An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID:
MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Doxorubicin results in increased expression of TNF; Doxorubicin results in increased expression of TNF mRNA; Doxorubicin results in increased expression of TNF protein
Acetylcysteine promotes the reaction [Doxorubicin results in increased expression of TNF mRNA]; allyl isothiocyanate inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Amiloride inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Carvedilol inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; caryophyllene inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; celastrol inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; certoparin inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; corilagin inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; crocin inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Curcumin inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Dalteparin affects the reaction [Doxorubicin affects the expression of TNF protein]; dioscin inhibits the reaction [Doxorubicin results in increased expression of TNF mRNA]; Ellagic Acid inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Exenatide inhibits the reaction [Doxorubicin results in increased expression of TNF mRNA]; Exenatide inhibits the reaction [Doxorubicin results in increased secretion of TNF protein]; Febuxostat inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of TNF protein]]; galangin inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; geraniol inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; GHRL protein inhibits the reaction [Doxorubicin results in decreased expression of TNF protein]; iodopravadoline inhibits the reaction [caryophyllene inhibits the reaction [Doxorubicin results in increased expression of TNF protein]]; Metformin inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; morin inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Nicorandil inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; NR1H4 protein affects the reaction [dioscin inhibits the reaction [Doxorubicin results in increased expression of TNF mRNA]]; pimagedine inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of TNF protein]]; Proanthocyanidins inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Propolis inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Quercetin inhibits the reaction [Doxorubicin results in increased expression of TNF mRNA]; Quercetin inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Ramipril inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Resveratrol inhibits the reaction [Doxorubicin results in increased expression of TNF]; Rosmarinic Acid inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Sitagliptin Phosphate inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Tannic Acid inhibits the reaction [Doxorubicin results in increased expression of TNF mRNA]; thymoquinone inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; TNF protein affects the reaction [GHRL protein inhibits the reaction [Doxorubicin results in decreased expression of BCL2 mRNA]]; TNF protein affects the reaction [GHRL protein inhibits the reaction [Doxorubicin results in decreased expression of BCL2L1 mRNA]]; TNF protein promotes the reaction [Doxorubicin results in increased cleavage of and results in increased activity of CASP3 protein]; TNF protein promotes the reaction [Doxorubicin results in increased cleavage of and results in increased activity of CASP8 protein]; TNF protein promotes the reaction [Doxorubicin results in increased cleavage of PARP1 protein]; Trimetazidine inhibits the reaction [Doxorubicin results in increased expression of TNF protein]
[Vancomycin co-treated with Neomycin co-treated with Cilastatin, Imipenem Drug Combination] inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; [Vancomycin co-treated with Neomycin co-treated with Cilastatin, Imipenem Drug Combination] inhibits the reaction [Nanotubes, Carbon promotes the reaction [Doxorubicin results in increased expression of TNF protein]]; Bosentan inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; CDKN1A gene mutant form inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; cibinetide inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Doxorubicin results in increased expression of and results in increased secretion of TNF protein; epalrestat analog inhibits the reaction [Doxorubicin results in increased expression of and results in increased secretion of TNF protein]; epalrestat analog inhibits the reaction [Doxorubicin results in increased secretion of TNF protein]; epalrestat inhibits the reaction [Doxorubicin results in increased secretion of TNF protein]; Exenatide inhibits the reaction [Doxorubicin results in increased expression of TNF mRNA]; Genistein inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; IFNG gene mutant form inhibits the reaction [TNF protein modified form results in increased susceptibility to Doxorubicin]; IL1B protein promotes the reaction [[Doxorubicin co-treated with Nanotubes, Carbon] results in increased expression of TNF protein]; indole-3-carbinol inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Lovastatin inhibits the reaction [Doxorubicin results in increased expression of TNF mRNA]; Meloxicam inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Nanotubes, Carbon promotes the reaction [Doxorubicin results in increased expression of TNF protein]; naringin inhibits the reaction [Doxorubicin results in increased expression of TNF mRNA]; Niclosamide inhibits the reaction [Doxorubicin results in increased expression of TNF mRNA]; tetrathiomolybdate inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; TLR2 gene mutant form inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; TNF protein promotes the reaction [[Doxorubicin co-treated with Nanotubes, Carbon] results in increased expression of CXCL9 mRNA]; TNF protein promotes the reaction [[Doxorubicin co-treated with Nanotubes, Carbon] results in increased expression of IL1B protein]; TNF protein promotes the reaction [[Doxorubicin co-treated with Nanotubes, Carbon] results in increased expression of NOS2 mRNA]
[Doxorubicin co-treated with TNF protein] results in increased activity of CDK2 protein; CDKN1A protein results in decreased susceptibility to [Doxorubicin co-treated with TNF protein]; cibinetide inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Doxorubicin inhibits the reaction [TNF protein results in increased acetylation of RELA protein]; Doxorubicin inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; Doxorubicin results in increased expression of and results in increased secretion of TNF protein; TNF protein inhibits the reaction [Doxorubicin results in decreased expression of BIRC3 mRNA]; TNF protein inhibits the reaction [Doxorubicin results in decreased expression of CXCL8 mRNA]; TNF protein inhibits the reaction [Doxorubicin results in decreased expression of NFKBIA mRNA]; TNF protein inhibits the reaction [Doxorubicin results in increased expression of CDKN1A protein]; TNF protein inhibits the reaction [TP53 gene mutant form results in decreased susceptibility to Doxorubicin]; TNF protein promotes the reaction [Doxorubicin results in increased expression of CAT protein]; TNF protein promotes the reaction [Doxorubicin results in increased expression of SOD1 protein]; TNF protein promotes the reaction [Doxorubicin results in increased expression of SOD2 protein]
