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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3876
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: CHEBI:68637
Term: dexamethasone phosphate
Definition: A steroid phosphate that is the 21-O-phospho derivative of dexamethasone.
Chemical ID: MESH:C004180
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfmultiple interactionsEXP 6480464CTDdexamethasone 21-phosphate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]PMID:36996615
Tnfmultiple interactionsISOTNF (Homo sapiens)6480464CTDdexamethasone 21-phosphate inhibits the reaction [TNF protein promotes the reaction [kallidin, des-Arg(10)- binds to BDKRB1 protein]]PMID:17931716
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