GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | increases expression | EXP | | 6480464 | CTD | Norepinephrine results in increased expression of TNF mRNA | PMID:15158148 PMID:25437044 | Tnf | increases secretion | EXP | | 6480464 | CTD | Norepinephrine results in increased secretion of TNF protein | PMID:15158148 | Tnf | multiple interactions | EXP | | 6480464 | CTD | Acetylcysteine inhibits the reaction [Norepinephrine results in increased secretion of TNF protein]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased secretion of TNF protein]; Norepinephrine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]; Norepinephrine promotes the reaction [TNF protein results in increased expression of IL6 protein] | PMID:15081246 PMID:15158148 PMID:8392517 | |
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