SELE (selectin E) - Rat Genome Database
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Gene: SELE (selectin E) Sus scrofa
Analyze
Symbol: SELE
Name: selectin E
RGD ID: 14293223
Description: ENCODES a protein that exhibits oligosaccharide binding (ortholog); phospholipase binding (ortholog); sialic acid binding (ortholog); INVOLVED IN actin filament-based process (ortholog); activation of phospholipase C activity (ortholog); heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (ortholog); PARTICIPATES IN eicosanoid signaling pathway; ASSOCIATED WITH 1q24 Deletion Syndrome (ortholog); allergic contact dermatitis (ortholog); arthritis (ortholog); FOUND IN caveola (ortholog); clathrin-coated pit (ortholog); cortical cytoskeleton (ortholog); INTERACTS WITH 3,3',4,4'-tetrachlorobiphenyl; aluminium oxide; bis(2-chloroethyl) sulfide
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CD62 antigen-like family member E; E-selectin; ELAM-1; endothelial leukocyte adhesion molecule 1; LECAM2; leukocyte-endothelial cell adhesion molecule 2; selectin E (endothelial adhesion molecule 1)
Orthologs:
Homo sapiens (human) : SELE (selectin E)  HGNC  Alliance
Mus musculus (house mouse) : Sele (selectin, endothelial cell)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sele (selectin E)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sele (selectin E)
Pan paniscus (bonobo/pygmy chimpanzee) : SELE (selectin E)
Canis lupus familiaris (dog) : SELE (selectin E)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sele (selectin E)
Chlorocebus sabaeus (African green monkey) : SELE (selectin E)
Heterocephalus glaber (naked mole-rat) : Sele (selectin E)
more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1481,289,061 - 81,299,657 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2488,914,255 - 88,924,371 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:7516159   PMID:7526854   PMID:8918234   PMID:15050129   PMID:24336934  


Genomics

Comparative Map Data
SELE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1481,289,061 - 81,299,657 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2488,914,255 - 88,924,371 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SELE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1169,722,640 - 169,764,705 (-)EnsemblGRCh38hg38GRCh38
GRCh381169,722,640 - 169,734,079 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371169,691,781 - 169,703,220 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361167,958,406 - 167,969,803 (-)NCBINCBI36hg18NCBI36
Build 341166,423,439 - 166,434,837NCBI
Celera1142,801,587 - 142,813,012 (-)NCBI
Cytogenetic Map1q24.2NCBI
HuRef1140,914,126 - 140,925,551 (-)NCBIHuRef
CHM1_11171,113,936 - 171,125,374 (-)NCBICHM1_1
Sele
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391163,867,200 - 163,886,056 (+)NCBI
GRCm381164,039,614 - 164,058,487 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1164,048,234 - 164,057,677 (+)EnsemblGRCm38mm10GRCm38
MGSCv371165,978,365 - 165,987,808 (+)NCBIGRCm37mm9NCBIm37
MGSCv361165,884,909 - 165,894,352 (+)NCBImm8
Celera1166,489,844 - 166,499,312 (+)NCBICelera
Cytogenetic Map1H2.2NCBI
cM Map171.35NCBI
Sele
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01382,355,234 - 82,365,323 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1382,355,471 - 82,365,341 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01387,234,842 - 87,244,746 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41379,813,455 - 79,822,845 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11379,827,642 - 79,837,033 (+)NCBI
Celera1376,136,932 - 76,146,318 (+)NCBICelera
Cytogenetic Map13q23NCBI
Sele
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554627,564,437 - 7,575,297 (+)NCBIChiLan1.0ChiLan1.0
SELE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11148,927,333 - 148,938,781 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1148,930,437 - 148,938,313 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01145,205,684 - 145,217,143 (-)NCBIMhudiblu_PPA_v0panPan3
SELE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl728,888,197 - 28,898,786 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1728,888,503 - 28,898,787 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Sele
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493648116,915,203 - 16,921,840 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SELE
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl2559,322,913 - 59,330,668 (+)Ensembl
ChlSab1.12559,305,610 - 59,333,789 (+)NCBI
Sele
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248267,624,852 - 7,635,330 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 2 1 2 1
Below cutoff 8 2 2 4 1 7 2 1

Sequence


Reference Sequences
RefSeq Acc Id: NM_214268   ⟹   NP_999433
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1481,289,173 - 81,298,969 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013996784   ⟹   XP_013852238
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1481,289,061 - 81,299,657 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_999433 (Get FASTA)   NCBI Sequence Viewer  
  XP_013852238 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA21541 (Get FASTA)   NCBI Sequence Viewer  
  AAA61545 (Get FASTA)   NCBI Sequence Viewer  
  AAC48680 (Get FASTA)   NCBI Sequence Viewer  
  P98110 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013852238   ⟸   XM_013996784
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_999433   ⟸   NM_214268
- Peptide Label: precursor
- Sequence:
Protein Domains
C-type lectin   EGF-like   Sushi


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000006286 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015013883 UniProtKB/Swiss-Prot
  ENSSSCG00030050466 UniProtKB/Swiss-Prot
  ENSSSCG00050068229 UniProtKB/Swiss-Prot
  ENSSSCG00060068755 UniProtKB/Swiss-Prot
  ENSSSCG00065003630 UniProtKB/Swiss-Prot
  ENSSSCG00070020072 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000006699 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00015007307 UniProtKB/Swiss-Prot
  ENSSSCP00030032085 UniProtKB/Swiss-Prot
  ENSSSCP00050040160 UniProtKB/Swiss-Prot
  ENSSSCP00060040635 UniProtKB/Swiss-Prot
  ENSSSCP00065002143 UniProtKB/Swiss-Prot
  ENSSSCP00070033432 UniProtKB/TrEMBL
  ENSSSCP00070033521 UniProtKB/TrEMBL
  ENSSSCP00070033571 UniProtKB/TrEMBL
  ENSSSCP00070033588 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000006887 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00015018437 UniProtKB/Swiss-Prot
  ENSSSCT00030070356 UniProtKB/Swiss-Prot
  ENSSSCT00050093099 UniProtKB/Swiss-Prot
  ENSSSCT00060093921 UniProtKB/Swiss-Prot
  ENSSSCT00065004958 UniProtKB/Swiss-Prot
  ENSSSCT00070039911 UniProtKB/TrEMBL
  ENSSSCT00070040014 UniProtKB/TrEMBL
  ENSSSCT00070040066 UniProtKB/TrEMBL
  ENSSSCT00070040087 UniProtKB/TrEMBL
Gene3D-CATH 3.10.100.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro C-type_lectin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C-type_lectin-like/link_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C-type_lectin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CTDL_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Selectin_CTLD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Selectin_superfamily UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sushi/SCR/CCP_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sushi_SCR_CCP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397508 UniProtKB/Swiss-Prot
NCBI Gene SELE ENTREZGENE
Pfam Lectin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sushi UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS SELECTIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE C_TYPE_LECTIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C_TYPE_LECTIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SUSHI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CCP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CLECT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56436 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57535 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Ssc.16297 ENTREZGENE
UniProt A0A4X1UVY9_PIG UniProtKB/TrEMBL
  A0A4X1UX95_PIG UniProtKB/TrEMBL
  A0A4X1UXM9_PIG UniProtKB/TrEMBL
  A0A4X1UXS5_PIG UniProtKB/TrEMBL
  F1RSC6_PIG UniProtKB/TrEMBL
  LYAM2_PIG UniProtKB/Swiss-Prot, ENTREZGENE