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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3876
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnf
Name: tumor necrosis factor
Acc ID: CHEBI:28216
Term: methylmercury chloride
Definition: A chlorine molecular entity that has formula CH3ClHg.
Chemical ID: MESH:C004925
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tnfincreases expressionEXP 6480464CTDmethylmercuric chloride results in increased expression of TNF proteinPMID:28526320 PMID:34062221
Tnfmultiple interactionsEXP 6480464CTDBee Venoms inhibits the reaction [methylmercuric chloride results in increased expression of TNF protein]PMID:34062221
Tnfincreases expressionISOTNF (Homo sapiens)6480464CTDmethylmercuric chloride results in increased expression of TNF mRNAPMID:31878059
Tnfmultiple interactionsISOTNF (Homo sapiens)6480464CTDHOXB13 protein affects the reaction [methylmercuric chloride results in increased expression of TNF mRNA]; NEXN-AS1 protein affects the reaction [methylmercuric chloride results in increased expression of TNF mRNA]PMID:31878059
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