GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | multiple interactions | EXP | | 6480464 | CTD | Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]; Budesonide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein] | PMID:15734790 | Tnf | decreases expression | ISO | TNF (Homo sapiens) | 6480464 | CTD | Budesonide results in decreased expression of TNF protein | PMID:15589479 | Tnf | decreases secretion | ISO | TNF (Homo sapiens) | 6480464 | CTD | Budesonide results in decreased secretion of TNF protein | PMID:7621058 | Tnf | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | Budesonide inhibits the reaction [[TNF protein co-treated with IL1B protein] results in decreased susceptibility to Formoterol Fumarate]; Budesonide inhibits the reaction [[TNF protein co-treated with IL1B protein] results in decreased susceptibility to Salmeterol Xinafoate]; Budesonide inhibits the reaction [[TNF protein co-treated with IL1B protein] results in decreased susceptibility to Terbutaline]; Budesonide inhibits the reaction [[TNF protein co-treated with IL1B protein] results in increased expression of PTGS2 mRNA]; Budesonide inhibits the reaction [Ozone results in increased expression of TNF protein] | PMID:20061444 PMID:28279894 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | Budesonide inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Budesonide inhibits the reaction [TNF protein results in increased secretion of CCL5 mRNA]; Budesonide inhibits the reaction [TNF protein results in increased secretion of CCL5 protein]; Budesonide inhibits the reaction [TNF protein results in increased secretion of CXCL8 mRNA]; Budesonide inhibits the reaction [TNF protein results in increased secretion of CXCL8 protein] | PMID:10100995 PMID:10903220 PMID:14643170 | | ||||||||||||||||||||||
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