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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).

Term:vasopressin signaling pathway
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Accession:PW:0000491 term browser browse the term
Definition:The hormone vasopressin plays central roles in cardiovascular and water homeostasis by signaling via two receptor types, G-protein coupled receptors coupling to particular G alpha subunits of heterotrimeric G proteins.
Synonyms:related_synonym: Avp signaling pathway;   arginine-vasopressin signaling pathway

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vasopressin signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy6 adenylate cyclase 6 IMP
ISO
IDA
RGD PMID:18971210, PMID:18431594, PMID:15579502 RGD:2312654, RGD:2312656, RGD:2313211 NCBI chr 7:140,270,678...140,291,722
Ensembl chr 7:140,270,692...140,291,620
JBrowse link
G Akap7 A-kinase anchoring protein 7 IDA
ISO
RGD PMID:15037626, PMID:18431594 RGD:1303982, RGD:2312656 NCBI chr 1:21,129,213...21,263,850
Ensembl chr 1:21,141,970...21,263,850
JBrowse link
G Aqp2 aquaporin 2 IDA
TAS
IMP
RGD PMID:15037626, PMID:18431594, PMID:15579502, PMID:18971210 RGD:1303982, RGD:2312656, RGD:2313211, RGD:2312654 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165
JBrowse link
G Avp arginine vasopressin TAS
ISO
IMP
RGD PMID:12942143, PMID:18431594, PMID:14624682, PMID:18299204 RGD:1358326, RGD:2312656, RGD:1579891, RGD:2301920 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Avpr1a arginine vasopressin receptor 1A TAS
ISO
RGD PMID:12942143, PMID:14624682 RGD:1358326, RGD:1579891 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Avpr1b arginine vasopressin receptor 1B TAS
ISO
IDA
RGD PMID:7624319, PMID:14624682, PMID:19047484 RGD:61542, RGD:1579891, RGD:2312649 NCBI chr13:48,367,307...48,378,831
Ensembl chr13:48,367,307...48,378,831
JBrowse link
G Avpr2 arginine vasopressin receptor 2 TAS
ISO
IMP
RGD PMID:11882591, PMID:18431594, PMID:14624682, PMID:18971210 RGD:628560, RGD:2312656, RGD:1579891, RGD:2312654 NCBI chr  X:156,889,006...156,892,707
Ensembl chr  X:156,889,410...156,891,213
JBrowse link
G Gna11 G protein subunit alpha 11 ISO RGD PMID:14624682 RGD:1579891 NCBI chr 7:11,033,400...11,047,284
Ensembl chr 7:11,033,317...11,047,437
JBrowse link
G Gnaq G protein subunit alpha q ISO RGD PMID:14624682 RGD:1579891 NCBI chr 1:233,382,778...233,622,584
Ensembl chr 1:233,382,708...233,622,786
JBrowse link
G Gnas GNAS complex locus IMP
ISO
IDA
RGD PMID:18971210, PMID:18431594, PMID:15579502, PMID:14624682 RGD:2312654, RGD:2312656, RGD:2313211, RGD:1579891 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Myo5b myosin Vb IMP
TAS
RGD PMID:17156409, PMID:18431594 RGD:2312655, RGD:2312656 NCBI chr18:70,426,865...70,729,985
Ensembl chr18:70,427,007...70,729,030
JBrowse link
G Pde4d phosphodiesterase 4D ISO RGD PMID:18431594 RGD:2312656 NCBI chr 2:40,219,999...41,468,551
Ensembl chr 2:40,554,146...41,464,264
JBrowse link
G Rab11a RAB11a, member RAS oncogene family ISO RGD PMID:17156409, PMID:18431594 RGD:2312655, RGD:2312656 NCBI chr 8:70,192,975...70,215,719
Ensembl chr 8:70,192,975...70,215,719
JBrowse link
G Rab11fip2 RAB11 family interacting protein 2 ISO RGD PMID:17156409, PMID:18431594 RGD:2312655, RGD:2312656 NCBI chr 1:281,065,346...281,101,163
Ensembl chr 1:281,065,168...281,101,438
JBrowse link
G Sipa1 signal-induced proliferation-associated 1 ISO RGD PMID:18431594 RGD:2312656 NCBI chr 1:221,006,305...221,018,820
Ensembl chr 1:221,006,340...221,015,929
JBrowse link
G Snap23 synaptosome associated protein 23 TAS RGD PMID:18431594 RGD:2312656 NCBI chr 3:112,333,972...112,362,960 JBrowse link
G Vamp2 vesicle-associated membrane protein 2 ISO RGD PMID:18431594 RGD:2312656 NCBI chr10:55,675,171...55,679,405
Ensembl chr10:55,675,575...55,679,450
JBrowse link
vasopressin signaling pathway via receptor type 1 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avp arginine vasopressin ISO RGD PMID:14624682 RGD:1579891 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Avpr1a arginine vasopressin receptor 1A ISO RGD PMID:14624682 RGD:1579891 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Avpr1b arginine vasopressin receptor 1B ISO RGD PMID:14624682 RGD:1579891 NCBI chr13:48,367,307...48,378,831
Ensembl chr13:48,367,307...48,378,831
JBrowse link
G Gna11 G protein subunit alpha 11 ISO RGD PMID:14624682 RGD:1579891 NCBI chr 7:11,033,400...11,047,284
Ensembl chr 7:11,033,317...11,047,437
JBrowse link
G Gnaq G protein subunit alpha q ISO RGD PMID:14624682 RGD:1579891 NCBI chr 1:233,382,778...233,622,584
Ensembl chr 1:233,382,708...233,622,786
JBrowse link
vasopressin signaling pathway via receptor type 2 term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy2 adenylate cyclase 2 ISO SMPDB SMP:00322 NCBI chr 1:37,043,071...37,698,390
Ensembl chr 1:37,507,276...37,698,390
JBrowse link
G Adcy3 adenylate cyclase 3 IEA KEGG rno:04962 NCBI chr 6:28,570,941...28,648,848
Ensembl chr 6:28,571,351...28,650,148
JBrowse link
G Adcy6 adenylate cyclase 6 ISO
IEA
IMP
IDA
KEGG PMID:18431594, PMID:18971210, PMID:15579502 rno:04962, RGD:2312656, RGD:2312654, RGD:2313211 NCBI chr 7:140,270,678...140,291,722
Ensembl chr 7:140,270,692...140,291,620
JBrowse link
G Adcy9 adenylate cyclase 9 IEA KEGG rno:04962 NCBI chr10:11,392,698...11,515,406
Ensembl chr10:11,392,625...11,512,600
JBrowse link
G Akap7 A-kinase anchoring protein 7 ISO
IDA
RGD PMID:18431594, PMID:15037626 RGD:2312656, RGD:1303982 NCBI chr 1:21,129,213...21,263,850
Ensembl chr 1:21,141,970...21,263,850
JBrowse link
G Aqp2 aquaporin 2 TAS
IEA
IDA
IMP
KEGG PMID:18431594, PMID:15037626, PMID:18971210, PMID:15579502 rno:04962, RGD:2312656, RGD:1303982, RGD:2312654, RGD:2313211 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) IEA KEGG rno:04962 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Aqp4 aquaporin 4 IEA KEGG rno:04962 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha IEA KEGG rno:04962 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta IEA KEGG rno:04962 NCBI chr 4:170,913,920...170,932,789
Ensembl chr 4:170,913,923...170,932,618
JBrowse link
G Avp arginine vasopressin TAS
IEA
ISO
KEGG PMID:18431594, PMID:14624682 rno:04962, RGD:2312656, RGD:1579891 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Avpr2 arginine vasopressin receptor 2 TAS
ISO
IEA
IMP
SMPDB
KEGG
PMID:18431594, PMID:18971210, PMID:14624682 SMP:00322, rno:04962, RGD:2312656, RGD:2312654, RGD:1579891 NCBI chr  X:156,889,006...156,892,707
Ensembl chr  X:156,889,410...156,891,213
JBrowse link
G Creb1 cAMP responsive element binding protein 1 IEA KEGG rno:04962 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 IEA KEGG rno:04962 NCBI chr 3:80,892,433...80,933,283
Ensembl chr 3:80,892,435...80,933,283
JBrowse link
G Creb3l2 cAMP responsive element binding protein 3-like 2 IEA KEGG rno:04962 NCBI chr 4:64,869,285...64,981,519
Ensembl chr 4:64,869,026...64,981,384
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 IEA KEGG rno:04962 NCBI chr 7:11,490,852...11,499,287
Ensembl chr 7:11,490,852...11,499,282
JBrowse link
G Creb3l4 cAMP responsive element binding protein 3-like 4 IEA KEGG rno:04962 NCBI chr 2:189,596,657...189,602,243
Ensembl chr 2:189,595,415...189,602,143
JBrowse link
G Dctn1 dynactin subunit 1 IEA KEGG rno:04962 NCBI chr 4:114,876,770...114,896,567
Ensembl chr 4:114,876,770...114,896,573
JBrowse link
G Dctn2 dynactin subunit 2 IEA KEGG rno:04962 NCBI chr 7:70,555,953...70,571,433
Ensembl chr 7:70,556,019...70,572,614
JBrowse link
G Dctn4 dynactin subunit 4 IEA KEGG rno:04962 NCBI chr18:55,797,188...55,824,195
Ensembl chr18:55,797,198...55,822,036
JBrowse link
G Dctn5 dynactin subunit 5 IEA KEGG rno:04962 NCBI chr 1:192,088,709...192,105,421
Ensembl chr 1:192,088,672...192,105,429
JBrowse link
G Dctn6 dynactin subunit 6 IEA KEGG rno:04962 NCBI chr16:61,795,544...61,814,734
Ensembl chr16:61,795,432...61,814,733
JBrowse link
G Dync1h1 dynein cytoplasmic 1 heavy chain 1 IEA KEGG rno:04962 NCBI chr 6:134,958,854...135,085,769
Ensembl chr 6:134,958,854...135,085,769
JBrowse link
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 IEA KEGG rno:04962 NCBI chr 4:30,807,755...31,121,097
Ensembl chr 4:30,807,879...31,121,090
JBrowse link
G Dync1i2 dynein cytoplasmic 1 intermediate chain 2 IEA KEGG rno:04962 NCBI chr 3:57,817,677...57,868,854
Ensembl chr 3:57,817,693...57,868,854
JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 IEA KEGG rno:04962 NCBI chr 8:122,743,274...122,776,801
Ensembl chr 8:122,743,189...122,776,806
JBrowse link
G Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 IEA KEGG rno:04962 NCBI chr19:740,007...762,897
Ensembl chr19:740,028...762,897
JBrowse link
G Dync2h1 dynein cytoplasmic 2 heavy chain 1 IEA KEGG rno:04962 NCBI chr 8:5,217,054...5,436,969
Ensembl chr 8:5,217,217...5,429,581
JBrowse link
G Dync2li1 dynein cytoplasmic 2 light intermediate chain 1 IEA KEGG rno:04962 NCBI chr 6:7,900,962...7,933,795
Ensembl chr 6:7,900,972...7,933,796
JBrowse link
G Dynll1 dynein light chain LC8-type 1 IEA KEGG rno:04962 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572
JBrowse link
G Dynll2 dynein light chain LC8-type 2 IEA KEGG rno:04962 NCBI chr10:75,262,536...75,281,302
Ensembl chr10:75,262,537...75,270,561
JBrowse link
G Fshr follicle stimulating hormone receptor ISO SMPDB SMP:00322 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G Gnas GNAS complex locus ISO
IEA
IMP
IDA
SMPDB
KEGG
PMID:18431594, PMID:18971210, PMID:15579502, PMID:14624682 SMP:00322, rno:04962, RGD:2312656, RGD:2312654, RGD:2313211, RGD:1579891 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Gnb1 G protein subunit beta 1 ISO SMPDB SMP:00322 NCBI chr 5:172,914,025...172,981,403
Ensembl chr 5:172,934,990...172,979,986
JBrowse link
G Gng12 G protein subunit gamma 12 ISO SMPDB SMP:00322 NCBI chr 4:97,634,925...97,763,478
Ensembl chr 4:97,657,671...97,760,102
JBrowse link
G Myo5b myosin Vb TAS RGD PMID:18431594 RGD:2312656 NCBI chr18:70,426,865...70,729,985
Ensembl chr18:70,427,007...70,729,030
JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase IEA KEGG rno:04962 NCBI chr10:91,879,608...91,986,242
Ensembl chr10:91,878,633...92,008,082
JBrowse link
G Pde4d phosphodiesterase 4D ISO RGD PMID:18431594 RGD:2312656 NCBI chr 2:40,219,999...41,468,551
Ensembl chr 2:40,554,146...41,464,264
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha IEA KEGG rno:04962 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta IEA
ISO
KEGG
SMPDB
SMP:00322, rno:04962 NCBI chr 2:252,602,197...252,691,886
Ensembl chr 2:252,605,307...252,691,886
JBrowse link
G Prkx protein kinase, X-linked IEA KEGG rno:04962 NCBI chr  X:45,080,963...45,125,095
Ensembl chr  X:45,080,963...45,124,270
JBrowse link
G Rab11a RAB11a, member RAS oncogene family ISO
IEA
KEGG PMID:18431594 rno:04962, RGD:2312656 NCBI chr 8:70,192,975...70,215,719
Ensembl chr 8:70,192,975...70,215,719
JBrowse link
G Rab11b RAB11B, member RAS oncogene family IEA KEGG rno:04962 NCBI chr 7:18,598,991...18,612,132
Ensembl chr 7:18,598,880...18,612,147
JBrowse link
G Rab11fip2 RAB11 family interacting protein 2 ISO RGD PMID:18431594 RGD:2312656 NCBI chr 1:281,065,346...281,101,163
Ensembl chr 1:281,065,168...281,101,438
JBrowse link
G Rab5a RAB5A, member RAS oncogene family IEA KEGG rno:04962 NCBI chr 9:5,910...6,065 JBrowse link
G Rab5b RAB5B, member RAS oncogene family IEA KEGG rno:04962 NCBI chr 7:3,104,530...3,123,384
Ensembl chr 7:3,104,551...3,123,297
JBrowse link
G Rab5c RAB5C, member RAS oncogene family IEA KEGG rno:04962 NCBI chr10:88,621,924...88,645,364
Ensembl chr10:88,621,925...88,645,364
JBrowse link
G Sipa1 signal-induced proliferation-associated 1 ISO RGD PMID:18431594 RGD:2312656 NCBI chr 1:221,006,305...221,018,820
Ensembl chr 1:221,006,340...221,015,929
JBrowse link
G Snap23 synaptosome associated protein 23 TAS RGD PMID:18431594 RGD:2312656 NCBI chr 3:112,333,972...112,362,960 JBrowse link
G Stx4 syntaxin 4 IEA KEGG rno:04962 NCBI chr 1:199,287,384...199,295,606
Ensembl chr 1:199,287,710...199,294,979
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 ISO
IEA
KEGG PMID:18431594 rno:04962, RGD:2312656 NCBI chr10:55,675,171...55,679,405
Ensembl chr10:55,675,575...55,679,450
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6103
    regulatory pathway 3879
      homeostasis pathway 1775
        cardiovascular system homeostasis pathway 421
          vasopressin signaling pathway 55
            altered vasopressin signaling pathway + 0
            vasopressin signaling pathway via receptor type 1 + 5
            vasopressin signaling pathway via receptor type 2 + 51
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.