CLDN3 (claudin 3) - Rat Genome Database
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Gene: CLDN3 (claudin 3) Sus scrofa
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Symbol: CLDN3
Name: claudin 3
RGD ID: 13921538
Description: ENCODES a protein that exhibits identical protein binding (inferred); structural molecule activity (inferred); INVOLVED IN positive regulation of cell junction assembly (ortholog); response to ethanol (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); Intestinal Reperfusion Injury (ortholog); FOUND IN apical junction complex (ortholog); cell-cell junction (ortholog); cytoplasm (ortholog); INTERACTS WITH amino acid; deoxynivalenol; diquat
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: claudin-3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl311,019,295 - 11,019,960 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1311,019,073 - 11,020,102 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2310,715,404 - 10,716,250 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
amino acid  (EXP)
deoxynivalenol  (EXP)
diquat  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

Genomics

Comparative Map Data
CLDN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl311,019,295 - 11,019,960 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1311,019,073 - 11,020,102 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2310,715,404 - 10,716,250 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CLDN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl773,768,997 - 73,770,270 (-)EnsemblGRCh38hg38GRCh38
GRCh38773,768,997 - 73,770,270 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37773,183,327 - 73,184,600 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36772,821,263 - 72,822,512 (-)NCBINCBI36hg18NCBI36
Build 34772,627,978 - 72,629,227NCBI
Celera768,661,514 - 68,662,787 (-)NCBI
Cytogenetic Map7q11.23NCBI
HuRef769,065,982 - 69,067,255 (-)NCBIHuRef
CHM1_1773,329,029 - 73,330,302 (-)NCBICHM1_1
CRA_TCAGchr7v2772,516,399 - 72,517,672 (-)NCBI
Cldn3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395135,015,068 - 135,016,330 (+)NCBIGRCm39mm39
GRCm385134,986,214 - 134,987,476 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5134,986,214 - 134,987,472 (+)EnsemblGRCm38mm10GRCm38
MGSCv375135,462,084 - 135,463,342 (+)NCBIGRCm37mm9NCBIm37
MGSCv365135,270,841 - 135,272,099 (+)NCBImm8
Celera5131,997,044 - 131,998,302 (+)NCBICelera
Cytogenetic Map5G2NCBI
cM Map574.93NCBI
Cldn3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01221,831,341 - 21,832,813 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1221,831,342 - 21,832,813 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01223,849,259 - 23,850,731 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1223,471,431 - 23,472,903 (-)NCBICelera
Cytogenetic Map12q12NCBI
CLDN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1780,924,338 - 80,925,761 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl780,924,731 - 80,925,393 (-)Ensemblpanpan1.1panPan2
CLDN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.166,534,229 - 6,535,237 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Cldn3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365432,952,054 - 2,953,313 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CLDN3
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1289,301,312 - 9,303,496 (+)NCBI
ChlSab1.1 Ensembl289,302,446 - 9,303,108 (+)Ensembl
Cldn3
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474014,065,172 - 14,066,432 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system hemolymphoid system nervous system renal system reproductive system respiratory system
High
Medium 3
Low 5 3 3 3 2 3 1
Below cutoff 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000027640   ⟹   ENSSSCP00000064612
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl311,019,295 - 11,019,960 (-)Ensembl
RefSeq Acc Id: NM_001160075   ⟹   NP_001153547
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1311,019,073 - 11,020,102 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001153547 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAT42132 (Get FASTA)   NCBI Sequence Viewer  
  ACP19336 (Get FASTA)   NCBI Sequence Viewer  
  ACP19337 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001153547   ⟸   NM_001160075
- UniProtKB: C3VPJ6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000064612   ⟸   ENSSSCT00000027640


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000035928 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000064612 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000027640 ENTREZGENE, UniProtKB/TrEMBL
InterPro Claudin UniProtKB/TrEMBL
  Claudin3 UniProtKB/TrEMBL
  Claudin_CS UniProtKB/TrEMBL
  PMP22/EMP/MP20/Claudin UniProtKB/TrEMBL
KEGG Report ssc:431781 UniProtKB/TrEMBL
NCBI Gene CLDN3 ENTREZGENE
PANTHER PTHR12002 UniProtKB/TrEMBL
Pfam PMP22_Claudin UniProtKB/TrEMBL
PRINTS CLAUDIN3 UniProtKB/TrEMBL
PROSITE CLAUDIN UniProtKB/TrEMBL
UniGene Ssc.9102 ENTREZGENE
  Ssc.93114 ENTREZGENE
UniProt A0A5G2QJG3_PIG UniProtKB/TrEMBL
  C3VPJ5_PIG UniProtKB/TrEMBL
  C3VPJ6 ENTREZGENE, UniProtKB/TrEMBL