GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | increases response to substance | ISO | TNF (Homo sapiens) | 6480464 | CTD | TNF protein results in increased susceptibility to Dihydrotestosterone | PMID:11241555 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | [Lipopolysaccharides co-treated with Dihydrotestosterone] results in increased secretion of TNF protein; [TNF protein results in increased susceptibility to Dihydrotestosterone] which results in increased localization of AR protein; bicalutamide inhibits the reaction [Dihydrotestosterone inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; bicalutamide inhibits the reaction [Dihydrotestosterone inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]]; bicalutamide inhibits the reaction [Dihydrotestosterone inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]]; bicalutamide inhibits the reaction [Dihydrotestosterone inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]]; Dihydrotestosterone inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; Dihydrotestosterone inhibits the reaction [TNF protein results in increased expression of CD40 mRNA]; Dihydrotestosterone inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; Dihydrotestosterone inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; Dihydrotestosterone inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]; Dihydrotestosterone inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA]; Dihydrotestosterone inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA]; Dihydrotestosterone inhibits the reaction [TNF protein results in increased expression of TLR4 mRNA]; Dihydrotestosterone inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; Dihydrotestosterone inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Dihydrotestosterone inhibits the reaction [TNF protein results in increased secretion of CCL2 protein]; Dihydrotestosterone inhibits the reaction [TNF protein results in increased secretion of CSF2 protein]; Dihydrotestosterone inhibits the reaction [TNF protein results in increased secretion of CXCL1 protein]; Dihydrotestosterone inhibits the reaction [TNF protein results in increased secretion of IL6 protein] | PMID:11241555 PMID:16317058 PMID:27239218 | | ||||||||||||||||||||||
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