RPA3 (replication protein A3) - Rat Genome Database

Name: RPA3
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: RPA3 (replication protein A3) Sus scrofa

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Symbol:

RPA3

Name:

replication protein A3

RGD ID:

14076138

Description:

ENCODES a protein that exhibits damaged DNA binding (inferred); DNA binding (inferred); single-stranded DNA binding (inferred); INVOLVED IN regulation of cell population proliferation (ortholog); regulation of mitotic cell cycle (ortholog); PARTICIPATES IN mismatch repair pathway; nucleotide excision repair pathway; FOUND IN DNA replication factor A complex (ortholog); INTERACTS WITH deoxynivalenol; Monobutylphthalate

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

replication protein A 14 kDa subunit

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RPA3 (replication protein A3)	HGNC	EggNOG, Ensembl, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Rpa3 (replication protein A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Rpa3 (replication protein A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Rpa3 (replication protein A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RPA3 (replication protein A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RPA3 (replication protein A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Rpa3 (replication protein A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RPA3 (replication protein A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Rpa3 (replication protein A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	77,910,881 - 77,937,060 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	77,910,876 - 77,914,872 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

deoxynivalenol (EXP)

Monobutylphthalate (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

base-excision repair (IEA)

DNA recombination (IEA)

DNA repair (IEA)

DNA replication (IEA)

double-strand break repair via homologous recombination (IEA)

mismatch repair (IEA)

nucleotide-excision repair (IEA)

regulation of cell population proliferation (IEA,ISO)

regulation of mitotic cell cycle (IEA,ISO)

Cellular Component

DNA replication factor A complex (IEA,ISO)

nuclear lumen (IEA)

nucleus (IEA)

Molecular Function

damaged DNA binding (IEA)

DNA binding (IEA)

protein binding (ISO)

single-stranded DNA binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

mismatch repair pathway (ISO)

nucleotide excision repair pathway (ISO)

References

Additional References at PubMed

PMID:15679890	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

RPA3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	77,910,881 - 77,937,060 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	77,910,876 - 77,914,872 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

RPA3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	7,636,518 - 7,718,607 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	7,636,518 - 7,718,607 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	7,676,149 - 7,758,238 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	7,643,100 - 7,724,763 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	7	7,449,816 - 7,531,478	NCBI
Celera	7	7,644,982 - 7,725,987 (-)	NCBI		Celera
Cytogenetic Map	7	p21.3	NCBI
HuRef	7	7,525,171 - 7,607,577 (-)	NCBI		HuRef
CHM1_1	7	7,676,293 - 7,757,838 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	7	7,754,317 - 7,837,139 (-)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	7,723,782 - 7,804,410 (-)	NCBI

Rpa3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	8,255,936 - 8,259,141 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	8,255,936 - 8,259,173 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	8,255,936 - 8,259,141 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	8,255,936 - 8,259,173 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	8,205,936 - 8,209,141 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	8,205,937 - 8,209,113 (-)	NCBI		MGSCv36	mm8
Celera	6	8,397,638 - 8,400,833 (-)	NCBI		Celera
Cytogenetic Map	6	A1	NCBI
cM Map	6	3.53	NCBI

Rpa3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	37,270,966 - 37,273,997 (-)	NCBI		GRCr8
mRatBN7.2	4	36,304,649 - 36,307,755 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	36,304,651 - 36,307,709 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	41,272,230 - 41,275,262 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	37,198,431 - 37,201,463 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	35,609,727 - 35,612,758 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	34,279,320 - 34,282,351 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	34,279,320 - 34,282,351 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	34,139,498 - 34,142,529 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	33,304,334 - 33,307,365 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	33,422,871 - 33,425,905 (-)	NCBI
Celera	4	31,808,230 - 31,811,261 (-)	NCBI		Celera
Cytogenetic Map	4	q21	NCBI

Rpa3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955432	14,723,751 - 14,727,290 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955432	14,723,933 - 14,727,356 (-)	NCBI	ChiLan1.0	ChiLan1.0

RPA3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	12,536,575 - 12,540,340 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	60,861,290 - 60,864,770 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	8,361,623 - 8,365,098 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	7,713,632 - 7,794,199 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	7,713,629 - 7,717,169 (-)	Ensembl	panpan1.1		panPan2

RPA3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	14	23,230,447 - 23,234,554 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	2,893,352 - 2,893,717 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	14	22,805,480 - 22,809,588 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	14	23,045,005 - 23,049,117 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	14	23,197,309 - 23,201,240 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	14	22,930,101 - 22,934,209 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	14	23,187,728 - 23,191,835 (-)	NCBI		UU_Cfam_GSD_1.0

Rpa3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	36,592,667 - 36,596,130 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936585	2,266,706 - 2,272,259 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936585	2,267,113 - 2,270,635 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RPA3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	50,570,027 - 50,574,270 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	50,570,751 - 50,574,216 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666042	53,812,402 - 53,816,643 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rpa3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624813	5,247,033 - 5,253,413 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624813	5,248,794 - 5,252,264 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in RPA3
62 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
10	4	23	3	2	5	14	12	23	3	6	3

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021102423	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000070	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY610313	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01018486	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000027813 ⟹ ENSSSCP00000022985

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	9	77,910,881 - 77,937,060 (-)	Ensembl

RefSeq Acc Id:

XM_021102423 ⟹ XP_020958082

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	9	77,910,876 - 77,914,872 (-)	NCBI

Sequence:

show sequence

CATCCTAGCCTTCTTCGCCGGCGGAGACAGCGGGACTGTGATCGAGATTTCCGCGCGTTTGATT
GGCGGAGCGAGAGTGCTGGTCTCCGCGGATTGGTGCCGGGGAAATCCGCCCCGAAGACGTCTGC
CGAGCTCAAGGTTTCAGTTGTCGGCTTGTTTCCCGCCATCTGTCGGTCCTGCATTGCAGTTATG
GTGGACGTGATGGAGTTGCCCAAATCGCGCATCAACGCCAGCATGGTAACTCAGTTCATCGACC
AGCCGGTCTGCTTCGTAGGGAGGCTGGAGAAGATTCATCCCACTGGAAAAATGTTTATTCTTTC
AGATGGAGAAGGAAAAAATGTAACCATTGAGTTGATGGAGCCTCTTGATGAAGAAATCTCTGGA
ATCGTGGAAGTGGTTGGAAGAGTCACAGGCAAAGCAACCATTATGTGTGTCTCTTACATCCAGT
TTAAAGAAGATAACCATCCTTTTGATCTTGGACTTTATAATGAAGCTGTGAAAATTATCCATGA
GTTCCCTCAGTATTTTCCTTTGGGTGTTGTGCAGCATGGTTGAACCTGATGAATTTTATGATTG
CAAATAAACTACATTGAAGACTATTAATGGAGGCCCCTGATACTTGAGGAAGAGATTCTTGTGA
TTTTTTTTAATGTTTAAAACATTTCTTTAAATTTTTAAAGAAAAAGTTCAATTTCATTAGCCTA
ACTTTATCTGATCTTCCAGTATGTCATTTTTGATGGAACTGGAATATTGACACTTCTCACCTAG
TCTTTGTAAAGAATCACATCTCTGGCATATGGTCAGATTAGATGCAAGAATGAAGCAGTTGGCT
GAGTTTTAGTTTTCTATTATTAATAAAAGTGTAAAAG

hide sequence

Protein Sequences


Protein RefSeqs	XP_020958082	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000022985
	ENSSSCP00000022985.1
	ENSSSCP00005017959.1
	ENSSSCP00015007565.1
	ENSSSCP00025016494.1
	ENSSSCP00030021195.1
	ENSSSCP00035045973.1
	ENSSSCP00040019810.1
	ENSSSCP00045005422.1
	ENSSSCP00050044504.1
	ENSSSCP00055030349.1
	ENSSSCP00060025937.1
	ENSSSCP00065018042.1
	ENSSSCP00070017702.1
	ENSSSCP00070017712.1

RefSeq Acc Id:	XP_020958082 ⟸ XM_021102423
- UniProtKB:	A0A4X1TNF0 (UniProtKB/TrEMBL), I3LFZ2 (UniProtKB/TrEMBL), A0A4X1TQY7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVDVMELPKSRINASMVTQFIDQPVCFVGRLEKIHPTGKMFILSDGEGKNVTIELMEPLDEEIS GIVEVVGRVTGKATIMCVSYIQFKEDNHPFDLGLYNEAVKIIHEFPQYFPLGVVQHG hide sequence

Ensembl Acc Id:

ENSSSCP00000022985 ⟸ ENSSSCT00000027813

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000023886	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00005018640	UniProtKB/TrEMBL
	ENSSSCG00015014575	UniProtKB/TrEMBL
	ENSSSCG00025028709	UniProtKB/TrEMBL
	ENSSSCG00030033957	UniProtKB/TrEMBL
	ENSSSCG00035078154	UniProtKB/TrEMBL
	ENSSSCG00040035193	UniProtKB/TrEMBL
	ENSSSCG00045004855	UniProtKB/TrEMBL
	ENSSSCG00050074646	UniProtKB/TrEMBL
	ENSSSCG00055019522	UniProtKB/TrEMBL
	ENSSSCG00060044636	UniProtKB/TrEMBL
	ENSSSCG00065031468	UniProtKB/TrEMBL
	ENSSSCG00070011026	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000027813	ENTREZGENE
	ENSSSCT00000027813.3	UniProtKB/TrEMBL
	ENSSSCT00005029495.1	UniProtKB/TrEMBL
	ENSSSCT00015019353.1	UniProtKB/TrEMBL
	ENSSSCT00025038986.1	UniProtKB/TrEMBL
	ENSSSCT00030047023.1	UniProtKB/TrEMBL
	ENSSSCT00035106643.1	UniProtKB/TrEMBL
	ENSSSCT00040047357.1	UniProtKB/TrEMBL
	ENSSSCT00045008029.1	UniProtKB/TrEMBL
	ENSSSCT00050102191.1	UniProtKB/TrEMBL
	ENSSSCT00055038201.1	UniProtKB/TrEMBL
	ENSSSCT00060060533.1	UniProtKB/TrEMBL
	ENSSSCT00065042559.1	UniProtKB/TrEMBL
	ENSSSCT00070021412.1	UniProtKB/TrEMBL
	ENSSSCT00070021422.1	UniProtKB/TrEMBL
Gene3D-CATH	2.40.50.140	UniProtKB/TrEMBL
InterPro	NA-bd_OB-fold	UniProtKB/TrEMBL
	Rfa2	UniProtKB/TrEMBL
NCBI Gene	RPA3	ENTREZGENE
PANTHER	REPLICATION PROTEIN A 14 KDA SUBUNIT	UniProtKB/TrEMBL
	REPLICATION PROTEIN A3	UniProtKB/TrEMBL
Pfam	Rep_fac-A_3	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50249	UniProtKB/TrEMBL
UniProt	A0A4X1TNF0	ENTREZGENE, UniProtKB/TrEMBL
	A0A4X1TQY7	ENTREZGENE, UniProtKB/TrEMBL
	I3LFZ2	ENTREZGENE
UniProt Secondary	I3LFZ2	UniProtKB/TrEMBL
VGNC ID	VGNC:92415	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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