MGRN1 (mahogunin ring finger 1) - Rat Genome Database

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Gene: MGRN1 (mahogunin ring finger 1) Chlorocebus sabaeus
Analyze
Symbol: MGRN1
Name: mahogunin ring finger 1
RGD ID: 18790081
Description: ENCODES a protein that exhibits metal ion binding (inferred); transferase activity (inferred); ubiquitin protein ligase activity (inferred); INVOLVED IN heart development (ortholog); protein polyubiquitination (ortholog); protein ubiquitination (ortholog); PARTICIPATES IN melanocortin system pathway; ASSOCIATED WITH epilepsy (ortholog); hyperglycemia (ortholog); hyperinsulinism (ortholog); FOUND IN cytoplasm (inferred); early endosome (inferred); endoplasmic reticulum (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: E3 ubiquitin-protein ligase MGRN1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.154,310,924 - 4,372,896 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl54,310,970 - 4,375,423 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606826,292,411 - 26,363,923 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MGRN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.154,310,924 - 4,372,896 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl54,310,970 - 4,375,423 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606826,292,411 - 26,363,923 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
MGRN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38164,624,826 - 4,690,972 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl164,616,493 - 4,690,974 (+)EnsemblGRCh38hg38GRCh38
GRCh37164,674,827 - 4,740,973 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36164,614,854 - 4,680,974 (+)NCBINCBI36Build 36hg18NCBI36
Build 34164,614,853 - 4,680,972NCBI
Celera164,883,683 - 4,949,753 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef164,641,815 - 4,707,494 (+)NCBIHuRef
CHM1_1164,674,882 - 4,741,756 (+)NCBICHM1_1
T2T-CHM13v2.0164,654,281 - 4,720,424 (+)NCBIT2T-CHM13v2.0
Mgrn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39164,703,964 - 4,756,160 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl164,704,113 - 4,756,160 (+)EnsemblGRCm39 Ensembl
GRCm38164,886,100 - 4,938,296 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl164,886,249 - 4,938,296 (+)EnsemblGRCm38mm10GRCm38
MGSCv37164,886,252 - 4,938,296 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36164,801,480 - 4,853,524 (+)NCBIMGSCv36mm8
Celera165,517,662 - 5,569,636 (+)NCBICelera
Cytogenetic Map16A1NCBI
cM Map162.48NCBI
Mgrn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81011,142,626 - 11,194,773 (-)NCBIGRCr8
mRatBN7.21010,638,881 - 10,688,332 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1010,638,880 - 10,688,315 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1015,348,233 - 15,396,588 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01014,837,050 - 14,885,406 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01010,506,186 - 10,554,831 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01010,832,573 - 10,881,999 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1010,833,519 - 10,881,977 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0109,599,503 - 9,648,909 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41010,756,804 - 10,805,883 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11010,756,804 - 10,805,883 (-)NCBI
Celera109,604,036 - 9,652,494 (-)NCBICelera
Cytogenetic Map10q12NCBI
Mgrn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544212,781,539 - 12,824,222 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544212,780,795 - 12,823,716 (-)NCBIChiLan1.0ChiLan1.0
MGRN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2185,154,386 - 5,219,725 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1168,944,813 - 9,009,883 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0163,550,352 - 3,615,693 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1164,740,763 - 4,782,638 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl164,740,763 - 4,782,638 (+)Ensemblpanpan1.1panPan2
MGRN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1636,716,071 - 36,775,893 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl636,716,343 - 36,769,417 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha638,050,260 - 38,103,958 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0636,919,892 - 36,979,309 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl636,918,610 - 36,979,312 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1636,713,739 - 36,773,816 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0636,606,581 - 36,666,904 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0637,009,268 - 37,068,750 (-)NCBIUU_Cfam_GSD_1.0
Mgrn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344106,801,950 - 106,847,702 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365304,652,464 - 4,693,999 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365304,647,550 - 4,693,143 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MGRN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl337,694,808 - 37,748,067 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1337,694,798 - 37,748,106 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2338,753,414 - 38,806,811 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Mgrn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248242,420,203 - 2,470,627 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248242,419,973 - 2,473,580 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 20 36 36 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000007129   ⟹   ENSCSAP00000005317
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl54,310,970 - 4,368,273 (+)Ensembl
Ensembl Acc Id: ENSCSAT00000007133   ⟹   ENSCSAP00000005322
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl54,310,970 - 4,375,423 (+)Ensembl
RefSeq Acc Id: XM_007984411   ⟹   XP_007982602
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.154,310,925 - 4,371,055 (+)NCBI
Vero_WHO_p1.0NW_02366606826,292,411 - 26,363,922 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007984421   ⟹   XP_007982612
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.154,310,926 - 4,372,896 (+)NCBI
Vero_WHO_p1.0NW_02366606826,292,411 - 26,363,921 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007984430   ⟹   XP_007982621
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.154,310,925 - 4,371,055 (+)NCBI
Vero_WHO_p1.0NW_02366606826,292,411 - 26,363,922 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007984440   ⟹   XP_007982631
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.154,310,926 - 4,372,896 (+)NCBI
Vero_WHO_p1.0NW_02366606826,292,411 - 26,363,920 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007984448   ⟹   XP_007982639
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.154,310,924 - 4,370,821 (+)NCBI
Vero_WHO_p1.0NW_02366606826,294,436 - 26,363,923 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007984457   ⟹   XP_007982648
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.154,310,925 - 4,370,821 (+)NCBI
Vero_WHO_p1.0NW_02366606826,294,436 - 26,363,921 (-)NCBI
Sequence:
RefSeq Acc Id: XM_007984467   ⟹   XP_007982658
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.154,310,925 - 4,370,821 (+)NCBI
Vero_WHO_p1.0NW_02366606826,294,436 - 26,363,921 (-)NCBI
Sequence:
RefSeq Acc Id: XM_037989893   ⟹   XP_037845821
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366606826,294,436 - 26,363,922 (-)NCBI
RefSeq Acc Id: XP_007982639   ⟸   XM_007984448
- Peptide Label: isoform X5
- UniProtKB: A0A0D9R9M8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007982602   ⟸   XM_007984411
- Peptide Label: isoform X1
- UniProtKB: A0A0D9R9N3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007982621   ⟸   XM_007984430
- Peptide Label: isoform X3
- UniProtKB: A0A0D9R9N3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007982648   ⟸   XM_007984457
- Peptide Label: isoform X6
- UniProtKB: A0A0D9R9M8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007982658   ⟸   XM_007984467
- Peptide Label: isoform X8
- UniProtKB: A0A0D9R9M8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007982612   ⟸   XM_007984421
- Peptide Label: isoform X2
- UniProtKB: A0A0D9R9N3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_007982631   ⟸   XM_007984440
- Peptide Label: isoform X4
- UniProtKB: A0A0D9R9N3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000005317   ⟸   ENSCSAT00000007129
Ensembl Acc Id: ENSCSAP00000005322   ⟸   ENSCSAT00000007133
RefSeq Acc Id: XP_037845821   ⟸   XM_037989893
- Peptide Label: isoform X7
- UniProtKB: A0A0D9R9M8 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000009073 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000007129.1 UniProtKB/TrEMBL
  ENSCSAT00000007133.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro MGRN1/RNF157-like UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene MGRN1 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE MGRN1 UniProtKB/TrEMBL
  PTHR22996 UniProtKB/TrEMBL
Pfam zf-C3HC4_3 UniProtKB/TrEMBL
PROSITE ZF_RING_2 UniProtKB/TrEMBL
SMART RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt A0A0D9R9M8 ENTREZGENE, UniProtKB/TrEMBL
  A0A0D9R9N3 ENTREZGENE, UniProtKB/TrEMBL