OXTR (oxytocin receptor) - Rat Genome Database

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Gene: OXTR (oxytocin receptor) Chlorocebus sabaeus
Analyze
Symbol: OXTR
Name: oxytocin receptor
RGD ID: 18739976
Description: ENCODES a protein that exhibits ionotropic glutamate receptor binding (ortholog); oxytocin receptor activity (ortholog); peptide hormone binding (ortholog); INVOLVED IN digestive tract development (ortholog); eating behavior (ortholog); ERK1 and ERK2 cascade (ortholog); PARTICIPATES IN G protein mediated signaling pathway via Galphai family; G protein mediated signaling pathway via Galphaq family; oxytocin signaling pathway; ASSOCIATED WITH Atrioventricular Septal Defect 2 (ortholog); autism spectrum disorder (ortholog); autistic disorder (ortholog); FOUND IN adherens junction (ortholog); apical plasma membrane (ortholog); microvillus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12244,746,108 - 44,764,501 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2244,742,419 - 44,763,243 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041121,803,523 - 121,822,069 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
OXTR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12244,746,108 - 44,764,501 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2244,742,419 - 44,763,243 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041121,803,523 - 121,822,069 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
OXTR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3838,741,269 - 8,769,613 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl38,750,381 - 8,769,628 (-)EnsemblGRCh38hg38GRCh38
GRCh3738,792,067 - 8,811,299 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3638,767,094 - 8,786,300 (-)NCBINCBI36Build 36hg18NCBI36
Build 3438,767,093 - 8,786,300NCBI
Celera38,726,881 - 8,746,086 (-)NCBICelera
Cytogenetic Map3p25.3NCBI
HuRef38,726,158 - 8,745,365 (-)NCBIHuRef
CHM1_138,742,513 - 8,761,719 (-)NCBICHM1_1
T2T-CHM13v2.038,741,551 - 8,760,789 (-)NCBIT2T-CHM13v2.0
Oxtr
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396112,450,646 - 112,467,800 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6112,450,644 - 112,466,904 (-)EnsemblGRCm39 Ensembl
GRCm386112,473,683 - 112,491,035 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6112,473,683 - 112,489,943 (-)EnsemblGRCm38mm10GRCm38
MGSCv376112,423,678 - 112,439,802 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366112,439,461 - 112,455,585 (-)NCBIMGSCv36mm8
Celera6114,311,708 - 114,327,999 (-)NCBICelera
Cytogenetic Map6E3NCBI
cM Map652.27NCBI
Oxtr
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84147,154,374 - 147,171,723 (-)NCBIGRCr8
mRatBN7.24145,598,549 - 145,614,674 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4145,599,561 - 145,614,674 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4150,990,744 - 151,006,875 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04146,771,550 - 146,787,681 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04145,392,838 - 145,408,958 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04144,399,326 - 144,417,598 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4144,403,358 - 144,416,116 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04207,701,360 - 207,717,840 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44148,314,089 - 148,326,797 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14148,558,929 - 148,571,638 (-)NCBI
Celera4134,168,869 - 134,184,999 (-)NCBICelera
Cytogenetic Map4q41NCBI
Oxtr
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955561337,902 - 354,336 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955561340,387 - 354,499 (-)NCBIChiLan1.0ChiLan1.0
OXTR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v228,760,557 - 8,779,263 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan138,765,328 - 8,784,021 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v038,701,344 - 8,721,706 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.138,962,454 - 8,963,730 (-)NCBIpanpan1.1PanPan1.1panPan2
OXTR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1209,358,797 - 9,382,308 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl209,358,916 - 9,378,343 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha209,392,409 - 9,411,729 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0209,388,927 - 9,412,408 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl209,388,090 - 9,410,068 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1209,110,306 - 9,130,001 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0209,455,823 - 9,475,105 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0209,429,314 - 9,449,013 (+)NCBIUU_Cfam_GSD_1.0
Oxtr
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494214,650,853 - 14,668,467 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366024,241,737 - 4,260,549 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366024,241,743 - 4,259,866 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OXTR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1365,134,057 - 65,153,487 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11365,134,055 - 65,155,543 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21372,415,345 - 72,436,029 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Oxtr
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247313,370,701 - 3,385,640 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247313,367,645 - 3,384,815 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system hemolymphoid system nervous system
High
Medium
Low 14 11 22
Below cutoff 22 6 38

Sequence


Reference Sequences
RefSeq Acc Id: ENSCSAT00000008882   ⟹   ENSCSAP00000007016
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2244,742,419 - 44,763,243 (-)Ensembl
RefSeq Acc Id: XM_007985098   ⟹   XP_007983289
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12244,746,108 - 44,764,501 (-)NCBI
Vero_WHO_p1.0NW_023666041121,803,523 - 121,822,069 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_007983289 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000007016.1
Reference Protein Sequences
RefSeq Acc Id: XP_007983289   ⟸   XM_007985098
- UniProtKB: A0A0D9REH7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCSAP00000007016   ⟸   ENSCSAT00000008882


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000010788 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000008882.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  Oxytocn_rcpt UniProtKB/TrEMBL
  Vasoprsn_rcpt UniProtKB/TrEMBL
KEGG Report csab:103227962 UniProtKB/TrEMBL
NCBI Gene OXTR ENTREZGENE
PANTHER NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
  PTHR24241:SF89 UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OXYTOCINR UniProtKB/TrEMBL
  VASOPRESSINR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A0D9REH7 ENTREZGENE, UniProtKB/TrEMBL