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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
adenosine monophosphate-activated protein kinase (AMPK) signaling pathway   
adiponectin signaling pathway +   
altered energy homeostasis pathway +    
altered peptide and protein hormone signaling pathway +    
angiotensin signaling pathway +    
apelin signaling pathway  
citric acid cycle pathway +    
corticotropin-releasing hormone signaling pathway   
endothelin signaling pathway  
erythropoietin signaling pathway  
follicle-stimulating hormone signaling pathway  
ghrelin system pathway  
glucagon signaling pathway +    
glucagon-like peptide-1 signaling pathway 
glucose-dependent insulinotropic peptide signaling pathway 
gonadotropin-releasing hormone signaling pathway  
growth hormone signaling pathway  
insulin signaling pathway +     
insulin-like growth factor signaling pathway +   
leptin system pathway +    
Leptin acts on two populations of hypothalamic neurons that express orexigenic (feeding inducing) and anorexigenic genes, respectively. Leptin reduces the expression of genes from the former and enhances the expression of genes from the latter neurons. The leptin mediated response acts primarily via Jak-dependent activation of STAT.

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luteinizing hormone signaling pathway  
melanocortin system pathway +    
mTOR signaling pathway +    
natriuretic peptide signaling pathway +   
orexin/hypocretin signaling pathway +   
oxidative phosphorylation pathway +   
oxytocin signaling pathway  
parathyroid hormone family signaling pathway +    
prolactin signaling pathway 
somatostatin signaling pathway  
thyroid-stimulating hormone signaling pathway 
thyrotropin-releasing hormone signaling pathway 
vasopressin signaling pathway +     

Synonyms
Related Synonyms: Signaling by Leptin ;   leptin-mediated signaling pathway
Definition Sources: GO:0033210, PMID:11239410, PMID:12079865, Reactome:R-HSA-2586552

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