GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | increases expression | EXP | | 6480464 | CTD | Asbestos, Amosite results in increased expression of TNF protein | PMID:27083413 | Tnf | increases expression | ISO | TNF (Homo sapiens) | 6480464 | CTD | Asbestos, Amosite results in increased expression of TNF mRNA | PMID:8473757 | Tnf | increases secretion | ISO | TNF (Homo sapiens) | 6480464 | CTD | Asbestos, Amosite results in increased secretion of TNF protein | PMID:8473757 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | [Asbestos, Amosite co-treated with TNF protein] results in increased activity of SOD2 protein; [Asbestos, Amosite co-treated with TNF protein] results in increased expression of SOD2 mRNA; [Asbestos, Amosite co-treated with TNF protein] results in increased metabolism of Adenosine Triphosphate; [Asbestos, Amosite co-treated with TNF protein] results in increased susceptibility to Vitamin K 3; Vitamin K 3 promotes the reaction [[Asbestos, Amosite co-treated with TNF protein] results in increased metabolism of Adenosine Triphosphate] | PMID:8817062 | | ||||||||||||||||||||||
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