LHB (luteinizing hormone subunit beta) - Rat Genome Database

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Pathways
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Gene: LHB (luteinizing hormone subunit beta) Chlorocebus sabaeus
Analyze
Symbol: LHB
Name: luteinizing hormone subunit beta
RGD ID: 18487173
Description: ENCODES a protein that exhibits hormone activity (inferred); INVOLVED IN luteinizing hormone signaling pathway involved in ovarian follicle development (ortholog); organic cyclic compound metabolic process (ortholog); PARTICIPATES IN luteinizing hormone signaling pathway; ASSOCIATED WITH alcohol use disorder (ortholog); Bradycardia (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN cytoplasm (inferred); extracellular region (inferred); extracellular space (inferred)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: luteinizing hormone beta polypeptide; lutropin subunit beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,247,254 - 42,248,822 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607322,134,416 - 22,135,718 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LHB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,247,254 - 42,248,822 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607322,134,416 - 22,135,718 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LHB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,015,980 - 49,019,498 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,015,980 - 49,017,091 (-)EnsemblGRCh38hg38GRCh38
GRCh371949,519,237 - 49,520,348 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,211,049 - 54,212,159 (-)NCBINCBI36Build 36hg18NCBI36
Build 341954,211,048 - 54,212,159NCBI
Celera1946,386,444 - 46,387,554 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1945,895,957 - 45,897,067 (-)NCBIHuRef
CHM1_11949,521,461 - 49,522,571 (-)NCBICHM1_1
T2T-CHM13v2.01952,010,754 - 52,014,273 (-)NCBIT2T-CHM13v2.0
Lhb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,070,370 - 45,071,278 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,070,244 - 45,071,321 (+)EnsemblGRCm39 Ensembl
GRCm38745,417,608 - 45,421,855 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,418,353 - 45,421,854 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl745,420,820 - 45,421,897 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,676,316 - 52,677,224 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,288,988 - 45,289,896 (+)NCBIMGSCv36mm8
Celera740,876,980 - 40,877,888 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.3NCBI
Lhb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,037,457 - 105,038,446 (+)NCBIGRCr8
mRatBN7.2195,898,269 - 95,901,973 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,900,984 - 95,901,972 (+)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl195,898,267 - 95,901,963 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,286,408 - 101,287,397 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,759,086 - 109,760,075 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,049,485 - 103,050,474 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,409,992 - 101,413,725 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,410,019 - 101,413,724 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,489,421 - 102,493,135 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,892,999 - 95,893,988 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,971,118 - 95,972,098 (+)NCBI
Celera190,156,575 - 90,157,564 (+)NCBICelera
Cytogenetic Map1q22NCBI
Lhb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555591,656,106 - 1,657,192 (+)NCBIChiLan1.0ChiLan1.0
LOC100992969
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,150,366 - 55,159,280 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,069,851 - 57,078,655 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,053,779 - 46,055,250 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11954,738,139 - 54,739,424 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1954,738,139 - 54,739,424 (+)Ensemblpanpan1.1panPan2
LHB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,382,855 - 107,384,029 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
ROS_Cfam_1.01107,907,413 - 107,908,590 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11107,575,256 - 107,576,428 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,221,425 - 107,222,599 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,057,035 - 108,058,209 (+)NCBIUU_Cfam_GSD_1.0
LHB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,263,576 - 54,271,086 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,263,574 - 54,269,286 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,063,469 - 50,065,072 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap6q21NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: NM_001365017   ⟹   NP_001351946
RefSeq Status: VALIDATED
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607322,134,416 - 22,135,532 (-)NCBI
RefSeq Acc Id: XM_037991211   ⟹   XP_037847139
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607322,134,416 - 22,135,247 (-)NCBI
RefSeq Acc Id: XM_037991212   ⟹   XP_037847140
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
Vero_WHO_p1.0NW_02366607322,134,416 - 22,135,718 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001351946 (Get FASTA)   NCBI Sequence Viewer  
  XP_037847139 (Get FASTA)   NCBI Sequence Viewer  
  XP_037847140 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000015280.1
Reference Protein Sequences
RefSeq Acc Id: XP_037847140   ⟸   XM_037991212
- Peptide Label: isoform X2
- UniProtKB: A0A0D9S341 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001351946   ⟸   NM_001365017
- Peptide Label: precursor
- UniProtKB: A0A0D9S341 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_037847139   ⟸   XM_037991211
- Peptide Label: isoform X1
- UniProtKB: A0A0D9S341 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000002766 UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000000784.1 UniProtKB/TrEMBL
Gene3D-CATH Cystine-knot cytokines UniProtKB/TrEMBL
InterPro Cystine-knot_cytokine UniProtKB/TrEMBL
  Glyco_hormone_CN UniProtKB/TrEMBL
  Gonadotropin_bsu UniProtKB/TrEMBL
  Gonadotropin_bsu_CS UniProtKB/TrEMBL
NCBI Gene LHB ENTREZGENE
PANTHER GLYCOPROTEIN HORMONE BETA CHAIN UniProtKB/TrEMBL
  LUTROPIN SUBUNIT BETA UniProtKB/TrEMBL
Pfam Cys_knot UniProtKB/TrEMBL
PROSITE GLYCO_HORMONE_BETA_1 UniProtKB/TrEMBL
  GLYCO_HORMONE_BETA_2 UniProtKB/TrEMBL
SMART GHB UniProtKB/TrEMBL
Superfamily-SCOP Cystine-knot cytokines UniProtKB/TrEMBL
UniProt A0A0D9S341 ENTREZGENE, UniProtKB/TrEMBL