GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | decreases expression | ISO | Tnf (Mus musculus) | 6480464 | CTD | Dextromethorphan results in decreased expression of TNF protein | PMID:19189960 | Tnf | increases secretion | ISO | TNF (Homo sapiens) | 6480464 | CTD | Dextromethorphan results in increased secretion of TNF protein | PMID:32871113 | Tnf | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | Dextromethorphan inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased expression of TNF protein]; Dextromethorphan inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein] | PMID:30822415 | |
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