GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | increases expression | EXP | | 6480464 | CTD | Carmustine results in increased expression of TNF protein | PMID:18528683 PMID:20046642 | Tnf | multiple interactions | EXP | | 6480464 | CTD | [Carmustine co-treated with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid] inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Nitrites]; [Carmustine co-treated with Buthionine Sulfoximine] inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Buthionine Sulfoximine promotes the reaction [Carmustine inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]]; Carmustine inhibits the reaction [TNF protein results in increased expression of NOS2 mRNA]; Carmustine promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; MT2 protein inhibits the reaction [Carmustine results in increased expression of TNF protein]; Nitrites inhibits the reaction [[TNF protein results in increased activity of NOS2 protein] which results in increased chemical synthesis of Carmustine]; Zinc Sulfate inhibits the reaction [Carmustine results in increased expression of TNF protein] | PMID:11970852 PMID:12433058 PMID:18528683 PMID:20046642 PMID:7532384 | Tnf | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | Carmustine promotes the reaction [Oligodeoxyribonucleotides analog results in increased secretion of TNF protein] | PMID:12477282 | | ||||||||||||||||||||||
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