GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | deguelin inhibits the reaction [TNF protein results in increased export of CSF1R protein] | PMID:34126350 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | deguelin inhibits the reaction [TNF protein affects the localization of and results in increased phosphorylation of RELA protein]; deguelin inhibits the reaction [TNF protein results in increased cleavage of PARP1 protein]; deguelin inhibits the reaction [TNF protein results in increased degradation of and results in increased phosphorylation of NFKBIA protein]; deguelin inhibits the reaction [TNF protein results in increased expression of BCL2 mRNA]; deguelin inhibits the reaction [TNF protein results in increased expression of BCL2L1 mRNA]; deguelin inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; deguelin inhibits the reaction [TNF protein results in increased expression of CCND1 protein]; deguelin inhibits the reaction [TNF protein results in increased expression of CFLAR mRNA]; deguelin inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; deguelin inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; deguelin inhibits the reaction [TNF protein results in increased expression of MMP9 protein]; deguelin inhibits the reaction [TNF protein results in increased expression of MUC mRNA]; deguelin inhibits the reaction [TNF protein results in increased expression of MYC protein]; deguelin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]; deguelin inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; deguelin inhibits the reaction [TNF protein results in increased expression of TSLP mRNA]; deguelin inhibits the reaction [TNF protein results in increased phosphorylation of and affects the localization of RELA protein]; deguelin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; deguelin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein] | PMID:17015749 PMID:22623043 PMID:28529457 | |
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