GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | increases expression | EXP | | 6480464 | CTD | chromium hexavalent ion results in increased expression of TNF protein | PMID:35024197 PMID:36108929 | Tnf | multiple interactions | EXP | | 6480464 | CTD | [Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of TNF protein; Ellagic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of TNF protein]; Resveratrol inhibits the reaction [chromium hexavalent ion results in increased expression of TNF protein]; S-allylcysteine inhibits the reaction [[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of TNF protein] | PMID:28988497 PMID:35024197 PMID:36108929 | Tnf | increases secretion | ISO | TNF (Homo sapiens) | 6480464 | CTD | chromium hexavalent ion results in increased secretion of TNF protein | PMID:25448439 | Tnf | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | [chromium hexavalent ion co-treated with Benzo(a)pyrene] affects the expression of TNF mRNA; [Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of TNF mRNA; Acetylcysteine inhibits the reaction [[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of TNF protein] | PMID:25820237 PMID:36880428 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | Luteolin inhibits the reaction [chromium hexavalent ion results in increased secretion of TNF protein] | PMID:25448439 | |
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