GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | increases expression | EXP | | 6480464 | CTD | 1-Naphthylisothiocyanate results in increased expression of TNF mRNA; 1-Naphthylisothiocyanate results in increased expression of TNF protein | PMID:15135310 PMID:18364083 PMID:18590720 PMID:25051504 PMID:25418378 PMID:32198087 | Tnf | multiple interactions | EXP | | 6480464 | CTD | Dexamethasone inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF protein]; Emodin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF protein]; ginsenoside Rg1 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF protein]; Resveratrol inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF protein]; Ursodeoxycholic Acid affects the reaction [1-Naphthylisothiocyanate results in increased expression of TNF protein]; Ursodeoxycholic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF protein] | PMID:18590720 PMID:25418378 PMID:32198087 | Tnf | increases expression | ISO | Tnf (Mus musculus) | 6480464 | CTD | 1-Naphthylisothiocyanate results in increased expression of TNF mRNA; 1-Naphthylisothiocyanate results in increased expression of TNF protein | PMID:29660435 PMID:30517764 PMID:33400020 PMID:33749747 PMID:36008890 | Tnf | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | [1-Naphthylisothiocyanate co-treated with Allopurinol] results in increased expression of TNF mRNA; [1-Naphthylisothiocyanate co-treated with Allopurinol] results in increased expression of TNF protein; [Hypoxanthine co-treated with potassium oxonate] inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF mRNA]; liquiritin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF protein]; NR1H4 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF mRNA]; NR1H4 promotes the reaction [yangonin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF mRNA]]; obeticholic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF mRNA]; pregna-4,17-diene-3,16-dione inhibits the reaction [yangonin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF mRNA]]; pregna-4,17-diene-3,16-dione promotes the reaction [1-Naphthylisothiocyanate results in increased expression of TNF mRNA]; SEW2871 inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF protein]; Uric Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF mRNA]; Uric Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF protein]; yangonin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF mRNA] | PMID:29660435 PMID:33400020 PMID:33749747 PMID:36008890 | | ||||||||||||||||||||||
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