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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:fatty acid
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Accession:CHEBI:35366 term browser browse the term
Definition:Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. Natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated. By extension, the term is sometimes used to embrace all acyclic aliphatic carboxylic acids.
Synonyms:related_synonym: Fettsaeure;   Fettsaeuren;   Formula=CHO2R;   SMILES=OC([*])=O;   acide gras;   acides gras;   acido graso;   acidos grasos;   fatty acids
 alt_id: CHEBI:13633;   CHEBI:24024;   CHEBI:4984
 xref: KEGG:C00162;   PMID:14287444;   PMID:14300208;   PMID:14328676;   Wikipedia:Fatty_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:28868


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(R)-lipoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions EXP Thioctic Acid inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein] CTD PMID:24512358 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183 		JBrowse link
11-deoxyprostaglandin E1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOS3 nitric oxide synthase 3 multiple interactions EXP 11-deoxyprostaglandin E1 inhibits the reaction [Ibuprofen results in decreased expression of NOS3 mRNA] CTD PMID:10525081 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943 		JBrowse link
16,16-dimethylprostaglandin E2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOS3 nitric oxide synthase 3 multiple interactions
increases expression		 EXP 16,16-Dimethylprostaglandin E2 inhibits the reaction [Ibuprofen results in decreased expression of NOS3 mRNA]
16,16-Dimethylprostaglandin E2 results in increased expression of NOS3 mRNA		 CTD PMID:10525081 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943 		JBrowse link
4-phenylbutyric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 multiple interactions EXP 4-phenylbutyric acid inhibits the reaction [Benzo(a)pyrene results in increased expression of ATF4 protein] CTD PMID:36754226 NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,742,967...8,745,368 		JBrowse link
G ATF6 activating transcription factor 6 multiple interactions EXP 4-phenylbutyric acid inhibits the reaction [Benzo(a)pyrene results in increased expression of ATF6 protein] CTD PMID:36754226 NCBI chr 4:88,591,279...88,806,156
Ensembl chr 4:88,591,288...88,805,304 		JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions EXP 4-phenylbutyric acid promotes the reaction [Benzo(a)pyrene results in decreased expression of BCL2L1 protein] CTD PMID:36754226 NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694 		JBrowse link
G CASP3 caspase 3 multiple interactions EXP 4-phenylbutyric acid inhibits the reaction [T-2 Toxin results in increased expression of CASP3 protein modified form] CTD PMID:34637808 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G CLDN1 claudin 1 multiple interactions EXP 4-phenylbutyric acid promotes the reaction [Benzo(a)pyrene results in decreased expression of CLDN1 protein] CTD PMID:36754226 NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657 		JBrowse link
G CLDN3 claudin 3 multiple interactions EXP 4-phenylbutyric acid promotes the reaction [Benzo(a)pyrene results in decreased expression of CLDN3 protein] CTD PMID:36754226 NCBI chr 3:11,019,073...11,020,102
Ensembl chr 3:11,019,073...11,020,102 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions EXP 4-phenylbutyric acid inhibits the reaction [Benzo(a)pyrene results in increased expression of DDIT3 protein] CTD PMID:36754226 NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 multiple interactions EXP 4-phenylbutyric acid inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of ERN1 protein] CTD PMID:36754226 NCBI chr12:14,881,913...14,963,290
Ensembl chr12:14,881,923...14,963,284 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP 4-phenylbutyric acid inhibits the reaction [Benzo(a)pyrene results in increased expression of HSPA5 protein] CTD PMID:36754226 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894 		JBrowse link
G OCLN occludin multiple interactions EXP 4-phenylbutyric acid promotes the reaction [Benzo(a)pyrene results in decreased expression of OCLN protein] CTD PMID:36754226 NCBI chr16:47,600,175...47,652,435
Ensembl chr16:47,600,212...47,654,033 		JBrowse link
G TJP1 tight junction protein 1 multiple interactions EXP 4-phenylbutyric acid promotes the reaction [Benzo(a)pyrene results in decreased expression of TJP1 protein] CTD PMID:36754226 NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,370...145,195,836 		JBrowse link
6-oxoprostaglandin F1alpha term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EDN1 endothelin 1 multiple interactions EXP [15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid co-treated with EDN1 protein] results in decreased chemical synthesis of 6-Ketoprostaglandin F1 alpha CTD PMID:16325014 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
all-trans-retinyl palmitate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDIA3 protein disulfide isomerase family A member 3 increases hydrolysis EXP PDIA3 protein results in increased hydrolysis of retinol palmitate CTD PMID:16798117 NCBI chr 1:127,786,174...127,814,096
Ensembl chr 1:127,785,772...127,814,196 		JBrowse link
alpha-(methylamino)isobutyric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G INS insulin increases uptake
multiple interactions		 EXP INS protein results in increased uptake of 2-(methylamino)isobutyric acid
Dimercaprol inhibits the reaction [oxophenylarsine inhibits the reaction [INS protein results in increased uptake of 2-(methylamino)isobutyric acid]]; oxophenylarsine inhibits the reaction [INS protein results in increased uptake of 2-(methylamino)isobutyric acid]		 CTD PMID:1928324 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841 		JBrowse link
alpha-linolenic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP alpha-Linolenic Acid inhibits the reaction [[Polychlorinated Biphenyls results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; alpha-Linolenic Acid inhibits the reaction [Polychlorinated Biphenyls results in increased expression of PTGS2 mRNA]; alpha-Linolenic Acid inhibits the reaction [Polychlorinated Biphenyls results in increased expression of PTGS2 protein] CTD PMID:18155686 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 multiple interactions EXP alpha-Linolenic Acid inhibits the reaction [Polychlorinated Biphenyls results in increased expression of VCAM1 mRNA]; alpha-Linolenic Acid inhibits the reaction [Polychlorinated Biphenyls results in increased expression of VCAM1 protein] CTD PMID:18155686 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,920...117,511,222 		JBrowse link
bezafibrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 increases expression
increases secretion		 EXP Bezafibrate results in increased expression of APOA1 mRNA
Bezafibrate results in increased secretion of APOA1 protein		 CTD PMID:16530456 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,392...44,218,713 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP Bezafibrate inhibits the reaction [Cisplatin affects the localization of BAX protein] CTD PMID:16316343 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140 		JBrowse link
G BCL2 BCL2 apoptosis regulator increases expression EXP Bezafibrate results in increased expression of BCL2 CTD PMID:16316343 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879 		JBrowse link
G CASP3 caspase 3 multiple interactions EXP Bezafibrate inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein] CTD PMID:16316343 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G CYCS cytochrome c, somatic multiple interactions EXP Bezafibrate inhibits the reaction [Cisplatin affects the localization of CYCS protein] CTD PMID:16316343 NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866 		JBrowse link
G LIPG lipase G, endothelial type decreases expression EXP Bezafibrate results in decreased expression of LIPG mRNA; Bezafibrate results in decreased expression of LIPG protein CTD PMID:15953354 NCBI chr 1:99,081,940...99,110,671
Ensembl chr 1:99,081,938...99,110,874 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha multiple interactions EXP Bezafibrate inhibits the reaction [[Cisplatin results in decreased activity of PPARA protein] which results in increased abundance of Fatty Acids, Nonesterified]; Bezafibrate inhibits the reaction [Cisplatin results in decreased activity of PPARA protein] CTD PMID:16316343 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,741...3,364,239 		JBrowse link
G SCARB1 scavenger receptor class B member 1 affects localization
increases expression		 EXP Bezafibrate affects the localization of SCARB1 protein
Bezafibrate results in increased expression of SCARB1 mRNA		 CTD PMID:16530456 NCBI chr14:28,301,421...28,393,568
Ensembl chr14:28,301,294...28,393,568 		JBrowse link
bucladesine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 increases expression EXP Bucladesine results in increased expression of ATP1A1 protein CTD PMID:28438630 NCBI chr 4:104,353,506...104,384,321
Ensembl chr 4:104,353,508...104,384,547 		JBrowse link
capsaicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCYAP1 adenylate cyclase activating polypeptide 1 multiple interactions EXP Capsaicin inhibits the reaction [ADCYAP1 protein alternative form results in decreased susceptibility to 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid] CTD PMID:14662737 NCBI chr 6:105,414,628...105,422,294
Ensembl chr 6:105,414,631...105,422,294 		JBrowse link
G TAC1 tachykinin precursor 1 increases secretion EXP Capsaicin results in increased secretion of TAC1 protein CTD PMID:10766449 NCBI chr 9:77,197,403...77,206,529
Ensembl chr 9:77,197,536...77,206,523 		JBrowse link
clofibrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACO1 aconitase 1 increases expression EXP Clofibrate results in increased expression of ACO1 mRNA CTD PMID:17363680 NCBI chr10:33,937,833...34,001,895
Ensembl chr10:33,937,833...34,001,900 		JBrowse link
G ACOX1 acyl-CoA oxidase 1 increases expression EXP Clofibrate results in increased expression of ACOX1 mRNA CTD PMID:16896063 PMID:17437637 NCBI chr12:5,450,913...5,479,550
Ensembl chr12:5,439,361...5,479,546 		JBrowse link
G AGT angiotensinogen multiple interactions EXP Clofibrate inhibits the reaction [AGT protein modified form results in increased expression of EDN1 protein] CTD PMID:17105827 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833 		JBrowse link
G ALB albumin decreases expression EXP Clofibrate results in decreased expression of ALB mRNA CTD PMID:16896063 NCBI chr 8:69,643,427...69,663,152
Ensembl chr 8:69,531,487...69,721,696 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression EXP Clofibrate results in increased expression of BAX mRNA CTD PMID:17437637 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140 		JBrowse link
G BCL2L1 BCL2 like 1 decreases expression EXP Clofibrate results in decreased expression of BCL2L1 mRNA CTD PMID:17437637 NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694 		JBrowse link
G CAT catalase increases expression EXP Clofibrate results in increased expression of CAT mRNA CTD PMID:17437637 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A increases expression EXP Clofibrate results in increased expression of CPT1A mRNA CTD PMID:16896063 PMID:17363680 NCBI chr 2:4,250,642...4,293,914
Ensembl chr 2:4,233,099...4,293,911 		JBrowse link
G CTSB cathepsin B increases expression EXP Clofibrate results in increased expression of CTSB mRNA CTD PMID:16896063 NCBI chr14:15,014,139...15,035,081
Ensembl chr14:15,011,711...15,033,877 		JBrowse link
G DIO2 iodothyronine deiodinase 2 decreases expression EXP Clofibrate results in decreased expression of DIO2 mRNA CTD PMID:16896063 NCBI chr 7:103,096,414...103,110,749
Ensembl chr 7:103,096,433...103,323,258 		JBrowse link
G EDN1 endothelin 1 decreases expression
multiple interactions		 EXP Clofibrate results in decreased expression of EDN1 protein
Clofibrate inhibits the reaction [AGT protein modified form results in increased expression of EDN1 protein]; Clofibrate inhibits the reaction [KNG1 protein modified form results in increased expression of EDN1 protein]; Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EDN1 protein]; Nitric Oxide deficiency inhibits the reaction [Clofibrate results in decreased expression of EDN1 protein]		 CTD PMID:17105827 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
G FABP1 fatty acid binding protein 1 increases expression EXP Clofibrate results in increased expression of FABP1 mRNA CTD PMID:17363680 NCBI chr 3:57,850,511...57,854,966
Ensembl chr 3:57,850,499...57,854,956 		JBrowse link
G GPX1 glutathione peroxidase 1 decreases expression EXP Clofibrate results in decreased expression of GPX1 mRNA CTD PMID:17437637 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433 		JBrowse link
G HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression EXP Clofibrate results in increased expression of HMGCS2 mRNA CTD PMID:17363680 NCBI chr 4:101,420,941...101,440,302
Ensembl chr 4:101,420,872...101,438,126 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression EXP Clofibrate results in increased expression of JUN mRNA CTD PMID:17437637 NCBI chr 6:153,686,425...153,687,635
Ensembl chr 6:153,685,682...153,687,636 		JBrowse link
G KNG1 kininogen 1 multiple interactions EXP Clofibrate inhibits the reaction [KNG1 protein modified form results in increased expression of EDN1 protein] CTD PMID:17105827 NCBI chr13:124,521,276...124,557,384
Ensembl chr13:124,521,340...124,557,958 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor increases expression EXP Clofibrate results in increased expression of MYC mRNA CTD PMID:17437637 NCBI chr 4:12,455,141...12,460,360
Ensembl chr 4:12,455,122...12,461,078 		JBrowse link
G NOS3 nitric oxide synthase 3 increases expression
multiple interactions		 EXP Clofibrate results in increased expression of NOS3 protein
calphostin C inhibits the reaction [Clofibrate results in increased expression of NOS3 protein]		 CTD PMID:17105827 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha increases expression
multiple interactions		 EXP Clofibrate results in increased expression of PPARA; Clofibrate results in increased expression of PPARA protein
calphostin C inhibits the reaction [Clofibrate results in increased expression of PPARA protein]; calphostin C inhibits the reaction [Clofibrate results in increased expression of PPARA]; Tetradecanoylphorbol Acetate inhibits the reaction [Clofibrate results in increased expression of PPARA]		 CTD PMID:17105827 PMID:20568414 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,741...3,364,239 		JBrowse link
G SCD stearoyl-CoA desaturase increases expression EXP Clofibrate results in increased expression of SCD mRNA CTD PMID:17363680 NCBI chr14:111,461,560...111,478,033
Ensembl chr14:111,461,569...111,478,020 		JBrowse link
G SLC5A5 solute carrier family 5 member 5 increases expression EXP Clofibrate results in increased expression of SLC5A5 mRNA CTD PMID:16896063 NCBI chr 2:59,869,157...59,885,086
Ensembl chr 2:59,869,155...59,885,266 		JBrowse link
G SOD1 superoxide dismutase 1 increases expression EXP Clofibrate results in increased expression of SOD1 mRNA CTD PMID:17437637 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729 		JBrowse link
G THRA thyroid hormone receptor alpha decreases expression EXP Clofibrate results in decreased expression of THRA mRNA CTD PMID:16896063 NCBI chr12:22,270,506...22,296,684
Ensembl chr12:22,270,062...22,296,618 		JBrowse link
G TNF tumor necrosis factor decreases expression EXP Clofibrate results in decreased expression of TNF mRNA CTD PMID:17437637 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
G TPO thyroid peroxidase increases expression EXP Clofibrate results in increased expression of TPO mRNA CTD PMID:16896063 NCBI chr 3:132,384,677...132,409,750
Ensembl chr 3:132,384,583...132,409,208 		JBrowse link
G TSHR thyroid stimulating hormone receptor increases expression EXP Clofibrate results in increased expression of TSHR mRNA CTD PMID:16896063 NCBI chr 7:103,768,260...103,925,777
Ensembl chr 7:103,768,296...103,925,922 		JBrowse link
G TTR transthyretin decreases expression EXP Clofibrate results in decreased expression of TTR mRNA CTD PMID:16896063 NCBI chr 6:115,496,338...115,503,974
Ensembl chr 6:115,496,326...115,503,977 		JBrowse link
Cloprostenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 increases expression EXP Cloprostenol results in increased expression of HSD3B1 mRNA CTD PMID:15713365 NCBI chr 4:101,565,229...101,574,110 JBrowse link
G LDLR low density lipoprotein receptor decreases expression EXP Cloprostenol results in decreased expression of LDLR mRNA CTD PMID:15713365 NCBI chr 2:69,828,348...69,864,823
Ensembl chr 2:69,828,332...69,864,827 		JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor decreases expression EXP Cloprostenol results in decreased expression of LHCGR mRNA; Cloprostenol results in decreased expression of LHCGR protein CTD PMID:15713365 NCBI chr 3:91,964,415...92,023,821
Ensembl chr 3:91,964,415...92,021,398 		JBrowse link
G NR0B1 nuclear receptor subfamily 0 group B member 1 increases expression EXP Cloprostenol results in increased expression of NR0B1 mRNA CTD PMID:15713365 NCBI chr  X:26,117,874...26,122,951
Ensembl chr  X:26,117,874...26,122,951 		JBrowse link
G STAR steroidogenic acute regulatory protein decreases expression EXP Cloprostenol results in decreased expression of STAR mRNA; Cloprostenol results in decreased expression of STAR protein CTD PMID:15713365 NCBI chr15:48,377,597...48,385,398
Ensembl chr15:48,377,521...48,385,462 		JBrowse link
fenofibrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 affects localization EXP Fenofibrate affects the localization of ABCA1 protein CTD PMID:16530456 NCBI chr 1:246,144,277...246,278,492
Ensembl chr 1:246,144,277...246,278,492 		JBrowse link
G APOA1 apolipoprotein A1 increases secretion
decreases expression
multiple interactions		 EXP Fenofibrate results in increased secretion of APOA1 protein
Fenofibrate results in decreased expression of APOA1 mRNA
Fenofibrate inhibits the reaction [APOA1 protein results in increased transport of Cholesterol]; Fenofibrate promotes the reaction [APOA1 protein results in increased transport of Cholesterol]		 CTD PMID:16530456 NCBI chr 9:44,216,481...44,218,360
Ensembl chr 9:44,216,392...44,218,713 		JBrowse link
G SCARB1 scavenger receptor class B member 1 affects localization EXP Fenofibrate affects the localization of SCARB1 protein CTD PMID:16530456 NCBI chr14:28,301,421...28,393,568
Ensembl chr14:28,301,294...28,393,568 		JBrowse link
G TNF tumor necrosis factor multiple interactions EXP [Fenofibrate co-treated with Zinc] inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased activity of TNF protein] CTD PMID:15226458 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
gabapentin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 affects binding EXP Gabapentin binds to CACNA2D1 protein CTD PMID:11687876 NCBI chr 9:97,781,057...98,265,925
Ensembl chr 9:97,781,090...98,266,969 		JBrowse link
ibuprofen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOS3 nitric oxide synthase 3 decreases expression
multiple interactions		 EXP Ibuprofen results in decreased expression of NOS3 mRNA
11-deoxy-16-phenoxy-17,18,19,20-tetranorprostaglandin E1 inhibits the reaction [Ibuprofen results in decreased expression of NOS3 mRNA]; 11-deoxyprostaglandin E1 inhibits the reaction [Ibuprofen results in decreased expression of NOS3 mRNA]; 16,16-Dimethylprostaglandin E2 inhibits the reaction [Ibuprofen results in decreased expression of NOS3 mRNA]; sulprostone inhibits the reaction [Ibuprofen results in decreased expression of NOS3 mRNA]		 CTD PMID:10525081 PMID:10644584 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943 		JBrowse link
ionomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of CXCL8 protein CTD PMID:15912099 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861 		JBrowse link
leptomycin B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 multiple interactions EXP leptomycin B inhibits the reaction [Warfarin results in increased expression of BMP2 mRNA] CTD PMID:34520801 NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,195 		JBrowse link
linoleic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA5 annexin A5 multiple interactions
increases activity		 EXP Linoleic Acid promotes the reaction [TNF protein results in increased activity of ANXA5 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of ANXA5 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of ANXA5 protein]]; TNF protein promotes the reaction [Linoleic Acid results in increased activity of ANXA5 protein]; Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of ANXA5 protein]]]; Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of ANXA5 protein]]] CTD PMID:10617950 NCBI chr 8:102,387,833...102,420,868
Ensembl chr 8:102,388,103...102,425,750 		JBrowse link
G CASP3 caspase 3 multiple interactions
increases activity		 EXP Linoleic Acid promotes the reaction [TNF protein results in increased activity of CASP3 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of CASP3 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid results in increased activity of CASP3 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of CASP3 protein]]; TNF protein promotes the reaction [Linoleic Acid results in increased activity of CASP3 protein]; Zinc Acetate inhibits the reaction [Linoleic Acid results in increased activity of CASP3 protein]; Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of CASP3 protein]]]; Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid results in increased activity of CASP3 protein]]; Zinc Acetate promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of CASP3 protein]]] CTD PMID:10617950 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G IL6 interleukin 6 increases expression
multiple interactions		 EXP Linoleic Acid results in increased expression of IL6 mRNA; Linoleic Acid results in increased expression of IL6 protein
2,4-thiazolidinedione inhibits the reaction [Linoleic Acid results in increased expression of IL6 protein]; PPARG protein promotes the reaction [Linoleic Acid results in increased expression of IL6 protein]; Quercetin inhibits the reaction [Linoleic Acid results in increased expression of IL6 mRNA]		 CTD PMID:14519784 PMID:15051824 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions
increases activity		 EXP PPARG protein promotes the reaction [Linoleic Acid results in increased activity of RELA protein]; PPARG protein promotes the reaction [Linoleic Acid results in increased expression of IL6 protein]; Quercetin inhibits the reaction [Linoleic Acid results in increased activity of PPARG protein]; Vitamin E inhibits the reaction [Linoleic Acid results in increased activity of PPARG protein] CTD PMID:14519784 PMID:15051824 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions		 EXP Linoleic Acid results in increased expression of PTGS2 mRNA
Linoleic Acid promotes the reaction [[Polychlorinated Biphenyls results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; Linoleic Acid promotes the reaction [Polychlorinated Biphenyls results in increased expression of PTGS2 mRNA]; Linoleic Acid promotes the reaction [Polychlorinated Biphenyls results in increased expression of PTGS2 protein]; Polychlorinated Biphenyls promotes the reaction [[Linoleic Acid results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; prolinedithiocarbamate inhibits the reaction [[Linoleic Acid co-treated with Polychlorinated Biphenyls] results in increased expression of PTGS2 mRNA]; prolinedithiocarbamate inhibits the reaction [Linoleic Acid results in increased expression of PTGS2 mRNA]		 CTD PMID:18155686 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions
increases activity		 EXP 2,4-thiazolidinedione inhibits the reaction [Linoleic Acid results in increased activity of RELA protein]; PPARG protein promotes the reaction [Linoleic Acid results in increased activity of RELA protein] CTD PMID:14519784 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469 		JBrowse link
G TNF tumor necrosis factor multiple interactions EXP Linoleic Acid promotes the reaction [TNF protein results in increased activity of ANXA5 protein]; Linoleic Acid promotes the reaction [TNF protein results in increased activity of CASP3 protein]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of ANXA5 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of CASP3 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of ANXA5 protein]]; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of CASP3 protein]]; TNF protein promotes the reaction [Linoleic Acid results in increased activity of ANXA5 protein]; TNF protein promotes the reaction [Linoleic Acid results in increased activity of CASP3 protein]; Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of ANXA5 protein]]]; Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Linoleic Acid promotes the reaction [TNF protein results in increased activity of CASP3 protein]]]; Zinc Acetate inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of ANXA5 protein]]]; Zinc Acetate promotes the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [TNF protein promotes the reaction [Linoleic Acid results in increased activity of CASP3 protein]]] CTD PMID:10617950 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 increases expression
multiple interactions		 EXP Linoleic Acid results in increased expression of VCAM1 mRNA
[Linoleic Acid co-treated with Polychlorinated Biphenyls] results in increased expression of VCAM1 protein; Linoleic Acid promotes the reaction [Polychlorinated Biphenyls results in increased expression of VCAM1 mRNA]; prolinedithiocarbamate inhibits the reaction [Linoleic Acid results in increased expression of VCAM1 mRNA]; Quercetin inhibits the reaction [Linoleic Acid results in increased expression of VCAM1 mRNA]		 CTD PMID:15051824 PMID:18155686 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,920...117,511,222 		JBrowse link
lipoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions EXP Thioctic Acid inhibits the reaction [Aldosterone results in increased activity of NFE2L2 protein] CTD PMID:24512358 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183 		JBrowse link
methoprene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPD1 glycerol-3-phosphate dehydrogenase 1 increases activity EXP Methoprene results in increased activity of GPD1 protein CTD PMID:15583048 NCBI chr 5:16,008,179...16,021,676
Ensembl chr 5:16,007,448...16,017,825 		JBrowse link
Monobutylphthalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIFM1 apoptosis inducing factor mitochondria associated 1 increases expression
multiple interactions		 EXP monobutyl phthalate results in increased expression of AIFM1 mRNA
Glycine inhibits the reaction [monobutyl phthalate results in increased expression of AIFM1 mRNA]		 CTD PMID:35839969 NCBI chr  X:106,676,596...106,708,290
Ensembl chr  X:106,670,520...106,708,317 		JBrowse link
G AMBRA1 autophagy and beclin 1 regulator 1 decreases expression EXP monobutyl phthalate results in decreased expression of AMBRA1 mRNA CTD PMID:35839969 NCBI chr 2:15,935,354...16,119,082
Ensembl chr 2:15,935,375...16,119,079 		JBrowse link
G AMPD3 adenosine monophosphate deaminase 3 increases expression EXP monobutyl phthalate results in increased expression of AMPD3 mRNA CTD PMID:35839969 NCBI chr 2:49,026,695...49,084,982
Ensembl chr 2:49,028,923...49,083,590 		JBrowse link
G ATG14 autophagy related 14 increases expression EXP monobutyl phthalate results in increased expression of ATG14 mRNA CTD PMID:35839969 NCBI chr 1:184,701,020...184,743,752
Ensembl chr 1:184,686,142...184,743,706 		JBrowse link
G ATRIP ATR interacting protein increases expression EXP monobutyl phthalate results in increased expression of ATRIP mRNA CTD PMID:35839969 NCBI chr13:31,159,849...31,178,716
Ensembl chr13:31,159,843...31,178,715 		JBrowse link
G AURKA aurora kinase A increases expression EXP monobutyl phthalate results in increased expression of AURKA mRNA CTD PMID:35839969 NCBI chr17:56,954,838...56,972,435 JBrowse link
G AVIL advillin decreases expression EXP monobutyl phthalate results in decreased expression of AVIL mRNA CTD PMID:35839969 NCBI chr 5:23,087,946...23,110,602
Ensembl chr 5:23,087,956...23,110,602 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 EXP monobutyl phthalate results in increased expression of BAX mRNA
Glycine inhibits the reaction [monobutyl phthalate results in increased expression of BAX mRNA]		 CTD PMID:35839969 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140 		JBrowse link
G CALD1 caldesmon 1 decreases expression EXP monobutyl phthalate results in decreased expression of CALD1 mRNA CTD PMID:35839969 NCBI chr18:14,267,955...14,486,641
Ensembl chr18:14,267,959...14,486,726 		JBrowse link
G CASP3 caspase 3 multiple interactions
increases expression		 EXP Glycine inhibits the reaction [monobutyl phthalate results in increased expression of and results in increased activity of CASP3 protein]; Glycine inhibits the reaction [monobutyl phthalate results in increased expression of CASP3 mRNA]; monobutyl phthalate results in increased expression of and results in increased activity of CASP3 protein CTD PMID:35839969 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G CAT catalase multiple interactions
decreases expression		 EXP Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of CAT mRNA] CTD PMID:35839969 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452 		JBrowse link
G CDC26 cell division cycle 26 decreases expression
multiple interactions		 EXP monobutyl phthalate results in decreased expression of CDC26 mRNA
Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of CDC26 mRNA]		 CTD PMID:35839969 NCBI chr 1:253,893,666...253,906,659
Ensembl chr 1:253,895,885...253,906,632 		JBrowse link
G CDH1 cadherin 1 increases expression EXP monobutyl phthalate results in increased expression of CDH1 mRNA CTD PMID:35839969 NCBI chr 6:18,075,487...18,155,986
Ensembl chr 6:18,075,480...18,155,986 		JBrowse link
G CFL1 cofilin 1 decreases expression EXP monobutyl phthalate results in decreased expression of CFL1 mRNA CTD PMID:35839969 NCBI chr 2:6,471,558...6,475,019
Ensembl chr 2:6,469,254...6,475,035 		JBrowse link
G EMC1 ER membrane protein complex subunit 1 decreases expression EXP monobutyl phthalate results in decreased expression of EMC1 mRNA CTD PMID:35839969 NCBI chr 6:77,723,374...77,747,780
Ensembl chr 6:77,718,849...77,747,771 		JBrowse link
G GABARAPL1 GABA type A receptor associated protein like 1 increases expression EXP monobutyl phthalate results in increased expression of GABARAPL1 mRNA CTD PMID:35839969 NCBI chr 5:61,758,127...61,767,427
Ensembl chr 5:61,758,130...61,767,601 		JBrowse link
G GRAMD2B GRAM domain containing 2B increases expression EXP monobutyl phthalate results in increased expression of GRAMD2B mRNA CTD PMID:35839969 NCBI chr 2:129,511,072...129,619,690
Ensembl chr 2:129,511,088...129,619,687 		JBrowse link
G HYOU1 hypoxia up-regulated 1 increases expression EXP monobutyl phthalate results in increased expression of HYOU1 mRNA CTD PMID:35839969 NCBI chr 9:46,264,929...46,277,056
Ensembl chr 9:46,264,933...46,276,995 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 affects localization EXP monobutyl phthalate affects the localization of ITPR1 protein CTD PMID:35839969 NCBI chr13:61,068,131...61,398,918
Ensembl chr13:61,068,126...61,398,912 		JBrowse link
G KAT14 lysine acetyltransferase 14 increases expression EXP monobutyl phthalate results in increased expression of KAT14 mRNA CTD PMID:35839969 NCBI chr17:26,484,957...26,521,532
Ensembl chr17:26,485,157...26,521,525 		JBrowse link
G LRPAP1 LDL receptor related protein associated protein 1 increases expression EXP monobutyl phthalate results in increased expression of LRPAP1 mRNA CTD PMID:35839969 NCBI chr 8:2,129,492...2,145,632
Ensembl chr 8:2,125,405...2,145,647 		JBrowse link
G MAP2K2 mitogen-activated protein kinase kinase 2 increases expression EXP monobutyl phthalate results in increased expression of MAP2K2 mRNA CTD PMID:35839969 NCBI chr 2:74,626,739...74,651,352
Ensembl chr 2:74,626,783...74,651,348 		JBrowse link
G MAP7D2 MAP7 domain containing 2 increases expression EXP monobutyl phthalate results in increased expression of MAP7D2 mRNA CTD PMID:35839969 NCBI chr  X:16,327,718...16,423,546
Ensembl chr  X:16,327,968...16,422,772 		JBrowse link
G MAPK7 mitogen-activated protein kinase 7 decreases expression EXP monobutyl phthalate results in decreased expression of MAPK7 mRNA CTD PMID:35839969 NCBI chr12:60,144,138...60,148,743
Ensembl chr12:60,144,136...60,158,739 		JBrowse link
G MFN1 mitofusin 1 decreases expression
multiple interactions		 EXP monobutyl phthalate results in decreased expression of MFN1 mRNA; monobutyl phthalate results in decreased expression of MFN1 protein
Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of MFN1 mRNA]; Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of MFN1 protein]		 CTD PMID:35839969 NCBI chr13:117,404,637...117,441,750
Ensembl chr13:117,404,699...117,442,481 		JBrowse link
G MFN2 mitofusin 2 decreases expression
multiple interactions		 EXP monobutyl phthalate results in decreased expression of MFN2 mRNA; monobutyl phthalate results in decreased expression of MFN2 protein
Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of MFN2 mRNA]; Glycine inhibits the reaction [monobutyl phthalate results in decreased expression of MFN2 protein]		 CTD PMID:35839969 NCBI chr 6:72,026,512...72,056,439
Ensembl chr 6:72,028,499...72,056,438 		JBrowse link
G MRS2 magnesium transporter MRS2 decreases expression EXP monobutyl phthalate results in decreased expression of MRS2 mRNA CTD PMID:35839969 NCBI chr 7:19,244,607...19,295,483
Ensembl chr 7:19,244,661...19,291,531 		JBrowse link
G NABP1 nucleic acid binding protein 1 decreases expression EXP monobutyl phthalate results in decreased expression of NABP1 mRNA CTD PMID:35839969 NCBI chr15:96,313,884...96,322,108
Ensembl chr15:96,313,903...96,335,191 		JBrowse link
G NEFH neurofilament heavy chain increases expression EXP monobutyl phthalate results in increased expression of NEFH mRNA CTD PMID:35839969 NCBI chr14:46,559,698...46,568,686
Ensembl chr14:46,559,860...46,568,088 		JBrowse link
G PHB2 prohibitin 2 increases expression EXP monobutyl phthalate results in increased expression of PHB2 mRNA CTD PMID:35839969 NCBI chr 5:63,751,566...63,756,480
Ensembl chr 5:63,751,558...63,756,478 		JBrowse link
G PSMD14 proteasome 26S subunit, non-ATPase 14 increases expression EXP monobutyl phthalate results in increased expression of PSMD14 mRNA CTD PMID:35839969 NCBI chr15:68,107,379...68,208,884
Ensembl chr15:68,162,532...68,208,883 		JBrowse link
G RPA3 replication protein A3 decreases expression EXP monobutyl phthalate results in decreased expression of RPA3 mRNA CTD PMID:35839969 NCBI chr 9:77,910,876...77,914,872
Ensembl chr 9:77,910,881...77,937,060 		JBrowse link
G SKA1 spindle and kinetochore associated complex subunit 1 increases expression EXP monobutyl phthalate results in increased expression of SKA1 mRNA CTD PMID:35839969 NCBI chr 1:99,976,354...99,993,492
Ensembl chr 1:99,976,485...99,993,462 		JBrowse link
G SLC30A9 solute carrier family 30 member 9 decreases expression EXP monobutyl phthalate results in decreased expression of SLC30A9 mRNA CTD PMID:35839969 NCBI chr 8:33,058,666...33,111,775
Ensembl chr 8:33,058,618...33,113,283 		JBrowse link
G SLC51A solute carrier family 51 member A decreases expression EXP monobutyl phthalate results in decreased expression of SLC51A mRNA CTD PMID:35839969 NCBI chr13:133,851,775...133,869,753
Ensembl chr13:133,851,776...133,869,753 		JBrowse link
G SMC1A structural maintenance of chromosomes 1A increases expression EXP monobutyl phthalate results in increased expression of SMC1A mRNA CTD PMID:35839969 NCBI chr  X:46,143,738...46,202,187
Ensembl chr  X:46,144,920...46,218,543 		JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 increases expression EXP monobutyl phthalate results in increased expression of SPTBN1 mRNA CTD PMID:35839969 NCBI chr 3:86,585,225...86,784,316
Ensembl chr 3:86,585,054...86,784,149 		JBrowse link
G STRIP2 striatin interacting protein 2 decreases expression EXP monobutyl phthalate results in decreased expression of STRIP2 mRNA CTD PMID:35839969 NCBI chr18:19,209,047...19,255,671
Ensembl chr18:19,209,051...19,255,676 		JBrowse link
G TUBA1B tubulin alpha 1b increases expression
multiple interactions		 EXP monobutyl phthalate results in increased expression of TUBA1B mRNA
Glycine inhibits the reaction [monobutyl phthalate results in increased expression of TUBA1B mRNA]		 CTD PMID:35839969 NCBI chr 5:15,150,229...15,153,620
Ensembl chr 5:15,149,099...15,153,620 		JBrowse link
G VDAC1 voltage dependent anion channel 1 affects localization EXP monobutyl phthalate affects the localization of VDAC1 protein CTD PMID:35839969 NCBI chr 2:136,302,188...136,334,461
Ensembl chr 2:136,302,191...136,396,301 		JBrowse link
O-acetyl-L-carnitine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC22A5 solute carrier family 22 member 5 increases uptake EXP SLC22A5 protein results in increased uptake of Acetylcarnitine CTD PMID:16826461 NCBI chr 2:134,660,741...134,847,575
Ensembl chr 2:134,660,808...134,686,219 		JBrowse link
phorbol 13-acetate 12-myristate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of CXCL8 protein CTD PMID:15912099 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861 		JBrowse link
G EDN1 endothelin 1 multiple interactions
increases expression		 EXP Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EDN1 protein] CTD PMID:17105827 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases phosphorylation EXP Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein CTD PMID:11325585 NCBI chr14:50,083,079...50,165,528
Ensembl chr14:50,082,896...50,165,513 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases phosphorylation EXP Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein CTD PMID:11325585 NCBI chr 3:18,291,444...18,299,410
Ensembl chr 3:18,291,445...18,299,567 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 increases phosphorylation EXP Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein CTD PMID:11325585 NCBI chr 2:78,338,466...78,399,108
Ensembl chr 2:78,338,376...78,399,100 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha decreases expression
multiple interactions		 EXP Tetradecanoylphorbol Acetate results in decreased expression of PPARA; Tetradecanoylphorbol Acetate results in decreased expression of PPARA protein
calphostin C promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of PPARA]; Tetradecanoylphorbol Acetate inhibits the reaction [Clofibrate results in increased expression of PPARA]		 CTD PMID:17105827 PMID:20568414 NCBI chr 5:3,302,755...3,321,091
Ensembl chr 5:3,300,741...3,364,239 		JBrowse link
G PRKCB protein kinase C beta decreases phosphorylation EXP Tetradecanoylphorbol Acetate results in decreased phosphorylation of PRKCB protein CTD PMID:15089098 NCBI chr 3:21,995,227...22,383,628
Ensembl chr 3:21,995,231...22,383,264 		JBrowse link
G PRKCD protein kinase C delta increases phosphorylation EXP Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCD protein CTD PMID:15089098 NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,610...35,323,356 		JBrowse link
G SELE selectin E increases expression EXP Tetradecanoylphorbol Acetate results in increased expression of SELE protein CTD PMID:16797888 NCBI chr 4:81,289,061...81,299,657 JBrowse link
G SELP selectin P increases expression EXP Tetradecanoylphorbol Acetate results in increased expression of SELP protein CTD PMID:16797888 NCBI chr 4:81,376,804...81,401,240
Ensembl chr 4:81,365,740...81,399,955 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 increases expression EXP Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein CTD PMID:16797888 NCBI chr 4:117,496,914...117,511,211
Ensembl chr 4:117,496,920...117,511,222 		JBrowse link
prostaglandin D2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOS3 nitric oxide synthase 3 multiple interactions
increases expression		 EXP BW A868C inhibits the reaction [Prostaglandin D2 results in increased expression of NOS3 mRNA]; Prostaglandin D2 inhibits the reaction [BW A868C results in decreased expression of NOS3 mRNA] CTD PMID:10644584 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943 		JBrowse link
prostaglandin E2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EDN1 endothelin 1 multiple interactions EXP [15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid co-treated with EDN1 protein] results in decreased chemical synthesis of Dinoprostone CTD PMID:16325014 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
G OXT oxytocin/neurophysin I prepropeptide increases abundance
multiple interactions
increases secretion		 EXP OXT protein results in increased abundance of Dinoprostone
Progesterone inhibits the reaction [OXT protein results in increased secretion of Dinoprostone]		 CTD PMID:16997130 PMID:21370738 NCBI chr17:32,605,586...32,606,449
Ensembl chr17:32,605,586...32,606,546 		JBrowse link
G PLA2G1B phospholipase A2 group IB increases chemical synthesis EXP PLA2G1B protein results in increased chemical synthesis of Dinoprostone CTD PMID:10706128 NCBI chr14:40,314,520...40,322,315
Ensembl chr14:40,314,520...40,322,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [Polychlorinated Biphenyls results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone; alpha-Linolenic Acid inhibits the reaction [[Polychlorinated Biphenyls results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; Linoleic Acid promotes the reaction [[Polychlorinated Biphenyls results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; Polychlorinated Biphenyls promotes the reaction [[Linoleic Acid results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; Resveratrol inhibits the reaction [PTGS2 protein results in increased chemical synthesis of Dinoprostone] CTD PMID:18155686 PMID:20825639 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
prostaglandin F2alpha term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CASP3 caspase 3 increases activity
multiple interactions
increases expression		 EXP Dinoprost results in increased activity of CASP3 protein
[epostane co-treated with Dinoprost] results in increased activity of CASP3 protein; Dinoprost promotes the reaction [epostane results in increased expression of CASP3 mRNA]; epostane promotes the reaction [Dinoprost results in increased expression of CASP3 mRNA]		 CTD PMID:20739670 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G CCL2 chemokine (C-C motif) ligand 2 increases expression
multiple interactions		 EXP Dinoprost results in increased expression of CCL2 mRNA
[Dinoprost co-treated with epostane] results in increased expression of CCL2 mRNA		 CTD PMID:21505051 NCBI chr12:40,798,109...40,800,013
Ensembl chr12:40,798,109...40,800,026 		JBrowse link
G CCL4 C-C motif chemokine ligand 4 increases expression
multiple interactions		 EXP Dinoprost results in increased expression of CCL4 mRNA
[Dinoprost co-treated with epostane] results in increased expression of CCL4 mRNA		 CTD PMID:21505051 NCBI chr12:39,479,190...39,480,511
Ensembl chr12:39,478,882...39,481,082 		JBrowse link
G CCL8 chemokine (C-C motif) ligand 8 increases expression
multiple interactions		 EXP Dinoprost results in increased expression of CCL8 mRNA
[Dinoprost co-treated with epostane] results in increased expression of CCL8 mRNA		 CTD PMID:21505051 NCBI chr12:40,740,468...40,741,970
Ensembl chr12:40,740,023...40,742,022 		JBrowse link
G CCR1 C-C motif chemokine receptor 1 multiple interactions
increases expression		 EXP epostane promotes the reaction [Dinoprost results in increased expression of CCR1 mRNA] CTD PMID:21505051 NCBI chr13:29,227,218...29,233,862
Ensembl chr13:29,227,222...29,233,960 		JBrowse link
G CCR2 C-C motif chemokine receptor 2 increases expression
multiple interactions		 EXP Dinoprost results in increased expression of CCR2 mRNA
epostane promotes the reaction [Dinoprost results in increased expression of CCR2 mRNA]		 CTD PMID:21505051 NCBI chr13:29,368,735...29,374,564
Ensembl chr13:29,285,012...29,376,343 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 increases expression
multiple interactions		 EXP Dinoprost results in increased expression of CCR5 mRNA
epostane promotes the reaction [Dinoprost results in increased expression of CCR5 mRNA]		 CTD PMID:21505051 NCBI chr13:29,382,383...29,387,902
Ensembl chr13:29,383,303...29,387,895 		JBrowse link
G CXCL2 chemokine (C-X-C motif) ligand 2 multiple interactions
increases expression		 EXP [Dinoprost co-treated with epostane] results in increased expression of CXCL2 mRNA
Dinoprost results in increased expression of CXCL2 mRNA		 CTD PMID:21505051 NCBI chr 8:70,157,253...70,159,145
Ensembl chr 8:70,157,214...70,159,138 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 increases expression
multiple interactions		 EXP Dinoprost results in increased expression of CXCL8 mRNA
[Dinoprost co-treated with epostane] results in increased expression of CXCL8 mRNA		 CTD PMID:21505051 NCBI chr 8:69,932,646...69,935,861
Ensembl chr 8:69,932,643...69,935,861 		JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 multiple interactions
increases expression		 EXP epostane promotes the reaction [Dinoprost results in increased expression of CXCR2 mRNA] CTD PMID:21505051 NCBI chr15:120,219,657...120,230,203 JBrowse link
G CYP19A3 cytochrome P450 19A3 multiple interactions EXP [epostane co-treated with Dinoprost] results in increased expression of CYP19A1 mRNA CTD PMID:20739670 NCBI chr 1:120,476,890...120,556,103
Ensembl chr 1:120,367,667...120,695,899 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide increases secretion
multiple interactions		 EXP GHRL protein results in increased secretion of Dinoprost
STAT1 protein inhibits the reaction [GHRL protein results in increased secretion of Dinoprost]		 CTD PMID:19528263 NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,445,992...66,452,917 		JBrowse link
G NFKBIA NFKB inhibitor alpha increases phosphorylation EXP Dinoprost results in increased phosphorylation of NFKBIA protein CTD PMID:21505051 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,507,822...64,511,277 		JBrowse link
G OXT oxytocin/neurophysin I prepropeptide multiple interactions
increases abundance
increases secretion		 EXP Progesterone inhibits the reaction [OXT protein results in increased abundance of Dinoprost]; Progesterone inhibits the reaction [OXT protein results in increased secretion of Dinoprost] CTD PMID:16997130 PMID:21370738 NCBI chr17:32,605,586...32,606,449
Ensembl chr17:32,605,586...32,606,546 		JBrowse link
G PLA2G1B phospholipase A2 group IB multiple interactions EXP [epostane co-treated with Dinoprost] results in increased expression of PLA2G1B mRNA CTD PMID:20739670 NCBI chr14:40,314,520...40,322,315
Ensembl chr14:40,314,520...40,322,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [epostane co-treated with Dinoprost] results in increased expression of PTGS2 mRNA CTD PMID:20739670 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 multiple interactions
increases secretion		 EXP STAT1 protein inhibits the reaction [GHRL protein results in increased secretion of Dinoprost]
STAT1 protein results in increased secretion of Dinoprost		 CTD PMID:19528263 NCBI chr15:95,593,201...95,646,324
Ensembl chr15:95,593,211...95,646,260 		JBrowse link
prostaglandin J2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 multiple interactions EXP 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased expression of CYP17A1 mRNA] CTD PMID:11889176 NCBI chr14:113,805,616...113,820,445
Ensembl chr14:113,805,611...113,812,041 		JBrowse link
G INS insulin multiple interactions EXP 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Androstenedione]; 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Testosterone]; 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased expression of CYP17A1 mRNA] CTD PMID:11889176 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841 		JBrowse link
G LHB luteinizing hormone subunit beta multiple interactions EXP 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Androstenedione]; 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased abundance of Testosterone]; 9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased expression of CYP17A1 mRNA] CTD PMID:11889176 NCBI chr 6:54,263,574...54,269,286
Ensembl chr 6:54,263,576...54,271,086 		JBrowse link
simvastatin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
decreases expression		 EXP Simvastatin promotes the reaction [Ezetimibe results in increased expression of HMGCR mRNA]
Simvastatin results in decreased expression of HMGCR mRNA		 CTD PMID:17130282 PMID:19343539 NCBI chr 2:84,380,245...84,401,117
Ensembl chr 2:84,380,224...84,402,957 		JBrowse link
G LDLR low density lipoprotein receptor multiple interactions
increases expression		 EXP Simvastatin promotes the reaction [Ezetimibe results in increased expression of LDLR mRNA]
Simvastatin results in increased expression of LDLR mRNA		 CTD PMID:17130282 NCBI chr 2:69,828,348...69,864,823
Ensembl chr 2:69,828,332...69,864,827 		JBrowse link
G NPC1L1 NPC1 like intracellular cholesterol transporter 1 multiple interactions EXP Simvastatin promotes the reaction [Ezetimibe results in increased expression of NPC1L1 mRNA] CTD PMID:17130282 NCBI chr18:50,726,854...50,757,676
Ensembl chr18:50,726,922...50,757,649 		JBrowse link
G NR4A3 nuclear receptor subfamily 4 group A member 3 decreases expression EXP Simvastatin results in decreased expression of NR4A3 mRNA CTD PMID:16005304 NCBI chr 1:241,569,867...241,611,735
Ensembl chr 1:241,570,010...241,611,727 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 multiple interactions EXP [Ezetimibe co-treated with Simvastatin] results in increased expression of SREBF1 mRNA CTD PMID:17130282 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,267 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 multiple interactions EXP Simvastatin promotes the reaction [Ezetimibe results in increased expression of SREBF2 mRNA] CTD PMID:17130282 NCBI chr 5:6,719,484...6,784,724
Ensembl chr 5:6,719,490...6,784,671 		JBrowse link
sulprostone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOS3 nitric oxide synthase 3 multiple interactions EXP sulprostone inhibits the reaction [Ibuprofen results in decreased expression of NOS3 mRNA] CTD PMID:10525081 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943 		JBrowse link
thapsigargin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HSP90B1 heat shock protein 90 beta family member 1 increases expression
multiple interactions
decreases expression
increases cleavage		 EXP Thapsigargin results in increased expression of HSP90B1 protein
PD 150606 inhibits the reaction [Thapsigargin results in increased cleavage of HSP90B1 protein]
Thapsigargin results in decreased expression of HSP90B1 protein		 CTD PMID:16759985 PMID:16920763 PMID:17416481 NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 increases expression EXP Thapsigargin results in increased expression of HSPA5 protein CTD PMID:16759985 PMID:16920763 PMID:17416481 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5053
    chemical entity 5053
      atom 5044
        nonmetal atom 5008
          carbon atom 4928
            organic molecular entity 4928
              lipid 4410
                fatty acid 130
                  2,3,4-saturated fatty acid 0
                  2,3-saturated fatty acid 0
                  FAHFA + 0
                  N-(fatty acyl)-L-alpha-amino acid + 0
                  branched-chain fatty acid + 35
                  cis-fatty acid 0
                  cyclic fatty acid + 23
                  deuterated fatty acid + 0
                  fatty acid 10:2 0
                  fatty acid 12:0 0
                  fatty acid 13:0 0
                  fatty acid 14:0 0
                  fatty acid 14:4 0
                  fatty acid 15:0 0
                  fatty acid 16:0 + 0
                  fatty acid 16:1 0
                  fatty acid 17:0 0
                  fatty acid 17:1 0
                  fatty acid 18:0 0
                  fatty acid 18:1 + 0
                  fatty acid 18:2 + 8
                  fatty acid 18:3-omega-3omega-6 0
                  fatty acid 19:0 0
                  fatty acid 20:0 0
                  fatty acid 20:1 + 0
                  fatty acid 20:2 0
                  fatty acid 20:3-omega-3omega-6 0
                  fatty acid 20:3-omega-9 0
                  fatty acid 20:4-omega-6 0
                  fatty acid 20:5 + 0
                  fatty acid 20:5-omega-3 0
                  fatty acid 21:0 0
                  fatty acid 22:0 0
                  fatty acid 22:2 0
                  fatty acid 22:3 0
                  fatty acid 22:5-omega-3 0
                  fatty acid 22:5-omega-6 0
                  fatty acid 22:6 + 0
                  fatty acid 23:0 0
                  fatty acid 24:0 0
                  fatty acid 24:1 0
                  fatty acid 24:2 0
                  fatty acid 26:0 + 0
                  fatty acid 7:0 0
                  fatty acid 8:0 0
                  fatty acid 9:0 0
                  fatty acid derivative + 91
                  fatty acid ester + 21
                  fatty acid ethyl ester + 0
                  fatty acid-taurine conjugate + 0
                  fatty acyl-AMP + 0
                  fatty amide + 3
                  halo fatty acid + 0
                  hydroperoxy fatty acid + 0
                  hydroxy fatty acid + 1
                  lecithin 0
                  long-chain fatty acid + 37
                  maradolipid 0
                  medium-chain fatty acid + 1
                  nitrogen-containing fatty acid + 0
                  oxa fatty acid + 0
                  oxo fatty acid + 1
                  oxylipin + 0
                  royal jelly 0
                  saturated fatty acid + 81
                  short-chain fatty acid + 52
                  straight-chain fatty acid + 40
                  thia fatty acid + 1
                  thio-fatty acid + 0
                  trans-fatty acid 0
                  unsaturated fatty acid + 10
                  very long-chain fatty acid + 2
                  wax ester + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5053
    subatomic particle 5044
      composite particle 5044
        hadron 5044
          baryon 5044
            nucleon 5044
              atomic nucleus 5044
                atom 5044
                  main group element atom 5015
                    p-block element atom 5012
                      carbon group element atom 4929
                        carbon atom 4928
                          organic molecular entity 4928
                            heteroorganic entity 4770
                              organochalcogen compound 4732
                                organooxygen compound 4694
                                  carbon oxoacid 368
                                    carboxylic acid 364
                                      monocarboxylic acid 206
                                        fatty acid 130
                                          2,3,4-saturated fatty acid 0
                                          2,3-saturated fatty acid 0
                                          FAHFA + 0
                                          N-(fatty acyl)-L-alpha-amino acid + 0
                                          branched-chain fatty acid + 35
                                          cis-fatty acid 0
                                          cyclic fatty acid + 23
                                          deuterated fatty acid + 0
                                          fatty acid 10:2 0
                                          fatty acid 12:0 0
                                          fatty acid 13:0 0
                                          fatty acid 14:0 0
                                          fatty acid 14:4 0
                                          fatty acid 15:0 0
                                          fatty acid 16:0 + 0
                                          fatty acid 16:1 0
                                          fatty acid 17:0 0
                                          fatty acid 17:1 0
                                          fatty acid 18:0 0
                                          fatty acid 18:1 + 0
                                          fatty acid 18:2 + 8
                                          fatty acid 18:3-omega-3omega-6 0
                                          fatty acid 19:0 0
                                          fatty acid 20:0 0
                                          fatty acid 20:1 + 0
                                          fatty acid 20:2 0
                                          fatty acid 20:3-omega-3omega-6 0
                                          fatty acid 20:3-omega-9 0
                                          fatty acid 20:4-omega-6 0
                                          fatty acid 20:5 + 0
                                          fatty acid 20:5-omega-3 0
                                          fatty acid 21:0 0
                                          fatty acid 22:0 0
                                          fatty acid 22:2 0
                                          fatty acid 22:3 0
                                          fatty acid 22:5-omega-3 0
                                          fatty acid 22:5-omega-6 0
                                          fatty acid 22:6 + 0
                                          fatty acid 23:0 0
                                          fatty acid 24:0 0
                                          fatty acid 24:1 0
                                          fatty acid 24:2 0
                                          fatty acid 26:0 + 0
                                          fatty acid 7:0 0
                                          fatty acid 8:0 0
                                          fatty acid 9:0 0
                                          fatty acid derivative + 91
                                          fatty acid ester + 21
                                          fatty acid ethyl ester + 0
                                          fatty acid-taurine conjugate + 0
                                          fatty acyl-AMP + 0
                                          fatty amide + 3
                                          halo fatty acid + 0
                                          hydroperoxy fatty acid + 0
                                          hydroxy fatty acid + 1
                                          lecithin 0
                                          long-chain fatty acid + 37
                                          maradolipid 0
                                          medium-chain fatty acid + 1
                                          nitrogen-containing fatty acid + 0
                                          oxa fatty acid + 0
                                          oxo fatty acid + 1
                                          oxylipin + 0
                                          royal jelly 0
                                          saturated fatty acid + 81
                                          short-chain fatty acid + 52
                                          straight-chain fatty acid + 40
                                          thia fatty acid + 1
                                          thio-fatty acid + 0
                                          trans-fatty acid 0
                                          unsaturated fatty acid + 10
                                          very long-chain fatty acid + 2
                                          wax ester + 0
paths to the root