ALB (albumin) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: ALB (albumin) Sus scrofa
Analyze
Symbol: ALB
Name: albumin
RGD ID: 14115923
Description: ENCODES a protein that exhibits small molecule binding; DNA binding (ortholog); enterobactin binding (ortholog); INVOLVED IN cellular response to starvation (ortholog); maintenance of mitochondrion location (ortholog); negative regulation of apoptotic process (ortholog); PARTICIPATES IN forkhead class A signaling pathway; organophosphate response pathway; ASSOCIATED WITH Acute Coronary Syndrome (ortholog); acute kidney failure (ortholog); Acute Liver Failure (ortholog); FOUND IN extracellular space; basement membrane (ortholog); protein-containing complex (ortholog); INTERACTS WITH ammonia; clofibrate; cylindrospermopsin
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: serum albumin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl869,531,487 - 69,721,696 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1869,643,427 - 69,663,152 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2873,610,472 - 73,630,119 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap8q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Coronary Syndrome  (ISO)
acute kidney failure  (ISO)
Acute Liver Failure  (ISO)
Acute Lung Injury  (ISO)
adult respiratory distress syndrome  (ISO)
Albuminuria  (ISO)
alcoholic hepatitis  (ISO)
allergic disease  (ISO)
Analbuminemia  (ISO)
angioedema  (ISO)
Animal Disease Models  (ISO)
anuria  (ISO)
aseptic meningitis  (ISO)
autoimmune thrombocytopenic purpura  (ISO)
azoospermia  (ISO)
biliary tract benign neoplasm  (ISO)
blood protein disease  (ISO)
brain disease  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
Burns  (ISO)
Carcinoid Tumor  (ISO)
cardiovascular system disease  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
cholangiocarcinoma  (ISO)
cholestasis  (ISO)
Chronic Allograft Nephropathy  (ISO)
Colorectal Neoplasms  (ISO)
congestive heart failure  (ISO)
COVID-19  (ISO)
Delayed Hypersensitivity  (ISO)
diabetic angiopathy  (ISO)
Diabetic Nephropathies  (ISO)
Drug-Related Side Effects and Adverse Reactions  (ISO)
echinococcosis  (ISO)
Ehlers-Danlos syndrome cardiac valvular type  (ISO)
end stage renal disease  (ISO)
epilepsy  (ISO)
esophageal varix  (ISO)
Experimental Arthritis  (ISO)
Experimental Liver Cirrhosis  (ISO)
Experimental Sarcoma  (ISO)
extrahepatic cholestasis  (ISO)
Familial Dysalbuminemic Hyperthyroxinemia  (ISO)
familial hyperlipidemia  (ISO)
Fibrosis  (ISO)
gastric cardia adenocarcinoma  (ISO)
glomerulonephritis  (ISO)
Hantavirus hemorrhagic fever with renal syndrome  (ISO)
heart disease  (ISO)
hemolytic-uremic syndrome  (ISO)
Hepatic Insufficiency  (ISO)
hepatitis  (ISO)
hepatocellular carcinoma  (ISO)
Hepatomegaly  (ISO)
HIV Seropositivity  (ISO)
human immunodeficiency virus infectious disease  (ISO)
Hydrops Fetalis  (ISO)
hypertension  (ISO)
hyperthyroxinemia  (ISO)
Hypoalbuminemia  (ISO)
Hypoproteinemia  (ISO)
Hypotension  (ISO)
interstitial nephritis  (ISO)
Kabuki Syndrome 1  (ISO)
Keloid  (ISO)
kidney disease  (ISO)
leukemia  (ISO)
liver cirrhosis  (ISO)
lung adenocarcinoma  (ISO)
Lung Injury  (ISO)
lung non-small cell carcinoma  (ISO)
membranoproliferative glomerulonephritis  (ISO)
membranous glomerulonephritis  (ISO)
mental depression  (ISO)
middle cerebral artery infarction  (ISO)
multiple myeloma  (ISO)
muscular disease  (ISO)
Myocardial Reperfusion Injury  (ISO)
nephritis  (ISO)
nephrosis  (ISO)
nephrotic syndrome  (ISO)
obstructive jaundice  (ISO)
Occupational Diseases  (ISO)
Pain  (ISO)
pancreas disease  (ISO)
pancreatic cancer  (ISO)
pancreatic ductal carcinoma  (ISO)
Pancreatic Fistula  (ISO)
pancreatitis  (ISO)
Paroxysmal Atrial Fibrillation  (ISO)
Perennial Allergic Rhinitis  (ISO)
pneumonia  (ISO)
Poisoning  (ISO)
Postoperative Complications  (ISO)
pre-eclampsia  (ISO)
primary biliary cholangitis  (ISO)
protein-energy malnutrition  (ISO)
proteinuria  (ISO)
psoriasis  (ISO)
pulmonary emphysema  (ISO)
Reperfusion Injury  (ISO)
respiratory system disease  (ISO)
Reye syndrome  (ISO)
root caries  (ISO)
Sepsis  (ISO)
Serum Sickness  (ISO)
Stevens-Johnson syndrome  (ISO)
Stomach Neoplasms  (ISO)
Stroke  (ISO)
suppurative otitis media  (ISO)
thrombocytopenia  (ISO)
twin-to-twin transfusion syndrome  (ISO)
urticaria  (ISO)
uveitis  (ISO)
Zollinger-Ellison syndrome  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:1362182   PMID:2728927   PMID:3174440   PMID:8101068   PMID:14681463   PMID:17145712   PMID:21147258  


Genomics

Comparative Map Data
ALB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl869,531,487 - 69,721,696 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1869,643,427 - 69,663,152 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2873,610,472 - 73,630,119 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap8q12NCBI
ALB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38473,404,287 - 73,421,482 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl473,397,114 - 73,421,482 (+)EnsemblGRCh38hg38GRCh38
GRCh37474,270,004 - 74,287,199 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36474,488,870 - 74,505,996 (+)NCBINCBI36hg18NCBI36
Build 34474,635,040 - 74,652,167NCBI
Celera471,629,770 - 71,646,928 (+)NCBI
Cytogenetic Map4q13.3NCBI
HuRef470,081,138 - 70,098,456 (+)NCBIHuRef
CHM1_1474,306,138 - 74,323,296 (+)NCBICHM1_1
T2T-CHM13v2.0476,747,989 - 76,765,185 (+)NCBI
Alb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39590,608,729 - 90,624,461 (+)NCBIGRCm39mm39
GRCm39 Ensembl590,608,756 - 90,624,461 (+)Ensembl
GRCm38590,460,870 - 90,476,602 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl590,460,897 - 90,476,602 (+)EnsemblGRCm38mm10GRCm38
MGSCv37590,889,915 - 90,905,629 (+)NCBIGRCm37mm9NCBIm37
MGSCv36591,536,101 - 91,551,800 (+)NCBImm8
Celera588,622,143 - 88,637,838 (+)NCBICelera
Cytogenetic Map5E1NCBI
cM Map544.7NCBI
Alb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21417,607,397 - 17,622,814 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1417,607,381 - 17,622,836 (-)Ensembl
Rnor_6.01419,176,275 - 19,191,793 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1419,176,277 - 19,191,863 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01419,083,045 - 19,098,563 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41419,126,935 - 19,142,214 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11419,126,964 - 19,142,199 (-)NCBI
Celera1416,973,318 - 16,987,975 (-)NCBICelera
Cytogenetic Map14p22NCBI
Alb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554479,327 - 21,212 (-)NCBIChiLan1.0ChiLan1.0
ALB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1456,605,322 - 56,622,418 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl456,605,322 - 56,622,418 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0450,773,244 - 50,790,474 (-)NCBIMhudiblu_PPA_v0panPan3
ALB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11362,133,747 - 62,169,349 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1362,053,814 - 62,294,709 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1361,822,278 - 61,838,968 (+)NCBI
ROS_Cfam_1.01362,962,229 - 62,978,876 (+)NCBI
ROS_Cfam_1.0 Ensembl1362,962,188 - 62,978,873 (+)Ensembl
UMICH_Zoey_3.11362,573,750 - 62,590,441 (+)NCBI
UNSW_CanFamBas_1.01362,066,831 - 62,083,527 (+)NCBI
UU_Cfam_GSD_1.01363,202,547 - 63,219,341 (+)NCBI
ALB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1721,872,036 - 21,890,095 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl721,876,132 - 21,891,407 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666084909,150 - 931,036 (-)NCBIVero_WHO_p1.0
Alb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473534,104,537 - 34,123,624 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462473534,105,237 - 34,123,479 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 1 1 21 1 1
Below cutoff 9 4 2 5 1 2 1 1 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000009802   ⟹   ENSSSCP00000009549
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl869,644,125 - 69,721,696 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000050020   ⟹   ENSSSCP00000042865
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl869,643,470 - 69,721,696 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000050096   ⟹   ENSSSCP00000034783
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl869,643,442 - 69,660,778 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000057761   ⟹   ENSSSCP00000053712
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl869,531,487 - 69,663,149 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000064748   ⟹   ENSSSCP00000045270
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl869,643,470 - 69,721,696 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000093326   ⟹   ENSSSCP00000076001
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl869,643,442 - 69,663,017 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000099055   ⟹   ENSSSCP00000076774
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl869,582,870 - 69,663,149 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000105871   ⟹   ENSSSCP00000074991
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl869,643,442 - 69,660,778 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000106420   ⟹   ENSSSCP00000076177
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl869,643,442 - 69,660,778 (+)Ensembl
RefSeq Acc Id: NM_001005208   ⟹   NP_001005208
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1869,643,472 - 69,663,150 (+)NCBI
Sequence:
RefSeq Acc Id: XR_002346365
RefSeq Status:
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1869,643,427 - 69,663,152 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001005208 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA30988 (Get FASTA)   NCBI Sequence Viewer  
  AAT98610 (Get FASTA)   NCBI Sequence Viewer  
  ABM92961 (Get FASTA)   NCBI Sequence Viewer  
  CAA30970 (Get FASTA)   NCBI Sequence Viewer  
  P08835 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001005208   ⟸   NM_001005208
- Peptide Label: precursor
- UniProtKB: P08835 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSSSCP00000042865   ⟸   ENSSSCT00000050020
RefSeq Acc Id: ENSSSCP00000034783   ⟸   ENSSSCT00000050096
RefSeq Acc Id: ENSSSCP00000045270   ⟸   ENSSSCT00000064748
RefSeq Acc Id: ENSSSCP00000009549   ⟸   ENSSSCT00000009802
RefSeq Acc Id: ENSSSCP00000053712   ⟸   ENSSSCT00000057761
RefSeq Acc Id: ENSSSCP00000076001   ⟸   ENSSSCT00000093326
RefSeq Acc Id: ENSSSCP00000076774   ⟸   ENSSSCT00000099055
RefSeq Acc Id: ENSSSCP00000076177   ⟸   ENSSSCT00000106420
RefSeq Acc Id: ENSSSCP00000074991   ⟸   ENSSSCT00000105871
Protein Domains
Albumin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000008948 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005041860 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000009549.3 UniProtKB/TrEMBL
  ENSSSCP00000034783.1 UniProtKB/TrEMBL
  ENSSSCP00000042865.2 UniProtKB/TrEMBL
  ENSSSCP00000045270 ENTREZGENE
  ENSSSCP00000045270.1 UniProtKB/TrEMBL
  ENSSSCP00000053712.2 UniProtKB/TrEMBL
  ENSSSCP00005041662.1 UniProtKB/TrEMBL
  ENSSSCP00005041679.1 UniProtKB/TrEMBL
  ENSSSCP00005041704.1 UniProtKB/TrEMBL
  ENSSSCP00005041824.1 UniProtKB/TrEMBL
  ENSSSCP00005041855.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000009802.4 UniProtKB/TrEMBL
  ENSSSCT00000050020.2 UniProtKB/TrEMBL
  ENSSSCT00000050096.2 UniProtKB/TrEMBL
  ENSSSCT00000057761.2 UniProtKB/TrEMBL
  ENSSSCT00000064748 ENTREZGENE
  ENSSSCT00000064748.2 UniProtKB/TrEMBL
  ENSSSCT00005067093.1 UniProtKB/TrEMBL
  ENSSSCT00005067118.1 UniProtKB/TrEMBL
  ENSSSCT00005067157.1 UniProtKB/TrEMBL
  ENSSSCT00005067341.1 UniProtKB/TrEMBL
  ENSSSCT00005067391.1 UniProtKB/TrEMBL
InterPro ALB/AFP/VDB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serum_albumin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serum_albumin/AFP/Afamin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serum_albumin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Serum_albumin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:396960 UniProtKB/Swiss-Prot
NCBI Gene ALB ENTREZGENE
PANTHER PTHR11385 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Serum_albumin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF Serum_albumin_subgroup UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS SERUMALBUMIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ALBUMIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ALBUMIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ALBUMIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48552 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A286ZT13_PIG UniProtKB/TrEMBL
  A0A287AFS2_PIG UniProtKB/TrEMBL
  A0A287AMK0_PIG UniProtKB/TrEMBL
  A0A287BAY9_PIG UniProtKB/TrEMBL
  A0A8D0KMA1_PIG UniProtKB/TrEMBL
  A0A8D0KMA9_PIG UniProtKB/TrEMBL
  A0A8D0KMC5_PIG UniProtKB/TrEMBL
  A0A8D0LXN5_PIG UniProtKB/TrEMBL
  A0A8D0TM45_PIG UniProtKB/TrEMBL
  ALBU_PIG UniProtKB/Swiss-Prot
  F1RUN2_PIG UniProtKB/TrEMBL
  P08835 ENTREZGENE
UniProt Secondary Q29018 UniProtKB/Swiss-Prot
  Q68NH7 UniProtKB/Swiss-Prot
VGNC ID VGNC:98911 ENTREZGENE