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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3876
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: CHEBI:4489
Term: Diallyl sulfide
Definition: An organic sulfide that has formula C6H10S.
Chemical ID: MESH:C038491
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfmultiple interactionsEXP 6480464CTDallyl sulfide inhibits the reaction [Cyclophosphamide results in increased secretion of TNF protein]; allyl sulfide inhibits the reaction [Ethanol results in increased expression of TNF mRNA]; allyl sulfide inhibits the reaction [Paraquat results in increased expression of TNF mRNA]PMID:20116195 PMID:25891457 PMID:31779506
Tnfmultiple interactionsISOTnf (Mus musculus)6480464CTDallyl sulfide inhibits the reaction [[ethylene dichloride co-treated with Ethanol] results in increased expression of TNF protein]PMID:37150348
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