HSP90B1 (heat shock protein 90 beta family member 1) - Rat Genome Database

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Gene: HSP90B1 (heat shock protein 90 beta family member 1) Sus scrofa
Analyze
Symbol: HSP90B1
Name: heat shock protein 90 beta family member 1
RGD ID: 14211492
Description: ENCODES a protein that exhibits ATP binding (inferred); ATP hydrolysis activity (inferred); ATP-dependent protein folding chaperone (inferred); INVOLVED IN actin rod assembly (ortholog); cellular response to ATP (ortholog); cellular response to manganese ion (ortholog); PARTICIPATES IN codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; etoposide pharmacodynamics pathway; ASSOCIATED WITH Prostatic Neoplasms (ortholog); FOUND IN endoplasmic reticulum chaperone complex (ortholog); smooth endoplasmic reticulum (ortholog); sperm plasma membrane (ortholog); INTERACTS WITH cadmium atom; cadmium dichloride; cobalt dichloride
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 94 kDa glucose-regulated protein; 98 kDa protein kinase; endoplasmin; Gp96; gp96 homolog; GRP-94; GRP94; heat shock protein 90 kDa beta member 1; heat shock protein 90kDa beta (Grp94), member 1; PPK 98; ppk98; TRA1; tumor rejection antigen (gp96) 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl580,511,506 - 80,530,991 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1580,511,513 - 80,531,016 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2584,016,174 - 84,083,931 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:7957217   PMID:9407008   PMID:10101271   PMID:14681463   PMID:15236592   PMID:16731965   PMID:17145712  


Genomics

Comparative Map Data
HSP90B1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl580,511,506 - 80,530,991 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1580,511,513 - 80,531,016 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2584,016,174 - 84,083,931 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HSP90B1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812103,930,410 - 103,947,926 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl12103,930,107 - 103,953,931 (+)EnsemblGRCh38hg38GRCh38
GRCh3712104,324,188 - 104,341,704 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612102,848,319 - 102,865,833 (+)NCBINCBI36hg18NCBI36
Build 3412102,826,655 - 102,844,170NCBI
Celera12103,987,945 - 104,005,473 (+)NCBI
Cytogenetic Map12q23.3NCBI
HuRef12101,383,834 - 101,401,444 (+)NCBIHuRef
CHM1_112104,290,083 - 104,307,660 (+)NCBICHM1_1
T2T-CHM13v2.012103,892,110 - 103,909,638 (+)NCBI
Hsp90b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391086,526,705 - 86,541,308 (-)NCBIGRCm39mm39
GRCm39 Ensembl1086,526,073 - 86,541,373 (-)Ensembl
GRCm381086,690,841 - 86,705,444 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1086,690,209 - 86,705,509 (-)EnsemblGRCm38mm10GRCm38
MGSCv371086,153,586 - 86,168,189 (-)NCBIGRCm37mm9NCBIm37
MGSCv361086,120,640 - 86,135,243 (-)NCBImm8
Celera1088,669,594 - 88,684,200 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1043.05NCBI
Hsp90b1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2721,110,431 - 21,124,762 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl721,110,457 - 21,124,788 (-)Ensembl
Rnor_6.0727,226,570 - 27,240,533 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl727,226,569 - 27,240,533 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0727,345,730 - 27,359,757 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4723,332,986 - 23,347,525 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1723,353,261 - 23,367,796 (-)NCBI
Celera718,290,242 - 18,304,551 (-)NCBICelera
Cytogenetic Map7q13NCBI
Hsp90b1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540538,629,691 - 38,645,202 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540538,629,691 - 38,645,202 (+)NCBIChiLan1.0ChiLan1.0
HSP90B1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.112104,901,997 - 104,919,592 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12104,901,997 - 104,919,329 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v012101,506,845 - 101,524,407 (+)NCBIMhudiblu_PPA_v0panPan3
HSP90B1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11542,456,793 - 42,474,122 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1542,456,764 - 42,579,311 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1542,826,278 - 42,843,622 (+)NCBI
ROS_Cfam_1.01543,114,295 - 43,131,887 (+)NCBI
ROS_Cfam_1.0 Ensembl1543,114,231 - 43,235,108 (+)Ensembl
UMICH_Zoey_3.11542,380,743 - 42,398,025 (+)NCBI
UNSW_CanFamBas_1.01542,479,226 - 42,496,568 (+)NCBI
UU_Cfam_GSD_1.01542,750,406 - 42,767,726 (+)NCBI
Hsp90b1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494517,503,494 - 17,517,769 (-)NCBI
SpeTri2.0NW_00493649210,513,908 - 10,528,281 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSP90B1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11199,119,268 - 99,139,988 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1199,119,224 - 99,139,722 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037145,859,568 - 145,877,331 (-)NCBIVero_WHO_p1.0
Hsp90b1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247504,737,894 - 4,752,221 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247504,738,563 - 4,752,227 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High 1
Medium 10 4 3 4 2 23 2 3 3
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000000926   ⟹   ENSSSCP00000000906
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl580,511,506 - 80,530,991 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000047341   ⟹   ENSSSCP00000042515
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl580,511,506 - 80,530,991 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000101408   ⟹   ENSSSCP00000077198
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl580,511,506 - 80,530,991 (-)Ensembl
RefSeq Acc Id: NM_214103   ⟹   NP_999268
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1580,512,183 - 80,530,862 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021091129   ⟹   XP_020946788
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1580,511,513 - 80,531,016 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_999268 (Get FASTA)   NCBI Sequence Viewer  
  XP_020946788 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA53948 (Get FASTA)   NCBI Sequence Viewer  
  CAA62352 (Get FASTA)   NCBI Sequence Viewer  
  CAA70347 (Get FASTA)   NCBI Sequence Viewer  
  Q29092 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020946788   ⟸   XM_021091129
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_999268   ⟸   NM_214103
- Peptide Label: precursor
- UniProtKB: Q29092 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSSSCP00000000906   ⟸   ENSSSCT00000000926
RefSeq Acc Id: ENSSSCP00000042515   ⟸   ENSSSCT00000047341
RefSeq Acc Id: ENSSSCP00000077198   ⟸   ENSSSCT00000101408
Protein Domains
HATPase_c


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000000849 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005037852 UniProtKB/TrEMBL
  ENSSSCG00030034427 UniProtKB/TrEMBL
  ENSSSCG00040032318 UniProtKB/TrEMBL
  ENSSSCG00045015245 UniProtKB/TrEMBL
  ENSSSCG00055012322 UniProtKB/TrEMBL
  ENSSSCG00060065937 UniProtKB/TrEMBL
  ENSSSCG00065030636 UniProtKB/TrEMBL
  ENSSSCG00070006856 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000000906 ENTREZGENE
  ENSSSCP00000000906.4 UniProtKB/TrEMBL
  ENSSSCP00000042515.2 UniProtKB/TrEMBL
  ENSSSCP00005037829.1 UniProtKB/TrEMBL
  ENSSSCP00030021469.1 UniProtKB/TrEMBL
  ENSSSCP00040018258.1 UniProtKB/TrEMBL
  ENSSSCP00045017839.1 UniProtKB/TrEMBL
  ENSSSCP00055019218.1 UniProtKB/TrEMBL
  ENSSSCP00060039017.1 UniProtKB/TrEMBL
  ENSSSCP00065017573.1 UniProtKB/TrEMBL
  ENSSSCP00070010877.1 UniProtKB/TrEMBL
  ENSSSCP00070010887.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000000926 ENTREZGENE
  ENSSSCT00000000926.4 UniProtKB/TrEMBL
  ENSSSCT00000047341.2 UniProtKB/TrEMBL
  ENSSSCT00005061195.1 UniProtKB/TrEMBL
  ENSSSCT00030047650.1 UniProtKB/TrEMBL
  ENSSSCT00040043501.1 UniProtKB/TrEMBL
  ENSSSCT00045025856.1 UniProtKB/TrEMBL
  ENSSSCT00055024235.1 UniProtKB/TrEMBL
  ENSSSCT00060090080.1 UniProtKB/TrEMBL
  ENSSSCT00065041453.1 UniProtKB/TrEMBL
  ENSSSCT00070013202.1 UniProtKB/TrEMBL
  ENSSSCT00070013214.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.790 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.565.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro HATPase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HATPase_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Heat_shock_protein_90_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HSP90_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hsp90_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hsp90_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S5_D2-typ_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:397191 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene HSP90B1 ENTREZGENE
PANTHER PTHR11528 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HATPase_c UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HSP90 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF Hsp90 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS HEATSHOCK90 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ER_TARGET UniProtKB/Swiss-Prot
  HSP90 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART HATPase_c UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF110942 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54211 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55874 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A287AFA5_PIG UniProtKB/TrEMBL
  A0A4X1T658_PIG UniProtKB/TrEMBL
  A0A4X1T7Z2_PIG UniProtKB/TrEMBL
  A0A8D0KEJ4_PIG UniProtKB/TrEMBL
  ENPL_PIG UniProtKB/Swiss-Prot
  F1SRK6_PIG UniProtKB/TrEMBL
  Q29092 ENTREZGENE
UniProt Secondary O19070 UniProtKB/Swiss-Prot
  Q29091 UniProtKB/Swiss-Prot
VGNC ID VGNC:103290 ENTREZGENE