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Gene: AQP2 (aquaporin 2) Chlorocebus sabaeus

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Symbol:

AQP2

Name:

aquaporin 2

RGD ID:

18509617

Description:

ENCODES a protein that exhibits actin binding (ortholog); PDZ domain binding (ortholog); INVOLVED IN actin filament depolymerization (ortholog); cell volume homeostasis (ortholog); cellular response to water deprivation (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH cardiomyopathy (ortholog); diabetes insipidus (ortholog); diabetic ketoacidosis (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); clathrin-coated vesicle (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

aquaporin-2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	AQP2 (aquaporin 2)	NCBI	Ortholog
Mus musculus (house mouse):	Aqp2 (aquaporin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Aqp2 (aquaporin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Aqp2 (aquaporin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	AQP2 (aquaporin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	AQP2 (aquaporin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Aqp2 (aquaporin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	AQP2 (aquaporin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Aqp2 (aquaporin 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

ChlSab1.1 - Green Monkey 1.1 Assembly

Position:

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	46,179,783 - 46,188,631 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	46,180,387 - 46,188,712 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	199,932,873 - 199,941,797 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cardiomyopathy (ISO)

diabetes insipidus (ISO)

diabetic ketoacidosis (ISO)

Diabetic Nephropathies (ISO)

Experimental Diabetes Mellitus (ISO)

genetic disease (ISO)

hydronephrosis (ISO)

hypertension (ISO)

nephrogenic diabetes insipidus (ISO)

nephrogenic diabetes insipidus type 2 (ISO)

Polyuria (ISO)

X-linked nephrogenic diabetes insipidus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin filament depolymerization (ISO)

actin filament organization (IEA)

cell volume homeostasis (ISO)

cellular response to copper ion (IEA)

cellular response to mercury ion (IEA)

cellular response to water deprivation (IEA,ISO)

female pregnancy (ISO)

glycerol transmembrane transport (IEA)

hyperosmotic response (ISO)

metanephric collecting duct development (IEA)

positive regulation of calcium ion transport (ISO)

protein homotetramerization (IEA)

renal water homeostasis (IEA,ISO)

renal water transport (IEA,ISO)

response to calcium ion (ISO)

response to glucagon (ISO)

response to hormone (ISO)

response to lipopolysaccharide (ISO)

response to salt stress (ISO)

response to starvation (ISO)

transmembrane transport (IEA)

water transport (IEA,ISO)

Cellular Component

apical plasma membrane (IEA,ISO)

basolateral plasma membrane (IEA,ISO)

clathrin-coated vesicle (ISO)

cytoplasm (IEA)

cytoplasmic vesicle (IEA)

cytoplasmic vesicle membrane (IEA)

early endosome (ISO)

exocytic vesicle (ISO)

extracellular exosome (IEA)

Golgi apparatus (IEA)

lumenal side of membrane (IEA)

membrane (IEA)

perinuclear region of cytoplasm (IEA)

plasma membrane (IEA)

protein-containing complex (ISO)

recycling endosome (IEA)

trans-Golgi network (ISO)

Molecular Function

actin binding (ISO)

channel activity (IEA)

glycerol transmembrane transporter activity (IEA)

PDZ domain binding (ISO)

protein binding (ISO)

water channel activity (IEA)

water transmembrane transporter activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

amiloride pharmacodynamics pathway (ISO)

bendroflumethiazide pharmacodynamics pathway (ISO)

bumetanide pharmacodynamics pathway (ISO)

chlorothiazide pharmacodynamics pathway (ISO)

chlorthalidone pharmacodynamics pathway (ISO)

cystinuria pathway (ISO)

eplerenone pharmacodynamics pathway (ISO)

etacrynic acid pharmacodynamics pathway (ISO)

furosemide pharmacodynamics pathway (ISO)

Hartnup disease pathway (ISO)

hydrochlorothiazide pharmacodynamics pathway (ISO)

hydroflumethiazide pharmacodynamics pathway (ISO)

iminoglycinuria pathway (ISO)

lysinuric protein intolerance pathway (ISO)

metolazone pharmacodynamics pathway (ISO)

spironolactone pharmacodynamics pathway (ISO)

torasemide pharmacodynamics pathway (ISO)

triamterene pharmacodynamics pathway (ISO)

trichlormethiazide pharmacodynamics pathway (ISO)

vasopressin signaling pathway (ISO)

vasopressin signaling pathway via receptor type 2 (ISO)

water transport pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

AQP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	46,179,783 - 46,188,631 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	46,180,387 - 46,188,712 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	199,932,873 - 199,941,797 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

AQP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	49,950,737 - 49,958,878 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	49,950,737 - 49,958,878 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	50,344,520 - 50,352,661 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	48,630,796 - 48,638,931 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	48,630,795 - 48,638,929	NCBI
Celera	12	49,140,628 - 49,148,768 (+)	NCBI		Celera
Cytogenetic Map	12	q13.12	NCBI
HuRef	12	47,376,094 - 47,384,234 (+)	NCBI		HuRef
CHM1_1	12	50,310,689 - 50,318,825 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	49,913,728 - 49,921,869 (+)	NCBI		T2T-CHM13v2.0

Aqp2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	99,476,937 - 99,482,426 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	99,476,936 - 99,482,428 (+)	Ensembl		GRCm39 Ensembl
GRCm38	15	99,579,056 - 99,584,545 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	99,579,055 - 99,584,547 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	99,409,487 - 99,414,976 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	99,407,106 - 99,412,579 (+)	NCBI		MGSCv36	mm8
Celera	15	101,734,478 - 101,739,943 (+)	NCBI		Celera
Cytogenetic Map	15	F1	NCBI
cM Map	15	56.13	NCBI

Aqp2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	132,590,286 - 132,595,321 (+)	NCBI		GRCr8
mRatBN7.2	7	130,711,433 - 130,716,468 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	130,711,413 - 130,716,468 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	132,515,018 - 132,520,055 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	134,740,599 - 134,745,636 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	134,653,120 - 134,658,157 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	141,237,802 - 141,242,837 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	141,237,768 - 141,245,165 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	115,742,312 - 115,747,347 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	138,325,855 - 138,330,891 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	138,402,285 - 138,406,831 (+)	NCBI
Celera	7	127,193,026 - 127,197,996 (+)	NCBI		Celera
Cytogenetic Map	7	q36	NCBI

Aqp2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955547	547,064 - 555,958 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955547	547,770 - 555,764 (+)	NCBI	ChiLan1.0	ChiLan1.0

AQP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	44,229,814 - 44,238,063 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	44,226,576 - 44,234,741 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	38,796,300 - 38,804,559 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	39,690,289 - 39,698,397 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	39,690,289 - 39,698,397 (-)	Ensembl	panpan1.1		panPan2

AQP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	4,743,127 - 4,750,907 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	4,743,127 - 4,750,907 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	41,505,816 - 41,513,596 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	4,793,697 - 4,801,488 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	4,793,697 - 4,801,488 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	4,758,676 - 4,766,460 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	4,748,491 - 4,756,279 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	41,900,444 - 41,908,227 (+)	NCBI		UU_Cfam_GSD_1.0

Aqp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	65,528,160 - 65,536,193 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936512	7,628,495 - 7,634,107 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936512	7,628,677 - 7,633,344 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AQP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	15,863,486 - 15,868,565 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	15,862,739 - 15,868,565 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	16,090,821 - 16,095,902 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Aqp2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624816	2,335,471 - 2,340,828 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624816	2,332,477 - 2,340,797 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in AQP2
212 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	reproductive system
57	32	17	29	29	45	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008003189	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008003190	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JACDXN010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCSAT00000004078 ⟹ ENSCSAP00000002339

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1 Ensembl	11	46,180,387 - 46,188,712 (+)	Ensembl

RefSeq Acc Id:

XM_008003189 ⟹ XP_008001380

Type:

CODING

Position:

Green Monkey Assembly	Chr	Position (strand)	Source
ChlSab1.1	11	46,179,783 - 46,188,631 (+)	NCBI
Vero_WHO_p1.0	NW_023666037	199,932,873 - 199,941,797 (-)	NCBI

Sequence:

show sequence

CATTCAATCCAAACCCCAATCCACTAGGTCAGTTTTATTCTTCCCGTTTTACAGAGAAAGACAA
GAAAGGTTAAGTCACATAGATGGAACAGGCTGATGCCAGAATGGACACCCTCAACTTCCTCAGC
CGCCCCCAGGTTGACTCCATCACCGAGAGCCAGGGTCCCAGTGCCCCCAGGCTCTAGGAGCTGC
TATTTGGCTGGGGCTCCCAGGAGAAGGTGAAGCTTAATGATTTATGGGTGATTAGCTGCAAGAA
TGCAAACGCAGAAGACACAAACCTTTATGCCCTGGAAATCTGTCACAAGCCAACCAGTTGTTTT
CCATCCCTGTGAAGCAGGAGTAATTGGAGGTCTGACAGAAGAACTTCCCAGTTACCACAAGGAG
CAGCACTCATGCACTCTTAGTTTTGTGTGAGGTATTGCCCCTGCCTTGGTCAACAGTTTGAGTC
AGAGAGAGGGGCACTGGGCACAATCCCCACCAGAGGTTCCCATTCACAAGACCCCGTGGGGGCT
GGGAGAGGCCCTGGGGCAGCAGCCCTGGGGTAACCAAGGGAACAAACACGGAAAACCAGGGACG
TCAGTCCTTATCTGGAGCTCATTAAATGGGGAACATCAGTCAGCTGTGAAGGCTAAGATAGGGT
GATAGGCACGTGGGTGGGCTGGGATGGGGCATGGGGGCAGAGGCCGCCATGGAGAAGCGGTATT
GGCCTCAACAACTCCACCTCCCCACCACGTGCCCAGATCCCGGATGGAAGTACCCTATAAATGC
CCACAACCCAGCCTCCCCAGAGGCCTTGAGAAAGAGAGCGGTAGAGAGCGAAAGAGAGTGCCCA
GAGCCTCCTGGCCCTGAGACGGCCGGGCCAGCCACGCAGGACTCCGCAGCATGTGGGAGCTCCG
CTCCATAGCCTTCTCCAGGGCCGTGTTCGCAGAGTTCCTGGCCACACTCCTCTTCGTCTTCTTT
GGCCTCGGCTCGGCTCTCAACTGGCCACAGGCCCTGCCCTCTGTGCTACAGATCGCCATGGCAT
TCGGCTTGGGTATTGGAACCCTGGTACAGGCTCTGGGCCACGTAAGCGGGGCCCACATCAACCC
AGCCGTGACTGTGGCCTGCCTGGTGGGCTGCCATGTCTCCTTTCTCCGAGCCACCTTCTACGTG
GCTGCCCAGCTGCTGGGGGCTGTGGCTGGAGCCGCTCTGCTCCATGAGATCACGCCAGCAGACA
TCCGCGGGGACCTGGCTGTCAATGCTCTCAGCAACAGCACGACAGCTGGCCAGGCGGTGACTGT
GGAGCTCTTCCTGACGCTGCAGCTGGTGCTCTGCATCTTTGCCTCCACCGATGAGCGCCGTGGA
GAGAACCCGGGCACCCCTGCTCTCTCCATAGGCTTCTCCGTGGCCCTGGGCCACCTCCTGGGGA
TCCACTACACCGGCTGCTCTATGAATCCCGCCCGCTCCCTGGCTCCAGCTGTCGTCACTGGCAA
ATTTGATGACCACTGGGTCTTCTGGATCGGACCCCTGGTGGGCGCCATCCTGGGCTCCCTCCTC
TACAACTACGTGCTGTTCCCGCCAGCCAAGAGCCTGTCGGAGCGCCTGGCAGTGCTGAAGGGCC
TGGAGCCGGACACGGACTGGGAGGAGCGCGAGGTGCGGCGGCGACAGTCGGTGGAGCTGCACTC
GCCGCAGAGCCTCCCACGGGGCACCAAGGCCTGAGGGCCGTCAGCGGCCTCTACGGCCCCAATG
GACGCGTGTGAGGCCCGAGGCAGAAGGGCCCACCCCGTCCCTCCTCTCCCCCAGGTCTGAAGTT
GGCCCCCAGCGCAGAGTAGCTGCTTCCTGTACGTGCGCGCCGAGGCCAGTGCTGTGAGCAGGCG
TAGACGAGGCTGCCGGAGGGAGCCCTGAGCCTGGTAGGCCCCCTGCCCTGAGGCTGTGAGCAGC
CAGTAGTGGATCCTCCAGCCTTTTGCAGGGAACGGGGAACTTGGGGGACTGAGCTGGGGAGGGA
GGCAGGTGGGTGGTAAGAGCGAAACTCTTGAGAGCCTGCACCCAGGTACCGGGTGGGGAGTGTA
CAGACCCCTGCCTTGGGGGTTCTGGAAAGAGTGCAACTGGTTTTATTAGTGTGCAAGTGTGTTC
ATCCCCGAGTTCTCCTTTGTCCTCACATGCAGGGTTGTGCATGCCCCTGAGTGTGAACAGGTTT
GCCTACGTTGGTGCAAGTGTGCACGGCTGGGGAATTCTCACTTCCCCTTGCACCCCTTCCTCCC
CAACCTGCAATAAATCCACTTCTGCAGTGGATGAGTGTGGGTGCCAGTCATCCTCAGGGGAAGG
GAAGGAGGACACTTTGAGAGGGCTGAAGGGAGGGCCTTGATTTCCAGCTGCAATCTGGCTCCTC
CTGGAAAATGTCCCCTACCTGCAGCGCTGGGCCCCAAGGCTTGCCAAGACTCATTGCTGGAGGT
AGAGAGGTGTCAACCAGAGAACAGCTCCCCTAGAAATGGCCTCTGGAAAAAGGAAATCTTTGGT
GACCAAAGATTTCCTTTCTGTGGTGAGGGAGAACCTCTCCAAAGAGAAAGCAGGCATATGAGTG
TGCACACCTTCACGTGTGTGTACGCTGTGTGTGCCCAGGACCCCCGTCTCCAGGGGTGCCCCAG
ATCCAGAGATTAGCCTCCCACTTCGGCAGAGAAAACAAAAGCGCTTTGTGGGACCCGGGCCTTT
GTCTTGGGAGAGGGGGAGATTTGCAACTAGACACTTCTTGAAAGGAGACACTCACTTTCCCAAG
TCAGCCCTCTTGCCCAGCACACACCTATGGCTGGCTGGGCAAGGCACTCAGGCATGCAACCATG
GGCACCAGGCAACACCCCTTCATCGCCCATCTCATTCTCCCCAGTCCTCGGGCAGCAGCTCCTC
CGCCCCAGGAACCTCTGTTCCTTCTCTCTCTGCCTCTCCACAGCCTGTGATTCCCTGCTTCTGG
CTCCTACCACTGAACAGTCATTGTGGATAGAGCAGCCTGTTGCGCTCAGGACCAGGGAAGGGAA
ATGACTTCTCCAGGCAGAGGCAGATCTGAGTCTAGAACCCAGGCTTCTAAATTTCTAGGCCAGT
ATGACTGTTCTCAAATGAGATTAACCAGGATTAAGTGAGATGACGCATGTAAAGATGCTGTGTA
AACTGTAATTCTTAATACCATTAACACGCATTACTAGAATCATTTTCATTATTTCTGCTTCCTG
GGGGAAGGATGCAGAAGGAGTTTGATGCTCAACATCCCTTACCTCCTTTCACTGATGGCCAAAG
CAAAGGAGAGTCCTGGGAGCCTGCAAGATCCAGGCAGAAGGAGATGGGTTTGGGGCTGGCCCCA
TCCTGGTCCAGCCTCTTAACCTCTCCTTACCCTGCATGTGTGCCCTAACTTTTCTCCCACCTCC
TTCCTCCCACCACCCAGCCCCATCCATTCTCTCCTTCCATCTCCAGCCTGCTGTATAAGTAATA
TGTGGGTCATACCTTGAAGCCCCCACCCTCATGCTCTCTGTGGCCTCCATGCCTTCAAGACTTC
TGTCTATATCTAGCTCACACTGCACCAAGCACCCACTGTGCACCAGGCACTGAGTCTCTAGCCT
CTTTCTCCCTTCTGCTTCCATCCAAGAAAGACAGTGTATAAGGAACATCTCTGTAATTGTGTCC
CCTCTGATCTATGCTGTTTACTGTCTTCCTTGACCAAAGCTCTCTTTGAGGTCAAAAAAAGGCT
GCCCCAGGCCATAGGTGCTATGGAGAGGACTCTCCCAAACCCCCAATAGCTAGTGACAGCCACT
TGGCCTCACTACCAGAAAAGTGGGGGAGTCAGAAACCAAAGTGACCTCCACAGCTGTCCTCCTG
GCACCTGAGTGTCCTTGCTCTAGAGGTTCAAAGGCAGCAAGGCAGTGAGCTATGAGCCTATCAT
GGATGTGTCTCAGGCACCTCGTCCCCACCCCACCTACCCCAACAAACTCCTCTAGAAGAAGCCA
AGAATTTATCTCTATGTCTGTTTCACTTCTTGGATTGCATCTCCCCCAAAACTAAATATGAAAT
CCCTACCACTTCCAACTTCTATTGCCCATTGGGGTCAGAGGTCAAAAAAGGATTCCAAGTGATG
GAACTCCAGGGGTGAAGGGAAATTGGCAGTTCCTGGCATCTCTTATGTACCAGCTGCTGTGCTG
GGTGCCTTGCATGCAAGGGTTCATCTAATCTTCCTCAAACTTCTGATAGGTTAGGGAAGGACAA
AGGCCCCCAGCCATAAAGAGTTTTGCTATTTCCAAAGCTTCCCCTTATCATCCCCTGTGATTAT
CTCCCAACCTTGTGACAAAGGTAGAGCAAATATTGTTCTTCCCATTTTACAGGTTCAGAAACCA
AGGCTAAGAGACTGGTCTAAAGTCTCACAGGTTCTTTGTCCTGTCTACCCTGCTGCCCTCGCCA
AGGTTCTCTGTCCACTGCAAGACAGTGGGTTGGGTTGGAAAGGTCTAGCCATGTGTTCTGGCTT
CTGCAAGGGCCTCACAGGAGGAGCCTAGGATTTGCCTCGGTGGAAAAATCATGGGATTTTGCAT
AAAAAGCTCTGAGTTCAAGTCTTGGCTCCACTATACACTACATGTGGGGCTGGTTTCTGCCCTT
GAAGAGCACCTGGTTAGTCAGAGAACGGAGATCACTCACACCAAACCATACAGGCAGGGCAGCG
TGGAGACAGGTGGACAGACCTCCAGGTCCCCAAGCTGGGCACAGAGAAGGTTGTGAGCTGTCCC
ATACTCCCACTTTGTACCAAATGACTTTGCACCTGCAAATGGTGCTTCAATGTTGTTTTGTATC
TTTAAGCTGTGATGTTGTATATATATGATGACTCCCAGCTAGACTGTAAGCCCTTTGGGGACAG
GGCTGCTTTCAG

hide sequence

Protein Sequences


Protein RefSeqs	XP_008001380	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCSAP00000002339
	ENSCSAP00000002339.1

RefSeq Acc Id:	XP_008001380 ⟸ XM_008003189
- UniProtKB:	A0A0D9R150 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCSAP00000002339 ⟸ ENSCSAT00000004078

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCSAG00000006042	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCSAT00000004078.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1080.10	UniProtKB/TrEMBL
InterPro	Aquaporin-like	UniProtKB/TrEMBL
	Aquaporin_transptr	UniProtKB/TrEMBL
	MIP	UniProtKB/TrEMBL
	MIP_CS	UniProtKB/TrEMBL
KEGG Report	csab:103238290	UniProtKB/TrEMBL
NCBI Gene	AQP2	ENTREZGENE
PANTHER	AQUAPORIN-2	UniProtKB/TrEMBL
	PTHR19139	UniProtKB/TrEMBL
Pfam	MIP	UniProtKB/TrEMBL
PRINTS	AQUAPORIN2	UniProtKB/TrEMBL
	MINTRINSICP	UniProtKB/TrEMBL
PROSITE	MIP	UniProtKB/TrEMBL
Superfamily-SCOP	SSF81338	UniProtKB/TrEMBL
UniProt	A0A0D9R150	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB