GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | multiple interactions | EXP | | 6480464 | CTD | Decitabine inhibits the reaction [Cadmium Chloride results in increased expression of TNF protein]; Decitabine promotes the reaction [T-2 Toxin results in decreased methylation of TNF promoter]; Decitabine promotes the reaction [T-2 Toxin results in increased expression of TNF mRNA] | PMID:22457795 PMID:31279042 | Tnf | increases expression | ISO | Tnf (Mus musculus) | 6480464 | CTD | Decitabine results in increased expression of TNF mRNA | PMID:27915011 | Tnf | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | Decitabine inhibits the reaction [[bisphenol A affects the susceptibility to [Lipopolysaccharides co-treated with IFNG protein]] which results in increased expression of TNF mRNA]; Decitabine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]; Decitabine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein] | PMID:24440346 PMID:29718165 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | [[Decitabine co-treated with TGFB1 protein] results in increased expression of FOXP3 protein] which results in increased expression of TNF protein; [Decitabine co-treated with TNF protein] promotes the reaction [GTF2H1 protein binds to IER3 promoter]; [Decitabine co-treated with TNF protein] results in increased expression of CD14 protein; TNF protein promotes the reaction [Decitabine promotes the reaction [NFKB1 protein binds to IER3 promoter]]; TNF protein promotes the reaction [Decitabine promotes the reaction [RELA protein binds to IER3 promoter]]; TNF protein promotes the reaction [Decitabine results in increased expression of IER3 mRNA]; TNF protein promotes the reaction [Decitabine results in increased expression of IRF7 protein]; TNF protein promotes the reaction [Decitabine results in increased expression of JUN protein] | PMID:18567616 PMID:19117987 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |