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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:peptide and protein hormone signaling pathway
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Accession:PW:0000467 term browser browse the term

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peptide and protein hormone signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LHCGR luteinizing hormone/choriogonadotropin receptor ISO luteinizing hormone/chorionic gonadotropin RGD PMID:2502842 RGD:1566529 NCBI chr14:58,413,334...58,479,124
Ensembl chr14:58,413,993...58,477,987 		JBrowse link
adiponectin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO RGD PMID:16823476 RGD:1642395 NCBI chr15:81,128,427...81,142,779
Ensembl chr15:81,129,795...81,147,391 		JBrowse link
G ADIPOR1 adiponectin receptor 1 ISO RGD PMID:16823476 RGD:1642395 NCBI chr25:26,445,993...26,462,346
Ensembl chr25:26,453,242...26,462,549 		JBrowse link
G ADIPOR2 adiponectin receptor 2 ISO RGD PMID:16823476 PMID:18755807 PMID:24797033 PMID:27220557 RGD:1642395 RGD:25824939 RGD:25824940 RGD:25824943 NCBI chr11:1,802,694...1,836,703
Ensembl chr11:1,738,026...1,837,060 		JBrowse link
altered insulin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INS insulin ISO RGD PMID:9809695 RGD:2313694 NCBI chr 1:1,965,128...1,969,090 JBrowse link
G INSR insulin receptor ISO RGD PMID:9809695 RGD:2313694 NCBI chr 6:6,625,951...6,803,610
Ensembl chr 6:6,630,777...6,803,592 		JBrowse link
altered insulin-like growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IGF1 insulin like growth factor 1 ISO RGD PMID:15996002 RGD:1580474 NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308 		JBrowse link
altered leptin system pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INSR insulin receptor ISO increased basal hypothalamic leptin signaling without changes in leptin receptor expression after antisense-mediated hypothalamus-specific Insr knock-down RGD PMID:17585961 RGD:2290473 NCBI chr 6:6,625,951...6,803,610
Ensembl chr 6:6,630,777...6,803,592 		JBrowse link
G LEP leptin ISO RGD PMID:11102451 PMID:15703762 RGD:1357910 RGD:61790 NCBI chr21:97,056,913...97,071,161
Ensembl chr21:97,057,529...97,071,220 		JBrowse link
G LEPR leptin receptor ISO RGD PMID:11102451 PMID:15703762 PMID:17229951 RGD:1357910 RGD:1600611 RGD:61790 NCBI chr20:67,454,205...67,567,524
Ensembl chr20:67,454,334...67,524,229 		JBrowse link
altered melanocortin system pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGRP agouti related neuropeptide ISO RGD PMID:15189116 RGD:1357925 NCBI chr 5:59,972,728...59,974,728
Ensembl chr 5:59,973,922...59,974,660 		JBrowse link
G MC4R melanocortin 4 receptor ISO RGD PMID:15189116 RGD:1357925 NCBI chr18:19,380,054...19,386,412
Ensembl chr18:19,380,849...19,381,847 		JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 ISO RGD PMID:11874690 PMID:15189116 RGD:1357925 RGD:1357926 NCBI chr 4:90,246,413...90,289,148
Ensembl chr 4:90,248,598...90,289,089 		JBrowse link
G POMC proopiomelanocortin ISO RGD PMID:11874690 PMID:15189116 RGD:1357925 RGD:1357926 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G SDC1 syndecan 1 ISO RGD PMID:15189116 RGD:1357925 NCBI chr14:87,499,732...87,523,122
Ensembl chr14:87,499,574...87,525,026 		JBrowse link
angiotensin (1-7) signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE2 angiotensin converting enzyme 2 ISO RGD PMID:15638741 RGD:1581742 NCBI chr  X:14,032,231...14,094,163
Ensembl chr  X:14,030,233...14,077,785 		JBrowse link
G AGT angiotensinogen ISO RGD PMID:15951342 RGD:1581938 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G MAS1 MAS1 proto-oncogene, G protein-coupled receptor ISO RGD PMID:15951342 PMID:16520407 RGD:1581931 RGD:1581938 NCBI chr13:87,520,860...87,523,523
Ensembl chr13:87,521,947...87,523,098 		JBrowse link
G MME membrane metalloendopeptidase ISO RGD PMID:10642323 PMID:15638741 PMID:16520407 RGD:1581742 RGD:1581931 RGD:1581953 NCBI chr15:35,577,460...35,681,730
Ensembl chr15:35,580,714...35,633,914 		JBrowse link
angiotensin II signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:16141358 RGD:1581847 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:15590154 RGD:1579760 NCBI chr15:41,957,826...42,002,776 JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:14657020 RGD:1566502
G CCL2 C-C motif chemokine ligand 2 ISO RGD PMID:14684844 RGD:1582323 NCBI chr16:27,763,354...27,765,437
Ensembl chr16:27,763,555...27,765,416 		JBrowse link
G CMA1 chymase 1 ISO RGD PMID:15638741 PMID:15869764 RGD:1581742 RGD:1581745 NCBI chr24:1,471,767...1,475,062
Ensembl chr24:1,471,725...1,474,692 		JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:16269269 RGD:1600094 NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710 		JBrowse link
G OLR1 oxidized low density lipoprotein receptor 1 ISO RGD PMID:12661921 RGD:1580992 NCBI chr11:10,033,708...10,048,332
Ensembl chr11:10,033,635...10,048,256 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 ISO RGD PMID:14585963 RGD:1581775
G PLA2G6 phospholipase A2 group VI ISO RGD PMID:17613534 RGD:12910844 NCBI chr19:20,818,575...20,884,243 JBrowse link
G PRKCZ protein kinase C zeta ISO RGD PMID:16113073 RGD:1642674 NCBI chr20:129,367,309...129,502,681
Ensembl chr20:129,365,679...129,485,818 		JBrowse link
angiotensin II signaling pathway via AT1 receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:16141358 RGD:1581847 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:9287353 PMID:10977869 PMID:12446719 PMID:14559250 RGD:1581825 RGD:2316188 RGD:5133683 RGD:629553 NCBI chr15:41,957,826...42,002,776 JBrowse link
G AGTRAP angiotensin II receptor associated protein ISO RGD PMID:17875818 RGD:2314353 NCBI chr20:120,041,804...120,056,597
Ensembl chr20:120,041,479...120,056,557 		JBrowse link
G ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 ISO RGD PMID:14559250 RGD:2316188 NCBI chr 1:63,923,241...63,991,221
Ensembl chr 1:63,920,076...63,960,771 		JBrowse link
G ARRB1 arrestin beta 1 ISO RGD PMID:16304060 RGD:5133417 NCBI chr 1:66,489,358...66,580,167
Ensembl chr 1:66,490,102...66,580,154 		JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:16304060 RGD:5133417 NCBI chr16:4,191,040...4,202,382
Ensembl chr16:4,191,172...4,202,385 		JBrowse link
G GNA11 G protein subunit alpha 11 ISO RGD PMID:16141358 RGD:1581847 NCBI chr 6:2,858,880...2,887,694
Ensembl chr 6:2,858,937...2,887,704 		JBrowse link
G GNAQ G protein subunit alpha q ISO RGD PMID:16141358 RGD:1581847 NCBI chr12:88,666,375...88,988,989
Ensembl chr12:88,670,424...88,871,154 		JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:16304060 RGD:5133417 NCBI chr 1:6,975,202...6,995,369
Ensembl chr 1:6,975,002...6,995,259 		JBrowse link
G GRK3 G protein-coupled receptor kinase 3 ISO RGD PMID:16304060 RGD:5133417 NCBI chr19:8,438,543...8,601,652
Ensembl chr19:8,438,380...8,600,359 		JBrowse link
G GRK5 G protein-coupled receptor kinase 5 ISO RGD PMID:16304060 RGD:5133417 NCBI chr 9:111,996,780...112,249,247
Ensembl chr 9:111,996,599...112,244,570 		JBrowse link
G GRK6 G protein-coupled receptor kinase 6 ISO RGD PMID:16304060 RGD:5133417 NCBI chr23:79,437,056...79,454,213
Ensembl chr23:79,437,078...79,453,113 		JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:9287353 PMID:9314843 RGD:5133683 RGD:6478796 NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710 		JBrowse link
G RGS2 regulator of G protein signaling 2 ISO RGD PMID:12588881 RGD:5133418 NCBI chr25:36,620,047...36,623,367
Ensembl chr25:36,619,140...36,623,308 		JBrowse link
G TYK2 tyrosine kinase 2 ISO RGD PMID:9314843 RGD:6478796 NCBI chr 6:9,399,945...9,420,054
Ensembl chr 6:9,399,775...9,417,630 		JBrowse link
angiotensin II signaling pathway via AT2 receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:16286564 PMID:16286568 PMID:22949090 RGD:1582434 RGD:1582435 RGD:7401256 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:10977869 PMID:22949090 RGD:1581825 RGD:7401256
G CNKSR1 connector enhancer of kinase suppressor of Ras 1 ISO RGD PMID:20889352 RGD:5133679 NCBI chr20:106,577,470...106,596,544
Ensembl chr20:106,577,809...106,589,788 		JBrowse link
G DUSP1 dual specificity phosphatase 1 ISO RGD PMID:18804122 RGD:5133675 NCBI chr23:74,931,421...74,934,510
Ensembl chr23:74,929,863...74,934,532 		JBrowse link
G ERBB3 erb-b2 receptor tyrosine kinase 3 ISO RGD PMID:20889352 RGD:5133679 NCBI chr11:52,020,912...52,043,809
Ensembl chr11:52,021,058...52,044,028 		JBrowse link
G GNAI2 G protein subunit alpha i2 ISO RGD PMID:22949090 RGD:7401256 NCBI chr22:11,623,394...11,646,464
Ensembl chr22:11,623,408...11,647,191 		JBrowse link
G GNAI3 G protein subunit alpha i3 ISO RGD PMID:22949090 RGD:7401256 NCBI chr20:23,950,819...24,000,069
Ensembl chr20:23,954,384...23,999,072 		JBrowse link
G MTUS1 microtubule associated scaffold protein 1 ISO RGD PMID:20889352 RGD:5133679 NCBI chr 8:15,739,220...15,899,834
Ensembl chr 8:15,741,294...15,853,293 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 ISO RGD PMID:18804122 RGD:5133675 NCBI chr11:6,977,480...6,994,525
Ensembl chr11:6,984,710...6,994,545 		JBrowse link
G SLC9A6 solute carrier family 9 member A6 ISO RGD PMID:20889352 RGD:5133679 NCBI chr  X:110,997,985...111,060,164
Ensembl chr  X:110,998,281...111,060,252 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO RGD PMID:20889352 RGD:5133679 NCBI chr19:15,621,609...15,684,118
Ensembl chr19:15,622,431...15,680,449 		JBrowse link
G ZBTB16 zinc finger and BTB domain containing 16 ISO RGD PMID:20889352 RGD:5133679 NCBI chr 1:105,446,067...105,648,771
Ensembl chr 1:105,449,994...105,643,344 		JBrowse link
angiotensin III signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:11295571 RGD:1582124 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO RGD PMID:11295571 RGD:1582124 NCBI chr15:41,957,826...42,002,776 JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:11295571 RGD:1582124
G ENPEP glutamyl aminopeptidase ISO RGD PMID:15638741 PMID:16537183 RGD:1581649 RGD:1581742 NCBI chr 7:58,363,816...58,448,231
Ensembl chr 7:58,364,445...58,447,574 		JBrowse link
angiotensin III signaling pathway via AT1 receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:11100981 RGD:1582152 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
angiotensin III signaling pathway via AT2 receptor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:16380540 RGD:1582118 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:16380540 RGD:1582118
angiotensin IV signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:11282364 RGD:1582105 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
G ANPEP alanyl aminopeptidase, membrane ISO RGD PMID:15638741 PMID:16537183 RGD:1581649 RGD:1581742 NCBI chr29:8,324,094...8,354,491
Ensembl chr29:8,323,797...8,346,581 		JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase ISO RGD PMID:11282364 PMID:12591177 RGD:1581864 RGD:1582105 NCBI chr 4:90,769,988...90,872,205
Ensembl chr 4:90,770,272...90,863,268 		JBrowse link
G RNPEP arginyl aminopeptidase ISO RGD PMID:16537183 RGD:1581649 NCBI chr25:27,401,749...27,426,371
Ensembl chr25:27,401,757...27,426,410 		JBrowse link
angiotensin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:12676165 RGD:1566511 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324 		JBrowse link
apelin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APLN apelin ISO RGD PMID:14645236 RGD:1304466 NCBI chr  X:104,885,639...104,896,371
Ensembl chr  X:104,888,996...104,895,014 		JBrowse link
G APLNR apelin receptor ISO RGD PMID:14645236 RGD:1304466 NCBI chr 1:16,007,092...16,011,868
Ensembl chr 1:16,008,300...16,009,601 		JBrowse link
atrial natriuretic peptide signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CORIN corin, serine peptidase ISO RGD PMID:17485366 RGD:1626338 NCBI chr27:2,407,451...2,662,855
Ensembl chr27:2,408,219...2,662,279 		JBrowse link
G NPPA natriuretic peptide A ISO RGD PMID:12608696 PMID:15758553 PMID:16010968 RGD:1578335 RGD:1580001 RGD:1626242 NCBI chr20:119,942,412...119,946,211
Ensembl chr20:119,944,532...119,945,917 		JBrowse link
G NPR1 natriuretic peptide receptor 1 ISO RGD PMID:7552344 RGD:1626243 NCBI chr20:10,115,319...10,131,933
Ensembl chr20:10,115,105...10,131,200 		JBrowse link
brain natriuretic peptide signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPPB natriuretic peptide B ISO RGD PMID:7552344 RGD:1626243 NCBI chr20:119,930,931...119,933,391
Ensembl chr20:119,932,021...119,933,197 		JBrowse link
G NPR1 natriuretic peptide receptor 1 ISO RGD PMID:7552344 RGD:1626243 NCBI chr20:10,115,319...10,131,933
Ensembl chr20:10,115,105...10,131,200 		JBrowse link
C-type natriuretic peptide signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPPC natriuretic peptide C ISO RGD PMID:15337698 PMID:16537417 RGD:1580149 RGD:1601488 NCBI chr10:117,919,889...117,924,306
Ensembl chr10:117,919,760...117,924,273 		JBrowse link
G NPR2 natriuretic peptide receptor 2 ISO RGD PMID:16537417 RGD:1601488 NCBI chr12:44,795,822...44,844,464
Ensembl chr12:44,793,253...44,813,671 		JBrowse link
G NPR3 natriuretic peptide receptor 3 ISO RGD PMID:15044621 RGD:1581459 NCBI chr 4:31,984,712...32,062,593
Ensembl chr 4:31,986,217...32,062,199 		JBrowse link
corticotropin-releasing hormone signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB1 arrestin beta 1 ISO RGD PMID:16918397 RGD:5147673 NCBI chr 1:66,489,358...66,580,167
Ensembl chr 1:66,490,102...66,580,154 		JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:16918397 RGD:5147673 NCBI chr16:4,191,040...4,202,382
Ensembl chr16:4,191,172...4,202,385 		JBrowse link
G CRH corticotropin releasing hormone ISO RGD PMID:12942143 PMID:16484629 RGD:1358326 RGD:5147387 NCBI chr 8:62,052,155...62,056,424
Ensembl chr 8:62,052,592...62,053,182 		JBrowse link
G CRHBP corticotropin releasing hormone binding protein ISO RGD PMID:16484629 RGD:5147387 NCBI chr 4:71,203,335...71,223,179
Ensembl chr 4:71,205,932...71,223,172 		JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:12942143 PMID:16484629 RGD:1358326 RGD:5147387 NCBI chr21:27,703,637...27,738,873
Ensembl chr21:27,708,113...27,739,116 		JBrowse link
G GRK3 G protein-coupled receptor kinase 3 ISO RGD PMID:16484629 RGD:5147387 NCBI chr19:8,438,543...8,601,652
Ensembl chr19:8,438,380...8,600,359 		JBrowse link
G GRK6 G protein-coupled receptor kinase 6 ISO RGD PMID:16484629 RGD:5147387 NCBI chr23:79,437,056...79,454,213
Ensembl chr23:79,437,078...79,453,113 		JBrowse link
G LOC103243260 corticotropin-releasing factor receptor 1 ISO RGD PMID:12942143 PMID:16484629 RGD:1358326 RGD:5147387 NCBI chr16:60,070,156...60,120,857
Ensembl chr16:60,070,066...60,120,712 		JBrowse link
G LOC103243509 neuroendocrine secretory protein 55 ISO RGD PMID:16484629 RGD:5147387 NCBI chr 2:5,233,893...5,303,433
Ensembl chr 2:5,233,874...5,249,192 		JBrowse link
G UCN urocortin ISO RGD PMID:16484629 RGD:5147387 NCBI chr14:80,303,210...80,304,910
Ensembl chr14:80,304,416...80,304,790 		JBrowse link
G UCN2 urocortin 2 ISO RGD PMID:16484629 RGD:5147387 NCBI chr22:9,962,339...9,964,553 JBrowse link
G UCN3 urocortin 3 ISO RGD PMID:16484629 RGD:5147387 NCBI chr 9:5,491,134...5,500,663
Ensembl chr 9:5,498,945...5,499,430 		JBrowse link
endothelin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY1 adenylate cyclase 1 ISO PID PID:200005 NCBI chr21:12,976,687...13,117,876
Ensembl chr21:12,979,033...13,117,730 		JBrowse link
G ADCY2 adenylate cyclase 2 ISO PID PID:200005 NCBI chr 4:6,989,077...7,415,282
Ensembl chr 4:6,989,169...7,414,617 		JBrowse link
G ADCY3 adenylate cyclase 3 ISO PID PID:200005 NCBI chr14:82,752,786...82,858,727
Ensembl chr14:82,753,177...82,859,415 		JBrowse link
G ADCY4 adenylate cyclase 4 ISO PID PID:200005 NCBI chr24:1,301,445...1,318,171
Ensembl chr24:1,301,506...1,316,868 		JBrowse link
G ADCY5 adenylate cyclase 5 ISO PID PID:200005 NCBI chr22:57,427,711...57,589,440 JBrowse link
G ADCY6 adenylate cyclase 6 ISO PID PID:200005 NCBI chr11:45,006,220...45,031,481
Ensembl chr11:45,005,637...45,025,501 		JBrowse link
G ADCY7 adenylate cyclase 7 ISO PID PID:200005 NCBI chr 5:36,086,680...36,122,021
Ensembl chr 5:36,065,319...36,113,921 		JBrowse link
G ADCY8 adenylate cyclase 8 ISO PID PID:200005 NCBI chr 8:125,269,396...125,535,806
Ensembl chr 8:125,269,736...125,533,015 		JBrowse link
G ADCY9 adenylate cyclase 9 ISO PID PID:200005 NCBI chr 5:3,641,359...3,796,697
Ensembl chr 5:3,641,349...3,796,198 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO PID PID:200005 NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698 		JBrowse link
G BCAR1 BCAR1 scaffold protein, Cas family member ISO PID PID:200005 NCBI chr 5:60,709,409...60,749,071
Ensembl chr 5:60,707,006...60,732,882 		JBrowse link
G CDC42 cell division cycle 42 ISO PID PID:200005 NCBI chr20:110,568,004...110,608,318
Ensembl chr20:110,569,352...110,582,562 		JBrowse link
G COL1A2 collagen type I alpha 2 chain ISO PID PID:200005 NCBI chr21:54,602,780...54,639,832
Ensembl chr21:54,602,398...54,632,780 		JBrowse link
G COL3A1 collagen type III alpha 1 chain ISO PID PID:200005 NCBI chr10:74,455,133...74,493,392 JBrowse link
G CRK CRK proto-oncogene, adaptor protein ISO PID PID:200005 NCBI chr16:1,102,485...1,135,225
Ensembl chr16:1,102,348...1,135,166 		JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 ISO PID PID:200005
G CYSLTR2 cysteinyl leukotriene receptor 2 ISO PID PID:200005 NCBI chr 3:26,578,248...26,624,364 JBrowse link
G ECE1 endothelin converting enzyme 1 ISO RGD PMID:15733912 RGD:1581735 NCBI chr20:111,212,567...111,342,755
Ensembl chr20:111,212,594...111,342,821 		JBrowse link
G EDN1 endothelin 1 ISO RGD
PID		 PMID:15124920 PID:200005 RGD:1580323 NCBI chr17:59,854,186...59,861,319
Ensembl chr17:59,853,699...59,861,198 		JBrowse link
G EDN2 endothelin 2 ISO PID PID:200005 NCBI chr20:91,425,979...91,432,609
Ensembl chr20:91,426,747...91,431,973 		JBrowse link
G EDN3 endothelin 3 ISO PID PID:200005 NCBI chr 2:4,814,447...4,839,950
Ensembl chr 2:4,814,140...4,839,626 		JBrowse link
G EDNRA endothelin receptor type A ISO PID
RGD		 PMID:20409845 PID:200005 RGD:4892591 NCBI chr 7:93,980,983...94,043,863
Ensembl chr 7:93,985,797...94,042,296 		JBrowse link
G EDNRB endothelin receptor type B ISO RGD
PID		 PMID:20409845 PID:200005 RGD:4892591 NCBI chr 3:56,969,493...56,993,719
Ensembl chr 3:56,969,101...56,992,731 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO PID PID:200005 NCBI chr24:52,497,465...52,501,161
Ensembl chr24:52,497,521...52,501,514 		JBrowse link
G GNA11 G protein subunit alpha 11 ISO PID PID:200005 NCBI chr 6:2,858,880...2,887,694
Ensembl chr 6:2,858,937...2,887,704 		JBrowse link
G GNA12 G protein subunit alpha 12 ISO PID PID:200005 NCBI chr28:18,778,768...18,890,420
Ensembl chr28:18,778,847...18,888,922 		JBrowse link
G GNA14 G protein subunit alpha 14 ISO PID PID:200005 NCBI chr12:88,386,597...88,606,787
Ensembl chr12:88,385,377...88,605,845 		JBrowse link
G GNA15 G protein subunit alpha 15 ISO PID PID:200005 NCBI chr 6:2,901,502...2,930,567
Ensembl chr 6:2,901,762...2,932,138 		JBrowse link
G GNAI1 G protein subunit alpha i1 ISO PID PID:200005 NCBI chr21:68,687,809...68,770,415
Ensembl chr21:68,687,307...68,770,360 		JBrowse link
G GNAI2 G protein subunit alpha i2 ISO PID PID:200005 NCBI chr22:11,623,394...11,646,464
Ensembl chr22:11,623,408...11,647,191 		JBrowse link
G GNAI3 G protein subunit alpha i3 ISO PID PID:200005 NCBI chr20:23,950,819...24,000,069
Ensembl chr20:23,954,384...23,999,072 		JBrowse link
G GNAL G protein subunit alpha L ISO PID PID:200005 NCBI chr18:69,508,254...69,699,628
Ensembl chr18:69,510,512...69,635,000 		JBrowse link
G GNAO1 G protein subunit alpha o1 ISO PID PID:200005 NCBI chr 5:42,105,295...42,272,573
Ensembl chr 5:42,105,334...42,273,059 		JBrowse link
G GNAQ G protein subunit alpha q ISO PID PID:200005 NCBI chr12:88,666,375...88,988,989
Ensembl chr12:88,670,424...88,871,154 		JBrowse link
G GNAZ G protein subunit alpha z ISO PID PID:200005 NCBI chr19:2,758,097...2,812,306
Ensembl chr19:2,757,819...2,788,076 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO PID PID:200005 NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637 		JBrowse link
G JAK2 Janus kinase 2 ISO PID PID:200005 NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO PID PID:200005 NCBI chr20:74,204,481...74,207,835
Ensembl chr20:74,205,542...74,206,546 		JBrowse link
G LOC103214902 sodium/hydrogen exchanger 3 ISO PID PID:200005 NCBI chr 4:362,417...408,113
Ensembl chr 4:365,135...408,033 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 ISO PID PID:200005 NCBI chr26:17,059,122...17,168,787
Ensembl chr26:17,060,054...17,168,782 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 ISO PID PID:200005 NCBI chr 6:3,848,441...3,881,367
Ensembl chr 6:3,848,401...3,881,412 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO PID PID:200005 NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 ISO PID PID:200005 NCBI chr17:36,012,164...36,095,542
Ensembl chr17:36,014,454...36,095,138 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 ISO PID PID:200005 NCBI chr 5:26,536,471...26,545,666
Ensembl chr 5:26,536,532...26,546,461 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO PID PID:200005 NCBI chr 9:43,356,603...43,489,066
Ensembl chr 9:43,356,308...43,393,425 		JBrowse link
G MMP1 matrix metallopeptidase 1 ISO PID PID:200005 NCBI chr 1:94,167,507...94,177,357
Ensembl chr 1:94,167,219...94,176,767 		JBrowse link
G NFATC3 nuclear factor of activated T cells 3 ISO RGD PMID:15016802 RGD:1581961 NCBI chr 5:59,193,139...59,346,361 JBrowse link
G NOS2 nitric oxide synthase 2 ISO RGD PMID:16552365 RGD:1582119 NCBI chr16:21,533,011...21,576,645
Ensembl chr16:21,533,484...21,574,257 		JBrowse link
G PLA2G4A phospholipase A2 group IVA ISO PID PID:200005 NCBI chr25:42,443,480...42,590,895
Ensembl chr25:42,443,385...42,590,431 		JBrowse link
G PLCB1 phospholipase C beta 1 ISO PID PID:200005 NCBI chr 2:29,242,601...29,994,238
Ensembl chr 2:29,242,425...29,496,793 		JBrowse link
G PLCB2 phospholipase C beta 2 ISO PID PID:200005 NCBI chr26:42,706,462...42,727,516
Ensembl chr26:42,707,625...42,727,145 		JBrowse link
G PLCB3 phospholipase C beta 3 ISO PID PID:200005 NCBI chr 1:9,964,850...9,982,573
Ensembl chr 1:9,966,618...9,982,317 		JBrowse link
G PRKCA protein kinase C alpha ISO PID PID:200005 NCBI chr16:54,638,548...55,144,372
Ensembl chr16:54,642,729...54,948,256 		JBrowse link
G PRKCD protein kinase C delta ISO PID PID:200005 NCBI chr22:14,561,401...14,592,877
Ensembl chr22:14,565,282...14,592,873 		JBrowse link
G PRKCE protein kinase C epsilon ISO PID PID:200005 NCBI chr14:61,022,903...61,570,390
Ensembl chr14:61,026,017...61,242,343 		JBrowse link
G PRKCG protein kinase C gamma ISO PID PID:200005 NCBI chr 6:46,574,560...46,600,329
Ensembl chr 6:46,575,439...46,600,364 		JBrowse link
G PRKCH protein kinase C eta ISO PID PID:200005 NCBI chr24:38,489,535...38,726,028
Ensembl chr24:38,488,970...38,724,879 		JBrowse link
G PRKCQ protein kinase C theta ISO PID PID:200005 NCBI chr 9:6,532,438...6,675,708
Ensembl chr 9:6,532,319...6,621,487 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta ISO PID PID:200005 NCBI chr 8:25,437,680...25,571,594
Ensembl chr 8:25,437,564...25,571,782 		JBrowse link
G RAC1 Rac family small GTPase 1 ISO PID PID:200005 NCBI chr28:15,583,609...15,610,753
Ensembl chr28:15,583,516...15,610,328 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase ISO PID PID:200005 NCBI chr22:48,560,270...48,643,537
Ensembl chr22:48,561,161...48,618,020 		JBrowse link
G RHOA ras homolog family member A ISO PID PID:200005 NCBI chr22:10,757,381...10,809,257
Ensembl chr22:10,757,337...10,772,704 		JBrowse link
G SLC9A1 solute carrier family 9 member A1 ISO PID PID:200005 NCBI chr20:105,613,289...105,670,868
Ensembl chr20:105,613,338...105,674,208 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO PID PID:200005 NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776 		JBrowse link
G TRPC6 transient receptor potential cation channel subfamily C member 6 ISO PID PID:200005 NCBI chr 1:92,828,546...92,970,224
Ensembl chr 1:92,829,253...92,885,086 		JBrowse link
erythropoietin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator ISO PID PID:200183 NCBI chr18:16,440,560...16,643,187
Ensembl chr18:16,441,733...16,637,895 		JBrowse link
G BCL2L1 BCL2 like 1 ISO PID PID:200183 NCBI chr 2:36,059,024...36,118,332
Ensembl chr 2:36,058,919...36,116,470 		JBrowse link
G BTK Bruton tyrosine kinase ISO PID PID:200183 NCBI chr  X:89,690,569...89,727,420 JBrowse link
G CBL Cbl proto-oncogene ISO PID PID:200183 NCBI chr 1:110,581,049...110,679,284
Ensembl chr 1:110,581,143...110,674,481 		JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein ISO PID PID:200183
G EPO erythropoietin ISO PID PID:200183 NCBI chr28:12,487,222...12,491,986
Ensembl chr28:12,489,766...12,491,908 		JBrowse link
G EPOR erythropoietin receptor ISO PID PID:200183 NCBI chr 6:10,313,382...10,320,196
Ensembl chr 6:10,313,775...10,320,066 		JBrowse link
G GAB1 GRB2 associated binding protein 1 ISO PID PID:200183 NCBI chr 7:90,197,374...90,323,024
Ensembl chr 7:90,197,620...90,322,077 		JBrowse link
G GRB2 growth factor receptor bound protein 2 ISO PID PID:200183 NCBI chr16:46,264,818...46,346,426
Ensembl chr16:46,264,825...46,347,156 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO PID PID:200183 NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637 		JBrowse link
G INPP5D inositol polyphosphate-5-phosphatase D ISO PID PID:200183 NCBI chr10:119,093,160...119,244,128
Ensembl chr10:119,093,781...119,244,123 		JBrowse link
G IRS2 insulin receptor substrate 2 ISO PID PID:200183 NCBI chr 3:88,045,439...88,076,468 JBrowse link
G JAK2 Janus kinase 2 ISO PID PID:200183 NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710 		JBrowse link
G LOC103243413 signal transducer and activator of transcription 5B ISO PID PID:200183 NCBI chr16:63,997,486...64,070,392
Ensembl chr16:63,997,441...64,070,445 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase ISO PID PID:200183 NCBI chr 8:51,919,656...52,057,376
Ensembl chr 8:51,919,808...52,057,959 		JBrowse link
G MAPK14 mitogen-activated protein kinase 14 ISO PID PID:200183 NCBI chr17:36,012,164...36,095,542
Ensembl chr17:36,014,454...36,095,138 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO PID PID:200183 NCBI chr 9:43,356,603...43,489,066
Ensembl chr 9:43,356,308...43,393,425 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 ISO PID PID:200183 NCBI chr 7:50,589,494...50,711,472
Ensembl chr 7:50,589,856...50,711,498 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO PID PID:200183 NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519 		JBrowse link
G PLCG1 phospholipase C gamma 1 ISO PID PID:200183 NCBI chr 2:22,599,547...22,638,394 JBrowse link
G PLCG2 phospholipase C gamma 2 ISO PID PID:200183 NCBI chr 5:67,209,268...67,394,865
Ensembl chr 5:67,215,459...67,398,990 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO PID PID:200183 NCBI chr11:107,658,495...107,754,457
Ensembl chr11:107,658,453...107,752,637 		JBrowse link
G PTPN6 protein tyrosine phosphatase non-receptor type 6 ISO PID PID:200183 NCBI chr11:6,977,480...6,994,525
Ensembl chr11:6,984,710...6,994,545 		JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISO PID PID:200183 NCBI chr20:21,895,829...21,989,008
Ensembl chr20:21,899,669...21,917,350 		JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 ISO PID PID:200183 NCBI chr12:6,407,030...6,566,200
Ensembl chr12:6,437,454...6,567,436 		JBrowse link
G SH2B3 SH2B adaptor protein 3 ISO PID PID:200183 NCBI chr11:106,657,601...106,703,940
Ensembl chr11:106,670,685...106,700,619 		JBrowse link
G SHC1 SHC adaptor protein 1 ISO PID PID:200183 NCBI chr20:8,854,189...8,866,406
Ensembl chr20:8,858,458...8,866,610 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 ISO PID PID:200183 NCBI chr16:70,353,099...70,356,401
Ensembl chr16:70,354,746...70,355,423 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO PID PID:200183 NCBI chr14:68,259,509...68,404,167
Ensembl chr14:68,259,360...68,399,895 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 ISO PID PID:200183 NCBI chr10:76,492,859...76,537,689
Ensembl chr10:76,492,533...76,533,393 		JBrowse link
G STAT5A signal transducer and activator of transcription 5A ISO PID PID:200183 NCBI chr16:63,959,265...63,986,627
Ensembl chr16:63,960,515...63,985,026 		JBrowse link
G TEC tec protein tyrosine kinase ISO PID PID:200183 NCBI chr27:1,982,549...2,118,533
Ensembl chr27:2,024,719...2,117,763 		JBrowse link
G TRPC6 transient receptor potential cation channel subfamily C member 6 ISO PID PID:200183 NCBI chr 1:92,828,546...92,970,224
Ensembl chr 1:92,829,253...92,885,086 		JBrowse link
G VAV2 vav guanine nucleotide exchange factor 2 ISO PID PID:200183 NCBI chr12:4,142,966...4,377,849
Ensembl chr12:4,143,139...4,377,852 		JBrowse link
follicle-stimulating hormone signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY2 adenylate cyclase 2 ISO SMPDB SMP:00333 NCBI chr 4:6,989,077...7,415,282
Ensembl chr 4:6,989,169...7,414,617 		JBrowse link
G CGA glycoprotein hormones, alpha polypeptide ISO SMPDB SMP:00333 NCBI chr13:11,560,543...11,578,070
Ensembl chr13:11,560,222...11,578,093 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 ISO SMPDB SMP:00333 NCBI chr10:93,316,774...93,395,187
Ensembl chr10:93,316,840...93,388,832 		JBrowse link
G ESR1 estrogen receptor 1 ISO SMPDB SMP:00333 NCBI chr13:79,153,418...79,554,552
Ensembl chr13:79,270,265...79,554,549 		JBrowse link
G FSHB follicle stimulating hormone subunit beta ISO SMPDB SMP:00333 NCBI chr 1:34,943,544...34,947,796
Ensembl chr 1:34,943,568...34,946,863 		JBrowse link
G FSHR follicle stimulating hormone receptor ISO SMPDB SMP:00333 NCBI chr14:58,013,405...58,211,528
Ensembl chr14:58,013,742...58,212,755 		JBrowse link
G GNB1 G protein subunit beta 1 ISO SMPDB SMP:00333 NCBI chr20:129,654,890...129,765,765
Ensembl chr20:129,707,085...129,766,667 		JBrowse link
G GNG12 G protein subunit gamma 12 ISO SMPDB SMP:00333 NCBI chr20:65,280,816...65,409,685
Ensembl chr20:65,403,471...65,405,699 		JBrowse link
G LOC103243509 neuroendocrine secretory protein 55 ISO SMPDB SMP:00333 NCBI chr 2:5,233,893...5,303,433
Ensembl chr 2:5,233,874...5,249,192 		JBrowse link
G MYH9 myosin heavy chain 9 ISO RGD PMID:20068007 RGD:6902910 NCBI chr19:18,985,709...19,093,304
Ensembl chr19:18,986,598...19,052,671 		JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha ISO SMPDB SMP:00333 NCBI chr 1:6,862,536...6,866,212
Ensembl chr 1:6,862,540...6,865,855 		JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00333 NCBI chr20:49,109,774...49,273,200
Ensembl chr20:49,108,425...49,178,806 		JBrowse link
ghrelin system pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRL ghrelin and obestatin prepropeptide ISO RGD PMID:15788704 RGD:1642818 NCBI chr22:46,326,458...46,332,906
Ensembl chr22:46,325,913...46,330,962 		JBrowse link
G GHSR growth hormone secretagogue receptor ISO RGD PMID:15788704 RGD:1642818 NCBI chr15:17,008,185...17,013,504
Ensembl chr15:17,009,369...17,012,618 		JBrowse link
glucagon signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY5 adenylate cyclase 5 ISO RGD PMID:10894801 PMID:17010343 RGD:2315004 RGD:2315006 NCBI chr22:57,427,711...57,589,440 JBrowse link
G ADCY6 adenylate cyclase 6 ISO RGD PMID:10894801 PMID:17010343 RGD:2315004 RGD:2315006 NCBI chr11:45,006,220...45,031,481
Ensembl chr11:45,005,637...45,025,501 		JBrowse link
G GCG glucagon ISO RGD PMID:16929363 RGD:2315015 NCBI chr10:47,550,097...47,560,610 JBrowse link
G GCGR glucagon receptor ISO RGD PMID:15687107 PMID:17010343 RGD:1625210 RGD:2315004 NCBI chr16:73,672,490...73,693,297
Ensembl chr16:73,681,571...73,693,299 		JBrowse link
G LOC103243509 neuroendocrine secretory protein 55 ISO RGD PMID:15687107 PMID:17010343 RGD:1625210 RGD:2315004 NCBI chr 2:5,233,893...5,303,433
Ensembl chr 2:5,233,874...5,249,192 		JBrowse link
growth hormone signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHR growth hormone receptor ISO See also reference RGD:1624962/PMID:11244571 RGD PMID:11064147 RGD:1624963 NCBI chr 4:41,171,038...41,464,474
Ensembl chr 4:41,285,712...41,464,666 		JBrowse link
G JAK2 Janus kinase 2 ISO See also reference RGD:1624962/PMID:11244571 RGD PMID:11064147 RGD:1624963 NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710 		JBrowse link
insulin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO PID
SMPDB		 PID:200014 SMP:00391 NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698 		JBrowse link
G AKT2 AKT serine/threonine kinase 2 ISO PID PID:200014 NCBI chr 6:34,688,585...34,740,458
Ensembl chr 6:34,690,462...34,720,781 		JBrowse link
G CAV1 caveolin 1 ISO PID PID:200014 NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627 		JBrowse link
G CBL Cbl proto-oncogene ISO PID PID:200014 NCBI chr 1:110,581,049...110,679,284
Ensembl chr 1:110,581,143...110,674,481 		JBrowse link
G DOK1 docking protein 1 ISO PID PID:200014 NCBI chr14:32,720,237...32,723,578
Ensembl chr14:32,720,026...32,723,286 		JBrowse link
G EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 ISO PID PID:200014 NCBI chr 8:36,063,311...36,092,439 JBrowse link
G ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 ISO RGD PMID:17347799 RGD:1625124 NCBI chr13:41,670,416...41,755,549 JBrowse link
G EXOC1 exocyst complex component 1 ISO PID PID:200014 NCBI chr 7:12,705,657...12,757,996
Ensembl chr 7:12,705,305...12,757,989 		JBrowse link
G EXOC2 exocyst complex component 2 ISO PID PID:200014 NCBI chr17:71,463,836...71,668,429
Ensembl chr17:71,473,962...71,670,095 		JBrowse link
G EXOC3 exocyst complex component 3 ISO PID PID:200014 NCBI chr 4:320,067...359,647
Ensembl chr 4:337,658...360,149 		JBrowse link
G EXOC4 exocyst complex component 4 ISO PID PID:200014 NCBI chr21:101,885,192...102,694,892 JBrowse link
G EXOC5 exocyst complex component 5 ISO PID PID:200014 NCBI chr24:34,388,155...34,449,832
Ensembl chr24:34,388,119...34,450,442 		JBrowse link
G EXOC6 exocyst complex component 6 ISO PID PID:200014 NCBI chr 9:85,967,316...86,310,052
Ensembl chr 9:86,097,257...86,310,049 		JBrowse link
G EXOC7 exocyst complex component 7 ISO PID PID:200014 NCBI chr16:45,568,987...45,596,676
Ensembl chr16:45,569,010...45,597,014 		JBrowse link
G F2RL2 coagulation factor II thrombin receptor like 2 ISO PID PID:200014 NCBI chr 4:70,887,979...70,895,419
Ensembl chr 4:70,886,113...70,895,113 		JBrowse link
G FOXO3 forkhead box O3 ISO PID PID:200014 NCBI chr13:65,175,764...65,303,107
Ensembl chr13:65,195,376...65,301,725 		JBrowse link
G GRB10 growth factor receptor bound protein 10 ISO PID
RGD		 PMID:17347799 PID:200014 RGD:1625124 NCBI chr21:8,022,483...8,225,339
Ensembl chr21:8,063,238...8,225,664 		JBrowse link
G GRB14 growth factor receptor bound protein 14 ISO RGD
PID		 PMID:9748281 PMID:17347799 PID:200014 RGD:1625124 RGD:61620 NCBI chr10:49,952,835...50,085,274
Ensembl chr10:49,953,059...50,084,869 		JBrowse link
G GRB2 growth factor receptor bound protein 2 ISO RGD
PID
SMPDB		 PMID:12891559 PID:200014 RGD:1299201 SMP:00391 NCBI chr16:46,264,818...46,346,426
Ensembl chr16:46,264,825...46,347,156 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO PID
SMPDB		 PID:200014 SMP:00391 NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637 		JBrowse link
G INPP5D inositol polyphosphate-5-phosphatase D ISO PID PID:200014 NCBI chr10:119,093,160...119,244,128
Ensembl chr10:119,093,781...119,244,123 		JBrowse link
G INS insulin ISO RGD
PID
SMPDB		 PMID:17347799 PID:200014 RGD:1625124 SMP:00391 NCBI chr 1:1,965,128...1,969,090 JBrowse link
G INSR insulin receptor ISO SMPDB
PID
RGD		 PMID:12850498 PMID:12891559 PMID:17347799 PMID:29896241 PID:200014 RGD:1299201 RGD:14700925 RGD:1580595 RGD:1625124 SMP:00391 NCBI chr 6:6,625,951...6,803,610
Ensembl chr 6:6,630,777...6,803,592 		JBrowse link
G IRS1 insulin receptor substrate 1 ISO SMPDB
PID
RGD		 PMID:12850498 PMID:16445997 PMID:23055040 PID:200014 RGD:1580595 RGD:1581310 RGD:7248547 SMP:00391 NCBI chr10:112,748,283...112,812,368 JBrowse link
G IRS2 insulin receptor substrate 2 ISO SMPDB
RGD		 PMID:12850498 PMID:12891559 PMID:23055040 RGD:1299201 RGD:1580595 RGD:7248547 SMP:00391 NCBI chr 3:88,045,439...88,076,468 JBrowse link
G IRS4 insulin receptor substrate 4 ISO RGD PMID:23055040 RGD:7248547 NCBI chr  X:96,589,292...96,605,715
Ensembl chr  X:96,601,944...96,605,699 		JBrowse link
G MAP2K1 mitogen-activated protein kinase kinase 1 ISO SMPDB SMP:00391 NCBI chr26:17,059,122...17,168,787
Ensembl chr26:17,060,054...17,168,782 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 ISO SMPDB SMP:00391 NCBI chr 6:3,848,441...3,881,367
Ensembl chr 6:3,848,401...3,881,412 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 ISO SMPDB SMP:00391 NCBI chr19:4,246,144...4,352,648
Ensembl chr19:4,246,122...4,353,325 		JBrowse link
G NCK1 NCK adaptor protein 1 ISO PID PID:200014 NCBI chr15:53,501,152...53,595,500
Ensembl chr15:53,500,623...53,523,576 		JBrowse link
G NCK2 NCK adaptor protein 2 ISO PID PID:200014 NCBI chr14:9,412,677...9,515,565
Ensembl chr14:9,437,301...9,515,561 		JBrowse link
G PARD6A par-6 family cell polarity regulator alpha ISO PID PID:200014 NCBI chr 5:59,781,890...59,783,990 JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 ISO PID
SMPDB		 PID:200014 SMP:00391
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO PID PID:200014 NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316 		JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO SMPDB SMP:00391 NCBI chr21:75,781,812...75,823,404
Ensembl chr21:75,784,648...75,825,496 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO RGD
PID		 PMID:12891559 PID:200014 RGD:1299201 NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519 		JBrowse link
G PIK3R6 phosphoinositide-3-kinase regulatory subunit 6 ISO SMPDB SMP:00391 NCBI chr16:8,158,842...8,224,192
Ensembl chr16:8,159,400...8,223,937 		JBrowse link
G PRKCA protein kinase C alpha ISO RGD PMID:17347799 RGD:1625124 NCBI chr16:54,638,548...55,144,372
Ensembl chr16:54,642,729...54,948,256 		JBrowse link
G PRKCB protein kinase C beta ISO RGD PMID:17347799 RGD:1625124 NCBI chr 5:21,558,608...21,940,536
Ensembl chr 5:21,558,441...21,943,864 		JBrowse link
G PRKCG protein kinase C gamma ISO RGD PMID:17347799 RGD:1625124 NCBI chr 6:46,574,560...46,600,329
Ensembl chr 6:46,575,439...46,600,364 		JBrowse link
G PRKCI protein kinase C iota ISO PID PID:200014 NCBI chr15:19,103,682...19,180,689 JBrowse link
G PRKCQ protein kinase C theta ISO RGD PMID:17347799 RGD:1625124 NCBI chr 9:6,532,438...6,675,708
Ensembl chr 9:6,532,319...6,621,487 		JBrowse link
G PRKCZ protein kinase C zeta ISO PID PID:200014 NCBI chr20:129,367,309...129,502,681
Ensembl chr20:129,365,679...129,485,818 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 ISO PID
RGD		 PMID:7711057 PMID:12850498 PMID:17347799 PID:200014 RGD:1580595 RGD:1625124 RGD:2293185 NCBI chr 2:13,385,681...13,459,180
Ensembl chr 2:13,387,727...13,459,105 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO RGD
PID		 PMID:7711057 PMID:12891559 PID:200014 RGD:1299201 RGD:2293185 NCBI chr11:107,658,495...107,754,457
Ensembl chr11:107,658,453...107,752,637 		JBrowse link
G PTPRA protein tyrosine phosphatase receptor type A ISO PID PID:200014 NCBI chr 2:33,559,634...33,724,446
Ensembl chr 2:33,559,697...33,722,137 		JBrowse link
G PTPRF protein tyrosine phosphatase receptor type F ISO RGD PMID:7711057 PMID:17347799 RGD:1625124 RGD:2293185 NCBI chr20:89,192,426...89,284,989
Ensembl chr20:89,191,660...89,284,970 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase ISO SMPDB SMP:00391 NCBI chr22:48,560,270...48,643,537
Ensembl chr22:48,561,161...48,618,020 		JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 ISO PID PID:200014 NCBI chr12:6,407,030...6,566,200
Ensembl chr12:6,437,454...6,567,436 		JBrowse link
G RASA1 RAS p21 protein activator 1 ISO PID PID:200014 NCBI chr 4:81,249,851...81,371,486
Ensembl chr 4:81,249,805...81,370,453 		JBrowse link
G RHOQ ras homolog family member Q ISO PID PID:200014 NCBI chr14:60,605,881...60,648,444
Ensembl chr14:60,608,998...60,648,193 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 ISO PID PID:200014 NCBI chr16:33,498,098...33,556,553
Ensembl chr16:33,497,392...33,556,453 		JBrowse link
G SGK1 serum/glucocorticoid regulated kinase 1 ISO PID PID:200014 NCBI chr13:39,152,289...39,306,190
Ensembl chr13:39,300,567...39,306,183 		JBrowse link
G SH2B2 SH2B adaptor protein 2 ISO PID
RGD		 PMID:17347799 PID:200014 RGD:1625124 NCBI chr28:10,862,922...10,900,967
Ensembl chr28:10,864,188...10,883,437 		JBrowse link
G SHC1 SHC adaptor protein 1 ISO SMPDB
PID
RGD		 PMID:17347799 PID:200014 RGD:1625124 SMP:00391 NCBI chr20:8,854,189...8,866,406
Ensembl chr20:8,858,458...8,866,610 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 ISO SMPDB SMP:00391 NCBI chr16:6,654,626...6,660,640
Ensembl chr16:6,654,608...6,661,495 		JBrowse link
G SOCS1 suppressor of cytokine signaling 1 ISO RGD PMID:17010638 RGD:1625125 NCBI chr 5:10,731,866...10,733,745
Ensembl chr 5:10,732,350...10,732,991 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 ISO RGD PMID:17010638 RGD:1625125 NCBI chr16:70,353,099...70,356,401
Ensembl chr16:70,354,746...70,355,423 		JBrowse link
G SOCS6 suppressor of cytokine signaling 6 ISO RGD PMID:17010638 RGD:1625125 NCBI chr18:9,445,820...9,488,125
Ensembl chr18:9,449,740...9,451,347 		JBrowse link
G SOCS7 suppressor of cytokine signaling 7 ISO RGD PMID:17010638 RGD:1625125 NCBI chr16:67,784,644...67,839,456
Ensembl chr16:67,794,258...67,839,040 		JBrowse link
G SORBS1 sorbin and SH3 domain containing 1 ISO PID PID:200014 NCBI chr 9:88,475,783...88,729,912
Ensembl chr 9:88,472,946...88,729,851 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO PID
SMPDB
RGD		 PMID:12891559 PID:200014 RGD:1299201 SMP:00391 NCBI chr14:68,259,509...68,404,167
Ensembl chr14:68,259,360...68,399,895 		JBrowse link
G SOS2 SOS Ras/Rho guanine nucleotide exchange factor 2 ISO RGD PMID:12891559 RGD:1299201 NCBI chr24:27,183,571...27,302,201
Ensembl chr24:27,182,991...27,302,141 		JBrowse link
G TRIP10 thyroid hormone receptor interactor 10 ISO PID PID:200014 NCBI chr 6:6,308,678...6,321,141
Ensembl chr 6:6,308,666...6,320,255 		JBrowse link
insulin-like growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO PID PID:200100 NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698 		JBrowse link
G BAD BCL2 associated agonist of cell death ISO PID PID:200100 NCBI chr 1:9,949,717...9,964,433
Ensembl chr 1:9,949,762...9,964,432 		JBrowse link
G BCAR1 BCAR1 scaffold protein, Cas family member ISO PID PID:200100 NCBI chr 5:60,709,409...60,749,071
Ensembl chr 5:60,707,006...60,732,882 		JBrowse link
G CRK CRK proto-oncogene, adaptor protein ISO PID PID:200100 NCBI chr16:1,102,485...1,135,225
Ensembl chr16:1,102,348...1,135,166 		JBrowse link
G CRKL CRK like proto-oncogene, adaptor protein ISO PID PID:200100
G ESR1 estrogen receptor 1 ISO RGD PMID:20042609 RGD:7242068 NCBI chr13:79,153,418...79,554,552
Ensembl chr13:79,270,265...79,554,549 		JBrowse link
G GRB10 growth factor receptor bound protein 10 ISO PID PID:200100 NCBI chr21:8,022,483...8,225,339
Ensembl chr21:8,063,238...8,225,664 		JBrowse link
G GRB2 growth factor receptor bound protein 2 ISO PID
RGD		 PMID:15272025 PID:200100 RGD:1581313 NCBI chr16:46,264,818...46,346,426
Ensembl chr16:46,264,825...46,347,156 		JBrowse link
G HRAS HRas proto-oncogene, GTPase ISO PID PID:200100 NCBI chr 1:343,613...345,782
Ensembl chr 1:343,506...346,637 		JBrowse link
G IGF1 insulin like growth factor 1 ISO RGD
PID		 PMID:7526037 PMID:15862547 PMID:16083987 PID:200100 RGD:12904768 RGD:1580473 RGD:1626333 NCBI chr11:97,624,498...97,708,730
Ensembl chr11:97,631,189...97,707,308 		JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO RGD
PID		 PMID:15272025 PMID:15862547 PMID:20042609 PID:200100 RGD:1581313 RGD:1626333 RGD:7242068 NCBI chr29:17,212,206...17,534,036
Ensembl chr29:17,459,404...17,526,930 		JBrowse link
G IGF2 insulin like growth factor 2 ISO RGD PMID:15862547 RGD:1626333 NCBI chr 1:1,937,414...1,951,238
Ensembl chr 1:1,936,830...1,945,388 		JBrowse link
G IGFALS insulin like growth factor binding protein acid labile subunit ISO RGD PMID:15862547 RGD:1626333 NCBI chr 5:1,698,787...1,704,205
Ensembl chr 5:1,698,978...1,701,972 		JBrowse link
G IGFBP1 insulin like growth factor binding protein 1 ISO RGD PMID:15862547 RGD:1626333 NCBI chr21:12,932,727...12,939,078
Ensembl chr21:12,932,732...12,937,891 		JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 ISO RGD PMID:15862547 RGD:1626333 NCBI chr10:102,469,611...102,503,229
Ensembl chr10:102,469,669...102,503,276 		JBrowse link
G IGFBP3 insulin like growth factor binding protein 3 ISO RGD PMID:15862547 RGD:1626333 NCBI chr21:12,905,309...12,914,199
Ensembl chr21:12,905,280...12,914,205 		JBrowse link
G IGFBP4 insulin like growth factor binding protein 4 ISO RGD PMID:15862547 RGD:1626333 NCBI chr16:65,722,216...65,737,380
Ensembl chr16:65,723,361...65,737,072 		JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 ISO RGD PMID:15862547 RGD:1626333 NCBI chr10:102,510,939...102,531,710
Ensembl chr10:102,510,897...102,531,724 		JBrowse link
G IGFBP6 insulin like growth factor binding protein 6 ISO RGD PMID:15862547 RGD:1626333 NCBI chr11:49,209,135...49,213,803
Ensembl chr11:49,209,136...49,213,858 		JBrowse link
G IRS1 insulin receptor substrate 1 ISO RGD
PID		 PMID:15272025 PID:200100 RGD:1581313 NCBI chr10:112,748,283...112,812,368 JBrowse link
G IRS2 insulin receptor substrate 2 ISO PID PID:200100 NCBI chr 3:88,045,439...88,076,468 JBrowse link
G NCK2 NCK adaptor protein 2 ISO PID PID:200100 NCBI chr14:9,412,677...9,515,565
Ensembl chr14:9,437,301...9,515,561 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 ISO PID PID:200100
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO PID PID:200100 NCBI chr15:10,218,034...10,304,874
Ensembl chr15:10,218,805...10,294,316 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO PID PID:200100 NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519 		JBrowse link
G PRKCD protein kinase C delta ISO PID PID:200100 NCBI chr22:14,561,401...14,592,877
Ensembl chr22:14,565,282...14,592,873 		JBrowse link
G PRKCZ protein kinase C zeta ISO PID PID:200100 NCBI chr20:129,367,309...129,502,681
Ensembl chr20:129,365,679...129,485,818 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 ISO PID PID:200100 NCBI chr 2:13,385,681...13,459,180
Ensembl chr 2:13,387,727...13,459,105 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO PID PID:200100 NCBI chr11:107,658,495...107,754,457
Ensembl chr11:107,658,453...107,752,637 		JBrowse link
G PXN paxillin ISO PID PID:200100 NCBI chr11:115,560,859...115,619,093
Ensembl chr11:115,560,662...115,619,029 		JBrowse link
G RACK1 receptor for activated C kinase 1 ISO PID PID:200100 NCBI chr23:82,800,211...82,805,769
Ensembl chr23:82,798,085...82,805,936 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase ISO PID PID:200100 NCBI chr22:48,560,270...48,643,537
Ensembl chr22:48,561,161...48,618,020 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 ISO PID PID:200100 NCBI chr16:33,498,098...33,556,553
Ensembl chr16:33,497,392...33,556,453 		JBrowse link
G SHC1 SHC adaptor protein 1 ISO PID PID:200100 NCBI chr20:8,854,189...8,866,406
Ensembl chr20:8,858,458...8,866,610 		JBrowse link
G SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 ISO PID PID:200100 NCBI chr14:68,259,509...68,404,167
Ensembl chr14:68,259,360...68,399,895 		JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon ISO PID PID:200100 NCBI chr16:1,031,840...1,086,950
Ensembl chr16:1,035,250...1,087,013 		JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta ISO PID PID:200100 NCBI chr 8:95,786,197...95,821,270
Ensembl chr 8:95,788,305...95,819,197 		JBrowse link
leptin system pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IRS1 insulin receptor substrate 1 ISO RGD PMID:15316008 RGD:2302071 NCBI chr10:112,748,283...112,812,368 JBrowse link
G IRS2 insulin receptor substrate 2 ISO RGD PMID:15316008 RGD:2302071 NCBI chr 3:88,045,439...88,076,468 JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:15316008 PMID:17010638 RGD:1625125 RGD:2302071 NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710 		JBrowse link
G LEP leptin ISO RGD PMID:9070213 PMID:9618284 PMID:11102451 PMID:12079865 PMID:17010638 RGD:1357909 RGD:1625125 RGD:2290293 RGD:2290294 RGD:61790 NCBI chr21:97,056,913...97,071,161
Ensembl chr21:97,057,529...97,071,220 		JBrowse link
G LEPR leptin receptor ISO RGD PMID:9070213 PMID:9618284 PMID:11102451 PMID:12079865 PMID:17010638 More... RGD:1357909 RGD:1600611 RGD:1625125 RGD:2290293 RGD:2290294 RGD:61790 NCBI chr20:67,454,205...67,567,524
Ensembl chr20:67,454,334...67,524,229 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 ISO RGD PMID:15821101 RGD:2289366 NCBI chr 2:13,385,681...13,459,180
Ensembl chr 2:13,387,727...13,459,105 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO RGD PMID:17872473 RGD:2289807 NCBI chr11:107,658,495...107,754,457
Ensembl chr11:107,658,453...107,752,637 		JBrowse link
G SH2B1 SH2B adaptor protein 1 ISO RGD PMID:15316008 RGD:2302071 NCBI chr 5:26,197,483...26,208,332
Ensembl chr 5:26,196,778...26,207,398 		JBrowse link
G SOCS3 suppressor of cytokine signaling 3 ISO RGD PMID:17010638 RGD:1625125 NCBI chr16:70,353,099...70,356,401
Ensembl chr16:70,354,746...70,355,423 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO RGD PMID:17010638 PMID:17229951 RGD:1600611 RGD:1625125 NCBI chr16:63,877,884...63,957,894
Ensembl chr16:63,922,862...63,957,984 		JBrowse link
luteinizing hormone signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY2 adenylate cyclase 2 ISO SMPDB SMP:00338 NCBI chr 4:6,989,077...7,415,282
Ensembl chr 4:6,989,169...7,414,617 		JBrowse link
G CGA glycoprotein hormones, alpha polypeptide ISO SMPDB SMP:00338 NCBI chr13:11,560,543...11,578,070
Ensembl chr13:11,560,222...11,578,093 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 ISO SMPDB SMP:00338 NCBI chr10:93,316,774...93,395,187
Ensembl chr10:93,316,840...93,388,832 		JBrowse link
G ESR1 estrogen receptor 1 ISO SMPDB SMP:00338 NCBI chr13:79,153,418...79,554,552
Ensembl chr13:79,270,265...79,554,549 		JBrowse link
G GNB1 G protein subunit beta 1 ISO SMPDB SMP:00338 NCBI chr20:129,654,890...129,765,765
Ensembl chr20:129,707,085...129,766,667 		JBrowse link
G GNG12 G protein subunit gamma 12 ISO SMPDB SMP:00338 NCBI chr20:65,280,816...65,409,685
Ensembl chr20:65,403,471...65,405,699 		JBrowse link
G LHB luteinizing hormone subunit beta ISO SMPDB SMP:00338 NCBI chr 6:42,247,254...42,248,822 JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor ISO SMPDB SMP:00338 NCBI chr14:58,413,334...58,479,124
Ensembl chr14:58,413,993...58,477,987 		JBrowse link
G LOC103243509 neuroendocrine secretory protein 55 ISO SMPDB SMP:00338 NCBI chr 2:5,233,893...5,303,433
Ensembl chr 2:5,233,874...5,249,192 		JBrowse link
G PPP1CA protein phosphatase 1 catalytic subunit alpha ISO SMPDB SMP:00338 NCBI chr 1:6,862,536...6,866,212
Ensembl chr 1:6,862,540...6,865,855 		JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00338 NCBI chr20:49,109,774...49,273,200
Ensembl chr20:49,108,425...49,178,806 		JBrowse link
melanocortin system pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY2 adenylate cyclase 2 ISO SMPDB SMP:00310 NCBI chr 4:6,989,077...7,415,282
Ensembl chr 4:6,989,169...7,414,617 		JBrowse link
G AGRP agouti related neuropeptide ISO RGD PMID:10875247 PMID:15189116 RGD:1357925 RGD:632165 NCBI chr 5:59,972,728...59,974,728
Ensembl chr 5:59,973,922...59,974,660 		JBrowse link
G ASIP agouti signaling protein ISO RGD PMID:15189116 RGD:1357925 NCBI chr 2:38,479,328...38,568,756 JBrowse link
G ATRN attractin ISO RGD PMID:20654690 RGD:5144214 NCBI chr 2:34,157,240...34,335,902
Ensembl chr 2:34,157,293...34,335,923 		JBrowse link
G ATRNL1 attractin like 1 ISO RGD PMID:20654690 RGD:5144214 NCBI chr 9:107,957,778...108,760,606
Ensembl chr 9:107,984,442...108,511,042 		JBrowse link
G CPE carboxypeptidase E ISO RGD PMID:11874690 RGD:1357926 NCBI chr 7:111,747,265...111,867,548
Ensembl chr 7:111,747,172...111,868,754 		JBrowse link
G GNB1 G protein subunit beta 1 ISO SMPDB SMP:00310 NCBI chr20:129,654,890...129,765,765
Ensembl chr20:129,707,085...129,766,667 		JBrowse link
G GNG12 G protein subunit gamma 12 ISO SMPDB SMP:00310 NCBI chr20:65,280,816...65,409,685
Ensembl chr20:65,403,471...65,405,699 		JBrowse link
G LOC103243509 neuroendocrine secretory protein 55 ISO SMPDB
RGD		 PMID:20852827 RGD:5144213 SMP:00310 NCBI chr 2:5,233,893...5,303,433
Ensembl chr 2:5,233,874...5,249,192 		JBrowse link
G MC2R melanocortin 2 receptor ISO RGD
SMPDB		 PMID:20852827 RGD:5144213 SMP:00310 NCBI chr18:72,286,380...72,296,607
Ensembl chr18:72,288,224...72,289,105 		JBrowse link
G MC3R melanocortin 3 receptor ISO RGD PMID:8415620 PMID:20852827 RGD:5144213 RGD:69884 NCBI chr 2:7,867,355...7,871,292
Ensembl chr 2:7,869,518...7,870,489 		JBrowse link
G MC4R melanocortin 4 receptor ISO RGD PMID:11963824 PMID:15189116 PMID:20852827 RGD:1357925 RGD:5144213 RGD:729360 NCBI chr18:19,380,054...19,386,412
Ensembl chr18:19,380,849...19,381,847 		JBrowse link
G MC5R melanocortin 5 receptor ISO RGD PMID:9512481 PMID:20852827 RGD:1626223 RGD:5144213 NCBI chr18:72,263,016...72,268,436
Ensembl chr18:72,264,815...72,265,792 		JBrowse link
G MGRN1 mahogunin ring finger 1 ISO RGD PMID:20654690 RGD:5144214 NCBI chr 5:4,310,924...4,372,896
Ensembl chr 5:4,310,970...4,375,423 		JBrowse link
G MRAP melanocortin 2 receptor accessory protein ISO RGD PMID:20654690 RGD:5144214 NCBI chr 2:59,815,547...59,834,674
Ensembl chr 2:59,814,095...59,834,610 		JBrowse link
G MRAP2 melanocortin 2 receptor accessory protein 2 ISO RGD PMID:20654690 RGD:5144214 NCBI chr13:8,709,501...8,764,142 JBrowse link
G PAM peptidylglycine alpha-amidating monooxygenase ISO RGD PMID:11874690 RGD:1357926 NCBI chr23:6,316,428...6,482,959
Ensembl chr23:6,316,428...6,486,751 		JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 ISO RGD PMID:11874690 PMID:15189116 RGD:1357925 RGD:1357926 NCBI chr 4:90,246,413...90,289,148
Ensembl chr 4:90,248,598...90,289,089 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO RGD PMID:11874690 RGD:1357926 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB
RGD		 PMID:11874690 PMID:15189116 RGD:1357925 RGD:1357926 SMP:00310 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00310 NCBI chr20:49,109,774...49,273,200
Ensembl chr20:49,108,425...49,178,806 		JBrowse link
G SDC1 syndecan 1 ISO RGD PMID:15189116 RGD:1357925 NCBI chr14:87,499,732...87,523,122
Ensembl chr14:87,499,574...87,525,026 		JBrowse link
G SDC3 syndecan 3 ISO RGD PMID:15189116 RGD:1357925
natriuretic peptide signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPR3 natriuretic peptide receptor 3 ISO RGD PMID:12829435 RGD:1581460 NCBI chr 4:31,984,712...32,062,593
Ensembl chr 4:31,986,217...32,062,199 		JBrowse link
orexin/hypocretin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HCRT hypocretin neuropeptide precursor ISO RGD PMID:17299454 RGD:1642016 NCBI chr16:64,083,199...64,085,393
Ensembl chr16:64,084,070...64,085,292 		JBrowse link
G HCRTR1 hypocretin receptor 1 ISO RGD PMID:17299454 RGD:1642016 NCBI chr20:101,241,742...101,252,841
Ensembl chr20:101,243,586...101,251,349 		JBrowse link
G HCRTR2 hypocretin receptor 2 ISO RGD PMID:17299454 RGD:1642016 NCBI chr17:16,258,262...16,371,576
Ensembl chr17:16,258,439...16,294,204 		JBrowse link
orexin/hypocretin signaling pathway via orexin/hypocretin receptor 1 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GNAQ G protein subunit alpha q ISO RGD PMID:12890892 RGD:1642020 NCBI chr12:88,666,375...88,988,989
Ensembl chr12:88,670,424...88,871,154 		JBrowse link
G HCRT hypocretin neuropeptide precursor ISO RGD PMID:12890892 RGD:1642020 NCBI chr16:64,083,199...64,085,393
Ensembl chr16:64,084,070...64,085,292 		JBrowse link
G HCRTR1 hypocretin receptor 1 ISO RGD PMID:12890892 RGD:1642020 NCBI chr20:101,241,742...101,252,841
Ensembl chr20:101,243,586...101,251,349 		JBrowse link
orexin/hypocretin signaling pathway via orexin/hypocretin receptor 2 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GNAI1 G protein subunit alpha i1 ISO RGD PMID:12890892 RGD:1642020 NCBI chr21:68,687,809...68,770,415
Ensembl chr21:68,687,307...68,770,360 		JBrowse link
G GNAQ G protein subunit alpha q ISO RGD PMID:12890892 RGD:1642020 NCBI chr12:88,666,375...88,988,989
Ensembl chr12:88,670,424...88,871,154 		JBrowse link
G HCRT hypocretin neuropeptide precursor ISO RGD PMID:12890892 RGD:1642020 NCBI chr16:64,083,199...64,085,393
Ensembl chr16:64,084,070...64,085,292 		JBrowse link
G HCRTR2 hypocretin receptor 2 ISO RGD PMID:12890892 RGD:1642020 NCBI chr17:16,258,262...16,371,576
Ensembl chr17:16,258,439...16,294,204 		JBrowse link
oxytocin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GNA11 G protein subunit alpha 11 ISO RGD PMID:14624682 RGD:1579891 NCBI chr 6:2,858,880...2,887,694
Ensembl chr 6:2,858,937...2,887,704 		JBrowse link
G GNAQ G protein subunit alpha q ISO RGD PMID:14624682 RGD:1579891 NCBI chr12:88,666,375...88,988,989
Ensembl chr12:88,670,424...88,871,154 		JBrowse link
G OXT oxytocin/neurophysin I prepropeptide ISO RGD PMID:14624682 PMID:15821089 RGD:1579891 RGD:1579892 NCBI chr 2:33,749,520...33,750,981
Ensembl chr 2:33,750,108...33,750,968 		JBrowse link
G OXTR oxytocin receptor ISO RGD PMID:14624682 PMID:15821089 RGD:1579891 RGD:1579892 NCBI chr22:44,746,108...44,764,501
Ensembl chr22:44,742,419...44,763,243 		JBrowse link
parathyroid hormone signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARRB1 arrestin beta 1 ISO RGD PMID:20703892 RGD:7207469 NCBI chr 1:66,489,358...66,580,167
Ensembl chr 1:66,490,102...66,580,154 		JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:20703892 RGD:7207469 NCBI chr16:4,191,040...4,202,382
Ensembl chr16:4,191,172...4,202,385 		JBrowse link
G EZR ezrin ISO RGD PMID:21777186 RGD:7207465 NCBI chr13:86,342,954...86,399,827
Ensembl chr13:86,344,051...86,370,622 		JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:19395963 RGD:7207470 NCBI chr 1:6,975,202...6,995,369
Ensembl chr 1:6,975,002...6,995,259 		JBrowse link
G NHERF1 NHERF family PDZ scaffold protein 1 ISO RGD PMID:21777186 RGD:7207465 NCBI chr16:46,889,454...46,910,776
Ensembl chr16:46,888,942...46,910,842 		JBrowse link
G NHERF2 NHERF family PDZ scaffold protein 2 ISO RGD PMID:21777186 RGD:7207465 NCBI chr 5:1,923,773...1,935,641
Ensembl chr 5:1,924,131...1,939,062 		JBrowse link
G PTH parathyroid hormone ISO RGD PMID:9054374 PMID:19395963 PMID:21777186 RGD:7207455 RGD:7207465 RGD:7207470 NCBI chr 1:51,327,555...51,330,810 JBrowse link
G PTH1R parathyroid hormone 1 receptor ISO RGD PMID:9054374 PMID:19395963 PMID:20703892 PMID:21777186 RGD:7207455 RGD:7207465 RGD:7207469 RGD:7207470 NCBI chr22:8,287,877...8,309,736
Ensembl chr22:8,289,398...8,311,256 		JBrowse link
somatostatin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:23073237 RGD:13792788 NCBI chr 1:6,975,202...6,995,369
Ensembl chr 1:6,975,002...6,995,259 		JBrowse link
G JAK2 Janus kinase 2 ISO RGD PMID:17021051 RGD:1641809 NCBI chr12:74,421,243...74,566,766
Ensembl chr12:74,421,016...74,566,710 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 ISO RGD PMID:17021051 RGD:1641809 NCBI chr11:107,658,495...107,754,457
Ensembl chr11:107,658,453...107,752,637 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J ISO RGD PMID:17021051 RGD:1641809 NCBI chr 1:17,137,896...17,328,836
Ensembl chr 1:17,135,907...17,328,590 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:17021051 RGD:1641809 NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776 		JBrowse link
G SST somatostatin ISO RGD PMID:17021051 RGD:1641809 NCBI chr15:81,946,287...81,947,775
Ensembl chr15:81,946,206...81,947,790 		JBrowse link
G SSTR1 somatostatin receptor 1 ISO RGD PMID:17021051 RGD:1641809 NCBI chr24:15,000,190...15,006,757
Ensembl chr24:15,003,116...15,004,291 		JBrowse link
vasopressin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY6 adenylate cyclase 6 ISO RGD PMID:15579502 PMID:18431594 PMID:18971210 RGD:2312654 RGD:2312656 RGD:2313211 NCBI chr11:45,006,220...45,031,481
Ensembl chr11:45,005,637...45,025,501 		JBrowse link
G AKAP7 A-kinase anchoring protein 7 ISO RGD PMID:15037626 PMID:18431594 RGD:1303982 RGD:2312656 NCBI chr13:42,270,160...42,418,728 JBrowse link
G AQP2 aquaporin 2 ISO RGD PMID:15037626 PMID:15579502 PMID:18431594 PMID:18971210 RGD:1303982 RGD:2312654 RGD:2312656 RGD:2313211 NCBI chr11:46,179,783...46,188,631
Ensembl chr11:46,180,387...46,188,712 		JBrowse link
G AVP arginine vasopressin ISO RGD PMID:12942143 PMID:14624682 PMID:18299204 PMID:18431594 RGD:1358326 RGD:1579891 RGD:2301920 RGD:2312656 NCBI chr 2:33,761,066...33,764,608
Ensembl chr 2:33,761,140...33,763,172 		JBrowse link
G AVPR1A arginine vasopressin receptor 1A ISO RGD PMID:12942143 PMID:14624682 RGD:1358326 RGD:1579891 NCBI chr11:59,074,699...59,079,710
Ensembl chr11:59,071,202...59,079,596 		JBrowse link
G AVPR1B arginine vasopressin receptor 1B ISO RGD PMID:7624319 PMID:14624682 PMID:19047484 RGD:1579891 RGD:2312649 RGD:61542 NCBI chr25:23,234,651...23,244,403
Ensembl chr25:23,234,823...23,241,159 		JBrowse link
G AVPR2 arginine vasopressin receptor 2 ISO RGD PMID:11882591 PMID:14624682 PMID:18431594 PMID:18971210 RGD:1579891 RGD:2312654 RGD:2312656 RGD:628560 NCBI chr  X:128,328,728...128,331,482
Ensembl chr  X:128,329,449...128,331,019 		JBrowse link
G GNA11 G protein subunit alpha 11 ISO RGD PMID:14624682 RGD:1579891 NCBI chr 6:2,858,880...2,887,694
Ensembl chr 6:2,858,937...2,887,704 		JBrowse link
G GNAQ G protein subunit alpha q ISO RGD PMID:14624682 RGD:1579891 NCBI chr12:88,666,375...88,988,989
Ensembl chr12:88,670,424...88,871,154 		JBrowse link
G LOC103221883 uncharacterized LOC103221883 ISO RGD PMID:18431594 RGD:2312656 NCBI chr 4:55,148,012...56,665,684
Ensembl chr 4:55,153,563...55,390,027 		JBrowse link
G LOC103243509 neuroendocrine secretory protein 55 ISO RGD PMID:14624682 PMID:15579502 PMID:18431594 PMID:18971210 RGD:1579891 RGD:2312654 RGD:2312656 RGD:2313211 NCBI chr 2:5,233,893...5,303,433
Ensembl chr 2:5,233,874...5,249,192 		JBrowse link
G MYO5B myosin VB ISO RGD PMID:17156409 PMID:18431594 RGD:2312655 RGD:2312656 NCBI chr18:30,759,345...31,143,139
Ensembl chr18:30,759,764...31,143,474 		JBrowse link
G RAB11A RAB11A, member RAS oncogene family ISO RGD PMID:17156409 PMID:18431594 RGD:2312655 RGD:2312656 NCBI chr26:17,682,629...17,702,325
Ensembl chr26:17,682,874...17,702,309 		JBrowse link
G RAB11FIP2 RAB11 family interacting protein 2 ISO RGD PMID:17156409 PMID:18431594 RGD:2312655 RGD:2312656 NCBI chr 9:110,805,236...110,846,691
Ensembl chr 9:110,805,022...110,846,830 		JBrowse link
G SIPA1 signal-induced proliferation-associated 1 ISO RGD PMID:18431594 RGD:2312656 NCBI chr 1:8,588,221...8,601,310
Ensembl chr 1:8,586,685...8,598,455 		JBrowse link
G SNAP23 synaptosome associated protein 23 ISO RGD PMID:18431594 RGD:2312656 NCBI chr26:40,443,478...40,485,211
Ensembl chr26:40,442,615...40,482,346 		JBrowse link
G VAMP2 vesicle associated membrane protein 2 ISO RGD PMID:18431594 RGD:2312656 NCBI chr16:7,539,098...7,542,466 JBrowse link
vasopressin signaling pathway via receptor type 1 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AVP arginine vasopressin ISO RGD PMID:14624682 RGD:1579891 NCBI chr 2:33,761,066...33,764,608
Ensembl chr 2:33,761,140...33,763,172 		JBrowse link
G AVPR1A arginine vasopressin receptor 1A ISO RGD PMID:14624682 RGD:1579891 NCBI chr11:59,074,699...59,079,710
Ensembl chr11:59,071,202...59,079,596 		JBrowse link
G AVPR1B arginine vasopressin receptor 1B ISO RGD PMID:14624682 RGD:1579891 NCBI chr25:23,234,651...23,244,403
Ensembl chr25:23,234,823...23,241,159 		JBrowse link
G GNA11 G protein subunit alpha 11 ISO RGD PMID:14624682 RGD:1579891 NCBI chr 6:2,858,880...2,887,694
Ensembl chr 6:2,858,937...2,887,704 		JBrowse link
G GNAQ G protein subunit alpha q ISO RGD PMID:14624682 RGD:1579891 NCBI chr12:88,666,375...88,988,989
Ensembl chr12:88,670,424...88,871,154 		JBrowse link
vasopressin signaling pathway via receptor type 2 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY2 adenylate cyclase 2 ISO SMPDB SMP:00322 NCBI chr 4:6,989,077...7,415,282
Ensembl chr 4:6,989,169...7,414,617 		JBrowse link
G ADCY6 adenylate cyclase 6 ISO RGD PMID:15579502 PMID:18431594 PMID:18971210 RGD:2312654 RGD:2312656 RGD:2313211 NCBI chr11:45,006,220...45,031,481
Ensembl chr11:45,005,637...45,025,501 		JBrowse link
G AKAP7 A-kinase anchoring protein 7 ISO RGD PMID:15037626 PMID:18431594 RGD:1303982 RGD:2312656 NCBI chr13:42,270,160...42,418,728 JBrowse link
G AQP2 aquaporin 2 ISO RGD PMID:15037626 PMID:15579502 PMID:18431594 PMID:18971210 RGD:1303982 RGD:2312654 RGD:2312656 RGD:2313211 NCBI chr11:46,179,783...46,188,631
Ensembl chr11:46,180,387...46,188,712 		JBrowse link
G AVP arginine vasopressin ISO RGD PMID:14624682 PMID:18431594 RGD:1579891 RGD:2312656 NCBI chr 2:33,761,066...33,764,608
Ensembl chr 2:33,761,140...33,763,172 		JBrowse link
G AVPR2 arginine vasopressin receptor 2 ISO SMPDB
RGD		 PMID:14624682 PMID:18431594 PMID:18971210 RGD:1579891 RGD:2312654 RGD:2312656 SMP:00322 NCBI chr  X:128,328,728...128,331,482
Ensembl chr  X:128,329,449...128,331,019 		JBrowse link
G FSHR follicle stimulating hormone receptor ISO SMPDB SMP:00322 NCBI chr14:58,013,405...58,211,528
Ensembl chr14:58,013,742...58,212,755 		JBrowse link
G GNB1 G protein subunit beta 1 ISO SMPDB SMP:00322 NCBI chr20:129,654,890...129,765,765
Ensembl chr20:129,707,085...129,766,667 		JBrowse link
G GNG12 G protein subunit gamma 12 ISO SMPDB SMP:00322 NCBI chr20:65,280,816...65,409,685
Ensembl chr20:65,403,471...65,405,699 		JBrowse link
G LOC103221883 uncharacterized LOC103221883 ISO RGD PMID:18431594 RGD:2312656 NCBI chr 4:55,148,012...56,665,684
Ensembl chr 4:55,153,563...55,390,027 		JBrowse link
G LOC103243509 neuroendocrine secretory protein 55 ISO RGD
SMPDB		 PMID:14624682 PMID:15579502 PMID:18431594 PMID:18971210 RGD:1579891 RGD:2312654 RGD:2312656 RGD:2313211 SMP:00322 NCBI chr 2:5,233,893...5,303,433
Ensembl chr 2:5,233,874...5,249,192 		JBrowse link
G MYO5B myosin VB ISO RGD PMID:18431594 RGD:2312656 NCBI chr18:30,759,345...31,143,139
Ensembl chr18:30,759,764...31,143,474 		JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta ISO SMPDB SMP:00322 NCBI chr20:49,109,774...49,273,200
Ensembl chr20:49,108,425...49,178,806 		JBrowse link
G RAB11A RAB11A, member RAS oncogene family ISO RGD PMID:18431594 RGD:2312656 NCBI chr26:17,682,629...17,702,325
Ensembl chr26:17,682,874...17,702,309 		JBrowse link
G RAB11FIP2 RAB11 family interacting protein 2 ISO RGD PMID:18431594 RGD:2312656 NCBI chr 9:110,805,236...110,846,691
Ensembl chr 9:110,805,022...110,846,830 		JBrowse link
G SIPA1 signal-induced proliferation-associated 1 ISO RGD PMID:18431594 RGD:2312656 NCBI chr 1:8,588,221...8,601,310
Ensembl chr 1:8,586,685...8,598,455 		JBrowse link
G SNAP23 synaptosome associated protein 23 ISO RGD PMID:18431594 RGD:2312656 NCBI chr26:40,443,478...40,485,211
Ensembl chr26:40,442,615...40,482,346 		JBrowse link
G VAMP2 vesicle associated membrane protein 2 ISO RGD PMID:18431594 RGD:2312656 NCBI chr16:7,539,098...7,542,466 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4028
    signaling pathway 1919
      hormone signaling pathway 377
        peptide and protein hormone signaling pathway 270
          adiponectin signaling pathway + 3
          altered peptide and protein hormone signaling pathway + 10
          angiotensin signaling pathway + 39
          apelin signaling pathway 2
          corticotropin-releasing hormone signaling pathway 12
          endothelin signaling pathway 65
          erythropoietin signaling pathway 34
          follicle-stimulating hormone signaling pathway 12
          ghrelin system pathway 2
          glucagon signaling pathway + 5
          glucagon-like peptide-1 signaling pathway 0
          glucose-dependent insulinotropic peptide signaling pathway 0
          gonadotropin-releasing hormone signaling pathway 0
          growth hormone signaling pathway 2
          insulin signaling pathway + 64
          insulin-like growth factor signaling pathway + 37
          leptin system pathway + 11
          luteinizing hormone signaling pathway 11
          melanocortin system pathway + 23
          natriuretic peptide signaling pathway + 7
          orexin/hypocretin signaling pathway + 5
          oxytocin signaling pathway 4
          parathyroid hormone family signaling pathway + 8
          prolactin signaling pathway 0
          somatostatin signaling pathway 7
          thyroid-stimulating hormone signaling pathway 0
          thyrotropin-releasing hormone signaling pathway 0
          vasopressin signaling pathway + 22
paths to the root