GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | multiple interactions | EXP | | 6480464 | CTD | oxymatrine inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; oxymatrine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; oxymatrine inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein] | PMID:15603720 PMID:23568217 PMID:35290143 | Tnf | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | oxymatrine inhibits the reaction [IL1B protein results in increased expression of TNF mRNA]; oxymatrine inhibits the reaction [IL1B protein results in increased expression of TNF protein]; oxymatrine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] | PMID:23568217 PMID:37196756 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | oxymatrine analog inhibits the reaction [TNF protein results in decreased expression of BAX protein]; oxymatrine analog inhibits the reaction [TNF protein results in increased expression of BCL2 protein]; oxymatrine analog inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]; oxymatrine analog inhibits the reaction [TNF protein results in increased expression of IL1B protein]; oxymatrine analog inhibits the reaction [TNF protein results in increased expression of IL6 protein]; oxymatrine analog inhibits the reaction [TNF protein results in increased expression of MMP1 protein]; oxymatrine analog inhibits the reaction [TNF protein results in increased expression of MMP13 protein]; oxymatrine analog inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; oxymatrine analog inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]; oxymatrine analog inhibits the reaction [TNF protein results in increased expression of RELA protein modified form] | PMID:34459104 | | ||||||||||||||||||||||
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