GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | decreases secretion | ISO | TNF (Homo sapiens) | 6480464 | CTD | Beclomethasone results in decreased secretion of TNF protein | PMID:9819297 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | Beclomethasone inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Beclomethasone inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; Beclomethasone inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Beclomethasone inhibits the reaction [TNF protein results in increased secretion of CCL5 protein]; Beclomethasone inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein] | PMID:10100995 PMID:10903220 PMID:14643170 PMID:8937731 PMID:9150321 | |
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