GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | increases expression | EXP | | 6480464 | CTD | decabromobiphenyl ether results in increased expression of TNF mRNA | PMID:23640034 PMID:36566971 | Tnf | increases secretion | EXP | | 6480464 | CTD | decabromobiphenyl ether results in increased secretion of TNF protein | PMID:36566971 | Tnf | multiple interactions | EXP | | 6480464 | CTD | Melatonin inhibits the reaction [decabromobiphenyl ether results in increased expression of TNF mRNA]; Melatonin inhibits the reaction [decabromobiphenyl ether results in increased expression of TNF protein] | PMID:36566971 | Tnf | increases expression | ISO | Tnf (Mus musculus) | 6480464 | CTD | decabromobiphenyl ether results in increased expression of TNF protein | PMID:30836164 | Tnf | increases expression | ISO | TNF (Homo sapiens) | 6480464 | CTD | decabromobiphenyl ether results in increased expression of TNF protein | PMID:33675858 | Tnf | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | [lead chloride results in increased abundance of Lead] promotes the reaction [decabromobiphenyl ether results in increased expression of TNF protein]; decabromobiphenyl ether promotes the reaction [[lead chloride results in increased abundance of Lead] which results in increased expression of TNF protein] | PMID:30836164 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | Luteolin inhibits the reaction [decabromobiphenyl ether results in increased expression of TNF protein] | PMID:33675858 | |
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