS
Cytogenetic Map20p12UniSTS
PMC116546P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,623,530 - 3,623,701 (+)MAPPERmRatBN7.2
mRatBN7.2203,623,530 - 3,623,701 (-)MAPPERmRatBN7.2
Rnor_6.0205,190,310 - 5,190,480NCBIRnor6.0
Rnor_6.0204,857,349 - 4,857,519NCBIRnor6.0
Rnor_5.0206,937,749 - 6,937,919UniSTSRnor5.0
RGSC_v3.4203,662,520 - 3,662,690UniSTSRGSC3.4
Celera204,401,788 - 4,401,958UniSTS
Cytogenetic Map20p12UniSTS
Tnf  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.4203,662,374 - 3,662,767UniSTSRGSC3.4
RGSC_v3.4203,661,240 - 3,662,597UniSTSRGSC3.4
Celera204,401,711 - 4,402,104UniSTS
RH94729  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,624,197 - 3,624,375 (+)MAPPERmRatBN7.2
mRatBN7.2203,624,197 - 3,624,375 (-)MAPPERmRatBN7.2
Rnor_6.0205,189,636 - 5,189,813NCBIRnor6.0
Rnor_6.0204,858,016 - 4,858,193NCBIRnor6.0
Rnor_5.0206,938,416 - 6,938,593UniSTSRnor5.0
RGSC_v3.4203,663,187 - 3,663,364UniSTSRGSC3.4
Celera204,401,114 - 4,401,291UniSTS
Cytogenetic Map20p12UniSTS
RH94730  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,621,658 - 3,621,793 (+)MAPPERmRatBN7.2
mRatBN7.2203,621,658 - 3,621,793 (-)MAPPERmRatBN7.2
Rnor_6.0205,192,218 - 5,192,352NCBIRnor6.0
Rnor_6.0204,855,477 - 4,855,611NCBIRnor6.0
Rnor_5.0206,935,877 - 6,936,011UniSTSRnor5.0
RGSC_v3.4203,660,648 - 3,660,782UniSTSRGSC3.4
Celera204,403,696 - 4,403,830UniSTS
Cytogenetic Map20p12UniSTS
RH94817  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,622,694 - 3,623,024 (+)MAPPERmRatBN7.2
mRatBN7.2203,622,694 - 3,623,024 (-)MAPPERmRatBN7.2
Rnor_6.0205,190,987 - 5,191,316NCBIRnor6.0
Rnor_6.0204,856,513 - 4,856,842NCBIRnor6.0
Rnor_5.0206,936,913 - 6,937,242UniSTSRnor5.0
RGSC_v3.4203,661,684 - 3,662,013UniSTSRGSC3.4
Celera204,402,465 - 4,402,794UniSTS
RH 3.4 Map2051.3UniSTS
Cytogenetic Map20p12UniSTS
RH138655  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,624,360 - 3,624,532 (+)MAPPERmRatBN7.2
mRatBN7.2203,624,360 - 3,624,532 (-)MAPPERmRatBN7.2
Rnor_6.0205,189,479 - 5,189,650NCBIRnor6.0
Rnor_6.0204,858,179 - 4,858,350NCBIRnor6.0
Rnor_5.0206,938,579 - 6,938,750UniSTSRnor5.0
RGSC_v3.4203,663,350 - 3,663,521UniSTSRGSC3.4
Celera204,400,957 - 4,401,128UniSTS
RH 3.4 Map2050.9UniSTS
Cytogenetic Map20p12UniSTS
PMC26794P3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,623,058 - 3,623,730 (+)MAPPERmRatBN7.2
mRatBN7.2203,623,058 - 3,623,730 (-)MAPPERmRatBN7.2
Rnor_6.0205,190,281 - 5,190,952NCBIRnor6.0
Rnor_6.0204,856,877 - 4,857,548NCBIRnor6.0
Rnor_5.0206,937,277 - 6,937,948UniSTSRnor5.0
RGSC_v3.4203,662,048 - 3,662,719UniSTSRGSC3.4
Celera204,401,759 - 4,402,430UniSTS
Cytogenetic Map20p12UniSTS
UniSTS:463959  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2203,622,863 - 3,623,794 (+)MAPPERmRatBN7.2
mRatBN7.2203,622,863 - 3,623,794 (-)MAPPERmRatBN7.2
Rnor_6.0205,190,217 - 5,191,147NCBIRnor6.0
Rnor_6.0204,856,682 - 4,857,612NCBIRnor6.0
Rnor_5.0206,937,082 - 6,938,012UniSTSRnor5.0
RGSC_v3.4203,661,853 - 3,662,783UniSTSRGSC3.4
Celera204,401,695 - 4,402,625UniSTS
Cytogenetic Map20p12UniSTS
Tnf  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.0206,937,603 - 6,937,996UniSTSRnor5.0
RGSC_v3.4203,662,374 - 3,662,767UniSTSRGSC3.4
Celera204,401,711 - 4,402,104UniSTS
Cytogenetic Map20p12UniSTS
Tnf  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.0206,936,469 - 6,937,826UniSTSRnor5.0
RGSC_v3.4203,661,240 - 3,662,597UniSTSRGSC3.4
Cytogenetic Map20p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
12 12 55 66 58 34 13 34 12 115 49 31 20 36 24

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_012675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC094348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF269159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF269160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF329982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF329983 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF329984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF329985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF329986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF329987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ002278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY427673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY427674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY427675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC107671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX883046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D00475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ201305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L00981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L19123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X66539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000001110   ⟹   ENSRNOP00000001110
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl203,622,011 - 3,624,629 (+)Ensembl
Rnor_6.0 Ensembl204,855,829 - 4,858,447 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000079677   ⟹   ENSRNOP00000074520
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl203,622,011 - 3,623,794 (+)Ensembl
Rnor_6.0 Ensembl205,189,390 - 5,192,000 (-)Ensembl
RefSeq Acc Id: NM_012675   ⟹   NP_036807
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8203,626,685 - 3,629,303 (+)NCBI
mRatBN7.2203,622,011 - 3,624,629 (+)NCBI
Rnor_6.0205,189,382 - 5,192,000 (-)NCBI
Rnor_5.0206,936,229 - 6,938,847 (+)NCBI
RGSC_v3.4203,661,000 - 3,663,618 (+)RGD
Celera204,400,860 - 4,403,478 (-)RGD
Sequence:
RefSeq Acc Id: NP_036807   ⟸   NM_012675
- UniProtKB: Q9JI26 (UniProtKB/Swiss-Prot),   Q6EE11 (UniProtKB/Swiss-Prot),   Q9JI27 (UniProtKB/Swiss-Prot),   P16599 (UniProtKB/Swiss-Prot),   A6KTW8 (UniProtKB/TrEMBL),   E7DB74 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000074520   ⟸   ENSRNOT00000079677
Ensembl Acc Id: ENSRNOP00000001110   ⟸   ENSRNOT00000001110
Protein Domains
THD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P16599-F1-model_v2 AlphaFold P16599 1-235 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3876 AgrOrtholog
BioCyc Gene G2FUF-4660 BioCyc
Ensembl Genes ENSRNOG00000000837 Ensembl
  ENSRNOG00000055156 Ensembl
  ENSRNOG00000070745 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055008022 UniProtKB/Swiss-Prot
  ENSRNOG00060004712 UniProtKB/Swiss-Prot
  ENSRNOG00065031842 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000001110.6 UniProtKB/Swiss-Prot
  ENSRNOT00000079677.2 UniProtKB/TrEMBL
  ENSRNOT00055013522 UniProtKB/Swiss-Prot
  ENSRNOT00060007886 UniProtKB/Swiss-Prot
  ENSRNOT00065054848 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.120.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7938033 IMAGE-MGC_LOAD
InterPro TNF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNF_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNF_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNF_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tumour_necrosis_fac-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:24835 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:124630 IMAGE-MGC_LOAD
NCBI Gene 24835 ENTREZGENE
PANTHER PTHR11471:SF23 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TUMOR NECROSIS FACTOR FAMILY MEMBER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TNF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB TNF RGD
PhenoGen Tnf PhenoGen
PRINTS TNECROSISFCT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNFALPHA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE TNF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TNF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000837 RatGTEx
  ENSRNOG00000055156 RatGTEx
  ENSRNOG00000070745 RatGTEx
  ENSRNOG00055008022 RatGTEx
  ENSRNOG00060004712 RatGTEx
  ENSRNOG00065031842 RatGTEx
SMART TNF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49842 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2URC2_RAT UniProtKB/TrEMBL
  A6KTW7_RAT UniProtKB/TrEMBL
  A6KTW8 ENTREZGENE, UniProtKB/TrEMBL
  E7DB74 ENTREZGENE, UniProtKB/TrEMBL
  P16599 ENTREZGENE
  Q6EE11 ENTREZGENE
  Q9JI26 ENTREZGENE
  Q9JI27 ENTREZGENE
  TNFA_RAT UniProtKB/Swiss-Prot
UniProt Secondary Q6EE11 UniProtKB/Swiss-Prot
  Q9JI26 UniProtKB/Swiss-Prot
  Q9JI27 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Tnf  tumor necrosis factor  LOC103694380  tumor necrosis factor-like  Data merged from RGD:9404643 737654 PROVISIONAL
2016-07-20 LOC103694380  tumor necrosis factor-like  LOC103694380  tumor necrosis factor  Name changed 629549 APPROVED
2014-08-25 LOC103694380  tumor necrosis factor      Symbol and Name status set to provisional 70820 PROVISIONAL
2011-08-01 Tnf  tumor necrosis factor  Tnf  tumor necrosis factor (TNF superfamily, member 2)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Tnf  tumor necrosis factor (TNF superfamily, member 2)    tumor necrosis factor superfamily, member 2  Name updated 1299863 APPROVED
2004-12-14 Tnf  tumor necrosis factor superfamily, member 2    tumor necrosis factor superfamily, member 2  Symbol and Name status set to approved 1299863 APPROVED
2002-06-10 Tnf  tumor necrosis factor superfamily, member 2      Name updated 70585 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
null may function in early response to nerve injury occurring distal to the cell body  
gene_disease cosegregates with various cardiovascular phenotypes and body mass in GH x BN F2 hybrids 1357163
gene_disease may be involved in insulin resistance; coadministration with insulin mimics human type II diabetes 1358946
gene_drugs injection of endotoxin, a lipopolysaccaride, increases the mRNA level in muscles 628388
gene_drugs ebselen,a seleno-organic compound, significantly reduces mRNA and protein levels in lung and cronchoalveolar lavage 628388
gene_expression expression increases after endotoxin administration resulting in decrease in body temperature 70589
gene_expression expressed in brain, somatotropes and neurointermediate lobes of pituitary 628388
gene_expression estrogen induces apoptotic function and may be involved in regulation of anterior pituitary cell renewal during estrous cylce 628388
gene_function cytokine 625679
gene_function cytokine 628388
gene_mapping found in the major histocompatibility RT1 complex 1300431
gene_process involved in host defense, cell proliferation, differentiation and death 625679
gene_process plays a role in initiating and regulating the cytosine cascade 625679
gene_process involved in body temperature response to endotoxin 61505
gene_process inhibits protein synthesis and myogenesis in myoblasts, activates nuclear facotr-kappa B in the myotubes 628388
gene_process decreases viability of anterior pituitary cells in females and induces apoptosis in somatotope and lactotrope cells from female rats 628388
gene_process proinflammatory cytokine responsible for muscle catabolism 628388
gene_process Tnfr1 (p60) and Tnfr2 (p80) mediated transcytosis an inflammatory response in blood-brain barrier, takes place under native conditions 628388
gene_process activates the ubiquitin-proteasome pathway 628388
gene_process proinflammatory cytokine acting as a signalling molecule in immune-neuro-endocrine network 628388
gene_regulation production increased on enhanced activation of ERK1/2 and Egr-1 by LPS after chronic ethanol feeding 70589
gene_regulation expression was decreased in cerebellum from F344 animals (20-month-old) on 6 weeks of a spinach-enriched diet 628388